Is there even a difference?
Saw a video where they started with hyaline cartilage but can't seem to find anywhere where it says that hyaline cartilage is involved in this process. I know it's involved in endochondral ossification by being replaced.
I couldn't really find much online. I wanted to know this because I have costochondritis which means I have inflammation in my ribs because of trauma to my cartilage.
Hyaline cartilage makes up the costo joints but if damaged, it will only be replaced by fibrocartilage. How will that affect me and affect me working out (eg- benching). Will it break more easily?
I'm getting an ultrasound guided injection of my gouty toe in 2 weeks. I'm hoping they can look for some of the features of gout that can sometimes be seen on US, like " hyperechoic surface of hyaline cartilage, hyperechoic spots and bands within soft tissues*, a “snowstorm” appearance of synovial effusion, and bone erosion*" although tbh I hope they don't see some of that. Since this will be done by my orthopedist not a rheumatologist I don't know if she will have the experience to see these things anyway.
Just curious about other's experience with US guided toe injections, and especially whether they have visualized any of these things in your gouty toe. I have had other US injections so the procedure won't bother me. I'm getting it because even when I'm not flaring I have some arthritic symptoms in that toe, especially at night, and I want to see if this will eliminate them. I've had petty good luck with long term relief from injections in other joints, in some cases lasting for years.
I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.
Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.
Do your worst!
Hi Everyone,
I hope everyone is well
No this is not the next #shortsqueeze, but everything is possible in life when you're crazy (extremely enthusiastic).
I hope you find the time to read all this research I have done. I have waited until they release their earnings before I post this and it increases my confidence even further.
Let's start with the obvious details about the company. (as of today 12/03/2021)
- Market Cap - 37.816M (Proof)
- Currently Price - $1.29 (Proof)
- 52 Week Range - $0.7500 - $7.5000 (Proof)
- Short Interest (Current Shares Short) - 1,710,000 ( 6.79 % ) (Proof)
- Shares Float - 25,190,000 (Proof)
- Owned by institutions 8.0% ( Intracoastal Capital )
- Recent buy by CEO ( Pascoe Richard W ) (Proof)
- Shares Held by Insiders - 31.98% (Proof)
- Buy rating set as of 04/03/2021 with - $5.00 (Proof)
- Last Split 1:10 Split Date May 26, 2020 - In order to merge with another company (Proof)
- Appointed Susan Windham-Bannister to the board of directors (Proof)(Her History)
- Future Looking Statement - (Proof)
- **Strengthened Balance Sheet with $25.3 Milli
They were cooked in Greece.
I'm surprised it hasn't decade.
Don't you know a good pun is its own reword?
Two muffins are in an oven, one muffin looks at the other and says "is it just me, or is it hot in here?"
Then the other muffin says "AHH, TALKING MUFFIN!!!"
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂
It really does, I swear!
Because she wanted to see the task manager.
But that’s comparing apples to oranges
And boy are my arms legs.
Heard they've been doing some shady business.
but then I remembered it was ground this morning.
Edit: Thank you guys for the awards, they're much nicer than the cardboard sleeve I've been using and reassures me that my jokes aren't stale
Edit 2: I have already been made aware that Men In Black 3 has told a version of this joke before. If the joke is not new to you, please enjoy any of the single origin puns in the comments
They’re on standbi
A play on words.
My daughter, Chewbecca, not so much.
Pilot on me!!
And now I’m cannelloni
HSTO
“Restoring Function Enhancing Lives”
HSTO is a company focused on developing potential first in class restorative therapeutics that ignite the body's natural process to repair and maintain healthy biological function. Their technology is based on the discovery that growing fibroblast cells under simulated embryonic conditions induces them to become multipotent stem cells. The environment created by Histogen Inc's proprietary process mimics the conditions within the womb – very low oxygen and suspension. When cultured under these conditions, the induced multipotent stem cells generate biological materials that stimulate a patient’s own stem cells to activate and regenerate tissue. This technology allows the company numerous applications and approaches allowing for a continuum of introduction opportunities such as hair growth, skin care, orthopedics, and wound healing.
Proof of concept for their bio-tech
Product Pipeline
Product outlook taken from their Forward Looking Statement
CCM which has already reached the market has offered the company general cash flow. While the cash flow is not great it has allowed them to have light cash on hand.
HST 001
HST 001 has great implications for regenerative hair growth. Conveniently HSTO is partnered with Huapont, which is a Chinese based company. China’s cosmetic sales reached 299.2 billion in the most recent report I could find from 2019. China is also believed to have the largest male consumer base when it comes to cosmetics.
Data from Clinical Trial Stage 1a
The next two applications could prove to become mass money makers for HSTO.
HST 003 Joint Cartilage
HSTO is currently seeking approval to move to the clinical trial stage. If approved HST 003 would potentially be the only product that regenerated hyaline cartilage therefore improving functionality, mobility, and reduces inflammation. This is huge if it comes to fruition. So much so, that the DOD granted a 2 million dollar grant to HSTO in September of 2020. There is a current market of 1 billion annually for intra-articular in
... keep reading on reddit ➡
Nothing, he was gladiator.
Or would that be too forward thinking?
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
