Neuromodulation Puns

Burke, M.J., Romanella, S.M., Mencarelli, L. et al. Placebo effects and neuromodulation for depression: a meta-analysis and evaluation of shared mechanisms. Mol Psychiatry (2021).

DOI: https://doi.org/10.1038/s41380-021-01397-3

URL: https://www.nature.com/articles/s41380-021-01397-3

My urologist sent me home with packets about these treatments, she feels they may help me. I’m looking for additional info/studies. And if you have one, what were your symptoms before you got it, and how did it help you?

Also, I should say I’ve never been diagnosed with IC, only OAB. But I suspect I have more than OAB, given I have flares and pain/discomfort in my bladder. I’m currently treating my symptoms with 6-9 DH aloe vera and 2 pumpkin seed oil a day.

is there a role for surgery in IC / BPS patients ?

I've been listening to the neuromodulation generator from MyNoise for two days non-stop now. It masks my tinnitus 100% and even when I briefly go out I don't hear it anymore for a few minutes. I even left it on at night and slept pretty well (in contrast to before).

My question is - am I hindering habituation by doing this? I feel like it makes sense that my brain will never learn to tune out the ringing if the ringing doesn't exist because of this sound loop. But I'm kind of nearing a point where I think I'll probably never want to turn it off again since it's much nicer than the constant ringing.

Hello there, I'm trying to figure out more about closed-loop neuromodulation/neurostimulation devices and how they relate to BCI science as a whole, and some of the tech involved there.

It seems based on my perceptions,

• closed-loop neurostimulation is a "new" tech / subfield even within the novel field of BCI
• most closed-loop neuromodulation research and work is highly medical-related or clinical, and not as accessible to someone from a pure CS background
• most BCI-related usage of ML techniques is focused around interpreting the signals from the spike trains, but as neuromodulation devices are mostly invasive, there are different technical challenges here

(If I'm wrong, please please correct me)

Which leads me to the question:

• what kind of technical challenges and questions exist within closed-loop neuromodulation devices that someone with an ML/AI computer science background could work on, in a non-clinical or non-medical setting?

It appears the ML-work I've found on BCI focuses mostly on EEG devices and signal interpretation, so I'm wondering what computational challenges come specifically with the "modulation" or "neurostimulation" aspects.

Thanks for your input.

Hello,

I was wondering about "neuromodulation videos" that can regularly be found on Youtube, such as this one for instance. My understanding is that they use the same "random tones" technique as the one used in professional therapies aiming at rewiring the brain by taking advantage of it's plasticity.

I was wondering what's the consensus here about those videos? I see 2 problems with them:

1. They're not "custom-made" for the patient, since they are released publicly on Youtube, so their efficiency is dubious at best;

2. With the recent studies according to which white noise and other "random" sounds can accelerate brain aging and rewire the brain in maladaptive ways (potentially triggering or worsening tinnitus), I fear these videos might also be harmful in that way.

Is there any strong opinions about these here?

Thanks

DOI: https://doi.org/10.1038/s41591-020-01173-w URL: https://www.nature.com/articles/s41591-020-01173-w

Thanks in advance!

URL: https://www.nature.com/articles/s41591-021-01480-w

DOI: https://doi.org/10.1038/s41591-021-01480-w