Tramadol Puns

I did around 300mg and it felt just like chewing a 40mg oxy, only it hit a lot slower. The body euphoria was even stronger and better then oxys, comparable to MDMA

It’s also like half the price of oxys which is nice.

Hello fellow psychonauts and researchers,

As most of you probably know, tramadol is kind of unique, far as opioids go. It posseses pretty standard action on the (recretionally) most important opioid receptor (MOR), but in addition to that, it also acts on the serotonin transporter (SERT), which gives it a kind of empathogenic edge and a few other effects traditionally more associated with the serotonin system than the opioid system, and also on the norepinephrine transporter (NET). It's principal metabolite, O-DSMT (or O-desmethyltramadol), loses the SERT action, but retains the NET action, which makes the two similar, but still distinct.

Far as I know, no tramadol analogues were ever made (or at least none became really known, it's possible I missed some studies containing some really really obscure ones), which is kind of surprising.

I am currently working on designing a theoretical structure for a compound which would posses both opioid and psychedelic action. The tramadol structure is the obvious one to try first, but I would like to have more options (ibogaine and its analogues don't really count, they are too promiscuous in terms of receptor action and their SERT affinity is pretty bad). So my question is: does anyone know of any serotonergic opioids that I might have missed in my literature search?

I still have some from a accident. Does this even go together figured I’d relax as much as possible for the holidays.

Tramadol is a synthetic opioid, which also has a snri properties. On a downer scale it is rated very low.

I tried Tramadol many times and honestly had a great time with it. The first hour of the effects are a boost (talkatativeness, motivation and a need to move), but after an hour (2nd hour) the effects switch into more of a downer-like drug.

You get sedated, mild mental euphoria and a medium body euphoria. You feel very warm and couchlocked is a must!! I love the 2nd hour. Tramadol's effects overall last for very long..., from my experience 4-6hours.

I'm really interested in hearing your opinion on this substance

Hello peeps,

I've just come back from the hospital and I'm pretty desperate at the moment.

I'm a 32-year-old female and have taken tramadol for about 12 years. It's made the difference between being exhausted, in pain and having a very hard time basically living. I've taken 150mg retard twice a day for most of the 12 years. Next to that, I'm taking amitryptilin daily, it helps with sleep mostly.

I really don't know how I would be able to live without it, but if I want to have a baby I'm going to have to. We don't want a misshapen baby, do we?

I've researched it all and went to different doctors. At the psychiatric mother - office I made a pre-conception appointment, and they suggested I could just stop once pregnant, so the urge would make it easier. They sent me to the pain clinic for other ideas.
Today I was at said pain clinic they had made a schedule for three weeks, so I'd be clean in three weeks (after 12y of high dose pain killers). No suggestions about replacement or detox meds or whatever. I told them I was scared about the pain coming back and she said the fear of pain is often mistaken for real pain. I would need distraction like taking chewing gum or a bath.

Chewing gum.

So my reason for coming here is the hope that there is someone in this subreddit who has had a similar experience.

Edit: I’m not pregnant yet, and won’t get pregnant until clean and detoxed enough. I’m well aware that could take a while.

- how did you manage to detox from tramadol? (without losing yourself / work / relationship / everything)?

- how bad is the pain after a while?

- is there anything I could do to make it easier?

- how do I survive through medication-free life & pregnancy?

- any other help because I'm feeling quite desperate.

----

extra:

Tramadol during pregnancy is bad. It influences proper development and I don't want that.

Amitryptiline is also not adviced during pregnancy, however it doesn't do any harm to the foetus, it's just that it's born a little addicted and needs some watching the first hours

I could also just go to a tropical place and detox the shit out of myself for 3 weeks, but I don't know if that's wise.

Been on tramadol for 6 years and it has taken over my life. I get my fill, finish in a week and a half and go through withdrawal. It’s like this every month. I have no self control and my provider has lowered the amount I get which has helped but I do the same thing. I know tramadol isn’t as strong as other opiates but withdrawal still feels like hell.

Ich habe schon Codein, ODSMT, Oxys, Tillis und mit Kratom Erfahrung. Trama habe ich aber noch nie genommen. Muss ich auf was achten? Bei den Oxys war es bei immer so das die erst gewirkt haben wenn ich was leichtes darauf gegessen habe um die Verdauung anzuregen. Ist das da auch so? Habe 50mg Tramadol-Ratiopharm. Eine kleine Toleranz ist vorhanden nachdem ich die letzten Tage Kratom konsumiert habe.

Edit: Kann Tramadol nasal konsumiert werden? Eigentlich ja nicht da es in der Leber zu odsmt metabolisiert wird, oder seh ich das falsch?

Hi guys, good morning from Mexico!

So, I have a very high tolerance where i take 1 gram of tramadol and barely does it. 300 MG would knock me out before but my tolerance grew by time. I know I need a break but how much should I stop? And will exercise and eating healthy lower my tolerance quicker?

Anyway, hoping for good answers, thanks amigos :)

But it wasn’t easy. I’ve been complaining about pain for the last three years because my Crohn’s disease has been debilitating and degenerative over years of inflammation which then can turn into scar tissue. I had to have a Hemicolectomy in which they removed my descending colon and reattached my small bowel to the rest of my large colon. So I’ve been in a fair amount of pain since then and after all these years of complaining all they ever recommended was biofeedback, acupressure, yoga, meditation and tylenol - you know the usual stupid stuff. And they even kept putting me in a pain program that does not prescribe opioids where they wish you “thoughts and prayers” along with the previous mentioned “methods” of controlling your pain. But when I finally mention that I am switching insurances from Kaiser to Blue Shield of California next month in a grievance form, all of a sudden they say, “oh we recognize your pain and here are 40 tablets of 50 mg Ultram and from now on we’ll be monitoring your pain much closer. Like what the heck - it takes me threatening to take my reliable medicare insurance away from them for them to give a crap. Sucks having to go through this. 😞

I just wanna know what your highest dose of tramadol was. Im currently on 400mg and don’t feel that much. I read that this should be a high dose already so I’m just curious if I should take even more?

Title says it all! Safe combo?

I love ket and always thought that's how euphoric opioids should be. I never tried opioids but got hands on 50mg tramal tablets.

How many should I drop? Does it combine with ket well? What kind of trip i will be getting and what's best activities? Should i add some weed to mix?

Which one is better?

Do you think that with a dose of 5000 mg taken at once (this is the first time I have taken tramadol), I would die.

I am considering taking it to die, hence my question.

So I used to be on oxys for a bunch of surgeries. My doc cut me off almost 2 years ago. Now I’m on tramadol for other reasons and I told him it’s not strong enough and I was worried about the withdrawals and seizures etc.

He said that’s not a thing with tramadol. It’s much safer than oxycodone. And he refuses to give it back to me. He switched me to 100mgs twice a day of tramadol from 50 mg. Even tho I’ve been taking 150-200 at a time

I just don’t get it. Everyone here says it’s way worse than oxy. Much more dangerous. I explained to him how easy it was to get off of the oxy and took like 5 days max. And how having the oxy help me on a daily basis is worth the little withdrawals I would get when cut off. He still didn’t agree.

Apparently docs don’t agree with tramadol having anything to do with antidepressants or SNRIs. They said it’s a mild opioid.

So what exactly is it? Does it say anywhere that it is an SNRI? Or this is just ppl saying this based on how they feel. Idk what to think anymore.

I tried getting off of this and he was about to tell me to put topical ointments on instead so I said nvm up my dose lol

Im on zoloft 100mg. Is it okay to take tramadol too?

I took 137 mg tramadol about 7 hours ago am I good to take another 100mgs? I use to eat them like candy when I was younger not knowing of the seizure risks& at the time I was taking around 5-8 50’s a day. Unlike most people Tramadol gets me pretty high and puts me in a great mood. Thanks for the responses!!

k so i just took a 100mg of tramadol cuz it apparently gets u high, i don’t feel anything yet.. what should i expect?

Little back round information my dad was in a extremely bad car accident and was prescribed Xanax tramadol and another bottle that I didn’t look at cause I was to amazed at the xans I just found.

So my drug seeking self was fiending for anything to get high on. I was big into cough medicine at this time taking countless triple cs in a night sneaking out with my friends running from cops you know the classic hooligan shit. Back to what I was saying so I was always going through the bathroom med cabinet looking for anything to abuse I go into my dads room and was looking in his room I open a cabinet by the sink move a couple candles and I see 3 prescription bottles. 1 was xanax the peaches another tramadol and the other I didn’t see cause I was way to excited. So I grab half the bottle of the xanax (was full). And took a handful not sure how many even snorted one thought I was being cool. Again with the tramadol handful down the gullet. This is where shit gets fuzzy. Not sure how it happened but my dad was screaming at me asking what I took fast toward sometime I’m outside attempting to play basketball to prove my sobriety as one does and it was a reck as you could imagine falling all over myself not even coming close to the rim. Fast forward again a little bit I’m back inside and my step mom is on the phone with my grandma I would stay there for a couple nights cause me and my dad were going to fight . This happens every time. At this point my brother was on the phone with me told him I love him and booked it out the door. I went into this abandoned place where me and my friend had some weed and money. So I went there after I picked it up my bartard brain didn’t think to wait until it was dark to get a lighter. So I start walking down the road and 2 cop cars pull up aside me I have weed and about 300 on me in cash. And not to mention he bong I’m holding. I throw the bong in the grass keep the bud in my pocket he tells me to get in the car that’s when I started getting a little itritated to say the least. After that I remember getting shoved into the car. For some reason without handcuffs so he is driving me back to my parents house. The weed I had wasn’t a lot was in a runtz type bag. When I get back they tell me they found the bong and they need to search me. I forgot to mention I put the bag in my ass and tried to shove it as far as possible but the corners of the bag are sharp asf. Managed to get through it without them finding the

I have 100mg tramadol pills and some 2mg alprazolam bars. Can i take 1 of each and still be safe. I know its dangerous mixing benzos and opiods, but is it safe in this dose? Thanks in advcance

A user has issued an alert about a batch of O-DSMT that they believe may have been mis-sold and contain a different compound instead.

Unfortunately neither they nor a friend have any test results so there is nothing to go on at this point apart from anxiety after consumption.

The takeaway from this is to Test. Your. Shit.

By testing your drugs you are helping yourself, you are helping the community and you are helping to prevent dishonset vendors from getting away with being dishonest.

Even a single reagent test is a billion times better than no reagent tests, and multipacks cost $30 and are legal. There's really no reason to abandon yourself and the community by not testing.

If the claims about this O-DSMT are true then a reagent test will detect this instantly, without question. If this information is forwarded then an alert with more detail will be issued.

Edit: Reagent Test Results:

> symbol indicates that the colour changes over the course of the test (1 minute)

You can see a list of vendors selling reagents in different countries here: https://www.reddit.com/r/ReagentTesting/wiki/test_kit_suppliers

How did it work for you? I had my surgery yesterday and they've given it to me twice. It seems to help but I've heard negative things about it and that's what they're prescribing me for home.

Ive been drinking daily for 2 months to the point I only live for that, every morning i throw up, ive been eating poorly but im sick of that..in the past ive had trouble with clonazepam, addiction. But everytime I use clonazepam I feel amazing, outgoing wanna do a lot of stuff, very social but I know thats another addiction. Could it be im depressed? I also took 1000 mg of tramadol to replace weed cause i cant get any at the moment. I dont want to use clonazepam daily but it helps a lot in tons of different situations. Like work, socially, with my family, I just feel better.

I want to get my life together, be happy like I used to be but i dont want to abuse clonazepam again. Ive been clean 3 weeks until today. I just want to know how you guys see my situation.

Thanks in advance, ill really appreciate any helpful comments!

Greetings my friends from Mexico :)

So i bought a bottle of trams at a mexican pharmacy. I experimented a couple times. The last time i took 400 mgs spread out over two hours or so cuz i heard it works better that way(on an empty stomach too). I felt something but not really an opiate feeling more of like the anticipation feeling of a comeup of some drug but that’s all i got.

i had a small opiate tolerance from taking kratom and tianeptine many days in a row before this.

so my question is can i get anything out of these? should i take a bigger dose and risk seizure(i’ve never had one in my life) or should i just take the L on these?

So I got my hands on 5 50mg tramadols, I have no opiate tolerance, I tend on smoking weed while/after taking them. But how many should I take and how should I take them?

So tramadol used to get me fucked up. Like really fucked up from just 200mg. Then recently i bought a box of 60 (legit pharma, came in packaging snd blister packets) and they worked for 2 days but not nearly as well to get me high. I took a high dosage on the 3rd day (300mg) and felt nothing. Did a higher dose the next and nothing. And again the next day. Presses aren't a thing here so it cant be that but I'm just so baffeled as to what happened. Any explainations? I should also mention i took a 2 or 3 week break before taking the next dose.

Edit: Would clonazepam, alprazolam or quetiapine affect potency?

So I’ve been taken tramadol (200 mg) everyday in 14 months, and I want to stop this habit before it get worse. But I feel like without tramadol I can’t feel happy again? Is it really possible to feel happy again without it, when I’ve already been addicted to it? I feel like it’s not possible, and I really want to know if it is possible. Cuz then I will fight this battle if it IS possible. If not, then I don’t see a reason of stopping.