A list of puns related to "Pemphigoid"
So Iβm kind of at my witβs end here and I just need some positive reassurance or something. Currently 40+3 FTM.
About a week ago I developed a rash on my stomach that seemed to be PUPPPS. It was itchy and miserable, but manageable because it was only on my stomach. I had an OB appointment on Wednesday, and at this point the rash was only spreading mildly to my hips, thighs and hands. She recommended Benadryl if I was losing sleep over it.
The next 2 days the rash explodes to pretty much my entire body below my neck. Huge red and purple welts all over, and itβs spreading FAST. Itβs quickly climbing up my back, down my legs, into my armpits. Into my BUTTCRACK?? The rash on my hands, arms and feet has begun BLISTERING and is appearing on my palms and even the bottoms of my feet and between my toes and fingers. I can barely get up and walk around because itβs on the bottoms of my frigging toes. It looks exactly like a poison ivy rash on my hands and feet but everywhere else is just huge red and purple lumps.
It doesnβt seem like just PUPPPS and more of a mix between PUPPPS and Gestational Pemphigoid. It feels absolutely torturous. Constant itching and burning all over my entire body. Benadryl doesnβt help. Ointments donβt help. Ice packs donβt help. Pine tar soap, oatmeal, aloeβ¦nothing helps. Iβm seriously miserable.
I went to the ER today and had a whole slew of nurses checked me out and none of them knew what it was. Most of them said they think itβs an allergic reaction to something but they arenβt really sure. They ran a bunch of tests and they all came back normal. Two of them suggested induction if it is in fact PUPPPS/GP. I donβt know anything about induction and now Iβm even more terrified. I ended up scheduling an induction for tomorrow night because I just canβt take this anymore.
Iβm just so super scared and feeling helpless and alone. I feel selfish for opting for induction instead of just toughing it out a little longerβ¦but I canβt take this rash anymore and it gets worse every single day. None of this was part of my plan, which I know sounds ridiculous because you canβt really expect everything to go perfectlyβ¦but I was really looking forward to natural, spontaneous labor. I donβt know what to expect from induction but it sounds so stressful and scary.
pictures for the curious, NSFW
https://imgur.com/a/KfDAtd2
Hello smart and kind people!
From my understanding, the difference between Polymorphic eruption of pregnancy and Pemphigoid gestationis is:
Polymorphic eruption of pregnancy: urticarial papules and plaques
Pemphigoid gestationis: blistering rash
Is that all?
Thanks!
Case History:
So around October of 2017 I was on a work term in a neighbouring city. I started feeling terrible itching in the evenings as I lay in bed trying to sleep. Mainly around my shins, wrists, ankles, inner thighs and upper arms. To the point it was becoming unbearable. I talked to a pharmacist. Many times when I move to a new place I find I itch with different water so they suggested Benadryl. No help at all. I thought it might also be new laundry detergent. Tried calamine lotion which also didn't work.
Around this time I started taking melatonin and an iron supplement. Just thought I'd add that to be thorough.
Went to the small hospital in the town I was working and the doctor immediately diagnosed me with scabies. Terribly embarrassing as I had to tell the people who I were staying with. I did two treatments with Permethrin cream which did not help, in fact burned me terribly. By now the rash was starting to turn to blisters and my itching was not immediately where the blisters were, but I noticed in the areas where I did itch, blisters would eventually form in the same place in a day or two. This was mid-December and my work term was over so it was time to move back home. Not long after returning I went to the larger hospital which was much more thorough but by this time I looked like this:
Possible NSFW https://imgur.com/a/rqVsobf Bonus hospital gown for fashion purposes. Both arms and upper legs looked like this.
I was diagnosed with Bullous Pemphigoid and I was immediately put on 100mg of prednisone and saw a dermatologist the next week. The steroids worked amazingly well and the blisters healed rather quickly and my skin quickly healed. It now looks a just a little splotchy but I'm pretty much back to normal. As I weaned off the steroids I would get to around 20mg and the itching would return. My Derm doctor prescribed Cellcept (Mycophenolic acid 1000mg/daily) that I started around mid-July. I had no coverage for this drug and it was a bit pricey. I paid for 3 months but got no real relief and could not afford any more. I seemed to be stuck around 20mg/day of prednisone. The side effects from the Cellcept were rough. It seemed to cause a colitis flare-up. My Cellcept prescription ran out mid-October and I am again just on prednisone. Around the beginning of October I did feel good below 20mg/day of prednisone and managed to get down to 0mg but after 2 days the itching started again so I went back to 10mg/day. My Derm do
... keep reading on reddit β‘Mucous membrane pemphigoid is a group of rare and chronic autoimmune diseases which are characterized by blistering on the various mucous layers of the body. Mucous membranes of mouth, nose, throat, and eye are often affected by the mucous membrane pemphigoid. In June 2018, FDA approved Genentechβs rituxan, first treatment in more than 60 years for the treatment moderate to severe pemphigus vulgaris (PV).
The manufacturers in mucous membrane pemphigoid treatment market are focusing on the developing new and effective formulations. Being a rare disease, mucous membrane pemphigoid treatment market offers limited patients pool for the treatment and hence manufacturers are developing new formulation by keeping an eye on the overall potential economic return as well as development expenditure. The incidence of mucous membrane pemphigoid varies widely, for example, the incidence of mucous membrane pemphigoid U.K. is 1 in million population whereas in Germany and France the incidence is 2 in million population. Although the difference in the incidence does not look vast but considering it as a rare disease it varies widely.
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Mucous Membrane Pemphigoid Treatment Market: Drivers and Restraints
The average age of onset of mucous membrane pemphigoid is 60 years and hence the ageing population of the world expected to result in increased incidence of the disease driving the growth of the mucous membrane pemphigoid treatment market. The increasing availability of treatment option further expected to fuel the growth of the mucous membrane pemphigoid treatment market.
The increasing rate of diagnosis due to improving awareness about the disease further expected to enhance treatment-seeking rate, in turn, driving the growth of mucous membrane pemphigoid treatment market. Manufacturers in the mucous membrane pemphigoid treatment market are focusing on product approvals and launches in the developed as well as developing world which expected to increase their geographical product footprint fueling the growth of the mucous membrane pemphigoid treatment market.
Due to rare disease status, the disease, mucous membrane pemphigoid treatment options are given special status and exclusivity to encourage manufacturers to de
... keep reading on reddit β‘Sorry for the huge question -- I was wondering if anyone knew the reason why bullous pemphigoid alone does not have a positive nikolsky sign. Does anyone have any ideas? Thank you!
Six months ago, as a student nurse (waiting to take boards now), I was taking care of an elderly patient who happened to have bullous pemphigoid skin lesions on the arms, legs, and near the groin.
Patient was stable and speaking normally the first day. I came in the next morning and report said they had developed a hematoma in the back of their throat. Apparently unrelated to reason for admission, and I'm kicking myself because I can't remember what that was now, either.
I went in and assessed the patient and their speech was garbled and there definitely was something in the back of the throat, but didn't really look like a hematoma to me. Doctor was in and they made plans to take the patient to ICU in case the patient needed to be intubated.
Well, the patient started having bloody stool. Within the hour, it progressed from a little bit to the all of it being maroon-brown.
I left the room to confer with the primary nurse. I noticed their call light went off. I went in and there was about a golf ball sized bloody red mass sitting on the patient's chest. Patient was speaking and breathing normally at that point. I called for help and looked at the back of their throat again and it looked like most of whatever was in the back of their throat dislodged. The nurses who flooded in had no idea what the mass was and sent it up to ICU with the patient.
The patient was bleeding/coughing up blood by the time we took them to ICU. No one I asked, including my clinical instructor, had ever seen that happen or had any idea what it was.
So my question is, could this have been something related to bullous pemphigoid? Could some kind of mass like that have developed so quickly at the back of the throat? I tried reading up about it but it sounds like having them in the mouth/throat is rare.
This patient literally haunts me to this day. I wasn't able to figure out what happened to them or what exactly was going on. I don't know how much you could glean from the limited information I remember, but thought I would try anyway.
I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.
Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.
Do your worst!
I'm surprised it hasn't decade.
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies π
It really does, I swear!
Just wanted to vent a moment. (TW: Eating Disorder)
Tldr I developed a very rare autoimmune disorder where my immune system is attacking my skin. I have horrific looking painful and itchy lesions all over my feet. The moment I finished my steroid prescription, the flare-ups spread to my legs, arms and chest. I'm going to scar very badly. Doc made the diagnosis that it is bullous pemphigoid and put me back on the steroids (prednisolone).
Supposedly the cause of this is unknown but stress is a huge trigger. I have a really stressful deadline based job and I've started the year terribly by being behind on everything because I'm just too itchy and depressed to adequately function.
To top it off, this whole skin episode was made worse by the steroid use: it leaves me feeling constantly hungry and so I eat.
Mom observes what I eat, looking over my shoulder and giving me a judgemental look if I've taken seconds. I got comments like "just because the medication is making you hungry doesn't mean you need to give into it." + "if you're going to eat, I also hope you're planning on exercising," + "I think you should consider untucking your shirt," (to hide my "ponch" in a work ensemble) + "she has such nice skin but I'm concerned with her increased appetite which she ~blames~ on the medication"
All these various comments have come within the last few weeks. I was an anorexic teen and my mother knows this, so while I'm a health weight now, food and body image are things that definitely can make me spiral into an unhealthy mix of self-weighing, calorie counting, very reduced portions, skipping meals, moments of saying FUCK IT and binge-eating, you get the drift. I don't have much time or energy for exercise, not trying to make excuses it's just not something I was raised with so it's hard to get into healthy patterns when you don't even know where to begin.
Following my mum's comments about food combined with everything else, I think I've just had a kind of total mental breakdown. I'm not speaking to either parent and they're not talking to me and everyone is just okay with this.
My siblings don't live at home and don't think my parents behaviour is destructive or rather they've just accepted that's how they are. I get a lot of "it's up to you to decide how you want the actions of others to affect you," which is valid advice and all.
It's just. I'm here, all alone just about with a fun, new incurable illness. A bunch of looming deadlines and co-workers fr
... keep reading on reddit β‘Buenosdillas
Theyβre on standbi
Pilot on me!!
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
When I got home, they were still there.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
I won't be doing that today!
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