Peptide profiling of Internet-obtained Cerebrolysin using high performance liquid chromatography - electrospray ionization ion trap and ultra high performance liquid chromatography - ion mobility - quadrupole time of flight mass spectrometry (2015) ncbi.nlm.nih.gov/pubmed/2…
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πŸ‘€︎ u/FW900
πŸ“…︎ Jun 10 2015
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New long term metabolite in human urine for metenolone misuse by liquid chromatography quadrupole time-of-flight mass spectrometry (2016) sciencedirect.com/science…
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πŸ‘€︎ u/dustofoblivion123
πŸ“…︎ Nov 30 2015
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[ASAP] Evaluating Spatiotemporal Dynamics of Phosphorylation of RNA Polymerase II Carboxy-Terminal Domain by Ultraviolet Photodissociation Mass Spectrometry

Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c03321

Edwin E. Escobar, Mukesh Kumar Venkat Ramani, Yan Zhang, and Jennifer S. Brodbelt

https://ift.tt/3fU6EVG

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πŸ‘€︎ u/TomisMeMyselfandI
πŸ“…︎ May 31 2021
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Characterisation of the transcriptome and proteome of SARS-CoV-2 using direct RNA sequencing and tandem mass spectrometry reveals evidence for a cell passage induced in-frame deletion in the spike glycoprotein that removes the furin-like cleavage site biorxiv.org/content/10.11…
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πŸ‘€︎ u/sanxiyn
πŸ“…︎ Mar 29 2020
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Simultaneous Quantification of Ten Key Kratom Alkaloids in Mitragyna speciosa Leaf Extracts and Commercial Products by Ultra-Performance Liquid Chromatography - Tandem Mass Spectrometry

Below is a table from the paper named in the subject. The paper outlines a new process that was developed by Bonnie Avery McCurdy (Dr. McCurdy's wife) and the team at U of F before she died earlier this year. The paper itself is still only available after paying for it, so it would be unethical for me to post it here. However, I believe it should be ok to post the table. (If I'm wrong, let me know.) Here's a link to the abstract. https://onlinelibrary.wiley.com/doi/abs/10.1002/dta.2604

The top three items are extracts analyzed at the lab (lyophilized tea is freeze-dried kratom tea) but the rest are commercial batches of kratom. BLR is a Red Bali, MDG is a green maeng da, then Plantation Red Maeng Da.

The gold and the last two batches all contain extract. The gold appeared to contain the alkaloid rich fraction from kratom. The other two likely contained and alcohol extraction. It's unclear whether the white vein contains extract or not. Given the company and the amount of mitragynine, it's likely that it has some. The Black Jaguar says it's white maeng da with red maeng da extract. The Red Label may be pure extract from the ad copy, but who knows. It's so hard to tell with this type of product. Some companies refer to powdered leaves as kratom extract. Others add extract but don't mention it.

To make the tea, dried leaves were boiled for 20 minutes. They noted, as can be seen below, that the tea contained much less mitragynine than the powders and capsules.

Obviously, this is a very small sampling, but it gives an idea of what researchers are seeing as they analyze commercial batches of kratom. The paper mentions that other products are being analyzed, so hopefully, a future paper may give a broader overview.

https://i.redd.it/d5v74ykl90i31.png

Edit: As u/enigmaticpeon pointed out, the strain names used in the study are just the names the vendors put on the kratom. It shouldn't be construed as validating the existence of strains. Dr. McCurdy has said that strains seem to just be a marketing device in the West and at least one vendor whose kratom was analyzed agreed.

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πŸ‘€︎ u/AzulKat
πŸ“…︎ Aug 22 2019
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Increasing Compound Identification Rates in Untargeted Lipidomics Research with Liquid Chromatography Drift Time-Ion Mobility Mass Spectrometry inpst.net/increasing-comp…
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πŸ‘€︎ u/AG_Atanasov
πŸ“…︎ Feb 06 2019
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Using mass spectrometry imaging, scientists describe new molecules that form direct link between gut microbiome and brain function (Mar 2020, mice) Microbiome-derived carnitine mimics as previously unknown mediators of gut-brain axis communication. medicalxpress.com/news/20…
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πŸ‘€︎ u/MaximilianKohler
πŸ“…︎ Mar 16 2020
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Dr. Joanna Albala et al. - Improving Human Health One Atom at a Time - Biomedical Accelerator Mass Spectrometry youtube.com/watch?v=DOXlr…
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πŸ‘€︎ u/gorillaz0e
πŸ“…︎ Jul 31 2018
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Geochemical Investigation of Tar Balls Collected in a Brazilian Beach Using Biomarkers, Ni/V, Ξ΄13C Ratios and Ultra-High Resolution FT-ICR Mass Spectrometry scielo.br/scielo.php?scri…
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πŸ‘€︎ u/GeochemistLLM
πŸ“…︎ Apr 19 2020
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Research: Top-down mass spectrometry analysis of an intact adult mosquito imgur.com/Qsy3RFW
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πŸ‘€︎ u/Wakewalking
πŸ“…︎ Feb 13 2019
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Using mass spectrometry data, scientists find that large, carbon-rich organic molecules are ejected from cracks in the icy surface of Saturn’s moon Enceladus. They think chemical reactions between the moon’s rocky core and warm water from its subsurface ocean are linked to these complex molecules. swri.org/press-release/ev…
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πŸ‘€︎ u/drewiepoodle
πŸ“…︎ Jun 27 2018
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[ASAP] Molecular Mechanism of ISC Iron–Sulfur Cluster Biogenesis Revealed by High-Resolution Native Mass Spectrometry

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b11454

https://ift.tt/3da0kHp

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πŸ‘€︎ u/TomisMeMyselfandI
πŸ“…︎ Mar 18 2020
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The Value of Expanding Mass Spectrometry Use : December 2018 medlabmag.com/article/153…
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πŸ‘€︎ u/blunden25
πŸ“…︎ Dec 21 2018
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Nude Nicotine = Heisenberg of Vaping. Included in my order was a mass spectrometry reading of the components used in my juice.
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πŸ‘€︎ u/dead2you
πŸ“…︎ Sep 26 2014
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