Magnetoencephalography Puns

I’m supposed to have one soon, I have to go out of state for it. It’s not scheduled yet. But I have no idea how this thing works or what to expect or how long it will take or anything. Can anyone offer some insight?

PMID: 7640886

URL: https://europepmc.org/article/med/7640886
https://www.ncbi.nlm.nih.gov/pubmed/7640886

Thanks!

I was referred to a neurologist at a highly reputable large medical center in a very upper class neighborhood. Two weeks ago, I traveled half a day each way for the appointment.

I asked my new neurologist if he knew of a lab that offered a tau test. He answered no and that there are no blood tests for brain injury. There are blood test for brain injury. They are in the brain zapping: biomarkers wiki.

He ordered a MRI test. I told him I was concerned about the side effects of MRIs and that I would conduct research on tests. There are newer and more accurate neuroimaging tests. SPECT is more accurate and is not a new test. How come he did not order a more accurate test? I expected reputable medical centers to be up to date with new research and testing.

I will research side effects and select a neuroimaging test to ask for.

"Conventional neuroimaging methods, like CT and MRI, show advantages in detecting secondary injuries. However, newly developed structural and functional neuroimaging techniques such as diffusion-tensor-imaging, magnetoencephalography and single-photon-emission-computed-tomography improve accuracy and timeliness of diagnosis and prognosis in TBI."

"An important advantage of SWI is the detection of microbleeding, as it suggests the presence of diffuse axonal injury and is not seen on conventional MRI [65].......Wang Xuan and colleagues studied SWI combined with conventional MRI and CT images to prospectively analyze mild TBI patients 1 year post TBI. Their results showed SWI detected microbleeds that went undetected on conventional MRI and CT images."

(SWI is Susceptibility-Weighted Imaging.)

4.7. Magnetic Resonance Spectroscopy (MRS)

"Magnetic Resonance Spectroscopy (MRS), a molecular-based neuroimaging technique that reflects intracellular metabolic status as evidence of microscopic injury [137]. Common neuronal markers utilized during MRS include: N-acetylaspartate (NAA), a neuronal mitochondrial marker that decreases with neuronal loss or dysfunction; creatine (Cr), a marker for intact brain energy metabolism; and choline (Cho), a marker for membrane disruption, synthesis or repair. Increasing amounts of Cho detected in white matter is a breakdown product after myelin damage [138]."

"4.8. Single-Photon Emission Computed Tomography (SPECT)

"SPECT imaging was able to detect abnormalities in 66% of patients who had chronic symptoms following TBI, whereas MRI and CT did so in 45% and 34% of 29 patients, respectively [14

Link to Taylor & Francis site

Link to PubMed Citation

Citation: A magnetoencephalography investigation of neural correlates for social exclusion and self-control W. Keith Campbell, Elizabeth A. Krusemark, Kara A. Dyckman, Amy B. Brunell, Jennifer E. McDowell, Jean M. Twenge, Brett A. Clementz Social Neuroscience Vol. 1, Iss. 2, 2006

Thanks so much!

Being somewhat of cautious cynic when it comes to resting state connectivity studies, this paper has made me take a step back to re-evaluate them. Having a BOLD correlation at ~.1 - ~.01Hz is fine, but having that backed up by neural oscillations at the same frequency being generated in almost identical areas is damned fascinating!