MyMD to commence Phase 2 trial in frailty Pharma start-up targets #sarcopenia with TNF inhibitor; claims compelling lifespan extension and frailty results in mice.

https://www.longevity.technology/mymd-to-commence-phase-2-trial-in-frailty/?utm_source=reddit&utm_medium=social&utm_campaign=frail

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πŸ‘€︎ u/philnewman100
πŸ“…︎ Dec 14 2021
🚨︎ report
For some people, muscle loss during old age can be so severe that it affects their ability to perform daily tasks. A new meta-analysis suggests that resistance training can markedly improve this condition, called sarcopenia, in older people by improving fat mass, muscle strength and performance. sapienjournal.org/resista…
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πŸ‘€︎ u/woebegonemonk
πŸ“…︎ Dec 23 2021
🚨︎ report
Relationship Between Sarcopenia and Cardiovascular Diseases in the Elderly

https://www.frontiersin.org/articles/10.3389/fcvm.2021.743710/full

> Sarcopenia has defined as a clinical syndrome associated with age-related loss such as skeletal muscle mass, strength, function, and physical performance. It is commonly seen in elderly patients with chronic diseases. Changes in lean mass are common critical determinants in the pathophysiology and progression of cardiovascular diseases (CVDs). Sarcopenia may be one of the most important causes of poor physical function and decreased cardiopulmonary function in elderly patients with CVDs. Sarcopenia may induce CVDs through common pathogenic pathways such as malnutrition, physical inactivity, insulin resistance, inflammation; these mechanisms interact.

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πŸ‘€︎ u/Valuable_Ad1073
πŸ“…︎ Jan 06 2022
🚨︎ report
Allulose Attenuated Age‐Associated Sarcopenia via Regulating IGF‐1 and Myostatin in Aged Mice [2021] onlinelibrary.wiley.com/d…
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πŸ“…︎ Nov 21 2021
🚨︎ report
For some people, muscle loss during old age can be so severe that it affects their ability to perform daily tasks. A new meta-analysis suggests that resistance training can markedly improve this condition, called sarcopenia, in older people by improving fat mass, muscle strength and performance. sapienjournal.org/resista…
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πŸ“…︎ Dec 23 2021
🚨︎ report
Rejuveron leads €15.7m series B in Rejuvenate Biomed - investment in Rejuvenate Biomed set to accelerate clinical development of its sarcopenia treatment for healthy aging. longevity.technology/reju…
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πŸ‘€︎ u/philnewman100
πŸ“…︎ Oct 12 2021
🚨︎ report
Sarcopenia and aging

Hey guys, a GP at my work was arguing with me the other day in regards to the vegan diet.

Basically he said that he read studies and younger people can do well on a vegan diet, but as we age and hit our mid 40s vegans have much larger levels of sarcopenia (loss of skeletal muscle mass).

He also said that some studies showed that protein from plant sources (I.e soy) absolutely pale in comparison to meat and that it would be inadequate.

Can anyone point me in the direction of some facts/studies to argue against this?

Thanks!

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πŸ‘€︎ u/imveganwhat
πŸ“…︎ Oct 22 2021
🚨︎ report
Mechanisms Linking the Gut-Muscle Axis With Muscle Protein Metabolism and Anabolic Resistance: Implications for Older Adults at Risk of Sarcopenia (2021) frontiersin.org/articles/…
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πŸ‘€︎ u/basmwklz
πŸ“…︎ Nov 14 2021
🚨︎ report
Allulose Attenuated Age-Associated Sarcopenia via Regulating IGF-1 and Myostatin in Aged Mice (2021) pubmed.ncbi.nlm.nih.gov/3…
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πŸ“…︎ Nov 21 2021
🚨︎ report
Advances in research on pharmacotherapy of sarcopenia (2021) onlinelibrary.wiley.com/d…
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πŸ‘€︎ u/basmwklz
πŸ“…︎ Sep 29 2021
🚨︎ report
BPTS | Biophytis Announces Promising Full Results From the SARA-INT Phase 2b Trial of Sarconeos (BIO101) in Sarcopenia at the 11th Annual International Conference on Frailty and Sarcopenia Research (ICFSR) September 29 – October 2, 2021 stocktitan.net/news/BPTS/…
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πŸ‘€︎ u/Stock_Titan
πŸ“…︎ Oct 04 2021
🚨︎ report
Prediction of sarcopenia using a battery of circulating biomarkers [2021, open-access] nature.com/articles/s4159…
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πŸ“…︎ Apr 21 2021
🚨︎ report
6 mos ago, after seeing my mom succumb to sarcopenia & osteoporosis, I started lifting 3x-4x/wk. Despite being 38, the gains came fast, but my soft layer (I’m 5’5” & 150 lbs), conceals how much muscle I’ve built. Well, today my partner noticed my back & took a photo:
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πŸ‘€︎ u/NotedHeathen
πŸ“…︎ Apr 09 2021
🚨︎ report
Animal models of sarcopenia [2020, open-access] onlinelibrary.wiley.com/d…
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πŸ“…︎ Sep 07 2020
🚨︎ report
Can prolonged stress cause sarcopenia?

[M23] i an constantly extremely stressed out and suffer from severe insomnia daily. Can this prolonged stress actually decrease your muscle tissue?

Im asking because ive noticed that my my lower right pec muscle tissue feels depleted bit more showing more bone and other areas of both pecs are filled with tissue which is abnormal to me. Otherwise i have no predisposed genetic conditions, just extremely stressed all the time. I just dont want to permanently lose muscle tissue, otherwise if its gone even exercise may not help it grow back if therrs no tissue in that area if that makes sense. Anyone know if this is possible?

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πŸ‘€︎ u/cao0987
πŸ“…︎ Jun 17 2021
🚨︎ report
Sarcopenia is poor risk for unfavorable short- and long-term outcomes in stage I non-small cell lung cancer docwirenews.com/abstracts…
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πŸ‘€︎ u/montaukwhaler
πŸ“…︎ Mar 14 2021
🚨︎ report
Nutritional Supplements to Support Resistance Exercise in Countering the Sarcopenia of Aging pubmed.ncbi.nlm.nih.gov/3…
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πŸ‘€︎ u/aroedl
πŸ“…︎ Jul 15 2020
🚨︎ report
Prognostic Implication of Baseline Sarcopenia for Length of Hospital Stay and Survival in Patients With Coronavirus Disease academic.oup.com/biomedge…
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πŸ‘€︎ u/Sorin61
πŸ“…︎ May 08 2021
🚨︎ report
Sarcopenia and Muscle Aging: A Brief Overview e-enm.org/journal/view.ph…
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πŸ‘€︎ u/basmwklz
πŸ“…︎ Jan 11 2021
🚨︎ report
Rapamycin may suppress muscle aging and prevent sarcopenia medicalxpress.com/news/20…
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πŸ‘€︎ u/izumi3682
πŸ“…︎ Sep 10 2020
🚨︎ report
Review of sarcopenia in aging

https://www.e-enm.org/m/journal/view.php?doi=10.3803/EnM.2020.405

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πŸ‘€︎ u/Dragkkon
πŸ“…︎ Feb 07 2021
🚨︎ report
Exercise rescues mitochondrial coupling in aged skeletal muscle: a comparison of different modalities in preventing sarcopenia (Feb 2021) translational-medicine.bi…
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πŸ‘€︎ u/basmwklz
πŸ“…︎ Feb 21 2021
🚨︎ report
How to know, measure & evaluate your Visceral Fat & Sarcopenia: What it Is & How To Eliminate Each. - Dr Sean O'Mara recommends a keto zerocarb carnivore diet to resolve visceral fat. youtube.com/watch?v=TMgjS…
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πŸ‘€︎ u/dem0n0cracy
πŸ“…︎ Oct 17 2020
🚨︎ report
Rapamycin may suppress muscle aging and prevent sarcopenia medicalxpress.com/news/20…
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πŸ‘€︎ u/MichaelTen
πŸ“…︎ Sep 10 2020
🚨︎ report

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