Pyloric Antrum Puns

Hello!

During the summer of 2017, I partied hard: all day drinking, multiple days in a row. I was aged 27 and thought I could party like I did at 21. One morning, after sleeping on the floor, I woke up with a dull pain that would stay with me for literally years. The dull pain was a source of health anxiety and prompted me to go for multiple GI tests: HIDA scan, CT scan, ultrasounds. I was worried it could be my pancreas, gallbladder or liver because the pain was just slightly on the right side

all tests came back normal. doctor prescribed me omeprazole. I gradually accepted the new norm and figured out certain triggers (coffee on an empty stomach, alcohol on an empty stomach, chocolate on an empty stomach, spicy food, fizzy drinks - basically all the fun things in life). During this time, I also developed IBS and experienced worsening health anxiety. I was lucky to have met a super kind gf by that point who was patient with my flare ups

about a year ago I decided to get to the bottom of my IBS (no pun intended). I did a York food intolerance / allergy test, multiple THRIVA blood tests, healthpath microbiome test and discovered i was super low on B12, vitamin D and intolerant to gluten. I'd also nuked my gut biome via antibiotics

I began supplementing with liquid b12 taken sublingually (this is important because my gut is/was poor at absorbing b12) and I cut out gluten (no beer and no pasta agghhhhhhh)

I switched to low acidity coffee: NATURAL PROCESS COFFEE

I started making my own bone broth and supplementing with hydrolysed collagen

I never drink alcohol or coffee on an empty stomach. throughout all of this I was aware that these were trigger foods but I refused to give them up completely because i'm stubborn like that

and here is the part i don't understand: I started supplementing with various probiotics and prebiotic fibres to assist my gut microbiome: Partially hydrolyzed guar gum (PHGG), various fructo oligosaccharides (FOS but not GOS), psyllium husk - strangely, these appeared to make the biggest difference. it's as if drinking these on any empty stomach every morning help to restore the stomach lining and upper intestinal tract. Having higher levels of B12 circulating in my body probably helps the healing process too and avoiding gluten

I have been to a few weddings this summer and drank a great deal of red wine (I avoid beer) and I'd expect the first delicious gulp to cause the normal dull pain but to come but to my amazement it does

Diagnosed today with EOE . I’ve had pain in upper abdomen for 2 months . Radiates up under right ribs , sometimes to flank ? Under armpit kind of .

I’ve never known to have any esophageal issues .

Do you think the EOE can cause pain in abdomen ? Or is this more gastritis related . Gastritis was in antrum near pyloric area .

I am on nexium 20 twice a day . Was on protonix before for GERD issues .

What can I do to treat the EOE . Any hints or advice ?

Hi guys. Being the infinitely curious person that I am, deciding to ask this here for any insight while I wait for biopsy results and further doctor visits.

22F. Caucasian. 5'2", 130?ish lb. Don't smoke, and only drink/take weed like 1-2 times a month socially. Currently taking Vitamin D3 1000 IU/day, Vitamin B12 500mcg/day, Buspirone 10mg/day, Mesalamine Oral 4 tabs/day, Microgestin 1.5mg 1 tab/day, IBGuard 2 capsules/day, Lansoprazole 15mg/day and night.

As for previous medical history, I had pyloric stenosis as an infant. Diagnosed with ulcerative proctitis in March 2020 that's currently in remission. Have mild-moderate scoliosis. Diagnosed somewhat recently (around November 2021) with IBS and possibly GERD as well.

So for many months now, I've been dealing with a ton of weird medical issues that don't seem to be adding up. Back in April 2021, I experienced like once or twice dark coca-cola colored urine without any UTI-like symptoms or issues. Brushed it off as dehydration until September 2021 when it came back much more frequently. Ruled out dehydration, UTI, even porphyria; still trying to figure out wtf is going on with that. Figured I'd mention it here w/ my other symptoms as I don't know yet if they're related or not. Will be seeing a nephrologist next week to get that checked out.

Besides some scary dark pee, around April 2021 I finally went to my PCP to figure out why I was having acid reflux so often. At that point, I was having it every day, throughout the day, no matter what I ate or drank. This was happening for months prior to April and were getting progressively worse until that point. Was prescribed the lansoprazole 15mg in the morning and this completely helped my acid reflux until around September 2021.

From then on, reflux started showing up again despite the lansoprazole dosage. My GI told me to start taking my lansoprazole at night as well, but that hasn't helped. In addition, bloating became more frequent. The most worrying symptom was a very specific uncomfortable pain/tenderness in my right upper quadrant. I think the specific area is around/near my duodenum??

It's a very specific kind of uncomfortable tenderness, it almost feels like the area is bruised, or if someone was pinching the area pretty hard. Sometimes the pain would radiate to my back, where it'd be more of a burning ache. I've experienced this pain for much longer than anything else, but it was really intermittent, it would come and go very infrequently. It was

Hi all,

About a week or two back I made a post about my struggles with LPR and I offered some tips and advice by sharing some information with the hopes of helping others because they seemed to have been working well for me. I also made some comments about being cautious with use of PPIs and I promised that I would deliver some scientific evidence as a scientists who is devoted to promoting human wellness and health. There was a mix of positive feedback and some fellow Redditors who seemed to be a bit upset about my take on PPIs.

None of the advice and scientific studies I discuss are intended to be utilized in place of medical advice from a healthcare professional. I encourage you to reach out to an ENT and make sure you are getting good care for your condition along with a proper diagnosis.

I intend for this to be purely educational and also to allow you to make informed choices and decisions about the use of PPI therapy. There are perhaps a good number of ENTs who are hesitant about the use of PPIs for some of their patients as a long-term therapy and I hope that this post and these scientific studies and meta-analysis studies will make you a better informed patient about commonly used therapies for GERD and LPR and also about the risk of developing Barret’s Esophagus and Esopghageal Adenocarcinoma.

I will break this down into a few parts below: 1) Evaluating PPI use and Alzheimer’s/ Dementia association 2) Evaluating use of PPIs and risk of Barret’s Esophagus (BE) and Esopghageal Adenocarcinoma (EAC) 3) Pathophysiology of BE metaplasia and EAC 4) Role of gastrin and the CCK2R receptor involved in disease and PPI use leading to elevated gastrin levels.

As I promised, sources are associated with my review below. I hope you enjoy this :)

This was the original post: https://www.reddit.com/r/GERD/comments/nxb0eu/input_life_style_changes_from_a_scientist_on_lpr/?utm_source=share&utm_medium=web2x&context=3

​

(A) EVALUATING PPI USE AND RISK OF ALZHEIMER’S (AD) AND NON-ALZHEIMER’S DEMENTIA

Study Objective: To investigate the association between the use of PPIs and an increasing risk of incident AD or non-AD dementias.

Rationale: Some experimental and clinical studies in recent years have found that proton pump inhibitors (PPIs) are associated with a

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

Do your worst!

I'm surprised it hasn't decade.

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂

It really does, I swear!

They’re on standbi

I thought it was the Cardia instead of the Antrum.

https://preview.redd.it/el3f86drjbs41.png?width=505&format=png&auto=webp&s=44fd8b88189d998c65034a226ed5be3293a642fa

Pilot on me!!

Nothing, he was gladiator.

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

When I got home, they were still there.

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

I won't be doing that today!

[Removed]

You take away their little brooms

This morning, my 4 year old daughter.

Daughter: I'm hungry

Me: nerves building, smile widening

Me: Hi hungry, I'm dad.

She had no idea what was going on but I finally did it.

Thank you all for listening.

There hasn't been a post all year!

Why

It’s pronounced “Noel.”

After all his first name is No-vac

What, then, is Chinese rap?

Edit:

Notable mentions from the comments:

• Spanish/Swedish/Swiss/Serbian hits

• French/Finnish art

• Country/Canadian rap

• Chinese/Country/Canadian rock

• Turkish/Tunisian/Taiwanese rap

There hasn't been a single post this year!

(Happy 2022 from New Zealand)

Nothing, it just waved

Him: I can explain everything!

(It's his best joke yet I think)

Bob

So that I could frequently say, "I am going to walk 5 miles now."

Edit: My most popular post on Reddit! 😀 Thank you for the awards.

Just to clarify, 12345678

Me grabbing a soda from my (what I thought was) half full 12pk...

Notices there's only 2;

Me: "Awe man... This is a damn bird box!" Her: "What the hell does that mean?!" Me: (Pulls both cans out & shows them to her) "It's only got Toucans."

I'm not ashamed to admit the look on her face was glorious.

I was just sitting there doing nothing.

Hi all,

About a week or two back I made a post about my struggles with LPR and I offered some tips and advice by sharing some information with the hopes of helping others because they seemed to have been working well for me. I also made some comments about the being cautious with use of PPIs and I promised that I would deliver some scientific evidence as a scientists who is devoted to promoting human wellness and health. There was a mix of positive feedback and some fellow Redditors who seemed to be a bit upset about my take on PPIs.

None of the advice and scientific studies I discuss are intended to be utilized in place of medical advice from a healthcare professional. I encourage you to reach out to an ENT and make sure you are getting good care for your condition along with a proper diagnosis.

I intend for this to be purely educational and also to allow you to make informed choices and decisions about the use of PPI therapy. There are perhaps a good number of ENTs who are hesitant about the use of PPIs for some of their patients as a long-term therapy and I hope that this post and these scientific studies and meta-analysis studies will make you a better informed patient about commonly used therapies for GERD and LPR and also about the risk of developing Barret’s Esophagus and Esopghageal Adenocarcinoma.

I will break this down into a few parts below: 1) Evaluating PPI use and Alzheimer’s/ Dementia association 2) Evaluating use of PPIs and risk of Barret’s Esophagus (BE) and Esopghageal Adenocarcinoma (EAC) 3) Pathophysiology of BE metaplasia and EAC 4) Role of gastrin and the CCK2R receptor involved in disease and PPI use leading to elevated gastrin levels.

As I promised, sources are associated with my review below. I hope you enjoy this :)

This was the original post: https://www.reddit.com/r/GERD/comments/nxb0eu/input_life_style_changes_from_a_scientist_on_lpr/?utm_source=share&utm_medium=web2x&context=3

​

(A) EVALUATING PPI USE AND RISK OF ALZHEIMER’S (AD) AND NON-ALZHEIMER’S DEMENTIA

Study Objective: To investigate the association between the use of PPIs and an increasing risk of incident AD or non-AD dementias.

Rationale: Some experimental and clinical studies in recent years have found that proton pump inhibitors (PPIs) are associated wi