MDMA/ecstasy & psilocybin use is associated with a lower risk of depression - Findings from a Harvard observational study of 213,437 US adults. journals.sagepub.com/doi/…
πŸ‘︎ 2k
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πŸ‘€︎ u/drdrugsandbrains
πŸ“…︎ Jan 06 2022
🚨︎ report
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching cureus.com/articles/82162…
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πŸ‘€︎ u/BrazilRedPill
πŸ“…︎ Jan 15 2022
🚨︎ report
MDMA/ecstasy & psilocybin use is associated with a lower risk of depression - Findings from a Harvard observational study of 213,437 US adults. journals.sagepub.com/doi/…
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πŸ‘€︎ u/drdrugsandbrains
πŸ“…︎ Jan 06 2022
🚨︎ report
Landmark US observational study pre-print (n=3,962): Covid-19 is easily treatable with early ambulatory treatment, nearly entirely eradicating the risk of hospitalization and death. Covid loss of lives is only due to medical response mismanagement. twitter.com/Covid19Crushe…
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πŸ‘€︎ u/veganmark
πŸ“…︎ Jan 16 2022
🚨︎ report
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching cureus.com/articles/82162…
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πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jan 18 2022
🚨︎ report
The Influence of Cannabis and Alcohol Use on Sexuality: An Observational Study in Young People (18–30 Years) β€” Sexual function in young people who use cannabis and alcohol more frequently was shown to be better than in those who do not use either [2022] mdpi.com/2227-9032/10/1/7…
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πŸ“…︎ Jan 19 2022
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(PDF) Ivermectin Prophylaxis Used for COVID-19 Reduces COVID-19 Infection and Mortality Rates: A City-Wide, Prospective Observational Study of 220,517 Subjects Using Propensity Score Matching. researchgate.net/publicat…
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πŸ‘€︎ u/frankiecwrights
πŸ“…︎ Jan 05 2022
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Drexit: Understanding why junior doctors leave their training programs to train overseas: An observational study of UK physicians onlinelibrary.wiley.com/d…
πŸ‘︎ 148
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πŸ‘€︎ u/MedicSoonThx
πŸ“…︎ Nov 14 2021
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Indirect effects of the covid-19 pandemic on childhood infection in England: population based observational study bmj.com/content/376/bmj-2…
πŸ‘︎ 12
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πŸ‘€︎ u/squidwardsabz
πŸ“…︎ Jan 18 2022
🚨︎ report
Ivermectin as a Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching. Massive reduction in infections and hospitalization. cureus.com/articles/82162…
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πŸ‘€︎ u/StonksAndBlondz
πŸ“…︎ Jan 18 2022
🚨︎ report
(PDF) Ivermectin Prophylaxis Used for COVID-19 Reduces COVID-19 Infection and Mortality Rates: A City-Wide, Prospective Observational Study of 220,517 Subjects Using Propensity Score Matching. researchgate.net/publicat…
πŸ‘︎ 3
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πŸ‘€︎ u/SftwEngr
πŸ“…︎ Jan 10 2022
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Efficiency of primary spine care as compared to conventional primary care: a retrospective observational study at an Academic Medical Center pubmed.ncbi.nlm.nih.gov/3…
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πŸ‘€︎ u/Kibibitz
πŸ“…︎ Jan 12 2022
🚨︎ report
MDMA/ecstasy & psilocybin use is associated with a lower risk of depression - Findings from a Harvard observational study of 213,437 US adults. journals.sagepub.com/doi/…
πŸ‘︎ 83
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πŸ‘€︎ u/drdrugsandbrains
πŸ“…︎ Jan 06 2022
🚨︎ report
Real-world effectiveness of the mRNA-1273 vaccine against COVID-19: Interim results from a prospective observational cohort study sciencedirect.com/science…
πŸ‘︎ 220
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πŸ‘€︎ u/afk05
πŸ“…︎ Nov 30 2021
🚨︎ report
Observational Study from Department of Psychology, University of British Columbia: Adults who microdose psychedelics report health-related motivations and lower levels of anxiety and depression compared to non-microdosers. nature.com/articles/s4159…
πŸ‘︎ 274
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πŸ‘€︎ u/shroomscout
πŸ“…︎ Nov 18 2021
🚨︎ report
Observational study from Denmark indicates that the mRNA vaccines protect for a few weeks only but then SIGNIFICANTLY AUGMENT Omicron infectivity. Is the immune system actually harmed, creating shot repetition dependency (with unknown long-term safety)? twitter.com/Covid19Crushe…
πŸ‘︎ 30
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πŸ‘€︎ u/veganmark
πŸ“…︎ Dec 23 2021
🚨︎ report
Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test sciencedirect.com/science…
πŸ‘︎ 41
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πŸ‘€︎ u/icloudbug
πŸ“…︎ Dec 21 2021
🚨︎ report
Vegetable fats associated with lower stroke risk, animal fats with higher stroke risk in long term observational study of 100k health professionals medscape.com/viewarticle/…
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πŸ“…︎ Nov 18 2021
🚨︎ report
My Forearm Observational Study
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πŸ‘€︎ u/GoldSeafarer
πŸ“…︎ Dec 12 2021
🚨︎ report
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching cureus.com/articles/82162…
πŸ‘︎ 4
πŸ’¬︎
πŸ“…︎ Jan 17 2022
🚨︎ report
MindMed, through HealthMode, just completed an observational study

Feasibility of Passive Data Collection in Dementia Subjects With Agitation

https://www.clinicaltrials.gov/ct2/show/NCT04413851

Brief Summary:

This is a multi-center, observational, feasibility study, to evaluate long term passive data collection, data quality, and user experience of HealthMode Agitation (Apps) to collect motion, location, physiological, and audio data; and eCOA and EMA responses with mobile devices (iPhone, Apple Watch).

The purpose of this study is to evaluate and improve HealthMode Apps data collection and usability in subjects experiencing agitation in the context of dementia.

edit: note, it had 1 participant

πŸ‘︎ 61
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πŸ‘€︎ u/tomski1981
πŸ“…︎ Dec 18 2021
🚨︎ report
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching cureus.com/articles/82162…
πŸ‘︎ 6
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πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jan 18 2022
🚨︎ report
Robert Malone MD - In peer reviewed prospective observational study of 1,072,313 patients, UK group unable to tell the difference between vaccine effects and COVID-19. Disentangling post-vaccination symptoms from early COVID-19 twitter.com/RWMaloneMD/st…
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πŸ‘€︎ u/veganmark
πŸ“…︎ Dec 08 2021
🚨︎ report
The relationship between persistent organic pollutants and attention deficit hyperactivity disorder phenotypes: Evidence from task-based neural activity in an observational study of a community sample of Canadian mother-child dyads pubmed.ncbi.nlm.nih.gov/3…
πŸ‘︎ 82
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πŸ‘€︎ u/gintrux
πŸ“…︎ Dec 25 2021
🚨︎ report
Ivermectin Prophylaxis Used for COVID-19: A Citywide, Prospective, Observational Study of 223,128 Subjects Using Propensity Score Matching cureus.com/articles/82162…
πŸ‘︎ 7
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πŸ‘€︎ u/SNM_2_0
πŸ“…︎ Jan 16 2022
🚨︎ report
The rich and precise dataset of the large Itajai observational study (n=220,517) - that the authors will make public- allows precise assessment of the dose dependent effect of the treatment. It is an extremely strong evidence of causality and therapeutic effect. twitter.com/Covid19Crushe…
πŸ‘︎ 13
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πŸ‘€︎ u/veganmark
πŸ“…︎ Jan 07 2022
🚨︎ report
Population-wide Observational Study in Brazil: Prophylactic Use of Ivermectin Reduces COVID-19 Mortality, Hospitalization & Infection β€œOut of two study cohorts of 3,034 COVID-19 infected patients, the regular use of ivermectin led to a 68% reduction in COVID-19 mortality.
πŸ‘︎ 17
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πŸ‘€︎ u/parkstar86
πŸ“…︎ Jan 07 2022
🚨︎ report
Sperm quality and absence of SARS-CoV-2 RNA in semen after COVID-19 infection: a prospective, observational study and validation of the SpermCOVID test

https://www.sciencedirect.com/science/article/pii/S0015028221021567

Result(s)

SARS-CoV-2 RNA was not detected in semen during the period shortly after infection nor at a later time. Mean progressive motility was reduced in 60% of men tested shortly (<1 month) after COVID-19 infection, 37% of men tested 1 to 2 months after COVID-19 infection, and 28% of men tested >2 months after COVID-19 infection.

Mean sperm count was reduced in 37% of men tested shortly (<1 month) after COVID-19 infection, 29% of men tested 1 to 2 months after COVID-19 infection, and 6% of men tested >2 months after COVID-19 infection. The severity of COVID-19 infection and the presence of fever were not correlated with sperm characteristics, but there were strong correlations between sperm abnormalities and the titers of SARS-CoV-2 IgG antibody against spike 1 and the receptor- binding domain of spike 1, but not against nucleotide, in serum. High levels of antisperm antibodies developed in three men (2.5%).

Conclusion(s)

Semen is not infectious with SARS-CoV-2 at 1 week or more after COVID-19 infection (mean, 53 days). However, couples with a desire for pregnancy should be warned that sperm quality after COVID-19 infection can be suboptimal. The estimated recovery time is 3 months, but further follow-up studies are under way to confirm this and to determine if permanent damage occurred in a minority of men.

πŸ‘︎ 11
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πŸ‘€︎ u/marksistbarstard
πŸ“…︎ Dec 22 2021
🚨︎ report
Durability of mRNA-1273 against COVID-19 in the time of Delta: Interim results from an observational cohort study medrxiv.org/content/10.11…
πŸ‘︎ 10
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πŸ‘€︎ u/icloudbug
πŸ“…︎ Dec 14 2021
🚨︎ report
Association between dietary zinc intake and metabolic syndrome. A meta-analysis of observational studies frontiersin.org/articles/…
πŸ‘︎ 4
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πŸ‘€︎ u/dem0n0cracy
πŸ“…︎ Jan 08 2022
🚨︎ report
Effectiveness of a third dose of the BNT162b2 mRNA COVID-19 vaccine for preventing severe outcomes in Israel: an observational study thelancet.com/journals/la…
πŸ‘︎ 36
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πŸ“…︎ Nov 15 2021
🚨︎ report
Comparative Effectiveness of BNT162b2 and mRNA-1273 Vaccines in U.S. Veterans: A Pfizer and Moderna Prospectivr Observational Study nejm.org/doi/full/10.1056…
πŸ‘︎ 40
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πŸ‘€︎ u/redman657529
πŸ“…︎ Dec 04 2021
🚨︎ report
Safety, health improvement and well-being during a 4 to 21-day fasting period in an observational study including 1422 subjects

https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0209353

Abstract

Only few studies document longer periods of fasting in large cohorts including non-obese participants. The aim of this study was to document prospectively the safety and any changes in basic health and well-being indicators during Buchinger periodic fasting within a specialised clinic. In a one-year observational study 1422 subjects participated in a fasting program consisting of fasting periods of between 4 and 21 days. Subjects were grouped in fasting period lengths of 5, 10, 15 and 20Β±2 days. The participants fasted according to the Buchinger guidelines with a daily caloric intake of 200–250 kcal accompanied by a moderate-intensity lifestyle program. Clinical parameters as well as adverse effects and well-being were documented daily. Blood examinations before and at the end of the fasting period complemented the pre-post analysis using mixed-effects linear models. Significant reductions in weight, abdominal circumference and blood pressure were observed in the whole group (each p<0.001). A beneficial modulating effect of fasting on blood lipids, glucoregulation and further general health-related blood parameters was shown. In all groups, fasting led to a decrease in blood glucose levels to low norm range and to an increase in ketone bodies levels (each p<0.001), documenting the metabolic switch. An increase in physical and emotional well-being (each p<0.001) and an absence of hunger feeling in 93.2% of the subjects supported the feasibility of prolonged fasting. Among the 404 subjects with pre-existing health-complaints, 341 (84.4%) reported an improvement. Adverse effects were reported in less than 1% of the participants. The results from 1422 subjects showed for the first time that Buchinger periodic fasting lasting from 4 to 21 days is safe and well tolerated. It led to enhancement of emotional and physical well-being and improvements in relevant cardiovascular and general risk factors, as well as subjective health complaints.

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πŸ’¬︎
πŸ“…︎ Dec 26 2021
🚨︎ report
Clinical characteristics with inflammation profiling of Long-COVID and association with one-year recovery following hospitalisation in the UK: a prospective observational study medrxiv.org/content/10.11…
πŸ‘︎ 16
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πŸ‘€︎ u/JaneSteinberg
πŸ“…︎ Dec 15 2021
🚨︎ report
COVID-19 Vaccine Perceptions in the Initial Phases of US Vaccine Roll-out: An Observational Study on Reddit [preprint] europepmc.org/article/ppr…
πŸ‘︎ 2
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πŸ‘€︎ u/MFA_Nay
πŸ“…︎ Jan 08 2022
🚨︎ report
Healthy body weight : β€œObservational surveys and intervention studies have shown that excess body fatness is the major environmental cause of type 2 diabetes, and that even a minor weight loss can prevent its development in high-risk subjects.” pubmed.ncbi.nlm.nih.gov/1…
πŸ‘︎ 5
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πŸ‘€︎ u/MBKFade
πŸ“…︎ Jan 04 2022
🚨︎ report
Population-wide Observational Study in Brazil: Prophylactic Use of Ivermectin Reduces COVID-19 Mortality, Hospitalization & Infection trialsitenews.com/populat…
πŸ‘︎ 2
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πŸ‘€︎ u/parkstar86
πŸ“…︎ Jan 07 2022
🚨︎ report
Time of Day of Vaccination Affects SARS-CoV-2 Antibody Responses in an Observational Study of Health Care Workers journals.sagepub.com/doi/…
πŸ‘︎ 37
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πŸ‘€︎ u/tonic613
πŸ“…︎ Dec 07 2021
🚨︎ report
An observational study of breakthrough SARS-CoV-2 Delta variant infections among vaccinated healthcare workers in Vietnam thelancet.com/journals/ec…
πŸ‘︎ 11
πŸ’¬︎
πŸ‘€︎ u/isommers1
πŸ“…︎ Nov 09 2021
🚨︎ report
Drexit: Understanding why junior doctors leave their training programs to train overseas: An observational study of UK physicians onlinelibrary.wiley.com/d…
πŸ‘︎ 30
πŸ’¬︎
πŸ‘€︎ u/MedicSoonThx
πŸ“…︎ Nov 14 2021
🚨︎ report
Muscle strength and muscle mass as predictors of hospital length of stay in patients with moderate to severe COVID-19: a prospective observational study pubmed.ncbi.nlm.nih.gov/3…
πŸ‘︎ 100
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πŸ‘€︎ u/dpjoachim
πŸ“…︎ Sep 27 2021
🚨︎ report
Largest real-world study of third dose mRNA COVID-19 vaccine effectiveness for preventing severe outcomes in Israel: an observational study thelancet.com/journals/la…
πŸ‘︎ 58
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πŸ‘€︎ u/geoxol
πŸ“…︎ Oct 30 2021
🚨︎ report

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