G Protein Coupled Receptor Puns

I said I only know the first couple of digits, but I'd be willing to fake it if that's what's going to moisten the clam.

You give her a couple test tickles.

Protein

A couple are arguing about whether they should cancel the picnic they had planned.

It's kind of cloudy, but the wife still wants to go because the forecast looks ok.

The husband, however, heard from their cranky old Russian neighbor Rudy that his joints were achy, and that he was certain it was going rain that day.

The couple argues for a while. The wife insists they should listen to the weather man over some crotchety old neighbor. The husband is equally insistent that the neighbor is right about this. After some back and forth, he finally turns to his wife, exasperated, and says:

Rudolph the red knows rain, dear.

Lookout for a couple of hardened criminals.

Over the past couple days my dad and i have taken turns coming up with santa based dad jokes, today is my turn but im completely blank. Anyone got any good ones?

Over the last year whenever I order something online from a small business I make sure to write "write a dad joke on the invoice" in the memo section at checkout.

I've gotten some lame ones like what did the ghost say to the bees? Boo-bees

I've gotten some good ones, even had a gun store give me the shatner panties joke

But today's just hit peak dad joke status....

They included my invoice sheet and a separate sheet of printer paper with nothing on it but the words "a dad joke" in like 200 size font.

It's short, sweet, super corny and makes you facepalm, but still had me laughing out loud for about five minutes.

Bravo good sir, you definitely have a couple of kids at home that get lots of practice rolling their eyes

The speaker mentioned that 85% of couples are so disconnected the husband doesn't even know his wife's favorite flower. I leaned over toy wife and said

"It's self-raising, isn't it?"

Worse than the costume idea was the frequent wardrobe malfunctions that came about throughout the evening. Luckily for everyone the couple would manage to get a hold of the situation before things slipped down too far. Though unluckily for everyone, the guy would always end this awkward real-life recurring slapstick segment with the even more awkward dad joke: "what a releaf".

I was browsing when I saw a couple of loves fused together looking quite fallic. I asked the Baker which one that was. It was the Dill dough

The guy was tired after biking over 300 miles in Arizona. He decided he would hitch a ride. He started thumbing and this dude pulls up in white sports car.

The driver of the white are is like "I can give you a ride but the bike won't fit..." Well they get to talking and decide that they would tie a rope around the frame of the bike and the driver would tow him along slowly. The driver told the bicyclist to just use his bike horn if he went too fast.

At first, our cyclist was not sure but after a couple of miles....it was nice. Going along at a nice pace without needing to keep pedaling.

Well, after about 40 miles they get into town and get uip to a stoplight. Well, this red sports car comes up and the two drivers start eyeballing each other. The engines start to roar.

The light turns green....and they are off.

The two cars race past a billboard where a police car has set up a speed trap. The older cop, Dan, says to the younger cop, Jim... "It is definitely time to retire."

The younger officer, who just looked up from his phone and asks "Why Dan?"

Dan's reply? "I just saw two cars drag racing with some idiot on a bike honking to pass"

I said seefood.

He replied by saying "Very good. Seafood is a good diet to follow. It's rich in protein which you need"

I said, "No doc, not sea food, See-Food whatever food I see, I eat."

He paused before saying "No wonder you have to visit me".

An older American couple visits Russia for the first time. They are a little concerned about the language barrier as neither speak Russian. Luckily they find a very friendly cab driver named Rudolph at the airport who speaks fluent English. He gives them his mobile number and says he'll be happy to drive them anywhere they need to go during their stay.

The next morning the wife calls Rudolph and asks if he can take them around to several of the sites. He agrees and warns her to bring an umbrella as it's going to rain today.

She tells her husband who promptly looks out the window and sees clear blue skies. He says the cab driver is just pulling her leg and refuses to bring an umbrella.

The cab picks them up in front of the hotel and they have a very nice morning seeing the sites. Just after lunch the sky starts to fill with dark clouds. The cabbie reminds them to take there umbrellas at the next stop as rain storms in Russia can be severe.

The wife turns to her husband and says .....

See, I told you! Rudolph the red knows rain dear.

... I'll see myself out now ...

They notice a sign for the watchtower challenge. They ask the tour guide what it’s about and he says “if you can drop your watch from the top of the old watchtower and catch it before it hits the ground, you win a million in gold to take home.” The Englishman goes first, drops his watch and runs down the steps, but he’s got no chance and his watch is completely broken. Then the Scotsman tries: he throws his watch up as high as he can to get more time, but his watch also smashes on the ground. But then the Irishman goes. He drops his watch and casually strolls down the watchtower steps. He goes straight over the road for a couple of drinks at the pub, and plays a game of pool. He then walks back over the road, waits a few minutes and catches his watch. The tour guide asks, “how did you manage that?” and the Irishman says “it was easy… my watch is an hour slow.”

A power couple

On Christmas in the Soviet Union, it was a very misty day. Sometimes the mist would be so thick that it was almost like rain. In the town square a couple were having an argument on if this weather would be considered rain or not. To settle the dispute the husband said they should ask the Town Guard, Rudolf. His wife, not thinking Rudolf would be much help asks "Why him? What does he know about rain?"

To which the husband replies "Rudolf the Red knows rain, dear"

The first one turns to the other and says, “you know I beat Bobby Fisher a couple of times and even taught him a thing or two.”

The other one replies, “that’s nothing I took Kasparov, and Botvinnik down on a regular basis.”

The two continue conversing and becoming more animated in the stories of their Chess matches and conquests.

Finally a manager approaches and clears his throat. “Excuse me gentlemen. We’ve gotten a couple of inquiries about your discussion and unfortunately I have to ask you to continue this in your rooms or at the bar. We simply cannot have chess nuts boasting in an open foyer.”

A couple angry beasts seeking revenge.

The other day, we took our kids (2 and 5) on a hay ride at a seasonal event hosted by a local farm.

When the hayride ended and we were getting off, the couple in front of us pointed out that a nearby goat was eating grass with it's head poked though a small hole in the fence. To my comment "See, the grass really is greener on the other side".

I turned and there was no reaction by my family, or the couple, but I was overjoyed at my joke. Looks like I'll have to get used to this reaction.

She asks a women's forum about tips and any possible side effects, being quite worried as this is her first child, she's very late into being pregnant and etc. A couple of hours later she receives a reply, and, with shaking hands, starts to read it: "I had a friend who was in the exact same position as you, and she decided to get her tooth removed. All should have been fine, but, there was a side effect: when the baby was born, it had no teeth."

I said that's really nice of you your honor. Maybe I can kick in a couple of bucks myself.

A European couple went missing while hiking in the Alps. One was Polish, one was Czech. A little while after they go missing, some park rangers find a couple of dead bears, one male, one female, just off the trail, their bellies distended. They cut open the female and find the Pole.

"You know what that means." Says one ranger to the other.

"What?"

"The Czech's in the male."

It was a rough couple of years but he turned himself around.

My wife and I were out walking the other day and we were trying to get home pretty quickly to beat the rain.

We were passing through the park and passed a man walking 2 dogs when I said the rain is getting close. My wife then said "yeah I've been seeing a couple of spits" to which I replied:

"Uhh, I think they were a different breed, but I could be wrong"

I heard the most disappointed groan from her, which is music to my ears!

At least a couple grahams

She excitedly says yes, and the boy spends the entirety of the next day preparing for the big day.

The first thing he does to make it extra fancy is to rent a limousine for a day (yes, he is rich), but when he arrives at the rental center, he notices that many other people had the same idea. There was an enormous line that stretched out the building. Nevertheless, this boy was determined to make this night a special night, and waited for hours. Luckily, he succeeded in the end, and rented a shiny black limo. He was starting to get really excited.

After that, he goes to the tailor to pick up a brand new suit and tie to look as sharp as possible. But once again, the line for that wrapped around the block and forced the boy to wait another long hour. He sighed, but still waited in line, as he was quite persistent and knew it would be well worth it in the end. In the end, though, he got a perfect suit that fit him well. No wrinkles, no nothing; it was just pure handsomeness.

Then, the moment came. In his limousine, he once again drove up to his crush's house, well-dressed in the brand new suit he just bought. She came out looking stunning as well in an aqua dress that sparkled in the evening sunlight. Excited as ever, she leaped into the fancy limo and rode to prom with him, ready for the big night.

When they arrived, however, there was yet another long line into the ballroom, as many people needed to be accepted. It was quite a busy night. After half an hour of waiting, the couple finally made it through and began dancing. It was all going really well, and everyone was having quite a grand time.

A few hours later, they became thirsty and went to get a drink. Both him and his girlfriend were in the mood for fruit punch, but nobody else seemed to want it. When they entered the snack bar, they noticed more long lines of people wanting to get other snacks and drinks, but surprisingly... there was no punchline.

So, we're going to a Fulham football match, my Dad is meeting me outside the ground but he's running late. I spoke to my Mum asking where he is and she says he's not far away but in a bad mood because he's got a cold, he left later than intended and the traffic was awful!

He arrives and we walk in about 10 mins late and as we walk through the turnstiles, Fulham score and we hear a massive cheer from the stands, we're below the stands at this moment and can't see.

We take our seats and a couple of minutes later I look over at my Dad's phone. My Mum has texted my Dad asking if he's arrived at the ground ok and his text that he'd written out was "Yes, everyone cheered when we walked in!".

Bloody love that man.

...since he is a megastar with lots of clout, Buckingham Palace agrees and a few days later he gets his meeting with her.

"Your Majesty, a couple of months ago you ennobled an eye scientist for his contributions to ophthalmology," said Cristiano. "I saw it on TV and was touched by his story, how he grew up in poverty but eventually became this great and learned man. He reminds me of myself a bit, how I grew up poor but managed to become a great footballer."

"So," says Cristiano, "I decided to write a play about him, all about the study of eyes and how they work as well as the scientist's life story. I have brought the manuscript to you, so that you can deliver it to him in person."

Cristiano hands the Queen the manuscript that he is carrying. The Queen squints at his handwriting on the front page of the manuscript..."I'm going a little blind," she says, "please could you tell me what it says here?"

Cristiano replies, "Eye Play for Man You Knighted."

"Yes I know that, you idiot," replies the Queen.

Because they only ever eat protein Sheiks!

The Protein Shake

And a couple of other Japanese words too!

To find themselves a couple of ghoul friends!

There were a couple of uncomfortable silences…

A man was recruited for a space colony

He had been posted to a planet 14 light-years from Sol. As his ship landed on the planet's glowing surface, he saw a car waiting for him.

"Welcome to Anti-Earth," The driver said, "don't worry we are going to change the name soon. I am here to take you to your quarters and show you the colony on the way."

They had been driving for a couple of minutes when the recruit saw glowing buildings far away.

"Why are the buildings shining like that?", he asked.

"Didn't they brief you about the colony?", the driver asked "We don't call it Anti-Earth for no reason, it's literally the opposite of Earth. Any element rare on Earth is as common as carbon (C) here, and interestingly carbon (C) doesn't occur naturally here. So we had to make good of what we had, the buildings are made of rare metals like radium (Ra) which glow in the dark."

After half an hour they arrived at what seemed the main highway, the road had a faint bluish glow and the sides were lined with metallic posts shining faintly in the double moonlight. They stopped near a small dilapidated shack with the words "COMMUNICATION OFFICE" crudely etched on the walls.

"This is your office. You are supposed to handle communications for the colony," the driver said. "We can't use any wireless communication as the high amount of radioactive gases in the atmosphere interferes with the signal, so we have to use a type of telegraph instead. Come on, I'll show you our most important resource."

They walked a bit till they reached a plantation full of bizarre trees. Some were made of precious metals, some of common earth metals and some of them were glowing radioactively.

"This is the plantation for building the posts. We brought these seeds from Earth and planted them, apparently as they couldn't get the conventional elements they just used what the soil contained. We just sell the gold (Au), silver (Ag) and platinum (Pt) trees to Earth, the iron (Fe) and aluminium (Al) are used for constructing equipment and there are some pretty rare elements like uranium (U) and astatine (At) (which is the rarest element on Earth) which are used for scientific research. However, these aren't what we are here for."

The driver motioned him to follow him towards a small area of trees with a silvery sheen to them.

"These are made of rhenium (Re) one of the densest elements with one of the highest melting and boiling points. It is strong enough to withstand the toxic atmosphere and radioa

He taught me a thing or two in Spanish, and he's leaving in a couple months to go back to Mexico to his wife and two kids. What a nice fellow.

It was for a protein shake

I said, “No, only for the next couple of hours.”

So, she walks over and takes a seat next to him on the bench, turns to him and says, "Sorry to bother you. I know this may be a little forward but I would love to grab coffee with you some time."

Flattered, the man responds, "Sure... but what makes you so certain you and I would get along so well?"

"Well..." the woman says. "A couple things, actually. I noticed you were wearing an Iron Maiden t-shirt. Iron Maiden are my favorite band of all time. When they went on their reunion tour in 1999, my parents took me to see them in Cleveland. I was 12 years old and it was the first concert I ever went to. I absolutely love Iron Maiden."

The man can't believe it.

"I saw them play Cleveland in '99! First concert I ever went to on my own. My best friend Jimmy Spitz and I told our parents we were sleeping at each others' houses, snuck out, took a bus into the city and saw them play at the Plain Dealer Pavillion!"

Naturally, they're both shocked.

"If that isn't weird enough..." says the woman. "I noticed you're reading Mark Twain. I was a communications major in university and I actually wrote my thesis on Mark Twain and how he used satire as a lens to comment on current events of the time, comparing him to satirical news sources of today. He's my favorite author."

Now the man is really taken aback, "Get out of here! I was an English major in university! I specialized in 19th century American literature and this is like my fourth or fifth time reading Tom Sawyer, I absolutely love Mark Twain."

They both can't believe it...this has got to be a match made in heaven.

"Ok..." the woman says. "Well, buckle up because here's the icing on the cake. I noticed you're eating a prune. Prunes are my absolute favorite fruit. When I was a kid, my grandfather lived on a farm. He had an orchard that mainly grew apples and some lemons, but he knew how much my sister and I loved prunes so he kept a couple of plum trees. Every year at the end of the summer, we'd go up and harvest the plums with him. He'd dry them and by the time we'd go back to his place for Thanksgiving he'd always have those prunes saved just for us. They're my favorite fruit! I love prunes, you're eating a prune, this has got to be fate. What do you say?"

The man puts down his fruit and responds,

"It's a date!"

The owner of the place launched a daring proposal; -Whoever dares to jump, swim to shore and survive, I will give 1 million dollars.

Nobody dared to move, suddenly a man jumped into the water and desperately swam towards the shore while he was chased by all the crocodiles.

With great luck he arrived, taking the admiration of everyone in the place, then the owner announced; -We have a brave winner.

After collecting their reward, the couple returned to the hotel, upon arrival, the manager told him; he was very brave to jump, then the man said; -I didn't jump, someone pushed me!

His wife smiled ...

Moral: "Behind every successful man, there is a woman who pushes him."

A bloke starts his new job at the zoo and is given three tasks.

The first is to clear the exotic fish pool of weeds. He starts on this when suddenly a huge fish leaps out and bites him. He is not going to let a fish have a go so he beats the offending fish to death with a spade.

Realising that his boss is not going to be best pleased, he tries to find a way to hide the dead fish. He hits on the brilliant idea of giving the fish to the lions as lions will eat anything. So he throws the fish into the lion's cage.

He then moves on to his second job, which is to clear out the monkey house. He goes in and a couple of chimps starts throwing coconuts at him. Not amused he swipes at the chimps with his spade, killing them instantly. He's really worried now, so what does he do? He feeds the chimps to the lions, because lions eat anything. He hurls them into the lion's cage.

Anyway, he moves on to his last job, which is to collect honey from South American bees. He starts on this and quickly gets attacked by the bees.Alarmed, he grabs his spade and smashes the bees as hard as he can, squashing them to death. By this point he is not too worried about the death of bees as he knows what to do by now. He throws them into the lion's cage, because lions eat anything.

Later that day a new lion arrives at the zoo. It wanders up to another lion and says "What's the food like in here?". The other lion says:

"Absolutely brilliant, today we had fish, chimps and mushy bees"

Gastroenterologists have heard every colon/rectum/bile/poop-related joke ad naseum, but I managed to sling a couple of original zingers while being prepped for my colonoscopy.

#1

Me to anesthesiologist: How long have you worked at this clinic?

Anest: About a year. Been with field medical teams my entire career. This is the first time settled down in a clinic...and first time in gastro.

Me: I see. After years in the field, how do like working in an orifice?

Anest.: LOL, no idea how I haven't heard that one yet.

#2

Doctor: We're administering the sedative now. You'll wake up in the recovery bay where I'll brief you.

Me: OK, I'll see you on the outside...[getting groggy]...after you see me on the inside...

Doctor: OK, I'm stealing that one....

They replied, “I ain’t a magician, but I got a couple of twix up my sleeves”

I took it from her and put it up to my ear for a couple seconds, and told her "It says you look very pretty"