Valneva and Pfizer Report Further Positive Phase 2 Results, Including Booster Response, for Lyme Disease Vaccine Candidate: targets the outer surface protein A (OspA) of Borrelia burgdorferi... and covers the six OspA serotypes that are prevalent in North America & Europe pfizer.com/news/press-rel…
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πŸ‘€︎ u/shallah
πŸ“…︎ Oct 01 2021
🚨︎ report
The Brilliance of Borrelia: Mechanisms of Host Immune Evasion by Lyme Disease-Causing Spirochetes - Lyme disease has become the most common vector-borne illness in the northern hemisphere. The causative agent, Borrelia burgdorferi, is capable of establishing a persistent infection within the host. pubmed.ncbi.nlm.nih.gov/3…
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πŸ‘€︎ u/StcStasi
πŸ“…︎ Aug 19 2021
🚨︎ report
Antibiotics | Identification of Essential Oils with Strong Activity against Stationary Phase Borrelia burgdorferi

This article discusses the Stationary Phase that Borrelia enters. This phase occurs after the log or exponential phase (active infection). It appears that the antibiotics that may have arrested the log/exponential phase may not treat the Stationary Phase. The article discusses this.

https://www.mdpi.com/2079-6382/7/4/89

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πŸ“…︎ Jul 27 2021
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Azlocillin can be the potential drug candidate against drug-tolerant Borrelia burgdorferi sensu stricto JLB31 nature.com/articles/s4159…
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πŸ‘€︎ u/SftwEngr
πŸ“…︎ May 20 2021
🚨︎ report
I was diagnosed Lyme Borrelia burgdorferi IgG

Hi,

Today I was diagnosed with Lyme Borrelia burgdorferi IgG (result: positive). I guess I was infected 5-6 months ago. I didn't notice any red circles.

My symptoms are:

  • shortness of breath
  • red and dry eyes
  • light headache (very often)
  • tiredness (very often)
  • light pain in the leg joints (not all the time)
  • short memory
  • decreased eloquence, decreased speed of speech
  • hand numbness (only sleep time and rare)
  • decreased libido
  • problem with urination

I read here your posts about your cases and I am not very optimist what I found. However I just want to ask few questions.

My GP told me today that I already have antibodies and I don't need antibiotics. At least she arranged an appointment with infectologist tomorrow for consultation, lets see what she says. So is GP right that I don't need antibiotics if this disease last for 5-6 months and I already have antibodies? And if for example this disease I have lasted for 1-2 or maybe 3 years (I am still not sure when I got it), do I need antibiotics then?

As per my symptoms I have, I guess this disease should last 5-6 months, otherwise I should have much stronger symptoms or much early symptoms. Am I right?

Thank you very much for an answers.

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πŸ‘€︎ u/GZalias
πŸ“…︎ Jan 27 2021
🚨︎ report
Hey guys, how to kill borrelia burgdorferi? I’m infected for years with zero ability to fight it in my body.

It produces disease called Lyme and messes heavily with persons neurotransmitters (similar to other bacteria?) causing all kinds of debilitating effects.

I’m biologist myself, but focus on genome data analysis. Although with limited practical knowledge, I am aware of cas9 systems ability to disrupt DNA at specific locations and wonder if there is a cas9 analog for bacterial targets? How feasible it is to make some kind of borrelia β€œDNA shredder” and apply it in vivo? I could gather funds if you to 10mil/year for such project but am 95% sure it’s not feasible, please prove me wrong. Thanks guys.

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πŸ‘€︎ u/Nevermindever
πŸ“…︎ Aug 26 2020
🚨︎ report
Borrelia Burgdorferi Biofilm - Live Microscopy Video youtu.be/fJqTDnbL7Yo
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πŸ‘€︎ u/Nevermindever
πŸ“…︎ Jun 02 2020
🚨︎ report
[Article] mRNA transcript distribution bias between Borrelia burgdorferi bacteria and their outer membrane vesicles

https://doi.org/10.1093/femsle/fny135

https://academic.oup.com/femsle/advance-article-abstract/doi/10.1093/femsle/fny135/5017443?redirectedFrom=fulltext

Thanks in advance!

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πŸ‘€︎ u/Blanq_Winq
πŸ“…︎ Jun 05 2018
🚨︎ report
Dumb question on Borrelia Burgdorferi

Are Uworld and FA going against each other here?

Uworld says Borrelia isn't typically visualized on microscopy while FA says Borrelia is the only spirochete that can be visualized using aniline dyes in light microscopy due to size. What do I go by here?

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πŸ‘€︎ u/projectgetbetter
πŸ“…︎ Dec 02 2020
🚨︎ report
Functional and Genomic Architecture of Borrelia burgdorferi-Induced Cytokine Responses in Humans. ncbi.nlm.nih.gov/m/pubmed…
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πŸ‘€︎ u/applextrent
πŸ“…︎ Dec 07 2018
🚨︎ report
"We have never in the past five years a single MS patient, a single ALS patient, a single Parkinson's patient who did not test positive for Borrelia Burgdorferi. Not a single one." ~ Dietrich Klinghardt, MD (From the Award-Winning Documentary "Under Our Skin: The Untold Story of Lyme Disease") underourskin.com
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πŸ‘€︎ u/ringhopper
πŸ“…︎ Mar 27 2018
🚨︎ report
Does Lyme testing ELISA, Western Blot recognize other strains of Borrelia other than B.Burgdorferi like B.Afzelli and B.Zarinii etc.?

Basically what the title says. Since these tests look for antibodies for B.Burgdorferi does it cause false negatives for people infected with other strains?

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πŸ‘€︎ u/furybury66
πŸ“…︎ Jan 15 2020
🚨︎ report
Borrelia burgdorferi peptidoglycan is a persistent antigen in patients with Lyme arthritis pnas.org/content/early/20…
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πŸ‘€︎ u/baconn
πŸ“…︎ Jun 18 2019
🚨︎ report
Borrelia burgdorferi found in multiple organs in autopsy of woman with well documented Lyme Disease despite 16 years of antibiotic treatment mdpi.com/2079-6382/8/4/18…
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πŸ“…︎ Oct 15 2019
🚨︎ report
Repurposing disulfiram (Tetraethylthiuram Disulfide) as a potential drug candidate against Borrelia burgdorferi in vitro and in vivo biorxiv.org/content/10.11…
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πŸ‘€︎ u/sburgess86
πŸ“…︎ Nov 16 2019
🚨︎ report
Do we know if Disulfiram works against borrelia strains other then burgdorferi ?

I thought I heard in some YouTube interview with one of the doctors it would be effective against all Borrelia strains but am not 100% sure on this.

You would expect so, the antibiotics work against all the strains the same.

Really hope so, because I have the coriaceae strain.

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πŸ‘€︎ u/Dr-Maximum
πŸ“…︎ Nov 23 2019
🚨︎ report
ifferences in Genotype, Clinical Features, and Inflammatory Potential of Borrelia burgdorferi sensu stricto Strains from Europe and the United States wwwnc.cdc.gov/eid/article…
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πŸ‘€︎ u/liketosee
πŸ“…︎ Apr 07 2016
🚨︎ report
New Research: Robust interferon signature and suppressed tissue repair gene expression in synovial tissue from patients with post-infectious, Borrelia burgdorferi-induced Lyme arthritis researchgate.net/publicat…
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πŸ‘€︎ u/rspeed
πŸ“…︎ Dec 12 2018
🚨︎ report
Stationary Phase Persister/Biofilm Microcolony of Borrelia burgdorferi Causes More Severe Disease in a Mouse Model of Lyme Arthritis: Implications for Understanding Persistence, Post-Treatment Lyme Disease Syndrome (PTLDS), and Treatment Failure discoverymedicine.com/Jie…
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πŸ‘€︎ u/SftwEngr
πŸ“…︎ Apr 25 2019
🚨︎ report
Researchers at Johns Hopkins Identify Essential Oils with Strong Antimicrobial Activity Against Borrelia burgdorferi, the Causative Agent of Lyme disease mdpi.com/2079-6382/7/4/89
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πŸ‘€︎ u/dem202020
πŸ“…︎ Feb 11 2019
🚨︎ report
Another 20 year old photo of a fluke at lower right, birthing a worm or is this the borrelia burgdorferi? Microfilarial
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πŸ‘€︎ u/nelst
πŸ“…︎ Aug 20 2019
🚨︎ report
I Have Disseminated Borrelia Burgdorferi and Babesiosis; Will Cannabis Help?

Long story short, I was diagnosed with three infections around a year ago. Misdiagnosed by incompetent doctors and inaccurate diagnostics for more than three years. I've taken antibiotics which has SIGNIFICANTLY helped my neurological symptoms but the pain remains, at times excruciating. Almost all of my joints severely hurt as well as my bones and muscles.


As a teenager I smoked and I never really liked the high, I honestly hated it. Couple that with my cognitive and memory impairment from the infection and I was no different than a sloth.


I'm 22 years of age now and I need something, anything to relieve this pain. HOWEVER, I do not want to completely suppress my immune system. I know THC suppresses the immune system and in studies this is well know. It is a potent anti-inflammatory. I'm more interested in CBD for my nerve and joint pain.


KRATOM has also kept me interested.

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πŸ‘€︎ u/birthdaysuit11
πŸ“…︎ Oct 09 2016
🚨︎ report
Identification of Essential Oils with Strong Activity against Stationary Phase Borrelia burgdorferi mdpi.com/2079-6382/7/4/89
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πŸ‘€︎ u/TheSwitchBlade
πŸ“…︎ Dec 25 2018
🚨︎ report
Drug Combinations against Borrelia burgdorferi Persisters In Vitro: Eradication Achieved by Using Daptomycin, Cefoperazone and Doxycycline pdfs.semanticscholar.org/…
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πŸ‘€︎ u/BitmexRanger
πŸ“…︎ Aug 22 2018
🚨︎ report
Persisting atypical and cystic forms of Borrelia burgdorferi and local inflammation in Lyme neuroborreliosis ncbi.nlm.nih.gov/pmc/arti…
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πŸ‘€︎ u/BitmexRanger
πŸ“…︎ Jan 15 2019
🚨︎ report
"We never had in the last 5 years a single MS patient, a single ALS patient, a single Parkinson's patient who did not test positive for Borrelia burgdorferi. Not a single one." - Dietrich Klinghardt, MD (From the Oscar Nominated Flick "Under Our Skin: The Untold Story of Lyme Disease") reddit.com/r/conspiracy/c…
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πŸ‘€︎ u/rotoreuters
πŸ“…︎ Aug 08 2018
🚨︎ report
Amblyomma americanum (Acari: Ixodidae) Ticks Are Not Vectors of the Lyme Disease Agent, Borrelia burgdorferi (Spirocheatales: Spirochaetaceae): A Review of the Evidence | Journal of Medical Entomology academic.oup.com/jme/arti…
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πŸ‘€︎ u/jessrichmondOUP
πŸ“…︎ May 08 2018
🚨︎ report

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