Why can't tyrosine be a hydrogen bond donor in physiological condition?

One of the questions I'm reviewing asks "which of the following amino acids can the oxygen group (which in the passage is part of an antitumor agent that can be a H-bond acceptor) interact with?" and the choices were: aspartate, cysteine, tyrosine, and lysine. In the explanation, it says only lysine can be a H-bond donor but doesn't that also apply to tyrosine?

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πŸ‘€︎ u/iamfromjobland
πŸ“…︎ Jan 28 2022
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Underweight - Physiological conditions from CPTSD

I understand that eating disorders can occur from cptsd, abuse, neglect etc.

What about physiological issues? Nutritional absorption etc.

I have enormous difficulty putting on weight. I am an adult male. I weigh under 100lbs.

I eat 500-600 calories a day over RDI. I am in my 30's and weigh as much as a 13yo.

Can this be caused by CPTSD? Can emotional neglect affect how my body absorbs calories?

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πŸ‘€︎ u/ikenowain
πŸ“…︎ Dec 02 2021
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We don't just have cptsd we have physiological conditions to. We shake and feel the anxiety of our past physically. We need ibogaine yearly. open.spotify.com/episode/…
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πŸ“…︎ Dec 01 2021
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πŸ’‰ Researchers create a microscopic chip that can be injected into the body to monitor physiological conditions πŸ’‰
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πŸ‘€︎ u/DoctorSashaGrey
πŸ“…︎ Aug 03 2021
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We don't just have cptsd we have physiological conditions to. We shake and feel the anxiety of our past physically. We need ibogaine yearly. open.spotify.com/episode/…
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πŸ‘€︎ u/KillerSpaceBunny
πŸ“…︎ Dec 02 2021
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Open-source Brain-computer interface with the embedded board to monitor the physiological subject's condition and environmental parameters researchgate.net/publicat…
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πŸ‘€︎ u/SpecificAd3444
πŸ“…︎ Nov 09 2021
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I’m so exhausted from convincing people this is a real, physiological condition

Mini rant time. I’m so drained from constantly having to convince my family and some of my friends that what I’m going through is a physiological issue that I don’t have control over. I feel like I’m constantly on trial trying to prove myself and my symptoms. They do validate some of my symptoms like when I wake up out of dead sleep with a 150 bpm HR, but they always manage to slip in a comment about how I should go see a psychiatrist/work through my anxiety.

I will admit I 100% have anxiety from experiencing all of these extreme symptoms. I’ve recently started getting nervous about being out & about or in a car and getting symptoms which is definitely psychological. But it all stems from my very real symptoms. It doesn’t help that the first cardiologist I went to before I was diagnosed told me I was too young to have issues and laughed in my face when I explained my symptoms & told me to throw away my Apple Watch. Conveniently my mom was in the room for that.

I empathize for anyone going through something similar & owe this subreddit most of my sanity for validating how I feel πŸ’œ

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πŸ‘€︎ u/kp091901
πŸ“…︎ Aug 10 2021
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Open-source Brain-computer interface with the embedded board to monitor the physiological subject's condition and environmental parameters

This manuscript presented a brain-computer interface (STM32 and ADS1299) with an embedded board with sensors to monitor the subject's state and environment. To reduce power consumption and device size, we used sensors made in Micro-Electro-Mechanical Systems technology (MEMS)-a gyroscope, accelerometer, and environmental monitoring sensors: CO2, temperature, humidity, ambient sound, and pulse and blood oxygen saturation. Data from the device is transmitted using TCP-PI (UART by Bluetooth) protocol to a computer or mobile device. Open-source https://github.com/Ildaron/ironbci

https://www.researchgate.net/publication/356024518_ironbci_-Open-source_Brain-computer_interface_with_the_embedded_board_to_monitor_the_physiological_subject's_condition_and_environmental_parameters_arXiv211103656

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πŸ‘€︎ u/SpecificAd3444
πŸ“…︎ Nov 09 2021
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Phospholipases & reactive oxygen species derived lipid biomarkers in healthy & diseased humans & animals: Lysophosphatidylcholine focus::: converted lipid biomarkers by action of phospholipases & reactive oxygen species, activated or released under physiological & pathophysiological conditions... frontiersin.org/articles/…
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πŸ‘€︎ u/DomPachino
πŸ“…︎ Oct 24 2021
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Redditers who suffer from Misophonia, that is a disorder in which certain sounds trigger emotional or physiological responses, what sounds trigger you and what do you do to deal with this condition?
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πŸ“…︎ May 07 2021
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Physiological condition is the death card...

So I've been dealing with a lot of changes lately. My dad committed suicide and I've had to let go of things in the past in a big major way. I'm planning to get married soon too. I find that I'm bedridden lately due to the emotional stress and heartbreaks.

I asked how my physiological state was and I got Death.

I asked if I was sick and got Knight of Cups.

Then I did a three card spread asking what's going on with my body and I got... Ten of Pentacles (family/ buildup of something) Ace of Wands (deciding) Eight of Cups (to do something better with one's life)

Am I stressed out emotionally and physically because I am being distant or because they are being distant? Maybe it's both.

I think my emotional state is affecting my heath. Any thoughts on this?

Edit: I asked further questions...

Will a doctor help me heal? Seven of Pentacles (hard work with little reward)

Will a change in diet help me heal? Page of wands reversed (it's not what you're looking for)

What about exercise? The Emperor (you have to do that anyway)

What about sleep? The World (fulfilled potential, that's what will help ultimately)

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πŸ“…︎ Aug 09 2021
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TIL William Shatner developed tinnitis after an explosion on the set of 'Star Trek.' He coped with the condition by wearing a white noise device, which diminishes the physiological response to repeated stimuli. He became the official spokesman for tinnitis and talked someone down from suicide. mentalfloss.com/article/8…
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πŸ‘€︎ u/gmcl86
πŸ“…︎ May 24 2018
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Clinical Depression is a neurological condition. How then is β€˜talk therapy’ even relevant? You wouldn’t send a diabetic or cancer patient to a therapist to cure their physiological ailment. Therapy just seems like the β€˜accepted’ course of action but is basically counter-intuitive and costly.

36m, I’ve suffered from major depressive disorder since my early teenage years. I’ve seen a number of extremely empathetic and well versed therapists in that time and while it can feel validating to speak with a professional that can intellectually understand some of my struggles, I was going to therapy with the understanding that this was a medical intervention to cure me of my depression so that I could lead a β€˜normal’ life with β€˜normal’ life difficulties but general happiness or at least contentment.

Looking back, I feel like it was never made clear to me that the condition I suffered from wasn’t really (or entirely) psychological in nature but rather a neurological/medical condition due in part to chemical deficits in my brain. And that talking about my neurological condition was NEVER going to solve the problem. In the same way that talking about diabetes doesn’t cure diabetes.

Now, while my depression has been extremely treatment resistant over the past two decades, I finally found a medication (the MAOI Parnate) that has finally provided me with some semblance of relief. But this is sort of my point, medication is a medical intervention. A chemical intervention for a chronic physiological condition. And this medication has done more for me in 3 months than 20+ years of therapy. In hindsight, the concept of talking someone through a disease of the brain seems especially asinine to me.

Furthermore, I feel like therapists in general fail to make the distinction to their clients, and that the relief they can expect to experience with intensive talk therapy is proportional to their affliction. Traumatic breakup? Yes, therapy can be extremely beneficial. Grief? Yes. Anger issues? Yes. Trouble making friends, maintaining relationships? Yes. Chemically based chronic depressive disorder? Absolutely not.

It’s not that they can’t empathize or commiserate with you (which can feel helpful), it’s that intensive talk therapy with no relief of neurological symptoms can feel like yet another failure in the quest to rid yourself of severe depression. In my experience, this can ultimately make things worse. I just wish therapists in general would be more honest with their patients (and themselves) when it comes to treatment expectations and outcomes for people with circumstantial depression vs people with chemical deficits in their brain. Sometimes I’m not even sure that they themselves are able to make the distinction. Or even worse...that some know and tell

... keep reading on reddit ➑

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πŸ‘€︎ u/odetomaybe
πŸ“…︎ Jan 25 2021
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"Breathing is one of the most fundamental physiological functions of the human body. Moreover, it is an integral component of interoceptive processing, i.e. the sensing of the physiological condition of the body" ncbi.nlm.nih.gov/pmc/arti…
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πŸ‘€︎ u/Heyballsbananafan
πŸ“…︎ Jul 12 2020
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TIL: carbon monoxide plays critical roles in the body under physiological conditions, acting as a vasodilator, neurotransmitter, and regulator of circadian rhythm among other important functions. ncbi.nlm.nih.gov/pmc/arti…
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πŸ‘€︎ u/ellljae
πŸ“…︎ Jun 07 2020
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Quantifying liquid-liquid phase separation property of chromatin under physiological conditions using Hi-MS and Hi-C biorxiv.org/content/10.11…
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πŸ‘€︎ u/sburgess86
πŸ“…︎ Dec 08 2020
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Does AAMC consider a Histidine a positively charged amino acid at physiological conditions?

Technically its side chain is pka 6.0 so its mainly uncharged but most of the tables/ resources I look at give it the +1 and group it with lysine and arginine. Seems like something that it depends on who you ask. Has anyone ran into a question in AAMC content that would clarify their view on histidine?

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πŸ‘€︎ u/btron3030
πŸ“…︎ Apr 24 2020
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'Vital exhaustion' is more than a bad night’s sleep or snapping in a meeting β€” it’s a β€œgrowing epidemic” and chronic condition that has a potentially deadly cost. New research illuminates how burnout can manifest in tangible, physiological ways. inverse.com/article/62278…
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πŸ‘€︎ u/ngt_
πŸ“…︎ Jan 14 2020
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Physiological Test for Autism Proves Effective Independent of Co-occurring Conditions news.rpi.edu/content/2020…
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πŸ‘€︎ u/Cealdi
πŸ“…︎ Sep 01 2020
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[Preclinical] Does Portosystemic anastomosis in physiological conditions ?

Hello,

When there is portal hypertension, blood flows "backwards" to others veins like the rectal veins, splenic veins, gastric veins, oesophagial veins or even the splenorenal vein.
I would like to know if these anastomosis actually exist when everything is ok, or does these shunts/anastomosis created when we have this hypertension.

Thank you in advance !

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πŸ‘€︎ u/Korimizu06
πŸ“…︎ Oct 15 2020
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Am I suffering from a mental illness or some sort of physiological condition regarding an ex gf?

Sorry if this is too long, but if you take the time to read it, thank you.

Don’t feel the need to go too into detail, but basically a few years ago the love of my life broke up with me after two years. She did it in a completely uncharacteristic manner and only 5 days after a vacation together. This absolutely devastated me and threw me in a vile spin of confusion, sadness, regret, anger, hatred and emptiness. We were the best of friends and had countless memories together. To be clear, I wasn’t the clingy one either.

The feelings I had at the time of the breakup were much stronger than I have now, of course, but it seems like the only way my mind can get a rational grasp of the situation is that this girl just vanished from existence or something, and was just taken away somewhere else.

It’s to the point where some nights I will have dreams about her and the memories we shared with each other. Honestly kinda feels like cobb and mal from inception, where I can feel her touch and breath and everything in my dreams, which sometimes I hate waking up from. It’s gotten to the point now where I want to stay in those dreams with her cause when I wake up I’ll usually only remember small parts of the dream.

I’m not dysfunctional or something. I work in construction and (arguably) live a pretty healthy lifestyle, besides the fact that I don’t date. I have passions, hobbies etc. But these feelings and memories of this girl get recycled through these dreams and thoughts, they just make me wanna cry so bad sometimes. (which I sometimes do).

tl;dr: Sorry this is so long, but my question is, am I truly suffering from something?

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πŸ‘€︎ u/sundin--279
πŸ“…︎ Feb 06 2020
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We all have physiological conditions and they are part of our personality ,but they are not too intense and that’s why we don’t treat them
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πŸ‘€︎ u/TsonK
πŸ“…︎ May 16 2020
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Does ketose tautomerize to aldose under normal physiological condition?

In the Klein Organic Chemistry 2nd edition, it says that Tollen's Reagent is used to detect the presence of BOTH aldose and ketose (any reducing sugar), because ketose will automatically tautomerize to aldose and be oxidized by Ag+. However, I see quite a few MCAT-related references saying that Tollen's reagent is only used to detect aldose. In addition, the body also has a separate epithelial transporter and liver metabolism pathway for fructose. It makes me wonder if ketose tautomerize to aldose under normal physiological condition? And what about under the in vitro chemical conditions under Tollen's Reagent? Thanks!

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πŸ‘€︎ u/discussionsarefun
πŸ“…︎ Aug 03 2019
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TIL the "lump in your throat" feeling, otherwise known as "globus hystericus," is actually something called a Cricopharyngeal spasm. It is extremely rare for it to indicate a serious condition, and the only known physiological cause is anxiety en.wikipedia.org/wiki/Cri…
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πŸ“…︎ May 22 2018
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An international team spearheaded by researchers at McGill University has discovered a biological mechanism that could explain heightened somatic awareness, a condition where patients experience physical discomforts for which there is no physiological explanation. mcgill.ca/newsroom/channe…
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πŸ‘€︎ u/Wagamaga
πŸ“…︎ Jun 24 2019
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