Transfusion Reaction Puns

Just happened to me, patient coded and died. Apparently it’s 1 in 2.3 million chance of happening (dying from it) based on quick google search. Happened right at change of shift after report. Couldn’t believe it.

1.Allergic: Mechanism:preformed ABO against blood products Features:urticaria, anaphylaxis Time:within minutes to hours

Example' A 24 year old was brought to the ER after MVA.Soon after transfusion he developed shortness of breath,wheezes are present in auscultation.Most likely diagnosis?

2.acute hemolytic: Mechanism:ABO incompatibility Features:hemoglobinuria,dic,fever Time: with in minutes to hours

Example': A patient was brought to ER after an accident.Soon after transfusion he developed dark brown urine.

Anyone who's interested can comment other transfusion reaction with examples Goal is just to reinforce stuff Thankyou

Are transfusion reactions ultra-high yield on the real thing or what? There are sooo many questions about them in UWorld.

Why is IgE called anti-IgA antibody (FA depicts so)? IgA deficient people shouldn't be given plasma with IgA, but I don't understand why it causes type 1 hypersensitivity reaction. Am i missing something?

I, for the life of me, cannot keep these transfusion adverse reactions straight in my head. Anyone have any helpful tips or good resources to get these questions right?? Or do I just have to straight up memorize this? 😞

What is the best next step to do. ?

Call the blood bank for cross matching or check for coombs/free HB?

Have you ever seen this reaction? Did the pt experience apprehension?

I was going through FA2020 to refresh my memory on some of them and it has taken out a good amount of detail from what was in the BG Zanki cards which I think are based around FA 2017 which later had 2018 updates.

I know that for neonates, Rh antibodies in mom do the most damage, but that reminded me of someone saying that ABO antibodies in ADULT transfusion reactions are worse than Rh reactions. Is this true? If so, why would Rh antibodies be so much worse during gestation but relatively more okay in adulthood? Thank you so much!

Is it just me or is this anki card ('Text' field) phrased incorrectly?

The 'Extra' in red font is what I wrote to define the mechanism for FNHTR based on other sources.

What do other people think about this card?

u/AnkingMed

https://preview.redd.it/ru6xkyo78qf41.png?width=3744&format=png&auto=webp&s=65ef170d47aac3f26de04da8b85f2bba7608d822

I was thinking about this the other day. What could a doctor tell the patient’s family happened? Like what would his exact words be?

When I got home after barely eating the 6 days I was hospitalized, I’ve gained 30lbs. Has to be all fluid, anyone have tips to help the natural progression along? I’ve already lost 10 since Sunday peeing every 45 minutes or so. Lol

If a patient has a transfusion reaction, can they be transfused before the investigation is completed? What if it is an emergency?

I just had one happen to me this week. The pt. was admitted with vaginal bleeding Hgh 6.6 was ordered to transfuse 1 unit of LR PRBC. I confirmed the blood with blood bank and another nurse prior to infusion and everything matched. I started the blood transfusion and about 2 minutes in the pt. stated she had hot feet, otherwise doing fine VSS at bassline. Around 12 minutes in the pt. stated she had the “pokies” a similar feeling when she is hungover. VSS within baseline. The pt. appeared to be hyperalert and anxious at bassline, so I continued with the blood transfusion. I took my 15-minute VS and they were also stable and within the baseline. However, the pt was c/o of an itching throat and I could see some edema of the tongue and lips. I stopped the transfusion and called the rapid. The rapid lasted about two hours we administered 25mg of PO Benadryl, 0.5mg of IM epi, 25 mg of IV Benadryl, 125mg of a solumedrol, 20 mg of H2 blocker IVPB, racemic epi, an additional 0.3mg of IM epi and 25mg of IV Benadryl along with 1mg IV morphine and 0.5 IV Ativan. Then transferred here to tele.

I talked to the doctor later and told her about the 15 minutes observation period and she stated the S&S during the blood transfusion had she been notified would have told me to continue with the infusion.

Our hospital policy is to perform bassline VS 30 minutes before the unit starts. Direct Observation by RN for 15 minutes. VS at 15 minutes. VS at 45 minutes. VS at every hour on the hour of the first 15 minutes VS. VS when transfusion is ended and VS 1 hour after end time.

I started my blood at 125mL/HR so about 30mL will get transfused in that period.

My questions:

What is your hospital policy when it comes to starting blood? Does it specify at what mL/hr to start the blood?

Has anyone seen an anaphylactic blood transfusion and what was the outcome of the pt?

What is your hospital policy about transfusion reactions?

So in my school we are taught that if someone is recieving blood and have a reaction (such as hemolytic) we are to stop the infusion and start running N/S. However, I am not sure about the blood that is still in the tube after the connector for the N/S. Is it supposed to just be run through or is there some way of bypassing/removing it?

There's a long history of Vikings drinking gallons of their foe's blood, almost surely without testing what blood group the dead body is.

So I just got off a noc shift with an elderly gentleman who was admitted for symptomatic anemia. H/H about 6&25, ordered to receive 2 units over 6 hours. Came up from the ED around 0200 with the first unit hanging, BPs stable at about 145s/60s, afebrile throughout this entire ordeal.

First unit finished, I hung the second one, and pt works on going to sleep. At the 15-20 minute vitals check, my CNA reports a bp of about 114/50ish. Seemed like a bit of a drop, so i go and check for myself about 5 minutes later, and I get around 100/50, still dropping. I keep checking about every 10 minutes for the next half hour to see whats happening. 90/40 was the lowest i got. I stop the infusion, notify MD and wait. Pt is denying any other symptoms or pain. HR went up about 20 points from 80-100 and irregular. MD took a while to get back to me and he was rather wishy-washy about what he wanted to do. My biggest concern was that this guy dropped about 50mmHg systolic in 30-45 minutes. Regardless of whether other symptoms were present, my instincts told me something was wrong and to stop the infusion. I seemed to be the only one who was concerned. Talked to my charge who said she would not have stopped the infusion, and the day nurse who i gave report to said she would have increased the rate to get his bp back up, which honestly doesn't make sense to me. After holding the infusion for a total of 45 minutes, (MD ordered to hold for 30 after taking his sweet time to call me back) I got new vitals and he came back up to 115/55. He held stable around here for the rest of the infusion.

I am a relatively new floor nurse; been on this geri-psych unit for about 9 months. Have done maybe 3 transfusions throughout my career and all have gone smoothly, except this one. I have no experience with reactions, so i'm asking you, Nurssit:

Have you ever seen a reaction like this? Do you think it even was a reaction? Was I wrong to stop the infusion? Why would increasing the rate make sense?

This is perplexing me.

An experienced blood banker told me she's seen the following:

1. A transfusion reaction was reported and blood was returned to the blood bank with the infusion set and all. The blood was indeed hemolyzed and the reason was not far to seek: it had been transfused along with a bag of half normal saline (0.45%), instead of the usual 0.90%. This hypotonic solution made the RBC's swell and lyse. Investigation showed that the half normal saline bag looked just like the normal saline bag (except for the labeling) and had been put where the normal saline was usually kept.

2. Another time the RBCs were transfused with a solution of glucose instead of saline, which made them clump.

3. Another time, back in the days when only a single blood type was required, a blood banker typed two patients at once and mixed them up. He sent the wrong type up for transfusion into a patient, who fortunately was awake and alert and knew his blood type. "Hey, that's not the right type for me," he said, possibly saving his own life. The blood banker was fired. I'm glad we require two separate types now!

Anyone else got stories?

I know you can develop allergies to certain thngs from a transfusion. Like passing on a peanut allergy, but is it possible for a human to be allergic to the blood of another human?

Why does an immunocompetent recipient who share an HLA antigens with a donor is at risk of GVHD? I've read that it has something to do with the HLA haplotype of the homozygous donor and the heterozygous recipient created some reactions, but i'm not sure i fully understand. Thanks for any response.

By 1950, the major blood groups and RH would surely have been known for transfusion, (eg in North Carolina where the crash occurred)

Got one for you guys that maybe will make your eyes roll or maybe even a laugh and an eye roll.

I work in a CVICU and just got someone out of the OR today and report from anesthesia said they are anti-vax and proud of it. They were very adamant they would not receive any blood or blood product from anyone who was vaccinated from COVID-19. I think anesthesia had a nice brief conversation about it's their right to not receive blood product but if you do, you don't get a choice in that.

For those who don't know we give a LOT of blood and blood product on our unit. Just the nature of the surgeries. We are the blood banks worst enemies. Of course this person is obese and had all the issues to accompany their heart disease and wasn't an easy separation from CPB and had significant chest tube losses. I am back tomorrow and they should be awake. Wonder what there reaction will be when they are faced with the "soooo we gave you blood" conversation.

Guess they will have to be a mud blood like the rest of us 🤣

UPDATE: Guys you were hoping for juicy and I got some juicy. So turns out they were made aware of all this prior to signing consent for sx and blood! So they signed consent for blood. They are awake and extubated. They did have to receive blood for low Hgb from chest tube losses and probably dilutional because they got a good amount of fluid.

Well let me tell you on rounds this morning the doctors made them aware of said transfusion and boy oh boy that went over nicely 🙃 We are shouting and cursing saying we have now made them magnetic and how it will be unsafe for them to return home to their family. (This is all if they got vaccinated blood, which we don't even know). There are immanent threats of leaving AMA (still have chest tubes draining and CXR of lungs looked not great as they are a smoker). Feeling like this is a bluff threat but you never know with these people. Lol

Or do they give you someone else's blood since it was already "prepared"?

I was told that I might have complications after delivery if I ever needed a blood transfusion. My pregnancy has been going well so far, though I know things can change last minute. I'm just wondering how people's experience was like getting a blood transfusion.

Is it usually predicted they need blood in advance or is it usually an emergency? Are there alternatives to blood transfusions if someone is told they could potentially have issues? If someone has had issues with blood transfusions, do they usually just stop it and give fluids or things like IV Benadryl if needed?

Hi Reddit,

I can’t believe this is happening, but I was told by my son’s pediatrician that he has leukemia about 12 hours ago.

Up until Thursday last week, he was a happy, healthy, normal acting 5 year old. Then, on Friday, he we found a red rash (petechiae) on his arms, legs, and back of neck. We saw an urgent care who told us not to worry and that it’s just because his pajamas are too tight at night. Something in me decided to get a second (and third) opinion and I did.

His pediatrician ordered routine blood work which came back late yesterday afternoon and showed extremely low platelets (22k), low hemoglobin (8.1), elevated white blood cells, and elevated liver enzymes (AST). He told me it’s leukemia and sent us to the nearest children’s hospital.

My son is scared (and so am I). We spent most of last night in the ER and it was horrific during this pandemic. So many sick kids everywhere. We wore N95 masks and face shields but it’s still so scary.

He’s now been admitted and is in a pediatric oncology unit. He’s had a 103F fever, distended abdomen, liver swelling, dark yellow urine (smells like rotten eggs), and I just woke up after a long night of trying to sleep 15 minutes at a time.

My worst fear is coming true: it wasn’t all a dream. I tried biting my tongue and pinching myself and… this is real.

I’ve been honest with my son that he’s very sick and the doctors are going to give him medicine to make him feel better. I told him there’s some germs inside that we need to wash away and he gets it. I’m trying not to let him see how sad/scared/terrified I am right now.

I have no one to talk to, except my wife who is crying her eyes out at home. I don’t know if we should be on the next flight to St. Jude or stay where we’re at. The nurses tell me this unit specializes in childhood leukemia and people come from elsewhere in the state for treatment here.

We’re in this awkward waiting game where he still hasn’t been seen by an oncologist, nor do we know what type of leukemia it is yet. The tests will come back in a few days.

I just don’t know who to turn to. Any advice, prayers, thoughts or internet hugs would mean a lot to me.

Thanks guys.

Edit: Thanks to everyone who has posted on this thread. There’s so much valuable information here and my wife and I have been taking lots of notes. My son is now starting day #3 after admission. His liver enzymes are still elevated, platelets were low and then jumped up after the transfusion but have since come ba

I’m due to get an infusion on Thursday And I’m so scared. Has anyone here had one??

Note: I have severe health anxiety and dealing with tremendous amounts of mental health issues. (This could be a cause for such issues) So I’m absolutely terrified about how it will make me feel.

So here's a place I never thought I would be posting. I hope this is okay, it seemed like the best fit. Sorry if I ramble. For years, if I ever dared to bring up to my parents that I was hurt about something, the conversation always ended with me thinking "yeah, they're right! It IS all my fault!" and I either feel happy to know my place for a little while before eventually I start feeling shitty again, or I go straight to thinking I'm crazy.

This one's a doozy. For weeks I've been going back and forth between thinking I'm the crazy one who isn't doing enough, and thinking that no, this is the final straw, I'm done with them. My counsellor calls my parents pathological and tells me I need to start coming to terms with the fact that I grew up in a psychologically abusive enviroment. My husband and best friend say they're toxic and abusive. I worry that I'm misrepresenting the situation to them and not giving my family enough credit.

Also I may talk about multiple members of my family, but my mom is the one with the power. My brothers do what she says, and everything we do in our family is to ensure that she is happy.

The incident that brought me here needs a tiny bit of backstory, which is that my parents are anti-vaxxers who have been flouting the rules since the pandemic started (with the exception of wearing masks in order to go into stores, but they don't wear them anywhere else, travel during travel bans, see whoever they want, etc). My husband and I have been careful with precautions and followed every direction to the letter, particularly because he works with the public and we have immunocompromised friends.

Before Thanksgiving, we came to the decision that once again, we would not be able to attend at my parents' home for dinner, nor would we for Christmas. We've seen them for every holiday, dropping off gifts and stopping by for a chat, but they haven't come to see us once (with the exception of when we got married to drop off a gift, but that was a whole other can of worms. They're very disappointed in us for not having a wedding during a pandemic). Because this was a big decision that we knew would be painful to hear, we didn't want it to be in a text or a phonecall, but in person.

We went there but my dad wasn't home, so we spoke with my mom. She took it surprisingly well! We both got emotional and she said that even if we can't be together physically, we can't let it tear us apart as a family. I said I wanted to still be as part of their

According to researchers, the gene, Delta 32, is found in those whose European ancestors survived The Plague. It is therefore believed that the human immune system adapted to defeat the disease and that the gene was passed along to safeguard generations to come.

In 1969, in his testimony before the US Senate, Dr. Donald MacArthur effectively asked for $10 million to produce a “synthetic biological agent”. With this testimony, many believed to have found the crucial evidence that the US Department of Defence created the AIDS “virus”, with the following extract from his statement being key:

“All biological agents up to the present time are representatives of naturally occurring disease, and are thus known by scientists throughout the world. They are easily available to qualified scientists for research, either for offensive or defensive purposes.”

Considering how Delta 32 was concluded by “scientists” as protecting people from ever being able to develop AIDS, the above would lend strongly to the possibility of, not only the supposed “virus” being successfully created, but it being based on The Plague.

There is just one problem with this “conspiracy”: AIDS does not exist.

HIV/AIDS

AIDS – Acquired ImmunoDeficiency Syndrome – is supposedly caused by contracting HIV (Human Immunodeficiency Virus); only, there has, to date, been absolutely zero concrete evidence to support this claim.

Several renowned scientists and doctors, including Kary Mullis, who invented the PCR test (and made it clear at the time that the invention should never be used to test for diseases), venomously opposed the non-science that HIV caused anything – let alone AIDS.

Dr. Robert Willner was so adamant this was the case that he even injected himself with HIV on live television. He went on to repeat this act and, when he died of a sudden heart attack (read into this as you will), no trace of either HIV or AIDS were found in his blood.

Meanwhile, other auto-immune diseases with symptoms very similar to AIDS have been discovered, with “scientists” and “doctors” quick to utilise semantics (sophism) to separate them.

For my recent theory discrediting viruses, please refer to this: https://www.reddit.com/r/conspiracyNOPOL/comments/r5nys1/logic_rules_supreme/

Thought manipulation

What does all of this have to do with The Black Death?

Back then, there wasn’t any r

What is better for you O negative or you blood type. I would think that your own blood type is better but i don't really know so reddit help me.