ELI5: Why is Abreva the only cold sore treatment with the active ingredient that actually heals cold sores (Docosanol) while every other cold sore "treatment" just has numbing ingredients like menthol?

I have been getting cold sores regularly since I was very young. The only topical treatment available at drugstores that is FDA approved to heal them is Abreva, and it is ridiculously expensive (I just bought a .07 oz tube for $21.99). It has Docosanol in it, so I have always looked for alternatives that also have that ingredient. Every other cold sore treatment, even the store brand Abreva, does not have this ingredient. Instead, they aim to just treat the pain and discomfort. Why are there no other treatments that actually help the healing instead of just masking the discomfort? Why do no other treatments have Docosanol, and why is Abreva so expensive? ELI5!

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πŸ‘€︎ u/calicocatie
πŸ“…︎ Jun 03 2014
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SERIOUS: This subreddit needs to understand what a "dad joke" really means.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

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πŸ‘€︎ u/anywhereiroa
πŸ“…︎ Jan 15 2022
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Blind Girl Here. Give Me Your Best Blind Jokes!

Do your worst!

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πŸ‘€︎ u/Leckzsluthor
πŸ“…︎ Jan 02 2022
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This subreddit is 10 years old now.

I'm surprised it hasn't decade.

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πŸ‘€︎ u/frexyincdude
πŸ“…︎ Jan 14 2022
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Dropped my best ever dad joke & no one was around to hear it

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies πŸ˜‚

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πŸ‘€︎ u/Vegetable-Acadia
πŸ“…︎ Jan 11 2022
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What starts with a W and ends with a T

It really does, I swear!

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πŸ‘€︎ u/PsychedeIic_Sheep
πŸ“…︎ Jan 13 2022
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Why did Karen press Ctrl+Shift+Delete?

Because she wanted to see the task manager.

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πŸ‘€︎ u/Eoussama
πŸ“…︎ Jan 17 2022
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I’m a rare case and the β€œspecialist” I saw is an idiot

Check my other posts for more info but long story short I have had ghsv2 since 2013. Outbreaks now are infrequent and don’t produce lesions. I reached a nice harmony with it.

Then last year I erupted in herpetic rash all over my upper body, face, and hands, and what seems to be like some mild herpetic folliculitis in some areas. This is occurring on both sides of my body, which would make shingles rare (though not impossible).

I thought maybe I contracted hsv1 (which I have been negative for in the past) and was having a primary infection type reaction (it was so bad at first)....but several months after the worst outbreak in these areas I still don’t have antibodies for hsv1, and the outbreaks in these areas keep recurring, though never as bad as the first time. They respond rapidly to Zovirax.

This to me would indicate that it’s a rare case of ghsv2 manifesting outside of its typical zone, or a rare case of shingles since it is manifesting on both sides of the body.

I saw an infectious disease specialist and she was completely uninterested in exploring my case, since the practical answer no matter what is just less stress and more valtrex. She also had never heard of abreva/docosanol or herpetic folliculitis (she tried to tell me folliculitis can only be bacterial, when there are fungal and viral versions too).

It sucks having to just embrace a mystery of why this is happening. I would like to know for sure for sure what type of herpes is manifesting in these areas, but I would have to get a legitimate biopsy...because my symptoms are typically limited to β€œdry” lesions that can’t be swabbed. I’ve gotten a water blister twice but couldn’t get to a doctor in time. I may got off my antivirals for a while just to see if I can get some symptoms that might be easier to test...

I wonder if getting the Covid vaccine could have something to do with this. It has been shown to cause a reactivaciΓ³n of varicella in some people. I had that terrible outbreak with herpetic rash all over my torso, ache in my arms, whitlow on finger, not long after getting the J&J

Herpes or shingles it sucks to have so many new symptoms now in new places

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πŸ‘€︎ u/Rastagoldilox
πŸ“…︎ Jan 11 2022
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What is a a bisexual person doing when they’re not dating anybody?

They’re on standbi

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πŸ‘€︎ u/Toby-the-Cactus
πŸ“…︎ Jan 12 2022
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Geddit? No? Only me?
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πŸ‘€︎ u/shampy311
πŸ“…︎ Dec 28 2021
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I wanna hear your best airplane puns.

Pilot on me!!

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πŸ‘€︎ u/Paulie_Felice
πŸ“…︎ Jan 07 2022
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E or ß?
πŸ‘︎ 9k
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πŸ‘€︎ u/Amazekam
πŸ“…︎ Jan 03 2022
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What did Spartacus say when the lion ate his wife?

Nothing, he was gladiator.

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πŸ‘€︎ u/rj104
πŸ“…︎ Jan 15 2022
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Pun intended.
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πŸ‘€︎ u/Sharmaji1301
πŸ“…︎ Jan 15 2022
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No spoilers
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πŸ‘€︎ u/Onfour
πŸ“…︎ Jan 06 2022
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Covid problems
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πŸ‘€︎ u/theincrediblebou
πŸ“…︎ Jan 12 2022
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These aren't dad jokes...

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

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πŸ‘€︎ u/Lance986
πŸ“…︎ Dec 15 2021
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I had a vasectomy because I didn’t want any kids.

When I got home, they were still there.

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πŸ‘€︎ u/demotrek
πŸ“…︎ Jan 13 2022
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What did 0 say to 8 ?

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

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πŸ‘€︎ u/designjeevan
πŸ“…︎ Jan 03 2022
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Spi__
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πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 11 2022
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I dislike karma whores who make posts that imply it's their cake day, simply for upvotes.

I won't be doing that today!

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πŸ‘€︎ u/djcarves
πŸ“…︎ Dec 27 2021
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The Ancient Romans II
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Dec 29 2021
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I'd like to dedicate this joke to my wisdom teeth.

[Removed]

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πŸ‘€︎ u/ThoughtPumP
πŸ“…︎ Jan 14 2022
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Where do you find a cow with no legs?

Where ever you left it πŸ€·β€β™€οΈπŸ€­

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πŸ‘€︎ u/kitkatty0309
πŸ“…︎ Jan 16 2022
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I did it, I finally did it. After 4 years and 92 days I went from being a father, to a dad.

This morning, my 4 year old daughter.

Daughter: I'm hungry

Me: nerves building, smile widening

Me: Hi hungry, I'm dad.

She had no idea what was going on but I finally did it.

Thank you all for listening.

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πŸ‘€︎ u/Sk2ec
πŸ“…︎ Jan 01 2022
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It this sub dead?

There hasn't been a post all year!

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πŸ‘€︎ u/TheTreelo
πŸ“…︎ Jan 01 2022
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How do you stop Canadian bacon from curling in your frying pan?

You take away their little brooms

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πŸ‘€︎ u/Majorpain2006
πŸ“…︎ Jan 09 2022
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School Was Clothed
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πŸ‘€︎ u/Kennydoe
πŸ“…︎ Jan 08 2022
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Remember that joke I told you about the chiropractor?

It was about a weak back.

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πŸ‘€︎ u/tanglwyst
πŸ“…︎ Jan 16 2022
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Naan-negotiable
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πŸ‘€︎ u/sjmaeff
πŸ“…︎ Jan 16 2022
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Letting loose with these puns
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πŸ“…︎ Jan 13 2022
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Couch potato
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πŸ“…︎ Dec 31 2021
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Baka!
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πŸ‘€︎ u/ridi86
πŸ“…︎ Jan 09 2022
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All dad jokes are bad and here’s why

Why

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πŸ‘€︎ u/LordCinko
πŸ“…︎ Jan 13 2022
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concrete πŸ—Ώ
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πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 07 2022
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My name is ABCDEFGHIJKMNOPQRSTUVWXYZ

It’s pronounced β€œNoel.”

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πŸ‘€︎ u/beef_fried_rice
πŸ“…︎ Dec 25 2021
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Why are people so surprised and angry about Djokovic being an anti-vaxxer?

After all his first name is No-vac

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πŸ‘€︎ u/hangryman23
πŸ“…︎ Jan 06 2022
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If Korean pop is shortened to Kpop and Korean Drama is Kdrama...

What, then, is Chinese rap?

Edit:

Notable mentions from the comments:

  • Spanish/Swedish/Swiss/Serbian hits

  • French/Finnish art

  • Country/Canadian rap

  • Chinese/Country/Canadian rock

  • Turkish/Tunisian/Taiwanese rap

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πŸ‘€︎ u/hootanahalf
πŸ“…︎ Jan 09 2022
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Knowledgeable man
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πŸ‘€︎ u/elisioth4739
πŸ“…︎ Jan 16 2022
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That’s Michelle
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πŸ‘€︎ u/FLEXSEALBREAKER
πŸ“…︎ Jan 10 2022
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Is this sub still active?

There hasn't been a single post this year!

(Happy 2022 from New Zealand)

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πŸ‘€︎ u/DonStimpo
πŸ“…︎ Dec 31 2021
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What did the ocean say to the beach?

Nothing, it just waved

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πŸ‘€︎ u/hackerboi1198
πŸ“…︎ Jan 13 2022
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is Isn't
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Jan 11 2022
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My 9 year old son just asked me to pretend I was a police officer arresting him for downloading the entire Wikipedia. Me: Young man, you're under arrest for downloading the entire Wikipedia!

Him: I can explain everything!

(It's his best joke yet I think)

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πŸ‘€︎ u/MrPJ2020
πŸ“…︎ Jan 14 2022
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@u/mordrathe - remix
πŸ‘︎ 2k
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πŸ‘€︎ u/SpydrRydr
πŸ“…︎ Jan 12 2022
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What do you call a guy with no arms and no legs in a hot tub?

Bob

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πŸ‘€︎ u/4fuchssake
πŸ“…︎ Jan 05 2022
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What is the scariest tree?

BamBOO!

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πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
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I named my dog "5 miles."

So that I could frequently say, "I am going to walk 5 miles now."

Edit: My most popular post on Reddit! πŸ˜€ Thank you for the awards.

πŸ‘︎ 3k
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πŸ‘€︎ u/javacafe
πŸ“…︎ Jan 10 2022
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