https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120413/

Sorry, last one! I hope postings aren't duplicates.

https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0008225

Excellent article/study on really great alternatives to destroy scabies.

2 top options- Tea Tree oil and Clove oil.

I'm still scabies free- I switched over to tea tree oil and coconut oil 2 x a day. Morning and night application. Hope everyone is getting better!

https://parasitesandvectors.biomedcentral.com/articles/10.1186/s13071-016-1889-3

Depends on the hosts immune response of T helper cells.

Why some people can find it easier to get rid of scabies vs why some others struggle.

People whose immune system mounts a Th1 based intereferon-g response results in mite population control, and they are usually less than 10-15 mites on the entire body

For the others whose body mounts a Th2 based IgE response, mite population is very difficult to control (almost resistant) continues to grow unabated and can lead to crusted scabies.

So this is the reason why there are mixed responses on this sub. Why some people struggle endlessly whereas others think few applications of std treatment is all it takes.

From : (a recent source but there are few other studies too that state the Th2 IgE vs Th1 IL-10 responses) https://www.gaetanoscanni.it/data/_uploaded/media/ARTICOLI/Scabbia%20Miti/Scabies%20Myths%20to%20dispel%202021%20Book.pdf

The genetic predisposition for susceptibility or resistance to Sarcoptes scabiei var. hominis infestation has been hypothesized to be correlated with the dominance of an IgE-driven Th2 response in crusted scabies or an interferon-g-dominated Th1 response that induces a mite control

edit : here's one more comprehensive study : (58% of crusted scabies patients had immune system compromise but a huge 42% had no predisposition. however, the correlation to develop a Th2 response leads to crusted scabies in these)

https://d1wqtxts1xzle7.cloudfront.net/49863709/j.jinf.2004.08.03320161025-2847-1cr7aal-with-cover-page-v2.pdf

Eosinophilia and elevated IgE levels occurred in 58% and 96% of patients, respectively, with median IgE levels 17 times the upper limit of normal. Seventeen percent had a history of leprosy but 42% had no identifiable risk factors; a tendency to mount a Th2 response may underlie the apparent pre-disposition to develop crusted scabies.

Edit 2 : I wish moderators make this a sticky thread.

Edit 3 : another study on this with a possibility of vaccine based on immune responses

[https://www.cambridge.org/core/journals/parasitology/article/abs/vaccine-against-scabies-necessity-and-possibility/1AE14D59954BDE5096AFB83A28085D7A#article](https://www.cambridge.org/core/journals/parasitology/ar

An itchy skin condition that can be caused by a burrowing mite called Sarcoptes scabiei is known as scabies. You would die to scratch at the area where the mite burrows. And the intense itching will take place at night. Because of its contagious nature scabies spread quickly through physical contact. As scabies is contagious the whole family of an infected person is suggested. There is no big issue in treating scabies because its treatment is available in the market easily. But still, there will be some itching after some weeks of treatment.

To Read More : (https://infoidiots.com/scabies-treatment-pictures-symptoms-and-causes/)

I don’t know how comprehensive it is, but the tables look pretty good.

https://www.researchgate.net/profile/Aditya-Shiven/publication/348863513_Natural_and_synthetic_agents_for_the_treatment_of_Sarcoptes_scabiei_a_review/links/6013988a299bf1b33e30d7b5/Natural-and-synthetic-agents-for-the-treatment-of-Sarcoptes-scabiei-a-review.pdf

Исследователи решили выяснить, как повлиял локдаун 2020 года на распространённость педикулёза в Буэнос-Айресе. Как выяснилось, до пандемии вши встречались почти у 70% детей (какой кошмар!), а с введением карантинных мер эта цифра упала до 44%. Но не всё так радужно.

Человеческая головная вошь, полная свежевыпитой крови.

Вши играли настолько важную роль в эволюции человека, что существует даже отдельная «паразитарная» гипотеза: наших шестиногих спутников обвиняют в исчезновении шерсти у предков человека. Кроме того, по генетике вшей датируют появление одежды: линии головной и платяной вшей разделились 170 тыс. лет назад. Полагают, это могло произойти лишь тогда, когда лишившиеся шерсти древние люди стали надевать на себя искусственные утеплители, создав для паразитов новую экологическую нишу…

Вши шагают вместе с нами по эволюционной дорожке от начала времен! Кстати, в отличие от блох, которые, вроде бы, присоседились к людям относительно недавно.

Ну, радоваться тут нечему. Хотя платяная вошь встречается сейчас, вроде бы, не так часто — по крайней мере, в цивилизованных странах — педикулёз головы остаётся одним из самых распространённых детских паразитарных заболеваний в мире.

Pediculus humanus capitis питается кровью и всю жизнь живёт на голове своего хозяина. Помимо доставляемых неудобств, головные вши могут переносить инфекционные болезни, хотя в этом качестве и уступают платяным. Показано, что из-за дискомфорта у «завшивленных» детей меняется поведение и даже падает успеваемость в школе.

Ключевой момент — как происходит заражение. Для этого нужен прямой контакт «голова к голове», то есть социальное взаимодействие между одноклассниками в школе, соседскими детишками во дворе, а дома — между членами семьи. По статистике, вши чаще всего встречаются у детей от 3 до 14 лет, причём у девочек в 2—4 раза чаще, чем у мальчиков — отчасти из-за длинных волос, отчасти, вероятно, из-за отличий в поведении — как пишут в статье, из-за большей склонности играть в игры, требующие контакта головами.

И в XXI веке педикулёз представляет серьёзную проблему. Например, в Новом Свете распространённость вшей среди детей колеблется от 2 до 80%, особенно в странах Южной Америки. Очень страдают от педикулёза школьники Аргентины. Согласно одному из исследований с участием 1856 детей из школ Буэнос-Айреса, 30% детей этого города о

https://pubmed.ncbi.nlm.nih.gov/34388422/

First evidence of the activity of an entomopathogenic fungus against the eggs of Sarcoptes scabiei

TDRL:

mycoinsecticides and mycoacaricides such as Beauveria bassiana work to control pests on plants and in the lab, takes a few days to kick in, but hasn't been studied on mammals yet...

- I haven't found any evidence on mammals, so I wouldn't try it, but thought it was an interesting potentially new treatment in the future. (There are articles of people getting fungal keritis from this fungus so might just get a fungal infection in addition to the scabies T.T)

• Thyroid values ​​(T4 and TSH) normal.
• No significant abnormal changes are observed in the X-rays of the chest cavity.
• A full-body CT scan showed no visible tumors, but the contrast agent was significantly more intense on the muscles. The neurologist suspects peripheral nervous system disease, they think of infections like leishmania.
• Leishmaniasis and Sarcoptes scabiei test from February were negative.
• Two separate blood tests two weeks apart (with and without prednisone) show hypercalcemia and non-regenerative anemia. ALT slightly elevated.
• Ultrasound of the abdominal area showed nothing abnormal.
• The first course of Prednisone helped with skin symptoms in November, then the second course did not seem to help, now he is off Prednisone so that they can take some other tests.
• The neurologist said that it does not match Myasthenia Gravis.
• They are waiting on an ultrasound of the thyroid and a blood test of PTH and PTH-RP. Other tests they are taking today were electrogram (or something like that) of the muscles and muscle biopsies.

The vet told me to expect the worst, but if I would expect him to die tonight then I would take him home already because I don't want him to die alone. She also said that if his lungs or heart were to stop, at the ICU they can resuscitate him and we could not do that at home.

I would like to know which muscle disea

Acinetobacter baumannii Acinetobacter infections Actinomyces israelii, Actinomyces gerencseriae and Propionibacterium propionicus Actinomycosis Trypanosoma brucei African sleeping sickness (African trypanosomiasis) HIV (Human immunodeficiency virus) AIDS (acquired immunodeficiency syndrome) Entamoeba histolytica Amoebiasis Anaplasma species Anaplasmosis Angiostrongylus Angiostrongyliasis Anisakis Anisakiasis Bacillus anthracis Anthrax Arcanobacterium haemolyticum Arcanobacterium haemolyticum infection Junin virus Argentine hemorrhagic fever Ascaris lumbricoides Ascariasis Aspergillus species Aspergillosis Astroviridae species Astrovirus infection Babesia species Babesiosis Bacillus cereus Bacillus cereus infection multiple bacteria Bacterial meningitis multiple bacteria Bacterial pneumonia List of bacterial vaginosis microbiota Bacterial vaginosis Bacteroides species Bacteroides infection Balantidium coli Balantidiasis Bartonella Bartonellosis Baylisascaris species Baylisascaris infection BK virus BK virus infection Piedraia hortae Black piedra Blastocystis species Blastocystosis Blastomyces dermatitidis Blastomycosis Machupo virus Bolivian hemorrhagic fever Clostridium botulinum; Note: Botulism is not an infection by Clostridium botulinum but caused by the intake of botulinum toxin. Botulism (and Infant botulism) Sabiá virus Brazilian hemorrhagic fever Brucella species Brucellosis Yersinia pestis Bubonic plague usually Burkholderia cepacia and other Burkholderia species Burkholderia infection Mycobacterium ulcerans Buruli ulcer Caliciviridae species Calicivirus infection (Norovirus and Sapovirus) Campylobacter species Campylobacteriosis usually Candida albicans and other Candida species Candidiasis (Moniliasis; Thrush) Intestinal disease by Capillaria philippinensis, hepatic disease by Capillaria hepatica and pulmonary disease by Capillaria aerophila Capillariasis Bartonella bacilliformis Carrion's disease Bartonella henselae Cat-scratch disease usually Group A Streptococcus and Staphylococcus Cellulitis Trypanosoma cruzi Chagas disease (American trypanosomiasis) Haemophilus ducreyi Chancroid Varicella zoster virus (VZV) Chickenpox Alphavirus Chikungunya Chlamydia trachomatis Chlamydia Chlamydophila pneumoniae Chlamydophila pneumoniae infection (Taiwan acute respiratory agent or TWAR) Vibrio cholerae Cholera usually Fonsecaea pedrosoi Chromoblastomycosis Batrachochytrium dendrabatidis Chytridiomycosis Clonorchis sinensis Clonorchiasis Clostridium diff

See here:

https://www.reddit.com/r/confession/comments/23bri9/scabies_hell/

The post:

schmel5126 years ago

Okay John431, I'm going to offer up a solution.. it's a bit controversial but here goes.. at one stage we had a lice infestation run through the children in the family - my sister's hairdresser suggested as a solution that we use a flea and parasite spot treatment designed for dogs and cats on the children... they had used this on their own children and many clients with no ill effect, only to the effect that the lice were eradicated. What makes it so successful is that you don't need to continuously launder the bedding... the treatment will get through the bedding but I would recommend that you continue to do so daily. Of course it is pretty potent stuff and you don't use a whole tube of the spot treatment on yourself, just squeeze a couple of drops on to a cotton bud enough to wet it and spread it over the skin on the crown of the head for head lice.. for scabies perhaps dab the cotton bud at the most infected sites. This preparation is a Imidacloprid, Moxidectin preparation.. where I live it is called Advocate or Advantage. I would first do a spot test on the back your neck and wait a half an hour for any reaction and if you have no skin or other reaction then I'd give it a go. I have used it on myself when I was pregnant and I'm still alive and my baby is as healthy as anything. That said, there are no human studies, and no human longitudinal studies to assess a) its efficacy in humans or b) any side effects in humans, but there are animal studies which state efficacy in dogs with Sarcoptes scabiei (exactly the same mite found on humans) and complete eradication of the mite after day 22 of the treatment. The dogs were treated twice, 4 weeks apart. Good luck OP... this is nothing to be ashamed of. Keep us posted of your progress.

3

Does anyone have any experience? I wonder if this is worthwhile?

Hey all,

Ive struggled with dandruff all my life, and recently (last 5 years) with seb derm. I wanted to share some of the information I learned in an immunology class at Stanford that really helped my understanding of whats going on. This is a moderate amount of science and maybe without a background on it, it might be difficult to follow. Though, if you have questions please leave a comment. Im going to wrap the science into a conclusion that supports the hypothesis that mushroom consumption can greatly impact your skin conditions.

Its important to mention that Malassezia microbes vary in their pathogenicity based on which type and where. For most people these organisms are commensal (This genus of microbes/fungi accounts for over 90% of the organisms on your skin).

Though, in some people(3-5%) of the population, these microbes are pathogenic. This is especially true for immunocompromised people. So, Alzheimer’s, Parkinson’s, HIV/AIDs, stroke and TBI survivors... (to name a few common ones)

As lipophilic microbes, they’re going to cluster in your sebaceous glands. Though, this is not the interesting part. Typically, fungi have incredible means to evade the immune system and produce superficial and systemic infections. This may explain why your seb derm literally never goes away.

Malassezia produces a biofilm through cell surface hydrophobicity and precludes the yeast cell from being phagocytosed. This is a complicated battle between your immune system and the bacterias that live on you. A neurotypical human with a fully functioning immune system is usually capable of defending the integument and this conversation is of no concern.

(This next part is extremely trunchated) The immune system deals with microbial overgrowth with direct cellular contact (nk cells/macrophages/etc) where these cells display dectin 2/mincle proteins as well as other members of the c-lectin family. These proteins are associated with lymphocyte activity and induce the adaptive immune system.

Consequently, our immune system interacts with these pathogens through indirect cellular contact as well (cytokines/interleukins)

Interleukins, stimulate the proliferation of T cells and lymphokine activated killer cells. Some closely associated Interleukins (IL1,2,4,13,14,15,33) Essentially these signaling molecules regulate the inflammatory response and recruit the immune cells that are responsible for maintaining the integrity of your skin and fighting pathogens.

For someone

The NCBI posted a study by the NIH which to assessed the potential efficacy of ten essential oils against Sarcoptes scabiei.

They conducted skin and fumigation studies. I'm sharing the skin contact studies only, but here's a link to the study. page.  https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5120413/

"Using contact bioassays, 1% clove and palmarosa oil killed all the mites within 20 and 50min, respectively. The oils efficacy order was: clove > palmarosa > geranium > tea tree > lavender > manuka > bitter orange > eucalyptus > Japanese cedar.

Conclusion: Essential oils, especially tea tree, clove, palmarosa, and eucalyptus oils, are potential complementary or alternative products to treat S. scabiei infections in humans or animals, as well as to control the mites in the environment."

Note: Vaseline is yellow, soft paraffin.

I see they didn't test Neem oil, which many people have found to be really helpful.

It's refreshing to see they tested this. That lab must have smelled like a Wiccan store threw up in a Bath & Body Works!

Do your worst!

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂

Hi everyone! I'm new in this community, however I already found a lot of cool stuff here, that helped me in my studying for USMLE step1. So I would like also contribute to this community and share some stuff. I know it is not so significant, but may be it could help someone.

I gathered them mostly from FA

Tick-borne infections:

1. Lyme disease - Borrelia burgdorferi - Ixodes tick
2. Anaplasmosis - Anaplasma - Ixodes tick
3. Babesiosis - Ixodes tick
4. Ehrlichiosis - Ehrlichia chafeensis - Amblyomma - Lone Star tick
5. Tularemia - F tularensis - Tick (+rabbits, deer flies)
6. Rocky Mountain Spotted fever - Rickettsia rickettsii - Dermacentor - Dog tick
7. Colorado tick fever - Coltivirus (Reovirus) - wood tick bite (Dermacentor andersoni) - Lives in rodents (squirrels,chipmunks) in Rocky Mountains
8. Crimean-Congo hemorhhagic fever - tick-borne

Mite-borne infections:

1. Scabies - Sarcoptes scabiei

Lice-borne infections:

1. Relapsing fever - Borrelia reccurentis - Human Body Louse
2. Epidemic typhus - Rickettsia prowazekii - Human body louse
3. Trench fever - Bartonella quintana - Human body louse
4. Pediculosis - Pediculus humanus
5. Pubic lice - Phthirus pubis

Flea-borne infections:

1. Endemic (Murine) typhi - Rickettsia typhi - flea
2. Plague - Y pestis - Fleas - reservoirs are rats and prairie dogs in USA

Fly-borne infections:

1. Tularemia - F tularensis - Deer flies (Also more Ticks, Rabbits)
2. African sleeping disease - Tsetse fly - PAINFUL bite
3. Leischmaniasis - Plebotomus Sandfly (actually it is a mosquitto)
4. Onchocerca volvulus - Female black fly
5. Loa Loa - Deer fly, horse fly, mango fly

Bug-borne infections:

1. Kissing bug - Triatomite → PAINLESS bite →Trymanosoma cruzi → Chagas disease

Mosquitto-borne infection:

1. Female Anopheles - Malaria
2. Female Mosquitto - Wuchereria bancrofti
3. Aedes mosquito - Yellow fever, Dengue fever, St.Louis encephalitis, West Nile virus, Chikungunya
4. Culex mosquito - West-Nile virus

Urine from mice (rodents) → Hantavirus and Leptospirosis

Urine from rats → Lassa fever encephalitis

Urine of rats and mice - LCMV

+ Some cat stuff:

1. Cat Scratch - Bartonella henselae
2. Cat Bite - Pasteurella multocida (Dog as well) → Cellulitis and Osteomyelitis
3. Cat Feces - Toxoplasmosis
4. Toxocara cati - Visceral larva migrans

May be I made mistakes, so if you notice please correct me.

They’re on standbi

Pilot on me!!

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

I won't be doing that today!