Gemcitabine Puns

I had bep, ep, veip, radiation, surgery but cancer relapsed into liver anyway in multiple nodules largest being 5.5cm. Now i am receiving paclitaxel gemcitabine combo . Did anybody get this? I am starting to be sceptical that it will be cured at all and i might die from it.

I'm almost out of the endless testing phase and will be starting treatment next week. Just waiting on genetics confirmation, a final MRI, and for my Onc to confirm my PD-L1 status to determine if we'll be able to add immunotherapy. Contingent upon my PD-L1 status and genetics he is leaning towards:

Gemcitabine and carboplatin on days 1 and 8 every 21 days. So weekly for two weeks in a row and then one week off. If PD-L1 positive, we would add pembrolizumab on day 1 of each cycle.

I am familiar with carbo but not Gemcitabine. Wondering if anyone has been on that treatment and could maybe provide a little insight into their experiences with it and any possible side effects? Getting very anxious to start and so worried about being sick and side effects, which I think is just normal jitters.

It’s been a pretty good run for my dad lately. Nov 21 marked 1 year and last Wednesday his pet scan showed the tumor on the liver is gone, the pancreas tumor has shrunk, and best of all no current activity in the pancreas.

The oncologist increased the dose of Gemcitabine and Abraxane because his labs looked so good and there’s progress.

Today both his legs swelled up so bad he could barely walk. An ultrasound ruled out a blood clot and he’s on a steroid taper. This week he’s just getting Abraxane and no Gem. When the swelling is gone they’ll try the Gem again.

Has anyone had that reaction be a one time thing? Are there any things that help with swelling? We’re going to get some compression socks and see if that helps.

any thoughts on Gemcitabine + Abraxane ? My brother tried FOLFIRINOX but was too strong.

Sometime in the next couple weeks, I will probably be starting a course of four three week cycles of cisplatin + gemcitabine. If you've had this chemo I would deeply appreciate hearing about the effects it had on you and what helped you cope.

#1 Has anybody had success with Gemcitabine after trying folfirinox?

My brother, age 49 had only 1 treatment of folfirinox and it just beat him up too much. He just had J tube put in for nutrition / feeding and we hope he can try Gemcitabine in a few weeks.

#2 Anybody come off J tube / feeding tube after a few weeks or months ?

Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c00650

https://ift.tt/3ab7QPR

He literally got one infusion and then tanked with an infection, shortness of breath, fluid in his lungs, extreme weakness.

I think he’s pretty much been refused any more treatments as well. Apparently heart failure patients with left ventricular assist devices are very hard to manage with chemo. His pacemaker’s been going off like crazy as well.

They said his condition deteriorated so much so fast they want him to be in an assisted living facility. They want to shut his pacemaker off as well since being hospitalized isn’t every time he gets hit with a jolt it isn’t necessarily helping him. He’s trying physical therapy but not tolerating it well.

I was hopeful in the beginning where his tumor was stage one but now it looks kinda grim.

My mom died from this disease six months ago looks like he’s gonna following pretty soon.

Does anyone know which is better for metastatic cancer? My dad's Stage 4 has spread to the liver, they did the 5-fu (didnt work) now are trying the gemcitabine abraxane, but ive read that the Folfirinox is better- anyone have any insight/advice?

10.1200/JCO.2017.74.9564

http://ascopubs.org/doi/full/10.1200/JCO.2017.74.9564

https://www.ncbi.nlm.nih.gov/pubmed/29232172

SCI-hub doesn't work, so if u can have this article this could be awesome, thanks!

Hey all,

My mother (59, fit and athletic) has had a similar story to most that have been posted here. I'll post the timeline below, and leave my questions at the end for anyone who can speak to their experience or has medical knowledge that can be of help.

1. [Late November] Around last Thanksgiving, she was experiencing some abdominal pain and jaundice.

2. [Early December] We took her to the ER and had a gastroenterologist take a look. An ERCP was done, and we were told that there were no stones causing the blockage. A stent was placed in order to prevent future blockage, but we were still unsure of the cause at that time.

3. Her jaundice cleared up, and December passed seemingly healthily and uneventfully.

4. [Early January] Unfortunately, the jaundice came back around New Years. We were referred to another gastroenterologist at a different hospital. Another ERCP was done, and the existing stent was replaced with a larger stent. This time, the doctor informed us that there was a malignant mass found in her bile duct. We were told at this time that she had bile duct cancer. Of course, this came as a shock - we were devastated due to seeing her previous healthy self so recently and the lack of family history of cancer.

5. [Mid January] We immediately made an appoint with a surgeon to discuss a potential Whipple procedure. He was great - he answered all of our questions regarding the procedure, and he had performed over 30 of them in the past year. We knew we were in good hands. The procedure was scheduled for the end of the week.

6. She went in for a Whipple procedure to address the removal of her bile duct cancer. Unfortunately, this is when we found out the bad news - the previous scans had completely missed the mass on her pancreas, which was the cause of the bile duct constriction.

7. A 2cm mass was found at the head of her pancreas, which was successfully removed with clear margins during the Whipple procedure. The rest of her pancreas was clear - the majority of it (80%+) was left in tact. There were no signs of malignancy in the rest of her pancreas, bile duct, gallbladder, and liver. Unfortunately, a few (but not all) lymph nodes were positive for metastatic adenocarcinoma. She was given a diagnosis of Stage II-B PC.

8. [Late January] She spent the next two weeks recovering in the hospital and at home. Fortunately, there were no setbacks; everything seems to be healing correctly. She is now at home and recovering, albeit slowly. Her

What are the main differences between these drugs when prescribed individually (I’ve read paclitaxel is usually combined with gemcitabine) and in which situations would each be preferred?

Hi all recently I came across research from Colorado University on the effects of bitter melon juice on pancreatic cancer treatments that is showing promising results. My mother has pancreatic cancer and I have started giving her bitter melon juice daily. If you’re interested I have created a website compiling the research and am tracking my mother’s experience here:

Please replace "DOT" as "."

https://pancanfightersDOTwixsiteDOTcom/pancanfighters