How is oral dosing stronger than insufflation in 2-Fluorodeschloroketamine?
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πŸ‘€︎ u/Jossit
πŸ“…︎ Dec 22 2021
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Insufflation?

So i’m not a fan of the whole 2hr come up period, how is snorting this stuff? i’ve heard 2c-b is terrible when snorting but what about 2c-b-fly? Also does it hit faster?

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πŸ‘€︎ u/reptivity
πŸ“…︎ Jan 03 2022
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How long does insufflation of extract last and does it benefit to redose an hour or two later?
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πŸ‘€︎ u/CodyRebel
πŸ“…︎ Jan 05 2022
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Insufflation?

Is 5meodmt safe to insufflate. What should you consider before going this route?

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πŸ‘€︎ u/Kidsintheclub
πŸ“…︎ Dec 13 2021
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DPT Insufflation dosage

Today I did DPT today for the first time. I snorted 25mgs waited 20 minutes to see how I feel then snorted another 25mgs. I had a sensation that the room was breathing and there was a added depth to things that didn't exist before. I found I had a good time but want to do a higher dose my next go to have a fuller experience. I've read dosing can be difficult to figure out with this one and its easy to have a scare on, so I figure I'd ask and you fine folk for some general advice for my next trip.

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πŸ‘€︎ u/WithMyRichard
πŸ“…︎ Dec 14 2021
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Psilocybin extraction for insufflation

A while ago I met this kid who had extracted psilocybin into a form that can be taken up the nose. May have been something else but i dont think they had any reason to lie to me about it. Easy to take unlike 2cb. Was wondering if anyone knew how to do this. It was a very interesting experience.

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πŸ“…︎ Dec 22 2021
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Insufflation of 4F-MPH question

If I snort 4F will it last as long as if I ate it? If not how long does is last based on your experience? Is it stronger than eating it? I'd assume it'll hit pretty damn fast but will it be stronger?

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πŸ‘€︎ u/coffeebeans1912
πŸ“…︎ Dec 18 2021
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How does everyone feel about adderall + insufflation?

Hey there!

I was just recently diagnosed with ADHD, and as such I was prescribed with medication, and after going through a bunch of different meds / dosages I found that 30mg vyvanse works best for my symptoms. Regardless, I was prescribed with adderall xr 30mg at one point and have a bunch of them leftover as they didn't do anything and I never took them, so I decided to snort them. Lots of people say not to snort them as there's no benefit to them, which is somewhat true, but for me i wanted something that was just a quick little buzz for a little bit at night then I could get to bed. I crushed up 3 pills' worth of the little beads since it was XR and I wanted to get to the actual adderall, and then snorted them. For reference, that's about 90mg worth of adderall minus the stuff I lost while crushing it (minimal). I have a really high tolerance naturally to a lot of different things, so that was the perfect recreational dose for me, but it's different for everyone. I felt great! I was super focused, energized, and even got a euphoric boost. It doesn't compare to anything else I've done, but in its own way it's really nice and I'd highly recommend.

All of that is to say, I haven't done a lot (really just weeds + shrooms and I tried hydrocodone once but it did nothing), and I wanted to hear your opinions on it. It's not something I plan to do regularly, but was worth the effort that went into crushing them and I certainly enjoyed myself.

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πŸ‘€︎ u/cumfest_throwaway
πŸ“…︎ Nov 18 2021
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I see your Carolina reaper bong rip and raise you some incendiary insufflation v.redd.it/zofm0q8omzi61
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πŸ‘€︎ u/Sovereign_State
πŸ“…︎ Feb 22 2021
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How long until you start seeing the affects of insufflation?

I use pills and basically snort shit on and off all the time. I am prescribed 30mg adderall and i snort it every day and i was wondering how long until my nasal walls start weakening? Has anyone ever suffered any serious nasal or sinus damage from addiction?

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πŸ‘€︎ u/mellowjellie
πŸ“…︎ Aug 26 2021
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Rectal Ozone Insufflation

Today I stumbled upon something called Rectal Ozone Insufflation Has someone heard of it or even tried for SIBO? Any information is welcome.

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πŸ‘€︎ u/uozo
πŸ“…︎ Sep 27 2021
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Combining ketamine and EGCG for insufflation?

With preliminary studies showing protective effects of simultaneous EGCG and ketamine treatment (https://doi.org/10.1016/j.urols.2015.07.010), would it be possible to combine EGCG powder with recreational and therapeutic ketamine to reduce adverse effects on the bladder?

Motivation for combined ketamine-EGCG:

  • Effortless protection of patients and/or recreational users, no individual compliant required to mitigate the risk of ketamine-induced cystitis, combination ensures simultaneous administration

Questions:

  • What is the intranasal bioavailability of EGCG? Is there anything apparent about the structure that might be an issue for this ROA?
  • Would the amount of EGCG be too large (i.e. ratio of ketamine/EGCG too large, meaning not enough ketamine for desired effect)?
  • For therapeutic use, could EGCG be incorporated into a ketamine nasal spray and/or IV infusion (I assume the latter would be fairly straightforward)?

Would be interesting to see what people think about this. Using studies like this to better formulate drugs to include protective compounds could be an interesting avenue for harm reduction without the need for personal compliance, and could aid in changing the reputation of drugs as being completely unsafe and users/dealers worthy of prosecution.

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πŸ“…︎ Oct 03 2021
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Is kratom biovailable through insufflation?

I spent an hour snorting 8+ grams. It was hell. I decided it doesn't work. I would just take it orally but I can't do that for a week due to an intense throat-fucking session two days ago.

So here's my question, if I snort a powerful (300X) kratom extract will that get me high?

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πŸ‘€︎ u/Big_Ass_Boof
πŸ“…︎ Oct 05 2021
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Insufflation as a ROA for 3-FMA

I keep coming across contradictory reports about the effectiveness of this route of administration when it comes to 3-FMA. In the psychonautwiki it doesn't even appear at all. Knowdrugs on the other hand does mention it, but as a much less effective ROA (with little bioavailability, I guess), having to take much more than orally for the same effects.

Here on Reddit the information is even more contradictory: some people say this ROA has no bioavailability whatsoever (which is obviously false lol) while other say it's even more effective than taking it orally.

I've also read that it really depends on the batch of 3-FMA you have. I think that may be true. Mine is 100% pure 3-FMA hydrochloride, which some people say is the most snortable form of 3-FMA. And I snorted some the other day and found it a more effective ROA than taking it orally. Burns like hell though.

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πŸ‘€︎ u/mikelmon99
πŸ“…︎ Oct 16 2021
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The first vaccines were invented in 14th century China. Where powdered small pox scabs were blown up peoples noses. Nasal Insufflation killed 1 - 2% of recipients which was still preferable to smallpox. This method was brought to Europe in the late 17th century before being banned in the 1800's
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πŸ“…︎ Jun 11 2021
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Hydrocodone Birartrate / Homatropine Methylbromide. No APAP hydros, didn’t look much into the homatropine part but seemed legit, insufflation and boof-able πŸ˜†
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πŸ‘€︎ u/1UpTahpAhk
πŸ“…︎ Aug 15 2021
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TBI in Past Experimenting w Insufflation about 10mg a day

For the first time in years the chatter in my brain is going away, and the world feels more fluid. Can't wait to give this to my brother to try who also has TBI.

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πŸ‘€︎ u/kanooker
πŸ“…︎ Jul 30 2021
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A Kuripe (rapΓ© self applicator) is the best method of K insufflation that you've never tried reddit.com/gallery/pltppz
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πŸ‘€︎ u/nugiboy
πŸ“…︎ Sep 10 2021
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Wow. I see the point of insufflation.

I've recently started getting a bit of my morning caffeine by snorting small lines of powder. And caffeine that comes on in seconds is such a different experience than drinking a cup of tea and waiting 15 minutes to half an hour for the effects. I inhale, and by the time I can pull my attention away from the burning sensation in my sinuses there's a wave of wakefulness and life force sweeping through my head. It's amazing.

I'm never doing anything more addictive than caffeine by insufflation, because I love fast kinetics way more than is good for me.

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πŸ‘€︎ u/Devil_May_Kare
πŸ“…︎ Jul 19 2021
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No flash on this beautiful rock, all natural. How much does it weigh? Unfortunately my camera skills aren’t the best, there is a slight yellow tint and somewhat very pleasant light fruit notes upon insufflation. Very pleased, been doing this shit like coffee lol! All and all I just feel fucking A1.
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πŸ‘€︎ u/Lonely00001
πŸ“…︎ Jul 18 2021
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How do you crush up your crystals for insufflation?

I’ve been doing drugs for decades but I’ve always felt like there must be a cleaner way to bust up crystals to minimize the waste.

I’m curious what method do you use?

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πŸ‘€︎ u/readout99
πŸ“…︎ Jun 17 2021
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Insufflation/nasal spray waste?

I have used a nasal 3-mmc spray. Whenever I use it alot my nose will be producing alot of mucus that is also pretty watery. My question is if any on the prodcut gets wasted when I clear my nose i.e. how long does it take your nose to absorb it.
Maybe duration also differs compared to powder? I can image with a spray absorption is a bit faster.

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πŸ‘€︎ u/sugarbryat
πŸ“…︎ Oct 21 2021
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Insufflation

Yall ever Snort this shit? Robocough freebase

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πŸ‘€︎ u/ijustwanttowant
πŸ“…︎ Aug 14 2021
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Mxipr insufflation vs oral?

Had the chance to do mxipr but I was underwhelmed, honestly jsut didn’t have a good time. I’m somewhat new to dissociatives so I wasn’t sure what to expect but I teetered between barely feeling it and just feeling pessimistic and hazy. My dreams were very strange and scary afterwards as well.

My dose was 15mg plus another 15 an hour and a half later both orally? Is it worth redoing intranasaly? Should I expect more of the same or was I at a threshold?

If the trip is similar could I abort with a benzo and get some decent sleep?

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πŸ‘€︎ u/realmayonnaise4u
πŸ“…︎ Aug 16 2021
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The newest generation Arthrex arthroscopy tower, complete with NIR capabilities, fluid pump, and insufflation machine. We're gonna scope ALL THE THINGS!
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πŸ‘€︎ u/Tushness
πŸ“…︎ Jun 03 2021
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How to avoid getting nausea from K-drip at a higher dose? (insufflation)

Hey,

This has been an issue for years. When I do a smaller line at a low-moderate dose, I don't feel sick at all. But if I want a higher dose (not even k-hole level just more psychedelia..) I find that larger lines give me the drip and when I swallow it I get bad nausea, which hangs around a long time and really takes away from my trip.

I have taken gravol before with DXM preventatively and it seems effective, although I don't know how that would work with K - wouldn't want to get too sleepy and I think DXM tends to be more stimulating. It's a thought though. I've also heard of potentially taking several smaller lines over a period of time as opposed to one-two larger ones, that apparently reduces drip.

Any experience with these methods or suggestions? Thx.

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πŸ‘€︎ u/custard9
πŸ“…︎ Jun 13 2021
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I use a Small straw for Insufflation. You guys do that?

I have some nose hair hehe so in order to bypass the obstacle and also it goes much smoother. But my nose is very sensitive. I sneeze few times after i take it .

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πŸ‘€︎ u/internet_sherlock
πŸ“…︎ Aug 26 2021
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IM Ketamine high is sub par compared to insufflation.

I see IM recommended alot because of the efficiency of it but tbh Ive prolly IM’d about 10 times before going out and it just seems to be a very different experience then snorting it. With IM I get more of a hollow fucked up headspace. Where snorting appears more euphoric and trippier visuals. Anyone else notice a difference?

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πŸ‘€︎ u/Centrist_bot
πŸ“…︎ Aug 07 2021
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Light numbness after insufflation?

Hey all, my throat goes a tad bit numb when I snort ket, is there a chance it's cut with procaine or somn, or is that normal with ketamine?

I'm new if that's not clear haha

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πŸ‘€︎ u/DopeAccount2
πŸ“…︎ Jun 28 2021
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Insufflation vs smoking vs chewing vs drinking?

What are the differences in effect between the different ROA’s? I’ve only ever insufflated it and I loved the boost of energy and mood it gave me, so what are the other ways like?

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πŸ‘€︎ u/bruh_del_bruh
πŸ“…︎ Aug 26 2021
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2cb insufflation duration

What is the duration of 2cb when snorted? It's currently 23.27 here and I wanna try it before I have work tomorrow....

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πŸ‘€︎ u/Fluid-Mammoth
πŸ“…︎ Jul 11 2021
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Question about the insufflation (snorting) of Adderall IR

Hello everyone quick question I have read many places online that Adderall is not active when snorted, but I can't figure out why exactly that is. If anyone can tell what mechanics in the Adderall prevent this, is it something similar to how the new Oxycontin where it is render unless after it is crushed? Any scientific articles, anecdotes, or anything you know about this topic is greatly appreciated!

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πŸ‘€︎ u/TheDailyDouble-
πŸ“…︎ May 22 2021
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Best method for insufflation

Is there a best method to insufflate drugs by means of straw lenght, depth, how hard I sniff, where I put the straw in my nose, how much at once, preventing drip etc. Also is there a difference if the drug is powdery or more clumpy?

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πŸ‘€︎ u/Gifleo93
πŸ“…︎ Jun 03 2021
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insufflation of R | P 30 pill (oxycodone hydrochloride 30mg)

okay so, i have acquired a legit R | P 30 labeled pill (oxycodone hydrochloride 30mg), and was wondering if it is okay to snort?

usually i obtain the little blue round ones with the M in the square on the back, and they’re smaller so less dust to inhale…but this one is significantly bigger but i’d love to be able to snort it, just wondering if it’s okay

(i can confirm it’s a legit pill from the pharm & contains no acetaminophen)

any help would be greatly appreciated!

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πŸ‘€︎ u/philv94
πŸ“…︎ Jun 10 2021
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How gnarly is 2cb fly insufflation

I've heard it feels a bit like let with this roa

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πŸ‘€︎ u/yojibara
πŸ“…︎ Mar 22 2021
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The first vaccines were invented in 14th century China. Where powdered small pox scabs were blown up peoples noses. Nasal Insufflation killed 1 - 2% of recipients which was still preferable to smallpox. This method was brought to Europe in the late 17th century before being banned in the 1800's
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πŸ“…︎ Jun 11 2021
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*laughs in insufflation*
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πŸ‘€︎ u/The-LSD-Sheet-Guy
πŸ“…︎ May 27 2020
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Can anyone dumb down this sentence about insufflation for me?

I saw this on a page discussing insufflating noopept. It seems to be suggesting that intranasal administration allows certain chemicals to pass the BBB easier. But I thought that had to do with the compound's chemical properties, not route of administration.

"The nose enables certain drugs and other molecules to bypass the blood brain barrier via diffusion through the olfactory epithelium and the perineural sheath or via retrograde axonal transport along olfactory and trigeminal nerves."

So can anyone tell me what the above quote is really saying? And is it true?

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πŸ“…︎ Oct 15 2020
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DXM HBR:a guinea pig test on insufflation
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πŸ‘€︎ u/boldremington18
πŸ“…︎ Feb 25 2021
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Insufflation

What are all the benzos that are worth taking by snoring? I’ve hard you can with Triazolam, but that’s about the only one I’ve heard. I’m wondering if any of the others work. Thanks for the help.

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πŸ‘€︎ u/the-big-hoss-20
πŸ“…︎ Mar 07 2021
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