Generic Medication Puns

Hi everyone, I’m a 26f and recently diagnosed. I’m on my 4th day of taking generic adderll XR. I know it’s not the name brand so I’m not sure if there is a difference in the effects. I feel really calm and focused, but very very sleepy. Is this a normal side effect? Has anyone else had this experience? I feel like I would prefer the name brand because it seems more reliable? But maybe I’m making assumptions. Im on 10mg and need a nap. I slept well through the night and everything. Thank you! I appreciate any feedback or if you could share your experience taking the generic version of adderall.

I everyone New to taking medication for my ADHD (26f) . I’m in day 4 of taking generic Adderall. My insurance does not cover the brand name. I’m not sure if there is a major difference in the effects. I currently feel very calm with no anxiety, and focused! I can hear conversations so much better. The benefits are great because Iv taking anti anxiety medication in the past and in never worked. However, I feel very very sleepy. I’m sleeping well at night so far and I wake up refreshed. But 30 mins after I take my medicine I feel like I need a nap. Is this normal? Has anyone experienced this before? Is generic as effective as the brand name? Thanks for any feedback!

I (29M) was just prescribed adderoll by my psychiatrist a few month ago and we are still working out the dosages. It has been working well for me at work, and I finally feel like the attention issues I’ve had and been ignoring since high school is finally behind me. However I noticed now where on the actual pill bottle does it say the word adderoll. This makes me a little nervous . If I am being completely honest I was a little apprehensive to start taking it in the first place. After the first month at 5mgs I felt I should continue as I was happy with the results. I’m reading about things like “binders” and other things they add to generic brands. How should I go about discussing this with my doctor? I am seeing her again on Thursday and would like to voice my concerns. Is this even an issue or something I’ve built up in my head?

Thanks everyone!

Objective: I want to verify the purity of generics (in powder form) for a large group of people who cannot afford branded versions (no medical insurance). I'm starting with rapamycin. They're taking these generics already anyway, therefore what I'll be doing can only help. I won't charge them; I just love chemistry.

I searched on Google for this: "certificate of analysis" "rapamycin" filetype:pdf

I found a lot of these certificates and got an idea about how professional labs go about testing this macrolide. I want to start with the easiest methods that I could later repurpose for analyzing other compounds. I don't want to use more than a few milligrams of rapamycin in total, for all tests.

First off, I guess I need access to a 100% pure sample in order to compare the physical appearance, the smell, and the taste (it's not toxic).

Then, check the melting point (it should be 183-185 °C). What melting-point apparatus would you recommend?

Elemental analysis. What CHNS (O) Analyzer do you recommend? Cost is not an issue; I want good technology.

I'm also considering determining the wavelength of maximum absorbance (λ max). How would that work? I'd have to buy a UV-visible double beam spectrophotometer that has a scanning facility, then prepare a solution of 1mg rapamycin in 1mL of methanol and put it through?

A list of other things that I've seen tested for rapamycin (please tell me what you'd to do if you were in my situation):

• testing solubility in various solutions; I found this kind of info: DMSO (25 mg/ml) Ethanol (9 mg/ml), or Methanol (1 mg/ml)
• water content
• loss on drying
• residue on ignition
• heavy metals content
• these three might be too bothersome or expensive: HPLC, TLC, ^(1)H-NMR

Unrelated, if anyone is in Spain and would like to help after I buy the equipment, hit me up with a private message; I will pay your traveling/food/Airbnb expenses.

Fellow people with ADHD... UNITE! At this point, I'm ready for a class action lawsuit because I am so tired of the variation between generic manufacturers of Adderall. How is this not criminal?

I'm low income and struggling but still willing to pay for brand name (without GoodRX because no surprise here, pharmacists have been refusing discounts on controlled substances).

I was writing this post to vent, but I'm actually very interested in dealing Big Pharma a heavy blow. There's power in numbers, folks. If we can collectively use our hyperfocus and impulsivity to take these MFers down, it would be a net positive for society.

Edit: Variation /in efficacy/. (Sorry, this generic has wrecked my sleep.)

Hello, I take Vyvanse for my ADHD and it is critical for my ability to function. Unfortunately, every time I have changed insurance it has been a nightmare for me to acquire my medication because the insurance companies have various policies to deter doctors from prescribing non-generic medications (no generic of Vyvanse is available, other ADHD medications are not comparable and give me terrible side effects).

I am losing my insurance at the end of the month because I was flagged as eligible for Medicaid (I am a graduate student, I am making the same, low amount of money as last year, no one has been able to explain this change to me). My application is still pending. They say it takes 45 day so hypothetically I should receive notice about my insurance on January 28, fingers crossed. Given the number of pills I have currently and the refill I can pick up at the end of the month, I will have enough medication to get me through February 26.

Do you have any advice for getting my insurance (Horizon BCBS) to cover more than 30 pills for my refill this month? Or for getting around insurance policies dissuading doctors from prescribing non-generic medication? I always eventually get my medication, but it has taken anywhere between weeks and months to approve. In that period of time, my work, life, and ability to cope with comorbid mental conditions hit an extreme downward spiral. I don't want to do that again. Paying out of pocket for this medication is not possible for me, it is incredibly expensive. Any advice you have is very very appreciated, thank you.

I've long been a skeptic on the topic of medication effectiveness amongst different generic manufacturers, to include generic versus brand name. Finally, after reading several hundred posts on many different forums, it was my turn to test the theory. My pharmacy (Wegmans) stopped carrying Mallinckrodt dexedrine (generic) and only carries Aurobindo dexedrine (generic). Based on everything I read about Aurobindo, I had my doctor write a prescription specifically for Zenzedi (brand name) and to NOT substitute with generic formula if brand name was unavailable. After taking Zenzedi for a week, I've learned Zenzedi's (brand name) therapeutic effects differ from Mallinckrodt dexedrine (generic) even though both claim to be "dextroamphetamine"

For me, Zenzedi's effects are very "cerebral" and is practically free of that "physical" stimulation feeling. Mallinckrodt Dexedrine still has a small amount of that "physical" stimulation feeling but it isn't overbearing/feels smooth. And recounting from previous medication history, Adderall (75% dextroamphetamine/25% levoamphetamine) felt very stimulating and produced the most side effects (increased heart rate/blood pressure, loss of appetite/nausea, headaches, feeling dull/zombie-like).

My theory:
Hypothetically, if generic medications are supposed to mirror the therapeutic effects of brand name medications and brand name formulas are the most potent/pure form of the medication (Zenzedi and dextroamphetamine in this instance), then this leads me to believe generic manufacturers, like Mallinckrodt or Aurobindo, are not creating a "one-to-one" copy of the brand name medication.

Now, based on experience and what I've read about dextroamphetamine/levoamphetamine, Zenzedi seems like it may actually be pure dextroamphetamine, whereas the generics, like Mallinckrodt and Aurobindo, may still contain various amounts of levoamphetamine (assuming levoamphetamine plays a large role in the physical side effects felt from amphetamine medications)

My question to all of you wonderful people:
Has anyone else noticed differences in medication effectiveness when switching between different generic manufacturers and/or switching from generic to brand name/brand name to generic? And are there any experts out there that understand drug manufacturing and can better explain generic vs brand name, along with policies or guidelines manufacturers must follow when producing a generic formula of a drug?

American here who’s sick and tired of their country’s idiotic healthcare system. Seems like doctors are always prescribing new medications with no generics available and requires jumping through hoops to get a better price (like good rx, speciality pharmacies etc)

My question is; I know a lot of medications are covered by the NHS, but does this include brand new meds with no generic option? Does the NHS require you to try other medications first?

Edit: I feel I should make it clear that I myself do not want to be prescribed these brand new expensive drugs, rather it’s the doctor I go to that always prescribes new shit that’s way too expensive.

Unfortunately, I don’t think there is one available generic from what I can tell online, but I figured if anyone would know it’s someone on this forum. Generic medication is $10/month on my insurance, name brand is $60/month…

I have severe leg pain from an accident years ago and subsequent medical injury during the repair - so I take an opioid daily for that, which makes my life almost livable. Problem is I have gastroparesis too, and the constipating effect of my pain medication is aggravating that and causing some pretty severe GI pain too.

Anyway, my doctor prescribed Symproic, which is definitely helping reduce the GI pain. It makes things a little too loose which is inconvenient, but that seems to be an acceptable trade off to have less pain in my intestines without giving up my opioid for my leg pain.

Problem is I doubt I can really afford it as a monthly med once I run out of the trial pack since there is no generic. It’s the best option I’ve tried so far though so that sucks. $60 a month even with insurance is no small bill! I hate the insurance extortionists and the pharma-cartel so much. Preying on sick people for a unreasonable profit, it’s disgusting. But that’s getting off on a tangent…

So anyway, I understand there is no generic for Symproic, but apparently there is not even another peripheral selective opioid antagonist available generic at all! The only generic indicated for OIC is Lubiprostone which is a chloride secretion inducer not an opioid antagonist and I doubt it will work as well for me and will probably upset my GI pain and nausea even more, just like OTC laxatives do.

What I need is a peripheral selective opioid antagonist, but unless someone knows an obscure generic one, looks like I’m out of luck or will have to shell out the big bucks for the name brands $$$$

Sometimes the pharmacist will say, “We’re out of brand name medication, is generic okay?” I always say yes. Is there any reason someone would say no? It’s the exact same thing.

As the title says my doctor is a god and I'm so lucky to have him. Here are some tips he's gave me that have been extremely helpful in my treatment.

• Medication holidays: Don't bother. He's been on Adderall for over 2 decades now and it still works at the right dose. He also says that taking med holidays can even set you up for anxiety and depression because of the withdrawal and recovery
• Tolerance building: There is a limit to how much tolerance you can build. It's OK to increase your dose if you need to. Eventually you will no longer need to increase it
• Waking up in the morning: If you struggle to wake up in the morning like many of us taking stimulant meds take your morning dose one hour before you actually have to wake up. Then, just go back to sleep for another hour (have 2 alarms).
  • I can personally confirm this makes mornings much easier. I can also confirm that I am perfectly capable of sleeping another 3 hours after taking my meds if I don't set an alarm lol
• Starting dosage: Your weight, height, and gender have exactly nothing to do with starting dosage. It's all about your genetics. He has very heavy patients who take almost none and tiny patients who take a lot
• Starting a new stimulant med: The side effects will be the worst the first two weeks. If it's helping your ADHD and the side effects aren't completely unbearable tough it out for at least two weeks before reducing dose or trying a different med
• You can be very smart and still have the condition: My doctor is very smart and successful despite also having high functioning autism in addition to ADHD. Many psychologists will assume you have anxiety, BPD, etc. Ask your psych to let you try meds for a limited time (at least 3 months) then reevaluate. Smart people with ADHD are very difficult to diagnose but treatment can be life changing despite already performing acceptably in work and school
• Therapy is the single best thing you can spend your money on if you need it: I have personally never needed therapy but he is very open about his own mental health and mentioned it in passing

Disclaimer: I am not a doctor. This is second hand advice. My doctor is a primary care physician not a psych. These tips may not be true for all people with ADHD but they should be true for most. If any of these things don't apply to you your condition is still valid. Please see a mental health professional for further guidance

TLDR: Medication holidays are not

I vomited yesterday and I thought maybe i just ate something bad but my body is still having random pains and fatigue, blood circulation issues, etc.

Just sick in general. I think I just might be allergic to one of the non-active ingredients in the generic version

I usually always get brand focalin (or I think it's brand at least I'm not too sure) although i never asked for it.

I googled the differences and holy shit, the generic has way more non-active ingredients which I don't understand why it'd be necessary anyways

All this is after a WEEK of waiting for CVS to get it stocked up even tho I called them a week in advance

I fucking hate this world jfc

And to make matters worse I have to go on a trip tomorrow for a couple of days 😫

I (29F, USA) started trialling medications this year, and went through focalin, ritalin and adderall all with not super great effect, although adderall was the best, I liked the mood effects. These were all the generic versions. I started Vyvanse and that was the only one that has helped me focus at all, and is the only name brand one I've tried because there's no generic.

I read in Russell Barkley's book that sometimes the generic versions aren't made as well as the name brand, and so was wondering what people's experiences with the brand name medications are like (I'm asking my psychiatrist tomorrow, but just wanted to get people's opinions.) I'm wanting to try Adderall again because I like the immediate release. Thanks in advance!

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So…I feel like I’m going off the rails today and yesterday, and I think maybe I’ve figured out why, but I have no idea what to do about it.

I get my Adderall XR 20mg delivered through Express Scripts because it’s my insurance company’s preferred vender and it costs me $63 for a 30 day supply rather than $85ish from the cheapest pharmacy around me. I’ve always gotten name brand because the insurance wouldn’t cover generic. I met with my doctor a couple of weeks ago and she moved my dosage up to 25mg.

The rx was delivered from Express Scripts and I started on it 2 days ago…and it’s not name brand. They charged me the same cost for name brand, but the insurance company paid nothing for it. I literally feel like I’m insane. I’m ridiculously hungry. I’m overly emotional. I can’t complete even a single task, and I have 88 more days of this shit.

Anyone else experience this when switching from name brand to generic? Am I just really losing my mind and it’s not the medication change?

I've been using Aerius which is the only one that works for me. I noticed they're selling it at Dollarama under it's generic name Desloratadine. Anyone know if it's just as effective?

I got prescribed medication for adhd back in like...2013-2014. the family doctor basically told me it was instant release Adderall. The label of course didn't say that, but I assumed that duh, it was a generic. Now from 2014 to 2019 I traveled cross country, had two new doctors, and still got refills. I was taking what I thought was Adderall. I brought the prescriptions and the doctor visit summaries to each new doc.

Then, one day, after I moved and had everything sent to my new local chain pharmacy the pill changed shape. It was weird. Same color, but still. The name on the label wasn't the same. I asked the pharmacist why it was different and they said it was a different generic and it was all the same.

This new pill is less effective for me, I dislike it. I recently asked to up the dose and the new dose is more garbage (second refill last night).

But lo and behold, the pharmacy tech at the drive through LISTENED to me when I said I needed a different generic and that the brand had changed somehow and it was worse. And I wanted to know if they could replace it or refill it or what to tell my doctor to get something else that wasn't garbage. FINALLY SOMEONE AT THE PHARMACY HELPED ME!!!

God bless this pharmacy tech who LISTENED and RESEARCHED and specifically told me I had taken another one before, who even gave me the NAME of the generic manufacturer I'd used, and who told me if I had it requested they could fill that order specifically.

It took a year but someone finally explained to me why my medication was different. I'm so happy I could cry.

I’ve noticed some unexpected positive effects of starting generic Dexedrine aka dextroamphetamine.

First is the calming effect it has on me. It is so clear now that my anxiety stemmed from my ADD. I can control my thoughts better and stop and redirect my thoughts. I honestly didn’t realize how absolutely chaotic my brain constantly was until it wasn’t. I guess this is what it’s supposed to do but I was expected to feel all zoomed out thinking of it being an upper.

So I think this second effect may be a result of the first effect. It has actually lowered my heart rate and blood pressure a bit. My normal resting heart rate is anywhere from 85-100bpm. Can EASILY spike to 120 when I drink coffee or get anxious. Which is a lot. I would get heart palpitations often and feel huge thumps in my chest, like my heart skipping a beat.

My heart palpitations are nearly non existent. My blood pressure has been running 110-120/80-85. Usually it’s a bit higher 130/90-95 and that’s with a small amt of medication I take for high blood pressure. My pulse has been in the 75-85 range. I honestly expected my heart palpitations to get so much worse but the fact that I can’t feel my heart beating out of my chest is insane and relieving. Makes me wonder the physical toll this neurotransmitter deficiency can have on your body and how related these things are.

I also have better sexual response. I expected to feel desensitized and lose interest in sex as I’ve read thats a side effect of the medication being a vasoconstrictor. Luckily it’s been the opposite for me. Arousal and sex have both felt better and been easier, but I’m also not fiending for sex or getting upset if my partner doesn’t want to have sex like I was before medication.

Another random thing is my skin. My skin feels smoother almost like my pores are smaller. Perhaps this has something to do with the vasoconstriction.

I feel much less of a brat, everything doesn’t feel like a huge ask or the end of the world. I can just do stuff. The insane amount of chatter in my mind is quieter.

Some of the negative side effects are lack of appetite which I think also contributes to the comedown that can be a little gnarly at times. Working on hammering out my eating habits while medicated. I was on bupropion 300mg but I stopped taking it as it was giving me an absolutely horrid headache in conjunction to the dex. Been off of it for 5 days with an occasional brain zap and that’s all.

I’ve only been on the medication f

For instance ibuprofen is a common drug but the name ridiculous and means nothing to the layperson. Motrin is a brand name for ibuprofen, but is just as meaningless and ridiculous sounding. How do brands come up with their names and why not call it something like Feelbetteratrin?

Hiya,

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Which Pharmaceutical companies from list A: Accord, Aspire, Cipla, Kosei, Medreich, Milpharm, Mylan, Strides Pharma, Sovereign, Sun, Teva?

Which Pharmaceutical companies from list B: Accord, Milllpharm, Teva?

May please kindly consider your recommendation based on the most effective of the product and minimum side effects of the product, please?

Tnx and best of luck