How to differentiate ecthyma gangrenosum from cutaneous anthrax?

.

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πŸ“…︎ Nov 12 2021
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Argentina: Suspected case of cutaneous anthrax reported in La Pampa outbreaknewstoday.com/arg…
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πŸ‘€︎ u/thinkingrabid
πŸ“…︎ Nov 19 2021
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Morocco anthrax outbreak: 9 cases of cutaneous anthrax reported in Midelt province. Health officials in Morocco are investigating an outbreak of anthrax in the town of Imilchil in Midelt province, according to a Morocco World News report today. outbreaknewstoday.com/mor…
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πŸ‘€︎ u/Ragnarokcometh
πŸ“…︎ Aug 30 2015
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What's new in the BARDA BAA? Some offtopic, some musings, some on-topic. Bear with me

Hi all.

I've gotten through the text of the BAA and there is a lot to go through this time. This was not a small change, this was not just one or two items being updated. This was the big, wholesale update to the BAA that I've been looking for, and spoiler alert, 9.3 is not the only interesting change.

All of the documents can be found here (Change summaries, special instructions, and the BAA in most of its forms - everything recent is here) SAM.gov

I'm going to ignore 9.3 for now, because we've already talked about it and Golgo with through it point by point in the earlier thread. Read this if you have not, it's good stuff.

This is going to be a long one. Throughout this post, any bold is my addition.

Here are the changes from the change document, just relevant to Amendment 29.

  1. Updates to Area of Interests 1 CBRN Vaccines

>β€’ Revised 1.2 Ebola and Marburg virus
>
>β€’ Deleted 1.3 Antimicrobial Resistant Threats
>
>2. Updates to Area of Interest #2: CBRN Antivirals and Antitoxins
>
>β€’ Revised 2.1 Anthrax Antitoxins
>
>β€’ Revised 2.2 Botulism Antitoxins
>
>β€’ Revised 2.3 Smallpox Antiviral
>
>β€’ Deleted 2.4 Viral Hemorrhagic Fevers Antiviral
>
>β€’ Added New 2.4 Filovirus Therapeutics
>
>3. Updates to Area of Interest #3: Antibacterials
>
>β€’ Deleted 3.1 Develop antibacterial products for post exposure prophylaxis (PEP) and treatment of one or more biothreat pathogens
>
>β€’ Deleted 3.2 Develop new drugs that treat or prevent resistant bacterial infections either alone or in combination with other therapeutics
>
>β€’ Deleted 3.3 Develop non-traditional therapeutics that treat or prevent resistant infections β€’ Added
>
>New 3.1 Develop products for treatment of MDROs and biothreat pathogens
>
>4. Updates to Area of Interest #4: Radiological/Nuclear Threat Medical Countermeasures
>
>β€’ Revised 4.1 Advanced Development of MCMs to treat radiation injury due to acute exposure to ionizing radiation
>
>β€’ Revised 4.2 Blood Products
>
>5. Updates to Area of Interest #5: Chemical Threat Medical Countermeasures
>
>β€’ Revised 5.1 Pulmonary Agents
>
>β€’ Revised 5.2 Opioids
>
>β€’ Revised 5.3 Vesicants
>
>β€’ Revised 5.4 Blood/Metabolic Agents
>
>β€’ **Revised

... keep reading on reddit ➑

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πŸ‘€︎ u/guru_zim
πŸ“…︎ Oct 31 2021
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Had a sore/rash a while back, eventually resolved. Trying to figure out what it could have been.

Hey, this is more of something that happened in the past and has resolved -- I'm just trying to satisfy my curiosity and come up with an explanation. Here's a rough timeline of what happened with the sore/rash:

A roughly round dime-sized area of my arm started developing a cluster of blister-like bumps. They were soft, clear liquid filled, and with no (or very light) pain/discomfort even when touched.

In the next couple days, they slowly broke open and the whole area scabbed over with a dark black scab. Around the edge of the rash was swollen and white, and overall it didn't hurt that much, other than the rawness before it scabbed up.

Over (quite a bit of) time, the scab disintegrated/fell off and I'm left with a scar on my arm, seen here (ignore the pen line on my arm, my camera wasn't wanting to focus and I needed something with contrast).

The only thing I can come up with that fits this progression is cutaneous anthrax, which seems extremely unlikely to me (though maybe not impossible -- I worked at a gas station where farmers/ranchers made up a huge portion of the customer base, which could be a vector). Is there anything else that follows this same set of symptoms? A cluster of pus-filled bumps that burst open and scab over black with white swollen skin around the edges?

(Obviously I should have seen a doctor about it at the time, but money was too tight to afford insurance, let alone seeing a doctor).

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πŸ‘€︎ u/flappity
πŸ“…︎ Nov 02 2021
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The English Sweating Sickness caused five devastating epidemics between 1485 and 1551, with a mortality rate between 30%-50%. Just as quickly as it came, it left the continent, and still remains unidentified by epidemiologists today.

Hi all, just wanted to share a point of significant and weird interest for me in medical history. I have a background in medicine and public health, so epidemics and emerging viruses are some of the great mysteries that I enjoy researching. I hope you enjoy!

It began with a sense of apprehension. The patient would find themselves shaking from an invisible sense of cold, complaining of a headache, and maybe even experience severe pains in their upper limbs and neck. This stage of cycling giddiness, shiving, and pain would slowly progress until the third hour mark, after which the "hot and sweating" stage sets in. From no apparent cause, the patient would rapidly break out into a sweat, and begin complaining of an incredible sense of heat, delirium, rapid pulse, and intense thirst.

If the patient survives from this 3 hour mark to roughly 18 hours after the first onset of symptoms, they then enter the final stages of the illness, or an "exhaustion" phase. During this last phase, there was either general exhaustion and collapse, or an irresistible urge to sleep. Occasionally during these phases, a vesicular (cystic) rash may occur.

Surviving for more than twenty-four hours generally indicated recovery and the perspiration was replaced by high amounts of urination. Remarkably, it seemed to only affect Englishmen, as there were no records of any foreigners being affected on English soil.

This "Sweating Sickness," coined after the symptoms of sweating seen by patients with the illness, was not a disease that conferred resistance to future infection after being exposed. Several people were recorded to experience the Sweating Sickness on multiple occasions before dying, and that testament is confirmed by it's five recurrent outbreaks in 1485, 1508, 1517, 1528, and 1551. In fact, it was not uncommon for patients to have several attacks, and it occurred most often during the summer months.

This disease, oddly, was nearly entirely confined to England, except in 1528-29, where it spread to the European continent in Hamburg, Scandinavia, and eastward to Lithuania, Poland, and Russia. Interestingly, the disease did not spread to France or Italy.

With regard to incubation time (the amount of time needed for the ingested viral particles to reproduce enough in order to elicit symptoms), the most reliable source surrounds the movement of the military and reports of the sickness afterwards. For example, one writer mentions that there were reports of the sweati

... keep reading on reddit ➑

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πŸ“…︎ Mar 19 2021
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SERIOUS: This subreddit needs to understand what a "dad joke" really means.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

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πŸ‘€︎ u/anywhereiroa
πŸ“…︎ Jan 15 2022
🚨︎ report
News - Jul/1/2021: (1) Security official: army reforms & prof. army (2) Economy is growing faster (2) Artsakh minister: infrastructure, roads, demographics (3) Regarding peace agreement (4) Serj's diesel trial (5) NGOs vent (6) Jeb! vs Erdogan (7) IRS stats (8) Less algae in Sevan (9) Skin anthrax

This is your 14-minute Thursday report in 3614 words.

##Armenia responds to Azeri government's statements about the need to sign a peace agreement

Armenia's Parliamentary Chairman of Foreign Relations Committee: Armenia will only sign a comprehensive peace agreement when the Artsakh conflict is resolved.

https://www.panarmenian.net/arm/news/294043/

##update: General Movses "Mosi" Hakobyan was charged with disclosing state secrets

We learned back on May 3 that General Mosi was charged with disclosing state secrets.

NSS reports: Mosi, being the former head of the military control service in MOD, and having access to secret information due to his years of service, disclosed secret information in November.

In particular, it's over long-term weapon and equipment forecast directions, disclosing development plans, disclosing armed forces and civil defense plans, operational programs, combat management, top-secret info about different levels of combat readiness.

He is charged under Article 306.1. The case is sent to prosecutors so they can file court documents.

https://factor.am/388957.html

##Serj's ֏0.5 billion agricultural fuel embezzlement trial resumes

In 2019, former president Serj and the owner of Flash fuel company Barsegh Beglaryan were charged with embezzling agricultural aid in 2013. Two other suspects, one of whom was a key associate who testified against Serj, have since passed away.

The trial resumed today and entered the final stage. Serj has pleaded not guilty.

https://factor.am/389133.html https://factor.am/389166.html https://factor.am/389221.html

##Parliamentary Security Commission chief Andranik Kocharyan about army reforms

Q: can you give details about the proposed army reforms?

Broadly speaking, new weapons, new intellectual management, professional army. What is a "professional army"? It will be revealed when the Government presents that portion of its program and the Parliament forms the relevant commissions. The commission chief will then open the parenthesis.

But even before the elections, the Government had already presented its reform ideas to Parliamentary commissions. MOD Vagharshak began working on it. We need to make very serious personnel reforms in this journey. We have serious gaps here.

What will the education system be, from Pvt to commanders? We know that after t

... keep reading on reddit ➑

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πŸ‘€︎ u/ar_david_hh
πŸ“…︎ Jul 01 2021
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A priest, a pastor, and a rabbit walk into a blood donation clinic.

The nurse asked the rabbit, β€œwhat is your blood type?”

β€œI am probably a type O” said the rabbit.

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πŸ‘€︎ u/snc8698
πŸ“…︎ Jan 29 2022
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I’ve got this disease where I can’t stop making airport puns.

The doctor says it terminal.

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πŸ‘€︎ u/xIR0NPULSE
πŸ“…︎ Jan 28 2022
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Just because it's a joke, doesn't mean it's a dad joke

Alot of great jokes get posted here! However just because you have a joke, doesn't mean it's a dad joke.

THIS IS NOT ABOUT NSFW, THIS IS ABOUT LONG JOKES, BLONDE JOKES, SEXUAL JOKES, KNOCK KNOCK JOKES, POLITICAL JOKES, ETC BEING POSTED IN A DAD JOKE SUB

Try telling these sexual jokes that get posted here, to your kid and see how your spouse likes it.. if that goes well, Try telling one of your friends kid about your sex life being like Coca cola, first it was normal, than light and now zero , and see if the parents are OK with you telling their kid the "dad joke"

I'm not even referencing the NSFW, I'm saying Dad jokes are corny, and sometimes painful, not sexual

So check out r/jokes for all types of jokes

r/unclejokes for dirty jokes

r/3amjokes for real weird and alot of OC

r/cleandadjokes If your really sick of seeing not dad jokes in r/dadjokes

Punchline !

Edit: this is not a post about NSFW , This is about jokes, knock knock jokes, blonde jokes, political jokes etc being posted in a dad joke sub

Edit 2: don't touch the thermostat

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πŸ‘€︎ u/CzarcasmRules
πŸ“…︎ Jan 23 2022
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Blind Girl Here. Give Me Your Best Blind Jokes!

Do your worst!

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πŸ‘€︎ u/Leckzsluthor
πŸ“…︎ Jan 02 2022
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I heard that by law you have to turn on your headlights when it’s raining in Sweden.

How the hell am I suppose to know when it’s raining in Sweden?

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πŸ‘€︎ u/justshtmypnts
πŸ“…︎ Jan 25 2022
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Puns make me numb

Mathematical puns makes me number

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πŸ‘€︎ u/tadashi4
πŸ“…︎ Jan 26 2022
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So my mom is getting her foot cut off today.. (really)

We told her she can lean on us for support. Although, we are going to have to change her driver's license, her height is going down by a foot. I don't want to go too far out on a limb here but it better not be a hack job.

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πŸ‘€︎ u/Slimybirch
πŸ“…︎ Jan 27 2022
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Petition to ban rants from this sub

Ants don’t even have the concept fathers, let alone a good dad joke. Keep r/ants out of my r/dadjokes.

But no, seriously. I understand rule 7 is great to have intelligent discussion, but sometimes it feels like 1 in 10 posts here is someone getting upset about the jokes on this sub. Let the mods deal with it, they regulate the sub.

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πŸ‘€︎ u/drak0ni
πŸ“…︎ Jan 24 2022
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French fries weren’t cooked in France.

They were cooked in Greece.

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πŸ“…︎ Jan 20 2022
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This subreddit is 10 years old now.

I'm surprised it hasn't decade.

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πŸ‘€︎ u/frexyincdude
πŸ“…︎ Jan 14 2022
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Why does Spider-Man's calendar only have 11 months?

He lost May

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πŸ‘€︎ u/Toku-Nation
πŸ“…︎ Jan 26 2022
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When I was a single man, I had loads of free time.

Now that I listen to albums, I hardly ever leave the house.

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πŸ‘€︎ u/porichoygupto
πŸ“…︎ Jan 25 2022
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You've been hit by
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Jan 20 2022
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My 4 year oldest favourit joke, which he very proudly memorized and told all his teachers.

Two muffins are in an oven, one muffin looks at the other and says "is it just me, or is it hot in here?"

Then the other muffin says "AHH, TALKING MUFFIN!!!"

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πŸ‘€︎ u/smoffatt34920
πŸ“…︎ Jan 22 2022
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I'm sick of you guys posting dumb wordplay in here for awards and upvotes.

Don't you know a good pun is its own reword?

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πŸ‘€︎ u/diggitygiggitycee
πŸ“…︎ Jan 21 2022
🚨︎ report
Dropped my best ever dad joke & no one was around to hear it

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies πŸ˜‚

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πŸ‘€︎ u/Vegetable-Acadia
πŸ“…︎ Jan 11 2022
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What starts with a W and ends with a T

It really does, I swear!

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πŸ‘€︎ u/PsychedeIic_Sheep
πŸ“…︎ Jan 13 2022
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My wife left me because I couldn’t stop doing impressions of pasta

And now I’m cannelloni

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πŸ‘€︎ u/bluestratmatt
πŸ“…︎ Jan 23 2022
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Why did Karen press Ctrl+Shift+Delete?

Because she wanted to see the task manager.

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πŸ‘€︎ u/Eoussama
πŸ“…︎ Jan 17 2022
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.
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πŸ‘€︎ u/SupremePalash
πŸ“…︎ Jan 29 2022
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Steve JOBS would have made a better President than Donald Trump

But that’s comparing apples to oranges

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πŸ‘€︎ u/Ok-Ingenuity4838
πŸ“…︎ Jan 22 2022
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I just flew in from Chernobyl

And boy are my arms legs.

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πŸ‘€︎ u/JhopkinsWA
πŸ“…︎ Jan 23 2022
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I have been infected by:

Acinetobacter baumannii Acinetobacter infections Actinomyces israelii, Actinomyces gerencseriae and Propionibacterium propionicus Actinomycosis Trypanosoma brucei African sleeping sickness (African trypanosomiasis) HIV (Human immunodeficiency virus) AIDS (acquired immunodeficiency syndrome) Entamoeba histolytica Amoebiasis Anaplasma species Anaplasmosis Angiostrongylus Angiostrongyliasis Anisakis Anisakiasis Bacillus anthracis Anthrax Arcanobacterium haemolyticum Arcanobacterium haemolyticum infection Junin virus Argentine hemorrhagic fever Ascaris lumbricoides Ascariasis Aspergillus species Aspergillosis Astroviridae species Astrovirus infection Babesia species Babesiosis Bacillus cereus Bacillus cereus infection multiple bacteria Bacterial meningitis multiple bacteria Bacterial pneumonia List of bacterial vaginosis microbiota Bacterial vaginosis Bacteroides species Bacteroides infection Balantidium coli Balantidiasis Bartonella Bartonellosis Baylisascaris species Baylisascaris infection BK virus BK virus infection Piedraia hortae Black piedra Blastocystis species Blastocystosis Blastomyces dermatitidis Blastomycosis Machupo virus Bolivian hemorrhagic fever Clostridium botulinum; Note: Botulism is not an infection by Clostridium botulinum but caused by the intake of botulinum toxin. Botulism (and Infant botulism) SabiΓ‘ virus Brazilian hemorrhagic fever Brucella species Brucellosis Yersinia pestis Bubonic plague usually Burkholderia cepacia and other Burkholderia species Burkholderia infection Mycobacterium ulcerans Buruli ulcer Caliciviridae species Calicivirus infection (Norovirus and Sapovirus) Campylobacter species Campylobacteriosis usually Candida albicans and other Candida species Candidiasis (Moniliasis; Thrush) Intestinal disease by Capillaria philippinensis, hepatic disease by Capillaria hepatica and pulmonary disease by Capillaria aerophila Capillariasis Bartonella bacilliformis Carrion's disease Bartonella henselae Cat-scratch disease usually Group A Streptococcus and Staphylococcus Cellulitis Trypanosoma cruzi Chagas disease (American trypanosomiasis) Haemophilus ducreyi Chancroid Varicella zoster virus (VZV) Chickenpox Alphavirus Chikungunya Chlamydia trachomatis Chlamydia Chlamydophila pneumoniae Chlamydophila pneumoniae infection (Taiwan acute respiratory agent or TWAR) Vibrio cholerae Cholera usually Fonsecaea pedrosoi Chromoblastomycosis Batrachochytrium dendrabatidis Chytridiomycosis Clonorchis sinensis Clonorchiasis Clostridium diff

... keep reading on reddit ➑

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πŸ“…︎ Jun 09 2021
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My 7 year old daughter just told me this one. I'm so proud. What did the duck say when he bought chapstick?

Put it on my bill

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πŸ‘€︎ u/BigRedHusker_X
πŸ“…︎ Jan 26 2022
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So 2 trees got arrested in the town I live...

Heard they've been doing some shady business.

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πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
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What do you call a woman who’s really good at darts?

Amy

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πŸ‘€︎ u/Cinema_King
πŸ“…︎ Jan 29 2022
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No gains
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πŸ‘€︎ u/ridi86
πŸ“…︎ Jan 22 2022
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I was almost upset that my coffee tasted like dirt today

but then I remembered it was ground this morning.

Edit: Thank you guys for the awards, they're much nicer than the cardboard sleeve I've been using and reassures me that my jokes aren't stale

Edit 2: I have already been made aware that Men In Black 3 has told a version of this joke before. If the joke is not new to you, please enjoy any of the single origin puns in the comments

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πŸ‘€︎ u/scarf_spheal
πŸ“…︎ Jan 19 2022
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How eggs-traordinary
πŸ‘︎ 5k
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πŸ‘€︎ u/Rix27_
πŸ“…︎ Jan 21 2022
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Duckduckgo
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πŸ‘€︎ u/findmebatman
πŸ“…︎ Jan 28 2022
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What is the scariest tree?

BamBOO!

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πŸ‘€︎ u/K1ll47h3K1n9
πŸ“…︎ Jan 18 2022
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What is a a bisexual person doing when they’re not dating anybody?

They’re on standbi

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πŸ‘€︎ u/Toby-the-Cactus
πŸ“…︎ Jan 12 2022
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Geometry sucks
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πŸ‘€︎ u/Kash30
πŸ“…︎ Jan 25 2022
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Girlfriend got me good. Never been more proud of her.

Said if she ever hosts a gender reveal party, when it comes time to pop the balloon she'll spray everyone with water.

Gender is fluid.

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πŸ‘€︎ u/Mannheimd
πŸ“…︎ Jan 29 2022
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My ten-year-old daughter came up with this at dinner tonight: What do you get if put a copy of Macbeth on top of a dictionary?

A play on words.

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πŸ‘€︎ u/ah1887
πŸ“…︎ Jan 20 2022
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A queen size statement.
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πŸ‘€︎ u/Flight-less
πŸ“…︎ Jan 22 2022
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Orion's belt
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Jan 25 2022
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Did you know all dogs are made up of only 3 elements?

Calcium, nickel, neon

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πŸ‘€︎ u/redneckvet
πŸ“…︎ Jan 25 2022
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Geddit? No? Only me?
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πŸ‘€︎ u/shampy311
πŸ“…︎ Dec 28 2021
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My son, Luke, loves how I named our kids after Star Wars characters...

My daughter, Chewbecca, not so much.

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πŸ‘€︎ u/andersonfmly
πŸ“…︎ Jan 21 2022
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I wanna hear your best airplane puns.

Pilot on me!!

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πŸ‘€︎ u/Paulie_Felice
πŸ“…︎ Jan 07 2022
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