Given this:
Icariin enhances youth-like features by attenuating the declined gut microbiota in the aged mice
We previously reported the neuroprotective effects of icariin in rat cortical neurons. Here, we present a study on icariin's anti-aging effect in 24-month aged mice by treating them with a single daily dose of 100 mg/kg of icariin for 15 consecutive days. Icariin treatment improved motor coordination and learning skills while lowered oxidative stress biomarkers in the serum, brain, kidney, and liver of the aged mice. In addition, icariin improved the intestinal integrity of the aged mice by upregulating tight junction adhesion molecules and the Paneth and goblet cells, along with the reduction of iNOS and pro-inflammatory cytokines (IL-1Ξ², TNF-Ξ±, IL-2 and IL-6, and IL-12). Icariin treatments also significantly upregulated aging-related signaling molecules, Sirt 1, 3 & 6, Pot1Ξ±, BUB1b, FOXO1, Ep300, ANXA3, Calb1, SNAP25, and BDNF in old mice. Through gut microbiota (GM) analysis, we observed icariin-associated improvements in GM composition of aged mice by reinstating bacteria found in the young mice, while suppressing some bacteria found in the untreated old mice. To clarify whether icariin's anti-aging effect is rooted in the GM, we performed fecal microbiota transfer (FMT) from icariin-treated old mice to the old mice. FMT-recipients exhibited similar improvements in the rotarod score and age-related biomarkers as observed in the icariin-treated old mice.
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... keep reading on reddit β‘Iβm considering HGW for stronger erections. Iβve gone through so many of the old post in this sub and there are so many contradicting comments.
What is the difference between icariin and icariins?
What percentage of icariin/icariins should I look for? I read contradicting strengths.
Should someone be taking this everyday to build up in the system or only before sex?
Lastly, when choosing the supplement, do I look for one that uses just the leaves? Or both the leaves and stem?
Hi guys,
So I bought this HGW (10% icariins) as part of my boner stack recently from Amazon and had a question about dosing. Should this be taken everyday for the effects to manifest eventually or only when you want the effects to happened? I am looking for stronger wood before performance. My stack is as follows:
Triple boron complex (8mg with first meal)
HGW (taking 3 capsules every day now)
Maca capsules (6 capsules 2x1900mg)
Zinc/copper (45 mg before bed)
Citrulline malate (multiple dosing throughout the day)
Ginkgo 24% glycosides (2 capsules 120mg each)
Any suggestions will be greatly appreciated. Thanks!
