Hi everyone! I'm 25 years old and I was diagnosed with ET about 2.5 years ago (JAK2 positive). So far I've been taking aspirin 1-2 times a day, and my platelets count has been rising steadily from 600 when I was diagnosed to 1900 today. After my recent blood tests my hematologist suggested that I will start taking Hydroxyurea to lower the count.
I am a bit worried about the side effects of this drug, and the restrictions that come with it. My doctor also told me that this is probably going to be a permenant thing now, although I've read in a few posts here about people who only took it for a relatively short period of time.
If you take hydroxyurea or took it before, I'd be happy if you could share your experience with it, particularly the side effects and how it affected your daily life if at all.
Another slightly unrelated question, I haven't had a lot of symptoms so far but I do sometimes have moments of a mild (but annoying) dizziness, went to a few doctors and couldn't find a reason for it, and my hematologist says that it might be because of the ET. Is this a common symptom? And if so will lowering my platelets count help with it?
TL;DR Had ET for 2.5 years and my platelets count just got to 1900, doctor suggested Hydroxyurea and I'm worried about the side effect. If you have experience with it I'd be happy if you could share it.
Thanks in advance!
Edit: thank you everyone for your responses and your support! I feel much more calm and reassured now, and I learned about some tips and options I could discuss with my doctor. I was worried that this community might not be very active, and I'm glad to see that's not the case. Thank you for being so supportive and helpful!
I've been on this Chemotherapy for 7 days now for my condition. What pitfalls do I have to look out for? I have 30 days X2 500MG capsules as my initial prescription.
After waiting for many years and a lot of observation, my doctor finally put me on Hydroxyurea after I came out of the hospital at the beginning of this year. Now, this time, my crisis was different in many aspects, and I think it was quite obvious to my doctor that it affected me more mentally than it did physically. All my cousins also noticed how very weak I had become (much more than usual), despite there not being any pain as such.
After observing myself for the last three months, here are some major changes I have noticed -
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I simply CANNOT remember things...what people say, or where I put something, or what I had to do next. This hasn't happened to me in life so far so it's a bit unnerving/disconcerting. My mind is mostly on an overdrive of ideas, but the thoughts seem to vanish faster than they appear.
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I type the wrong things, make really silly spelling errors, and I can't afford to do that since I make a living as a writer.
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For the last few months, a few days/weeks before menstruation, I lose sleep. I barely get 2-3 hours of sleep at night. This is again, a new issue.
I checked with my doctor and he's told me Hydroxyurea has absolutely no side effects (which is why so much research was done before he added it to my list of daily medicines). But there has been no other change in my lifestyle. Has anybody else experienced any short term memory loss, or any other mental health issue?
My mom has recently been diagnosed with PV (the JAK2 kind) and her doctor recommended hydroxyurea for medication treatment. She has been Googling everything and some of the symptoms say that you can be out in the sun or you can’t get vaccines. Naturally she has been incredibly nervous and anxious about taking it due to the side effects.
I’m just trying to reach out to people who may have experience with this disease and medication to help ease her mind some.
As the title states, I could use some opinions from the community concerning Hydroxyurea. Specifically what benefits have you noticed and any issues with the side effects. My hematologist just prescribed this medication and I'm a bit nervous. This is my first major prescription to help treat this.
I've googled, but can't find the reason.
Here's the warning: Hydroxyurea capsules and tablets should be handled with care. People who are not taking hydroxyurea should avoid touching it. To decrease your chance of touching the medicine:
Wear disposable gloves when handling the bottle or medicine.Wash your hands with soap and water before and after contact with the bottle or medicine.Do not open the capsules or break the tablets. Avoid exposure to crushed, broken, or opened capsules or tablets.If you touch an opened capsule or crushed tablet, wash your skin right away with soap and water.If powder from the capsule or crushed tablets get into your eyes, rinse them with water or an isotonic eyewash for at least 15 minutes.If powder from the capsule or broken tablet is spilled, wipe it up right away with a damp disposable towel. Place the towel and the empty capsule in a closed container, such as a plastic bag.The area where the powder spilled should be cleaned 3 times using a detergent solution followed by clean water.
Doesn't S phase = DNA synthesis/duplication? ...then, why would hydroxyurea which acts on the S-phase cause non-megaloblastic macrocytosis?
- What's the mechanism?
- Is this an important AE to know for hydroxyurea?
https://preview.redd.it/cywl5419xvl41.png?width=450&format=png&auto=webp&s=0e46f0f2f485b86376564754c3a4af80f2b18385
I take hydroxyurea for a myeloproliferative neoplasm. The drug comes with all these dire warnings about wearing gloves when handling the pills, washing hands afterwards, etc...but doesn't tell the consequences. I've googled and asked my MPN Facebook group and can't find an answer.
Hi im 23 years old and i have been taking hydroxyurea pills for the past 5 months due to sickle cell anemia.
I know one of the side effects of hydroxyurea is a reduction in white blood cells and since there is an outbreak of Covid-19 where i live i'm scared my body cannot defend itself if i get sick with the virus. Should i continue taking hydroxyurea pills?
SC-D here.
I'm fairly certain that HU made going through puberty way more problematic. Is that just me?
And I'm about to go to college within a year so I'm trying to prepare for it. My case isn't that severe thank god for it. Any tips? I'll be living away from family but fairly close to my relatives if that's what you are concerned about.
I'm trying to build up my immunity and non-existent fitness rn to cope up with the college life. I've not learnt to run and my legs are weak but i can walk certain kilometres when I need to, cope with school life when I need to with certain breaks between. It's just that my parents protected me too much than they should have, I've got brains but not a body that can sustain it.
16 years in and I'm trying to learn to live now. Any advice, comment or insights into your own journey are welcome!
So according to Uworld, hydroxyurea is listed as inhibiting both pyrimidine and purine synthesis, but when you look at the diagram it only inhibits pyrimidine synthesis (https://imgur.com/a/eiZZuwi). Can anybody clear up this kerfuffle? Thank you so much!
Do your worst!
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂
It really does, I swear!
I'm surprised it hasn't decade.
They’re on standbi
Buenosdillas
Pilot on me!!
I was just diagnosed with Chronic Neutrophilic Leukemia (CNL), which I am told is rare. Is there anyone else out there with it?
Next, my spleen is extremely enlarged and causes distress. Is there anyone out there that can tell me what they do for that to help relieve symptoms?
Currently my blood count isn't all that bad and the only reason they want me to start Hydrea is to relieve the spleen symptoms. But I'm told that it could negatively affect my blood count. Therefore, I am hesitant. I would rather endure the spleen symptoms than to upset my current blood counts.
Is there anyone currently taking Hydrea?
Thank you in advance. I'm really quite upset about all this as I am told that a prognosis for CNL isn't that great.
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
When I got home, they were still there.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
I won't be doing that today!
