I have an amazing doctor who specializes in women’s health and hormones and today she prescribed me Zyrtec for my PMDD, to be taken every day. She explained the relationship between PMDD and inflammation and it was really interesting. I’m excited to try it.
Has anyone else tried daily allergy pills/ antihistamines for your PMDD?
Edit: For those wondering, here's some of what I think I understand so far about the PMDD/inflammation relationship:
My doctor mentioned “mast cell activation syndrome” and said studies are starting to show it could be at the root of many disorders (or at least related), including PMDD. Mast cells are allergy cells and can get out of control in some people, causing systemic inflammation, chronic allergy symptoms, and possibly disorders like PMDD (there seems to be a strong link between inflammation and a TON of physical and mental health issues). So it sounds like taking certain histamine blockers counteracts some of that inflammation and can soothe a lot of those symptoms, at least for some people. Addressing inflammation in other ways (through diet, exercise, certain supplements, etc) seems to be super helpful for people's PMDD symptoms as well, so antihistamines might just be one more strategy for doing that that works well for some people.
Hayfever has been brutal for me this summer, and the pills I've been taking (histaclear) have done jack shit. Any suggestions?
We all know about the infamous finding that 1st generation antihistamines, such as Benadryl (diphenhydramine) have been shown to cause dementia in long term use.
My question is, do 2nd gen antihistamines carry the same risk? They don't have the same anticholinergic properties, but maybe I'm missing something, because Cetirizine works great as a sleep aid for me currently. Yet I can't shake the feeling that the diphenhydramine study has left me with.
I’m at the point where I’m miserable & have to do it. I just need to mentally prepare
1st Gen antihistamines are said to be linked to dementia; Are there any second gen substances that will give similar effects as Benadryl, minus the risk of dementia? I’m aware that it will most likely need to pass the blood brain barrier so I’m open to using a secondary substance to potentate it, if that needs to be done depending on the recommendation.
Edit: for recreation/delirium
29M, relatively healthy non-obese and about a month after COVID I developed chest/cardiac related issues, chest pain/discomfort, palpitations, chest tightness, burning/tingling sensation all over chest, costal joints enflamed, shortness of breath.
They peaked around month 3, where I had unbearable chest tightness, squeezing and shortness of breath (couldn't get that last 20% of breath in). and yes I've had the full cardiac workup (echo, tons of ekgs, chest CT W/Contrast, cardiac stress test etc...) all coming back normal.
Anyways, am starting month 5 now of LHC and my symptoms are quite a bit better, so much so that I've tried coming off of daily supplements and I noticed my chest pain started to really flare up again.
I noticed that I get this intense chest inflammation/burning/tingling, that 90% goes AWAY within two hours of taking an antihistamine. I typically take 2x Zyrtec a day (AM/PM). I think that the Backpod has helped a lot too, for Costo-related pain.
I am thinking I might actually have some form of Mast Cell Activation though? Has anyone else experienced cardiac symptoms that have been reasonably relieved with an antihistamine?
I also have relatively new GI Issues that have been very problematic for the last 2 months despite an exceptionally clean diet.
Looking for anyone with similar circumstances?
Hello,
I'm suffering from pois for about 4 years, I have seen a lot of doctors, tried a lot of stuff but nothing ever improved my condition even slightly.
I started to take Zyrtec (an antihistamine drug),eat antihistamine food and avoid high histamine food.
Also started to drink 2 matcha tea everyday (I'm not sure it's related but I really think it's making me feel better) and miracle after few days for the first time my symptoms was less strong and last way less long!
Before taking Zyrtec and eating antihistamine foods, my pois was lasting at least 4 days, sometime more, now about 2 weeks after taking Zyrtec daily, I only feel bad the evening after I ejaculate and the day after I feel not 100% good but I only feel the symptoms of pois very little, I'll say I feel 80% less symptoms that I would have before Zyrtec. 1 day slightly seek compare to 4 days very sick it's such an improvement and even if it's not perfect yet, it's making my life so much better.
The question that I would like to ask, if by any chance, others people was feeling better or totaly cured with Zyrtec or antihistamine drug? If yes can you say how long does it take you to feel beter? What antihistamine are you using, the amount and how often? I really think that antihistamine can help some peoples and so if you can share some experience about it, it will be helpfull!
I also hope that it can help some people who never tried antihistamine, if you want to try, I take 10 mg of zyrtec around 8 pm (but I don't know if when you take make a difference), the day that I have an orgasm, I take 5 more mg of Zyrtec right after and eat some chocolate( I can be 100% sure but I really feel that eating some chocolate right after make me feel better, it's a good antihistamine food after all). I also recommand matcha tea, again I'm not sure that it's really helping or not but I think it's worth trying.
Also if it can help, I will tell you more detail about my pois, it's usualy last 4 days but I had some period when it can last more than a week almost 10 days.
Taking shower (hot or cold) is triggering my pois, when it's happened I'm not as sick as I do after orgasm but still not feeling good (symptom very similar as pois) and last 1 or 2 days. I have to add that at the beggining of my pois, taking shower wasn't making me sick, it's just happened to me 1 year ago.
Eating some kind of food like brocoli will also every time trigger my pois and then I will feel sick same t
... keep reading on reddit ➡https://m.ufhealth.org/news/2021/two-common-compounds-show-effectiveness-against-covid-19-virus-early-testing
Viral persistence was (and still is) among the hypothesis to long covid. I stumbled upon the above article from University of Florida on two OTC compounds showing potential effectiveness against COVID-19 virus. The two compounds are antihistamine such as diphenhydramine and lactoferrin (protein found in milk).
"In lab tests on human and monkey cells, the combination was particularly potent: Individually, the two compounds each inhibited SARS-CoV-2 virus replication by about 30%. Together, they reduced virus replication by 99%."
Being active on sub for well over 6 months now, I have seen many posts on benefits seen with antihistamines and I wonder if these benefits were from simply blocking histamine or possibly via eradicating viral persistence?
There's another article on antihistamines being useful for long covid through a different mechanism that involves T-Cells.
https://www.news-medical.net/amp/news/20210608/Antihistamines-might-be-effective-in-long-COVID.aspx
It would be helpful to all of us if we could share feedback on beneficial effects observed with antihistamines. I'm willing to put this theory to the test and report back.
Which do you take? I’m concerned about side effects. I still have to work and can’t be benedryl’d out all day for example.
I like doing drugs but I need antihistamines, so I was wondering if it was safe to take both together thanks if u respond :)
You know since we agree that dph is the devil and may or may not cause an increased risk of dementia. Is there a reason to not say pop an allegra to deal with the nausea/itch people experience on a dxm come up?
My allergist suggested taking 10mg zyrtec in the morning with 20mg pepcid ac and another 10mg zyrtec at bedtime. It's not helping. Is there a better antihistamine that you've found that works better? (Benadryl does nothing ☹). Thank you!
I'm a new allergy sufferer, getting wrecked by Central Texas cedar fever. So far I've tried Allegra and Xyrtec, and both have made me extremely drowsy, to the point where it's worse than the allergies themselves...
Should I give the other non-drowsy antihistamines a shot? Or is it a sign they're not going to work for me?
Hi guys. I have some allergies for sure. Some seem to be airborne, skin touching, or "hidden", "invisible" allergies.
Such as, grass pollen/hay fever
Such as, house dust
Such as, dog dander
Such as, latex, which can even be airborne, or released into the air, when running a hot bath, and there is a latex bath mat
One solution is to wear a proper hardcore GVS P3 mask, which filters all tiny particles. But, I look ridiculous, when wearing that, like, some kind of scuba diver
Another solution, is to open the window. This at least lets some of the stuff out of the room.
Another solution, is to regularly clean surfaces in the house, especially bed sheets, pillows, because you can spread the allergies, from your clothes, to your pillow, and it enters, through the eyes, etc
Another solution, is to have showers, when you come home
Another solution, is to wear shoes around the house. This stops you touching the carpets, which these types of allergies, often get stuck in
But, a huge solution, and that is antihistamines
I am scared of antihistamines, because I have read, that they can make you sleepy.
I currently take a powerful ADHD stimulant medication. And you should NEVER mix sleepy type drugs with stimulants. I learned that the hard way, with sleeping pills, and also, with Sertraline
Do any of you take antihistamines?
Are these sleepy drugs?
Do they send you to sleep?
Are they comparable to sleeping pills or SSRIs, in how powerful, their sleepy effects are?
Bonus question. Do any of you, take antihistamines, alongside stimulants, Vyvanse/Elvanse specifically, or others, such as Ritalin etc?
I am basically scared to take any drug, that might be sleepy, alongside a stimulant
My ADHD is more important, than my allergies. I don't really get, rash, anaphylaxis type symptoms. Not unless I scrunch up big balls of sellotape or latex gloves or plasticy type stuff
I am just very curious about the side effects of antihistamines, especially if you have, ADHD, autism etc?
I’m pretty new to this, so I’m just wondering what I can expect in terms of management, I guess? My doctor put me on 10mg of Claritin twice a day, and while that hugely cuts down on the welts and the itching, I still find that I’m blotchy as fuck pretty constantly. I brushed my sleeve against my forehead yesterday and it looked like somebody had clawed my face. I wasn’t careful enough putting some sunscreen on my shoulder and was bright red and mildly inflamed for half an hour. I get vivid red marks from like...the seams of my clothes. Is this pretty standard, or should I be looking into a different medication? It’s not debilitating or anything, but I guess I’d like to be able to scratch my nose without looking like I got in a cat fight.
I've had some symptoms of histamine related issues for the past few years, including brain fog, bloated skin, stomach aches and scalp itch, but the worst is a progressive thinning of my hair. I've recently tried using a few anti histamines and they work, all of these issues go away with a single dose but I get side effects with the ones I've tried.
Cetirizine completey sedates me. I imagine it would be hard to function if I was on it all the time.
Loratadine and Fexofenadine work as well, but I get chest pain and tightness whenever I use them.
I might try some other AHs and some natural remedies as well, but does anyone know of any other potential solutions? Is there a topical AH that I could use which maybe doesn't go systemic so there's less side effects? Cetirizine mixed into shampoo? I tried a topical solution of cetirizine but it was even more sedating than the oral version.
I am prone to flushing, although it is very random at times. Sometimes with food, other time a couple hours later.
I’m very sensitive to hot rooms, especially going cold to hot. Sometimes I have an evening flush that seems to be appear for no reason at all. I would say the majority of my flushing is towards the end of the day.
I believe I have some combination of rosacea/MCAs/histamine intolerance.
I have started a low histamine diet, quercetin, DAO Histamine Block for high histamine meals (going out to eat), and am also trying l-theanine and ashwagandha.
Further, I’ve read some of you have had success with H1/H2 antihistamines. I have taken Claritin and Pepcid the last few days, once when waking up, and once at night. My flushing has not happened for the most part, but this could also be because of my dietary changes.
I’m wondering if anyone else has had success with antihistamines, and what you are currently taking, along with any recommendations.
😊
https://clinicaltrials.gov/ct2/show/NCT02521311
from what i could gather this clinical trial is focused on people with optic nerve demyelination but celastine funerate has also been studied a little bit in the past in MS patients.
i’m currently on dimethyl fumarate as my DMT and i found it peculiar this antihistamine, clemastine fumarate commonly used for allergies has potential to stimulate growth of the myelin sheath. idk they both have funarate in the name! haha
i’m sure someone has posted about this here before i can’t read every post but what do you guys think? heard about this before? gives me a bit of hope.
anyways i hope everyone is having a good week and staying strong. big love
I’ve found that the last two months that I’ve been on antihistamines, my period cramping has been significantly less. Wondering if there’s a correlation or not!
title. basically i’m covered in hives and don’t really have access to benadryl for a reasonable price (50 miles from a pharmacy) i do however have plenty of datura ointment which i use for sleep and muscle pains. i know dph and daturas alkaloids are similar in how they react in our bodies but not the same so this is just a shot in the dark but ya i really need some medicine rn lol
Hello, I am recovering from the virus and have been having issues with mucus/phlegm. ive taken generic mucinex and other expectorants but yesterday I made the mistake and took a antihistamine and now everything is dry and thicker. Any ideas on how to loosen this?? I’ve done tea, face steam, drinking water but this stuff is not budging at all. Should I try another mucinex at this point or will that worse?
Hi, Im currently dealing with some autoimmune issues and am looking to do a keto based diet with foods low in histamine. Im eating mostly chicken and turkey, which have little to know fats in them. I also est red meats from time to time since its much more rich in fats. I know keto/antihistamine diets are extremely limiting (especially together), but if there are any antihistamine foods/oils that are high in fats that you can recommend it would be much appreciated!
Hello all,
I have been able to significantly improve my symptoms over the last few months/years. Partly through the treatment of my specialist, but also through self-experimentation. I have found that in my case an additional intake of antihistamines (desloratadine) has a clear positive effect. I would like to share this experience with you - maybe it will help one or the other.
Since I am going to elaborate a little, I'll try to structure the post so that you can skip parts if necessary.
From the first symptoms to the diagnosis:
I think it all started at the age of about 15. At that time the symptoms were still very weak and I didn't take them seriously. Over the years, they very slowly became stronger and stronger and I spent a lot of time trying to exclude different foods or try other things like intestinal cleansing, healing clay or probiotics (unsuccessfully). In the summer of 2018, at the age of 23, I finally decided to go to a specialist (yes this could have been done earlier), who then gave me the diagnosis of Ulcerative Colitis after various tests and a colonoscopy. -- Which, by the way, I was actually happy about at that time because I finally knew what was wrong with my digestion.
The specialist's treatment:
When it came to treatment, I probably followed a fairly typical path. It took a while to find a suitable treatment. The main trials/medications were, in chronological order:
- Claversal - still taking to this day, little effect, no side effect.
- Cortiment - taken a few weeks, hardly any effect, got pneumonia at the same time
- Prednisolone - taken 2 times in spurts, good effect - but only at high dose (must not be taken permanently at high dose because of strong side effects)
- Azathioprine - taken for 4.5 months, medium effect, unpleasant side effects (e.g. permanent nausea)
- Vedolizumab - infusion every 8 weeks since Nov. 2019, relatively good effect - no more inflammation levels in blood and stool samples, no side effects
So with Vedolizumab we have now found a suitable treatment that has led to a measurable success. And I was able to increase my weight from 65 kg (at 195 cm height) to 85 kg over time, despite regular sports activities. Although from the doctor's point of view everything was actually fine, I myself was still not really satisfied with my symptoms.
My self-experiments with histamine:
Since I was still not completely satisfied with my symptomatology despite good medical t
... keep reading on reddit ➡hey there! i recently had an issue with benadryl & stopped taking it for an allergic reaction i was having. i’m taking zyrtec now, but i feel like it has been messing with me too. i’m about a month into my anticonvulsant dosage increase & in past experiences, i tend to have more smaller/focal spells/episodes/seizures when the medication levels out in my system, & then the issues taper off. (they don’t disappear entirely.) however, i feel bogged down & spacey since taking zyrtec. when i’m extra fatigued i kinda assume that i’ve been having episodes/seizures in my sleep. my neuro said it was no problem, but they seemed surprised about benadryl being an issue. had anyone had a similar, funky experience?
I take a pharmacy brand antihistamine daily to treat the brain/head fog I normally get from my seasonal allergies (which seem to just bother me all year) is this safe for the long term?
Or would it be better to try separately? I have to suggest it to my doctor, that’s why I’m asking. I don’t know how can I help myself anymore haha. More about me: 21F, ME triggered by covid and mono, also diagnosed with hEDS and CCI lately. Neck collar helps me with ME and POTS symptoms but I don’t wear it all the time. Anyway, happy new year 🥳
Which type/brand of antihistamines worked best for you?
Im currently having a flare up of the chest pains and Ive not tried antihistamines yet so any advice is welcomed.
I am in the uk if that helps
I have the foods that cause me problems pretty well figured out and avoiding them works great for me. The list of foods is long, but I’m lucky to know them. I have considered taking Benadryl and having a giant meal of my favorite banned foods. Anybody done this?
It’s hell week and I woke up this morning pissed at my partner for an irrational reason. Also did not have a shred of an appetite this morning. Took some edibles that have both THC and CBD and an antihistamine and now I’m absolutely chillin on my back porch, basking in the sun, and appreciating the beauty of the forest. Eatin a healthy smoothie and some avocado toast. My anger has been dissolved. Crisis averted.
Thank you!
Willing to try anything at this point. Currently trying Claratin, Zyrtec, and Pepcid to see if it works. Is 2 weeks enough to see if it’s effective?
Ultimately trying to find something that helps with heat related flushing. Going to try clonidine after this experiment, which I suspect will work best. Beta blockers have been effective for anxiety flushing, but not heat
As a firm supporter of the scientific and medical revolution and appreciator of all that which our great doctors have created, I am very considered about the anti-antihistamine rhetoric circulating throughout this fine subreddit.
Though they might be synthesized (by trained scientists), such compounds bring one far closer to the natural world than any amount of sobriety or devil's lettuce could hope to. Only through the pink lens of DPH have I been able to bear witness to such wonderful creatures as the flying spiders or laughing flowers. I daresay the compound has opened my eyes to the glory of God's creations which would otherwise be forever hidden to me under the veil of sobriety. Only through massive doses of allergy medication does He truly reveal Himself.
Hi, I’m a 22 yo woman and I’ve tried Zyrtec, Claritin, FloNase, Allegra, and Xyzal.
Zyrtec and Claritin took away most of the feeling in my legs and the general lower half of my body every time I took them. I tried for weeks and it never went away.
Allegra gave me headaches and leg pain and I just generally felt bad while on it.
FloNase and Xyzal didn’t help much.
Is there another anti allergen I can try, or some reason/something to counteract the side effects, especially the loss of feeling in legs?
I have read some people take antihistamine during IVF. Why is it used ?
