Major Depressive Disorder Puns

This is my first time posting on reddit, please bear with me:

I work at a very popular flatpack furniture store, started in may 2021 after moving across the country. I have major depression due to being abused and neglected as a child, and my moving was so that i could access better healthcare with the state and start working to better it. Even being states away from my hometown, ive had to deal with an insane amount of fallout from my family (grandma passing, mom is insane, fighting over the will, etc), and have had to take alot of sick time to deal with it. Even with that,I try my damndest to put all my energy into my shifts, and every other manager in the store has praised my exceptional customer service skills. I have never once told any of my management about my depression because its something im trying to fix, not something im using as a crutch for excuses or benefits.

My direct team lead/manager is a boomer, and things started great but he would always comment on how tired i looked when i clocked in. He would ask how i was doing and i would usually reply with "Tired, but trying my best". After a point he pulled me aside for a talk, telling me about my absences. He then proceeds to tell me that im being a "downer" and if i keep it up, nobody will want to work with me. It seemed unreasonable, and i talked to my coworkers, who told me he was putting words int their mouth. We all joke about it and meme that we cant say anything sad or else we'll be "downers"

Jump to now, i had to use all of my sick time and PTO in 2021 thanks to family issues and 1 small effort to try and take a rest day between the chaos of my life, and my manger pulls me aside to berate me, saying that in all his 15 years of working there hes never seen anyone as bad as me, that i dont look like i want to be there, and that all my coworkers hate working with me because i put more work on them because of my absences. He threw my requested days off back in my face, saying he doesnt have to give me them (i requested wednesday and thursdays off) and proceeded to schedule me every thursday moving forward. He tells me that he hears everything and im not supposed to tell others the things he tells me....

im honestly so lost on how to handle this or if its worth going to hr? I assume i have no standing because of my absences but every single one was properly covered? I never told my manager the reason for my absences, and i shouldnt need to, but now i feel like i have to give this ma

Maybe we can benefit from each other. I know for a fact that older individuals can learn a lot from younger ones too.

I prefer using Facebook or Discord for communication, but reddit is fine too.

Its going to be my first time with psilocybin, i dont plan on taking any more than 1gram, maybe even less if i end up changing my mind, i plan on doing it tomorrow because i didnt sleep today and dont want to risk anything at all, what im particularly anxious or hesitant about is the risk of paranoia or HPPD or anything permanent

If I truly put in a lot of effort into helping myself, is it possible to treat my clinical depression without medication? I know it’s possible if it’s mild or moderate but I’m not so sure about the consensus on major depression. Thank you.

I was recently given a 70% rating for "major depressive disorder single episode severe and bruxism".

I cannot find anyone who can give me a definitive answer on whether this qualifies me for free dental through the VA, even the VA dental office.

I have been told that since the Bruxism is tied to a compensable rating that I qualify for free dental. I have also been told that Bruxism is not a rated as a stand alone disability under the VA Dental guidelines.

Is there anyone out there that has this type of title under their VA disabilities? Whether tied to depression or PTSD, and if so, do you get free dental treatment through the VA?

I have taken lexapro, prozac, Viibryd in the past. my MD wants to start cymbalta. my anxiety and depression has been so bad... can anyone share some positive experiences they've had with cymbalta?

I'm talking about both illnesses having independent causes from each other. Growing up I'd get unipolar hypomania. Now depression has come into the mix.

What makes me curious is that medication has almost eliminated my depression.

My theory is that the meds got rid of my MDD. My bipolar moods are back to what has been happening originally.

Hard to explain lol

https://jamanetwork.com/journals/jamapsychiatry/article-abstract/2772630

Just wanted to leave this here :) An accredited, peer-reviewed clinical trial with quantitative measures discussing the efficacy and positive effects of psilocybin for those who suffer from Treatment Resistant Depression, according to the DSM-5 criteria. Great trial, super informative, and clinically proven that yes, psilocybin consumption in a therapeutic setting is in-fact efficacious and helps people for weeks, if not moths, reduce symptoms of MDD

In a nutshell - I am 67 y male - never had a close friend in my life, suffered many break downs, three suicide attempts, in mental health hospitals three times, once for three months, while there I was threatened by drug addicts, had 12 x Electro Shock Treatments, the psychiatrists told me that I have PTSD and Asperger.

Now I am living the dream by myself, I found the answer to all my issues, when I was informed that there was absolutely nothing wrong with me, and that I am an INFJ, I began to find myself, I began to become happier with myself, I found that for me becoming a 24hour 7 day a week nudist helped my mental health tremendously and so I stay home for 3 weeks in a secluded spot on top of a mountain surrounded with all sorts of birds and Koalas etc, and I go to a nudist retreat for one week and meet other like minded people who I can talk to or ignore. I have found myself and am happy, even though I still have no one close that I cam talk to.

does anyone know the differences between persistent depressive disorder and major depressive disorder? google isn’t very helpful.

I am on Prozac, Wellbutrin, and Trazadone. I am wanting to start my LSD micro dose journey but haven’t seen much research on how this might effect me, if at all. Has anyone had a similar experience?

TORONTO--(BUSINESS WIRE)-- Cybin Inc. (NEO:CYBN) (NYSE American:CYBN) (“Cybin” or the “Company”), a biopharmaceutical company focused on progressing “Psychedelics to Therapeutics™” is pleased to announce that it has confirmed a scientific advice meeting with the UK Medical and Healthcare Products Regulatory Agency (“MHRA”) for the first quarter of calendar year 2022. This program milestone brings the Company closer toward advancing its lead investigational candidate CYB003 into clinical development for the treatment of major depressive disorder (“MDD”) and alcohol use disorder (“AUD”).

“Encouraged by positive preclinical findings that demonstrated the advantages of our novel deuterated psilocybin analog over oral psilocybin for the treatment of mental health, we are moving rapidly to progress CYB003 toward clinical development. We are looking forward to engaging with the MHRA to determine next steps for our clinical development path evaluating CYB003 for the treatment of MDD and AUD in the UK,” said Doug Drysdale, Chief Executive Officer of Cybin.

“CYB003 was designed to address the shortcomings of existing treatments, while retaining the therapeutic benefits of oral psilocybin. We believe that CYB003 has the potential to achieve better patient outcomes, including less variability, faster onset of action, shorter duration of effect, and improved brain penetration. As a society, we need to prioritize the treatment of mental health, and Cybin is committed to taking these next important steps toward progressing psychedelics to therapeutics,” concluded Drysdale.

On November 8, 2021, the Company reported preclinical data for CYB003 demonstrating:

• a 50% reduction in variability compared to oral psilocybin; indicates potential for more accurate dosing in patients with MDD and AUD;
• a 50% reduction in dose compared to oral psilocybin; indicates potential to maintain equivalent efficacy while reducing side effects, such as nausea, in patients wi

Hi everyone, I'm looking for some helpful books relating to major depressive disorder and s----de survival. Especially since this last year, my severe depression has really peaked. In 2021 I was hospitalized 3 different times for s----de ideation and could use a good book or workbook to help me think things through while I go through the rest of this journey with myself, loved ones, and therapy.

A lot of the books on depression that I've read don't really tackle topics of lifelong major depressive disorder and focus more on less complex depression. That can be really helpful in some ways, but I'm looking for something that hones in especially on MDD. Thank you all for your suggestions.

Note: respectful comments only please, I'm really hurting here and am not up for any hurtful responses.

Is there always a underlying traumatic incident behind MDD or is it the nature of the disease itself that makes it chronic in nature? Please help me understand this disease.

Like I said I have major depressive disorder and it’s pretty hard to function sometimes. When I get a job it does become a little bit easier but then I don’t get any raises and it becomes harder to go back once I feel unappreciated. I hate having to go to the same place constantly everyday, and I’m not a social person and people get offended when I don’t talk to them. I’m just not talkative. I keep to myself and this has been a problem with every single job I’ve had. Eventually I kinda just gave up. My parents are kicking me out soon and im only 19. So it’s kinda hard now. Idk just wanted to vent

I dont know where to get started. My brain is barely functional as is my body. I lay in a dark room every day under the covers on a laptop distracting time, living for others out of selflessness. Things have been getting incredibly bad recently. Again if I were to go write my history/upbringing it would be a novel. My father is a barbaric sadistic actual psychopath, met my mother (who is from the southern US, and happens to be bipolar and on the autism spectrum).... in Japan, because they were both there for their passion of shotokan Karate which they're both high ranked black belts in.

Like fuck I was born in the dirty south, uprooted first at like 5 yrs old to Jordan went to kindergarden there in the most ghetto place in Zarqa and of course was traumatizing and a huge culture shock. Like my mom who is/was a muslim convert at the time was very strict and got stricter and stricter with my upbringing, to a point of extremism and pushing beliefs on me that dont even fall in line with whatever her religion was. I luckily got to go to grade 1-4 grammar school in the US, but of course my bipolar autistic mother, who went on to have 8 kids, with a psychopath who married her for the green card, and she being of the catholic church and a virgin fell in 'love' with this abusive POS bastard, who from days within meeting her was smacking her around for looking at or talking to men or just doing anything he didnt approve of (oh and this man being a palestinian refugee who i guess grew up in a kuwait refugee camp, but was the fav./first son his father did everything for him (my grandparents were exiled in '48 bulldozed etc and spread to jordan and kuwait) he got some education in canada, and his poor illiterate father(rip) funded his lifestyle, and idk he chose to go to japan to pursue Karate and thats where they met.

He saw opportunity, and jumped on getting that green card. came here, opened a wholesale business, like 35 yrs ago, started small, eventually flourished, took advantage of hiring illegals for less than min wage and paying them under the table to do donkey slave labor in a sweat shop/warehouse/loading trucks. (And at 14 yrs old, because my mom was so strict in her islam and trying to keep me away from females basically/'mixed schools') i was always in and out of diff schools. homeschooled in some sketchy black womans apartment with like 8 other black students, this person was running a business out their home with no qualifications. it was awful and

I had my first therapy appointment today & although I am certainly depressed, I feel like my executive function is totally messed up. I tried to explain it to my therapist & he was really positive that I’m dealing mostly with major depression. I’m not sure whether I should be standing up for myself about the executive dysfunction or if I should believe the professional. How do I know?

Study: https://www.i-jmr.org/2022/1/e32234

There's a whole section on the gut microbiome and anxiety in the /r/HumanMicrobiome wiki.

Its going to be my first time with psilocybin, i dont plan on taking any more than 1gram, maybe even less if i end up changing my mind, i plan on doing it tomorrow because i didnt sleep today and dont want to risk anything at all, what im particularly anxious or hesitant about is the risk of paranoia or HPPD or anything permanent

Its going to be my first time with psilocybin, i dont plan on taking any more than 1gram, maybe even less if i end up changing my mind, i plan on doing it tomorrow because i didnt sleep today and dont want to risk anything at all, what im particularly anxious or hesitant about is the risk of paranoia or HPPD or anything permanent

does anyone know the differences between persistent depressive disorder and major depressive disorder? google isn’t very helpful.