Has anyone ever had an eye angiography? Anyone know anything about fluorescein? They had to inject intravenously for eye angiography.
In the 9th edition of Kanski’s ophthalmology
It says “Fluorescein angiography (FA) is never needed these days. However, if undertaken it typically shows a round hyperfluorescent window defect with a hyperfluorescent centre”
Is this a typo as all the images I see have hypofluorescent centre or am I missing something
Eg: https://www.aao.org/image/cone-dystrophy-8
I am in need of some (could probably get away with under 1g) fluorescein diacetate. I don't want to buy it as it is quite expensive and only avaible from fisher and sigma compared to fluorescein, which is cheap. I also thought it would be somewhat fun to make it instead of buying it.
I am not a chemist but my senses tell me that it should be possible to make it from fluorescein and acetic acid by just heating it, forming the ester bonds. Won't the acetic acid also react in other ways, if yes to which degree and how hard could it be to separete? I understand that some monoacetate will form if I don't let the reaction go to completion.
The interesting part is that I have found nothing about the synthesis. Either it is that simple and I am just overthinking it or it is just very unusual.
I am not sure if this falls under the category "lab questions", if it does, I will delete it.
How long does it take the dye to reach the eye, assuming it is injected in the hand? And is there an amount of time that if you saw would be concerning? Mine took 1 min 7 secs, which the nurse doing the injection and the tech doing the photos both thought was longer and at first they thought they missed the vein. It kind of has me worried, the last few times they have done it has not taken that long.
Hi I’ve recently shifting to a primary care practice setting.
On and off I see eye issues at my place.
I am developing a basic enough understanding of eye issues that I don’t really want to send out every single eye thing (which many physicians do because they’re not comfortable)
But I don’t really have much experience and I’m tempted to do the works for every patient with an eye issue.
One thing that has come up is a question of when I should be doing fluorescein staining. I’ve seen a variety of practice and I’m not sure what’s right.
Do you routinely stain:
All ocular trauma regardless of how mild the symptoms seem to be?
All red eyes? (Are you confident just with a torchlight to exclude keratitis? I know some physicians call every red eye conjunctivitis but surely one day we’re gonna miss a keratitis outside the visual axis)
Do you also routinely evert the eyelids of every red eye? Seems like we should but hardly anyone does this.
Would be nice if The Eye guys can comment and if we can compare this to what the primary care/ ED guys do.
There’s got to be a balance because primary care is busy and IDK if it will be frowned upon if I waste time staining all the red eyes that are probably conjunctivitis.
Thanks!
