Diabetes insipidus Puns

So I decided to do Intense Cycling. I used to do like 10km increasing the KM by day for a period of 6 months. One day I just woke up feeling thirsty. I thought ooh well I just did bike cycling that day my body was really dehydrated. The excessive thirst got intense and with this came with peeing a lot. I used to drink 10 liters a day!!! Until one day a nurse friend told me it's abnormal. So I decided to be screened in the hospital. Most of the Blood Sugar test came out normal. Then the endocrinologist suggested I do ADH test. The results came back and my ADH hormone was low. I did an MRI scan to check on whether I had any tumor which turned out I don't have. I did a bunch of blood sugar, urinalysis and kidney test and all of them turned out to be fine. Since then I have been living with this rare condition taking Desmopressing Nasal Spray as a treatment.
Has anyone had this condition. I just want to really understand why mine came after an Intense Bike cycling.

37M, had COVID in April 2021 (a mild case, recovered at home, SpO2 never dropped below 96%).

Has anyone here been tested for diabetes insipidus?

I'd be interested to know, because I've been struggling with GI issues since I had COVID back in April, specifically hard stools (which, apart from being annoying, also cause other problems). Prior to having COVID, I also experienced this from time to time, but it seems like COVID made it waaay worse. I'm not backed up: I have 2-3 bowel movements per day. My transit time's good (food seems to go through me within 24 hours, judging from some home testing I've done with eating pumpkin seeds), so it's not getting stuck along the way - it's just inexplicably hard.

I've also been experiencing slightly lowered blood pressure (used to be 120/80, now 105/68 on average), which causes me fatigue and light-headedness at random times of the day. I have more skipped heart beats nowadays than pre-COVID (pre-COVID I may have noticed it once a week, but now it happens 5-10 times per day).

Testing I've undergone: ECG/exercise stress test/Holter monitor/24-hour ambulatory blood pressure monitoring, abdominal ultrasound, and many, many blood tests - all normal. I had a colonoscopy last year (2020) that was normal, so it wouldn't be anything structural. Fiber supplements and probiotics do nothing for me. Prebiotics (inulin specifically) seemed to help a little for a while, but it stopped helping within a week or two for some reason.

Recently I've been noticing that I'm thirsty quite frequently and my eyes are continuously dry and red, but last week I had a 24-hour urine test to check my sodium levels, and my urine output was 2.2 litres (and that was a normal day, drinking and peeing as much as I normally do), which implies that I was getting more than 8 glasses' worth of liquid in an average day. Sodium and creatinine levels were totally normal. I've had glucose and HbA1C levels checked a month or two ago and they were normal so I know it's not type 1/2 diabetes.

Then it got me thinking: what if there's some connection between the dehydration (perhaps from excess fluid loss), skipped heart beats (possibly due to loss of electrolytes), low blood pressure (from low fluid volume in my system), and hard stools (dehydration)?

I recently discovered diabetes insipidus, a rare condition which can be caused by nervous system or kidney problems (two areas COVID can often damage, fr

No its not a problem of dehydration, i take my electrolytes, calcium, vit D, fruits, no salt, no sodium, no spicy foods. But i have a serious problem with cognition and subtle underlying confusion that never ends, vision is darkned, ringing in both ears, apathy, and above all declined cognitive abilities in every respect. Have you ever experienced that... please help I tried everything for three years know...

I can't seem to find answers on Google or anywhere online: I searched for this subreddit on Reddit and have just found it. I hope you may be able to help me understand.

If you gave Desmopressin (DDAVP) which is an antidiuretic, to a healthy individual, would it change their desire to drink fluid? if so, how notably? Please understand I don't know a lot about this condition.

It is used as a trial based system to diagnose Diabetes Insipidus in dogs. I want to know what the "normal" reaction would be to differentiate it from the change you'd see in a dog that actually has the disease. I'm lacking the understanding of how it would affect a person or animal that did not have the disorder vs one that does. I'm doing a trial on my dog right now as per vet recommendation and I just am a little lost on what would be a normal reaction vs an abnormal one. Thank you.

I go to school for pharmacology and my midterm is wednesday </3

below is what it says in my study material (which I can't wrap my head around)

https://preview.redd.it/jbrinn3sj7181.png?width=746&format=png&auto=webp&s=f929c7d97f13ba8fe2afd90470460b2d4ab1a321

Hello I'm an 18yo white Male about 250 pounds 5"9 with Diabetes Insipidus which I am taking medicine for along with concerta and some thyroid medicine. And have never smoked, drank, or gotten high

I've been told by my family forever that alcohol isn't good to drink with my medical condition sense it has something to do with hormones and my liver or kidneys. If I'm being honest I still dont understand a lot of it and would love if anyone can help me with that too. But I've been curious lately about if I was to smoke weed or anything relating to that, would it effect me any, and how would it affect me.

I don't plan on smoking it, but if I was offered it ever, it would be nice to know if I can or not

Sorry for bad grammar

It's a somewhat rare condition and has nothing to do with insulin levels, but I thought I'd check and see. I just got a consult date today, but I'm concerned I may be denied due to this condition. My immediate concern is fluid intake post surgery and that I will end up dehydrated.

I’m new here! I was told that you could potentially help. If this is not the right please point me in the right direction. I was recently diagnosed with central diabetes insipidus. I went into a state hypernatremia and was in ICU for a week and my bodies sodium is over correcting itself and I suffer with extreme nausea daily. I take my daily dose of medication but still suffer from thirst and excessive urine outtakes. What can I do to live more of a functional lifestyle and avoid another visit to the hospital :(

Help please! 🙏🏻

Hi everyone. My cat has diabetes insipidus which basically means he can’t retain water and therefore urinates A LOT (his medication helps but he definitely pees more than the average cat). Right now he’s using pine pellet litter because it doesn’t get soupy after peeing.

Wondering if the litter robot would work for my cat? If he pees a lot will the litter still clump and cycle out? Or will it just lead to a soupy tray at the bottom….

How common is it to get diabetes insipidus if you haven’t been on lithium very long? I just started lithium and I’ve been urinating very frequently and been very thirsty and I read this can be a sign of diabetes insipidus from lithium and should talk to my doctor about it, but usually this happens after years of lithium use..I’m very bummed because lithium works very well for me and I really want to stay on it. I haven’t had labs yet to test my kidneys. I have a doctors appointment on Wednesday.

Note: I was peeing a lot before starting lithium so I suspect something was already wrong but since starting it I have been peeing A LOT more.

I (23, M, White) have been suffering from excessive urination and thirst for maybe about 3 years (maybe 4) now. To get an idea of how bad it is, I recently took a 24 hour urine test, and completely filled up 3 jugs and some of a 4th. It's so bad that it prevents me from getting to sleep (especially combined with the thirst), which has caused me to only be able to go to bed when I'm excessively tired (I'm talking 4 or 5 in the morning) in order to not be constantly waking up to pee and drink, and thus destroyed what semblance of a sleep schedule I may have had. I sometimes have a full stream every 5-10 minutes, though 20 minutes is more common. It's worse at night, but still bad during the day, and negatively impacts my quality of life. The urination still happens if I dehydrate myself (albeit less of a full stream), so I don't think it's because of how much I drink.

I've been seeing an endocrinologist and she seems to think that Diabetes Insipidus is the only endocrine explanation for those symptoms. But she's been testing my blood for over a year, and my hormones are completely normal, so she thinks it's likely not Diabetes Insipidus. I'm still getting an MRI of my pituitary just in case, but so far it seems like that's not the cause, and that makes me nervous. I do have an appointment with a Urologist, but my own research hasn't found anything that makes sense in terms of Urology. Everything I've found online that might cause excessive urination doesn't fit my symptoms, and even worse, doesn't account for the thirst at all. I'm scared that we're not going to figure out the cause of this, and that will destroy my ability to function.

To give as much background as I can, I'm about 5' 8'', and I currently weight around 205 pounds, but that's after losing a lot of weight. 5 months ago, I weighed closer to 250 and had terrible eating habits. I don't have diabetes, but I do have insulin resistance (as discovered by the aforementioned endocrinologist) and am currently taking Metformin for it. I was also recently prescribed Haloperidol and Lamotrigine for mental health reasons, but that's just from the last few months. I have no allergies, have never had surgery, and am generally pretty healthy outside of being overweight and out of shape. When I was in middle school, I had to go on growth hormone and some other shot (I don't remember what it's called) because my growth plates were closing too quickly. Not sure if that's connected to this, but I figure it's at

A good friend of mine got diagnosed with diabetes insipidus and she's been having serious salt cravings due to an additional lack of cortisole (i'm pretty new to this, but i think it's more due to adrenal insuffieciencies than diabetes? If anybody knows it would be super helpful).

Does anyone know any good alternatives and/or has tried any of the hacks on thebinternet like lemons/limes?

I'm a PGY3 IM currently on an outpatient endo rotation and was seeing a consult for diabetes insipidus from a midlevel. The guy initially presented to their office with polyuria and polydipsia. They got initial labs and the A1c: >10. They started him on metformin and sent him on his way. A few weeks later, he called their office back to tell them his symptoms were still present but improved. The midlevel made a big brain move to discontinue the metformin and start desmopressin. The patient called them a week later saying his symptoms got worse and was told to double up on his desmopressin. He was subsequently referred to endo for further workup for his "DI".

u/avneis

[15 year old male] My lower back area feels like there is discomfort. My diet consists high in protein and sodium which led to my kidneys hurting a lot in the past. Excessive thirst and instantly urinating the water with dry lips and fingers. This all started because I decided to eat a lot of cheez its with a very high protein diet for a few days. This was 7 days ago and it suddenly happened. My blood gluocse is 83 for fasting and 92 for eating so it is not diabetes according to my doctor. My doctor thinks im crazy and is sending me to a counselor and a Otolaryngologist when my kidneys are the real problem here. My dad threw a tantrum and punched the wall 2 times because I kept asking him about my symptoms. At the time I am writing this I just drank a entire cup of water and I still feel thirsty. Im thinking about suicide, I've had enough of this and im sick of myself.

So last month Gin, my almost 10 year old American Foxhound was formally diagnosed with central diabetes insipidus (CDI). She had been displaying symptoms for a while, but they were masked by other issues and it took time to reach the diagnosis. Here is a little update and some more detailed background on the condition.

Though it is a rarer form of diabetes for dogs, a more common diabetes is diabetes mellitus. That is the one that impacts glucose (sugar) levels, while insipidus does not. Diabetes insipidus is caused by an inadequate production of a hormone, antidiuretic hormone (ADH). When dogs are lacking this hormone it causes them to have excessive drinking, urination, extremely dilute urine, etc., which as you can tell are very common symptoms of a variety of different canine diseases.

More specifically, Gin is diagnosed with central diabetes insipidus (CDI) rather than nephrogenic diabetes insipidus (NDI). Central is sometimes caused by tumors in the brain, brain trauma, birth defects, and really just unknown causes. Her kidneys were ruled out as the problem as we ran multiple kidney tests and ultrasounds. We also now believe her physical tremors/gradual weakening of the rear legs could have some relation to her CDI, especially if there are tumors involved, we did full spinal x-rays and have no evidence of physical issues. I do know for sure she has not had any recent head/brain trauma but since she came to be at 4.5 years of age it'd be hard to know for sure.

Diagnosis for CDI is done after testing for other common diseases, kidney, liver, Cushing's, etc. and is done by conducting a water deprivation test. I could chose to elect and do more tests to confirm the presence of the tumors but it wouldn't change anything. It's an easy condition to manage and while it's more rare, I am somewhat glad it isn't the sugar kind. Checking insulin/sugar levels and providing injections is not part of out treatment for the disease.

We are on our first dosage level of desmopressin, a drug used to treat CDI. We are doing the pill form and currently she gets .1mg every 12 hours - we plan to discuss upping this a little bit due to 2 urinary accidents since starting the drugs but she has improved greatly and her symptoms are more manageable and less severe. Overall, Gin & I are much happier now that her condition is better managed. Unfortunately, she can never be given night time free roaming again because she may still have urinary accidents, that is

title

Is there anyone here that has gone through WLS with DI (Diabetes Insipidus)? This first week now being out of the hospital and off an IV. I’m finding it harder to be satisfied with fluid intake. I feel more dehydrated than before which is cascading into other thing (mood swings, feeling weak, regretting the surgery) if there is anyone out there that has gone through this let me know how things went for you. I’m am currently at day 5 Post-Op.

Title is self explanatory but I have seen few videos where he just touches upon DI however I'm looking for a more full fledged explanation.

Hello, I hope this is the right place for this... We've been burning through large tubs of litter almost once a week because of how much one of my cats urinates. He is on medicine, which helps the matter somewhat (volume wise at least) but we are waiting on the prescription order to come in on Tuesday now. His litter always turns to sticky mud when he uses it, while my other two cats just clump normally... I would like any advice on how to save litter, how to prevent this mud from happening, how to clean muddy litter out from litter grates or scoopers, anything that you can think of is greatly appreciated. Whatever can make dealing with his litter easier is worth commenting. We have tried numerous brands of clumping litter and I don't think non clumping would be a good idea because of the smell (and the volume of urine he produces, last we tried non clumping it turned into a soupy mess.)

Can anyone explain why nephrogenic diabetes insipidus is treated with thiazide diuretics?

Thiazide diuretics decreases Na reabsortion. So, water reabsorption will be decreased too, since it follows Na. But isn't the goal to increase water reabsorption in diabetes insipidus?

Anyone here have diabetes insipidus from taking lithium? What is it like for you? I had it with my last pregnancy and now my doc thinks I might have mild DI all the time and I'm just more sensitive while pregnant.

In your experience, where's the line between being thirsty from lithium vs being thirsty from DI? Are there risk factors that exaggerate symptoms? Is an endocrinologist the best specialty doc to follow up on lithium DI?

Eta: specifically asking about diabetes insipidus and not the insulin-related diabetes mellitus.

16m I had a tumor in my suprasellar area. I was given high dose steroids for 3 months and My endo was really bad and misdiagnosed me with adrenal insufficiency and hypothyroidism. He was giving me meds that would eventually just atrophy my adrenal glands and suppress my pituitary.

I have though undetectable LH and fsh. I'm also diagnosed with diabetes insipidus which is the most annoying thing I have. I was wondering if there's a chance I may not actually have DI and something caused my ADH to be suppressed in the beginning and i am just suppressing it further by taking desmopressin.

I've been having symptoms of diabetes insipidus but I don't have extreme thirst (I'll say just a little more than normal). I had an abdominal TAC yesterday that showed problems in my kidneys and also had an MRI that showed a microadenoma in my pituitary gland. Years ago I checked my T levels and they were low, as well as my T3. Can all this be related?

Does anyone know how Conn syndrome can cause diabetes insipidus?