Thymus Puns

I am inquiring for my sister, who is 34 years, 130lbs, non-smoker and from the USA. She was recently diagnosed with the autoimmune disease myasthenia gravis, which is apparently quite rare, and causes muscle weakness. Sometimes the thymus gland is the root cause of it and is enlarged. Removal of the gland can put it into remission. However, she has an even rarer form of it called anti-MUSK where the thymus gland is not involved or effected so removal is not warranted. To the doctor's surprise, her thymus gland is enlarged (thymic hyperplasia) so the doctors said studies show that the small percentage of people with the anti-MUSK type who have thymus involvement and have it removed, show either remission or large improvements.

Considering she does not know if this would help or not, basically a total crapshoot, what are the side effects of thymus removal for an adult woman? I've read that thymus involvement for someone pre-puberty is quite bad as it can stunt growth , etc but what about an adult? I keep reading conflicting info where some say it's not needed at all and others say removing it will create an immune system nightmare and make a person prone to serious diseases as they age. Any info would be helpful!

In the book they separate them as in time, lets say T cells that don't recognize self MHC are eliminated, then those which pass the first test are then tested if they recognize self peptide. my biology teacher disagrees and says this is not scientifically proven. whom is correct?

Anyone knows where to get delicate organs like veal sweetbreads? I know wildfork in the loop sell beef sweetbreads but those are subpar to veal sweetbreads. I visited some asian markets like h-mart, joong boo, vietnamese markets(they do sell small/large intestines, hearts, livers) in lakeview, but none sell sweetbreads

So hypothetically, if you could transplant the thymus from one person to another, alongside another organ, what would happen? Would that protect the organ from the immune system? Would the immune system begin to attack the body of the recipient, but leave the organ alone?

Background:

Spouse had a freak thymoma at 17. Orange-size tumor. Fully encapsulated, stage 1B. Removed. No chemo/radiation. He's in his mid-30s now. (And still disappointed he didn't ask the surgeon to keep a sample of his thymus lol)

He's moved around the country (US) quite a bit bc of grad school, post-doc, career, so his records are scattered/some don't exist anymore. He's always done followup scans/x-rays, usually with a general practitioner, just to see if anything shows up in the staple outline where his thymus used to be.

Beyond the initial cancer-related follow-ups and periodic CTs and x-rays, he's never seen or been referred to any sort of specialist that's in tune with lack-of-thymus related issues. No one's ever keyed him in to any post-thymoma or lack-of-thymus issues.

He did randomly find out from a student health clinic in grad school, 6 years after his cancer, that he should avoid Brazil bc the yellow fever vaccine relies on the thymus. He was there for something unrelated, like a mono test. So it was very accidental that he stumbled upon a nurse practitioner whose interest was piqued, who alerted the Dr that had the time and interest to do a half hour of broad research on the spot.

With survivors of more common cancers or people with chronic conditions, there is usually some sort of specialist that's well in-tune with long-term follow-up care... Knowing what to keep an eye on as a person ages, either directly related to that disease or relating to co-morbidities/other risk factors. Like these are the long-term problems associated with X. Having X puts someone at a higher risk for Y and Z. That sort of thing.

Questions

1. What sort of long-term specialist should a thymoma survivor (or anyone that lacks a thymus) be seeing?

2. Are there any magical unicorns reading this who are well-versed in the intricacies and oddities of patients who are thymus-less? Or know someone who is? Or know how to find someone who is?

Any extra sparkly magical rainbow unicorns who have studied adult implications for pediatric thymoma survivors or are well-versed with such patients? Who, bonus, happen to be in New England?

((If I can't directly ask this, please let me know before deleting and I'll find a way to re-word))

3. Other than recurrence, what sort of things should he/his doctor be in tune with keeping an eye out for?

4. Are there any other random implications of not having a thymus? (Like the aforementioned yel

Hey everyone I modified the Anking's v9 card a few days back and edited the fields to make it more relevant.

So, essentially this is just a rip-off of Anking's v9 card. I have not removed multiple lines of code from Anking's original code, because I didn't want to completely rip-off ? And plus he deserves tons of credit for this.

I have also not replaced anking's logo from multiple fields.

I have also not added the logos of DAMS, marrow or prepladder and have kept the original logos of b&b, sketchy and pixorize,

because who wants to get a copyright infringement suit just because of a dumb logo?

Anyways, All the credit obviously goes to u/AnkingMed. I have also added two additional logos for the textbook and the image based fields.

Hoping that this helps someone out there. Signing off, Julius Seizurre.

Preview - https://imgur.com/a/VR9bZXZ

Link - Thymusv2 Card thepgproject

Also we're almost about to hit 2.5k members! So, Congratulations everybody?

P.S - I'll try posting the age old microbiology deck that I was supposed to make under 2 weeks.

Hey guys, check out this article:

Thymic development of gut-microbiota-specific T cells | Nature

Podcast discussion with the first author: https://open.spotify.com/episode/4MVABy2akbqmSoC2MW5fw0?si=q-M6MPPFSTWJIQg7CHLNUg&dl_branch=1