I was under the impression that beta-importin can bind to an NLS and import the molecule by itself. What's the purpose of alpha-importin then?
Iβm studying the nucleus cytoplasm transport in celular biology, and I donβt quite get wether the importines and exportines are the proteins that join NLS or NES to then join the exportation or importation receptor directly or with an adaptador to create a complex that goes through the pores from or to the nucleus, or if the importines and exportines are the importation or exportation receptors themselves. I know beta importines are receptors so Iβm turning a little crazy. Help please !!!
I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.
Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.
Do your worst!
I'm surprised it hasn't decade.
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies π
It really does, I swear!
Theyβre on standbi
Buenosdillas
