Can someone explain why this is allowed? This confuses me greatly, as DCM is a polar solvent yet toluene is non-polar. What polarity does LSA even have?? Could someone explain this from a chemical point of view? Thanks in advance!
I am purchasing my chemicals for a Methcathinone synthesis but I am having trouble finding Toluene. I do have access to Mineral Turpentine, Benzene, Thinners and sometimes Xylene. Which could I use?
I'm a layman just doing research in cannabinoid isomerization for fun and future reference if you have any important info for me in my pursuits.
I've been buying and using Weldwood Original Contact Cement, which has toluene in it. Once I open it, I put it in a squeeze bottle and store that in a Ziplock to try to prevent evaporation. But even doing this, I only get about 6 months of use out of it before it gets too thick and stringy to use. I've even tried thinning it with various solvents including Xylene, but that only works for a short time.
Just wondering if the toluene-free formulas work just as well, as long as you allow for the longer drying and set time? I'd suspect that without solvents, evaporation would slow down and the contact cement would be usable for a longer time after opening ... is that correct?
Does anyone have any tips on how best to store either type of contact cement so you can get at least a year's use out of it after opening?
Introduction:
The first thing people complain about with regards to the citric acid method is that the maximum delta-9-THC concentration achievable is only about 50%, with the other 50% being d8-THC, unreacted CBD, and unknown concentrations of intermediate cannabinoid isomers. Furthermore monitoring the progress of the isomerization is not possible with the cheap and simple beam test, unless you are trying to achieve 100% d8 content. With a more specific catalyst, we can achieve 90%+ d9-THC which can be easily distilled into 99%+ THC distillate. This procedure is not for beginners. We will be dealing with volatile and flammable organic solvents, (things you're not going to be buying from Bezos, you'll need to know how to source actual reagents for this one) and $500-1000 investment to get started (assuming you had no equipment or reagents at all). The procedure is relatively simple, but requires a fair amount of equipment to accomplish. let's begin.
Reagents:
p-toluenesulfonic acid monohydrate
toluene (dry. if you're not sure if it's dry, dry it. We're not doing grignards here but p-tsa is much more soluble in water than toluene and we need it in the organic phase to isomerize the CBD)
CBD isolate or distillate
sodium bicarbonate
If performing optional chromatography:
pentane
ether
alumina
Equipment:
small boiling flasks
hot plate/ heating mantle appropriate for your boiling flasks
200mm leibig condenser
1/4" ID tubing
aquarium pump
short-path distillation head w/ ground glass thermometer
small receiving flask
vacuum source capable of achieving and maintaining 20 torr/97% absolute vacuum
separatory funnel
milligram-accurate scale
pipettes
orange litmus paper
Procedure:
Isomerization:
To 100ml dry toluene 200mg p-tsa monohydrate is added. To the solvent we add 3gr CBD and reflux for 1-2 hours, until Beam test is negative for CBD (no color). Cool to room temp and move on to workup. Even though refluxing typically produces little-to-no smell, I would still recommend performing the reflux in a fume hood or in a well ventilated area.
Workup:
Neutralization and washes
Neutralize the reaction mixture with 100ml 5% sodium bicarb solution. Separate, keeping the organic phase. Wash the reaction mixture with 100ml dH2O. Separate as before. If the toluene appears to have taken on water, dry with CaCl2 or 3A molecular sie
... keep reading on reddit β‘Hi everyone
My second post here.
Story so far: I inherited a Shimazdu GC-MS 2010 system at my work place. System works well. But, am totally new to chromatography as a whole. My objective is to quantify polyaromatic hydrocarbons extracted from soil samples using toluene.
Since these are carcinogenic and costly to procure, I decided to learn quantification ( through external and internal standards) by making my own samples based on toluene, hexane and isopropyl alcohol. Injection method is manual.
I started by using external standard method as this is easier to start with, I hope. My objective for these attempts is to quantify the unknown amount of target analytes of hexane and isopropyl alcohol in one unknown solution. Three external standard solutions are used to create calibration curve.
In the first couple of attempts, the results were within about 10% of error. I did the measurement again yesterday, results are completely wrong. GC peaks seem well resolved with no baseline drift.
However, calibration curve is not at all linear. Error in quantification is over 90%.
I think these are the causes of errors:
-
I thought while manual injecting a variation of 0.1 to 0.3 micro liters will be fine. PS: I am injecting about 0.5 to 1 micro Liter with 1:70 split. I think external standards cannot work with such uncertain injection volume. Injection volumes must be very precise.
-
Hexane is very hard to pipette. I am using a positive displacement pipette. Still, it tends to drip out of the pippete while pipetting. I am using a 100 to 1000 micro Liter microman positive displacement pipette.
Do you think these two are possible causes of problems? Should I try with some other chemicals other than hexane and isopropyl alcohol?
Can you please suggest some tips for my next attempt?
Thanks in advance. I don't have anyone at my work place to turn to advise. Hence, my post here, again.
Thanks again.
I started extraction after watching the video of the high guide. It was difficult to find naphtha, so I replaced it with 99% toluene and cleaned it. But the toluene smell doesn't go away. It's been almost two days, but it doesn't go away. Is it dangerous to put it in acetone before it dries completely? Or can the smell of toluene not disappear completely
Edit: here's an update https://www.reddit.com/r/simplynailogical/comments/n2nqqv/coral_chaser_lavender_syrup_have_yellowed_in_two/
Does anyone know the composition and bp of the azeotrope?
Fucking crystal meth.
Hey everyone, I kinda need help in finding the Molar enthalpy of the Combustion of Toluene.
Any help will be appreciated.
Thankyou!
https://preview.redd.it/80m4hfrrfq471.png?width=3061&format=png&auto=webp&s=78579c25453548ff24bc994c66a7dba561005d4c
Has anyone actually tried those methods written all around the web? The toluene process is based on expectation that the l-isomer will remain freebase, and d-isomer will form tartrate. This works to the extent that exactly half of the freebase is converted to tartrate, but there is no isomer separation.
The methanol method consists of equimolar amount of tartrate in methanol, expecting that the l-isomer will crash out due to minimal solubility. The mixture creates exactly the amounts described in the synthesis, 100 units will crash out, and other remains dissolved. Scientific measurements should be done to determine if the isomer is actually d-meth, but it does not want to form crystals.
Really wordy title, my apologies, but I bought the TO peeling solution and the La Roche-Posay Toleraine Ultra Moisturising Cream. Iβm completely new to this, and Iβve read that acids should be avoided when you do that kind of peeling solution. Granted, the citric acid is listed last on the ingredient list but I just want to make sure.
The ingredient list:
WATER, ISOCETYL STERATE, SQUALANE, BUTYROSPERMUM PARK, BUTTER / SHEA BUTTER, DIMETHICONE, GLYCERIN, ALUMINUM STARCH OCTENYLSUCCINATE, PENTYLENE GLYCOL, PEG-100 STEARATE, GLYCERYL STEARATE, CETYL ALCOHOL, SODIUM HYDROXIDE, ACETYL DIPEPTIDE-1, CETYL ESTER, TOLUENE SULFONIC ACID, DIMETHICONOL, ACRYLATES/C10-30 ALKYL ACRYLATE CROSSPOLYMER, CITRIC ACID
Would love any help with this! Thank you x
(BTW, Iβm only planning to have my routine comprise of using the Cerave Hydrating Cleanser as my face wash, then that LRP moisturiser, then the occasional TO peel and nothing else ahah, is this a completely bad way of going about this?)
