Microencapsulation Puns

I want to microencapsulate capsaicin to reduce the pungency and make it soluble in water. So I would encapsulate a dry cayenne pepper powder. Additionally, is it possible to make the powder to the size suitable for microencapsulation (2 mm at upper end) and what machinery would be used to achieve this?

Hi everyone,

I’m currently working on a dietary supplement that is meant to be absorbed via the oral mucosa. In an attempt to optimize buccal bioavailability I’ve learned a fair amount. The supplement should be hydrophilic enough to permeate saliva while also being lipophilic enough so that it can permeate the epithelium. My question is regarding microencapsulation which is often used to mask off-tastes. I’ve read that smaller nano-size particles are required to permeate into the epithelial cell layer. If this is the case, wouldn’t micro-encapsulated supplements be too big and need to shed their shell and breakdown to permeate. And if the active ingredient must leave the shell to permeate the cells, do micro-encapsulated bitter actives still mask these tastes? Do micro-encapsulated actives hinder bioavailability because they are too big?

Any help or additional information you could provide would be greatly appreciated. I come from a finance background so my knowledge in this area is somewhat limited.

THANK YOU!!!

I spend a lot of time helping people safely consume MDMA in the rave and burner scene. This means proper reagent drug testing and education about how to stay hydrated etc. I also do a good deal of counseling with people when they are on the drug. I do not sell it and I'm not advocating it's use.

I have an invention that relies on microcapsules that break from sheer stress and pressure to release marquis reagent for on site drug testing. I don't want to go into any more details, it's in the patenting process. The final product is roughly 10-50x cheaper than existing tech and can be kept in a wallet as it is a business card (vs bottles of dangerous chemicals on you at the club... I've seen it).

No company I have contacted can encapsulate marquis which is 100ml 95-98%concentrated sulfuric acid and 5ml 40% formaldehyde. Can someone with experience in this field point me somewhere that could make a small amount so I have a working prototype for my Kickstarter? The CEO of one company keeps insisting he can but he won't give me a price and we've been talking for 5 months!!!

I'm so tired of kids dying from taking things that are not the drugs they expect. My invention is a low cost (pennies) one time use device that would save lives.

If microencapsulation is out of the question I'd like to use a more bulky tech hopefully off the shelf like such: it would be a porous material that can stand up to this reagent, which initially has its pores sealed. The user would remove a plastic covering on the porous material to release the liquid reagent on the other side of the porous material (or in the pores) through the pores. The entire device would be a thin HDPE card with a well in it containing the reagent, this covered by a porous material like laser drilled hdpe with another material that could stick to the porous material sealing it but not reacting with the reagent... teflon rape of a sort? Gah help! Again I've designed many methods for this to work but can't find an off the shelf products. A two part one with small holes then the next layer with no holes would do the trick. But what would stick and not react?!

The other version I dreamed up uses glass micro needles full of reagent that both work as an abrasive surface as well as holding and releasing the reagent. This is one version of my scratch and test technology I'm patenting...

I'm new to Reddit so I'm sorry if this is the wrong place for this etc. I just really need a working model that is presen

Hello r/soylent!

One of my major fears has been dealing with taste, esp. w.r.t. to thing like b-vitamin powders. Does anyone here have experience with microencapsulation?