Anaphylaxis Puns

As far as I’m aware anaphylaxis is pretty much death without an epipen? Unless I’ve been misinformed.

Like the girl who had the panini from Pret A Manger with sesame seeds on and died on the plane.

I’m confused as to how they get diagnosed with this and need to know. Your throat either closes up and you can’t breathe, or it doesn’t. You can’t exactly fake that can you?

Edit: I guess I forgot people can just lie to the internet lol.

As per https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8251011/
Also, there is also this additional "small" issue related to PEG injections - https://pubmed.ncbi.nlm.nih.gov/31526095/

On the other hand, Inovio's vaccines consist only of water and DNA plasmids, no preservatives no adjuvants nothing else. This is one of the reasons the vaccine safety profile is great.

As a side note, just a thought...Since PEG is fundamental to the mRNA vaccine delivery method and since our immune system can be sensitized to PEG if it is exposed to it multiple times. Is it possible that because they are injecting billions of people with this stuff, including children, they can effectively sensitize a huge amount of people to PEG? This would be quite unfortunate for the other therapies in their pipelines since they would not be able to deliver them with the same method because of the potential allergic reactions and inventing a new delivery method for the fragile mRNA molecule is far from trivial.

Just a question because I’ve had these issues for a while and I’ve gotten them mostly under control by maintaining a stric elimination diet but sometimes I still swell up like a little grape tomato randomly and I start feel like I can’t breathe at all/have to pour water down my throat constantly to maintain an open airway. It’s really similar to when my mother accidentally eats anything that might have touched a nut and needs to put off the shock until the EMTs get there but no one ever believes me that it’s happening.

So I have POTs and EDS, been diagnosed for 8 years. I strongly suspect MCAS. I've had many anaphylaxic episodes in the past couple years. But this was a weird one today. After I ate my gums got really swollen and painful and my throat started itching just a little bit. I've also had hives on my neck for a couple days now. But I was wondering if anybody else thought this would technically count at anaphylaxis. I've had 2 very clear anaphylaxis episodes this week already (Sunday and yesterday) I'm trying to keep track so I can tell the rheumatologist I'm going to be seeing in a couple months. Any other advice for me would be great too! Thanks

I have a rough idea what the difference is, but the internet isn't a reliable source and tends to add fluff or contradict itself. Can I get some key differences between anaphylaxis and Allergic reaction please.

👋🏼 Just checking in re: anaphylaxis from Xolair. I had my third Xolair injection yesterday and had a systemic reaction- itchy ears, wheezing, high blood pressure, couldn’t think clearly and was given an epi-pen at the infusion center.

The nurse and my doctor are going to collaborate on an “out of the box” administration with Xolair going forward (because it is really helping me)… they mentioned pre-meds via IV.

Has anyone tried Xolair again after an anaphylactic reaction to it? How did it go?

I am 32 and just experienced my very first allergic response. And I honestly feel like no one is taking it seriously aside from me.

Quick background: Never had any known allergies to food or meds. Then 2 weeks ago I had a beautiful 12 course meal with lots of unique ingredients including 3 different types flower petals; 4 hours later my lips were huge and swollen, my eyes were swollen, my throat was closing up, so I rushed to the emergency room.

They got me in immediately, and administered Epi as well as IV steroids. They observed me for a few hours, then released me with an Rx for more steroids and my own EpiPen, as well as them telling me I should go see an allergist.

Insurance wouldn't approve the Epi, so I figured going to an allergist and having them put the rx through would show it's needed. Allergist told me he'd do that for me, but wouldn't do an allergy panel since I'm not allergic to any of the 8 "big" allergy foods.

I feel terrified that I'm going to come across something I'm unknowningly allergic to and won't have an epipen, and have a worse reaction the 2nd time and DIE.

Does anyone have any similar stories in regards to an allergist denying a test/panel? Am I overreacting? Should I just go get a 2nd opinion? All advice is very appreciated.

hi, I've been suffering from dysphagia for about a month now reason is still unknown, got diagnosed with esophagus peptic ulcer but my doctor said this shouldn't interfere with swallowing, I've been living on juices since and seing other doctors in the hope to find why I'm unable to swallow solid food.

In the mean time I've been taking proton pump inhibitor (omperazole) intravenously however I think I'm allergic to it or something else I'm not really sure.

There are nights where I feel my throat is tight and dry and like I'm about to get my airways blocked and other nights it's less severe and some nights I will be just fine, my symptoms like in the title are just tight and dry throat no other allergy symptoms. what makes things weird is that my symptoms starts at almost the same time around 9pm regardless of the time I took the medcine or drink the last juice of the day there are days where I had the symptoms even though I didn't take the medicine and days where I had them even though I didn't eat anything at all except water

one more note the symptoms get better when I take a shot of methylprednisolone

another note: I developed an oral thrush since my condition started probably due to reduced immunity

Does anyone in here have experience with food dependent exercise induced anaphylaxis?

I recently underwent allergy testing (I’m NOT allergic to any of the common allergens but AM allergic to dust mites so I have to stay away from shellfish), and my allergist warned me about this condition (not in a very sensitive way, and she sort of demonized runners for running, and for eating carbs all the time).

But apparently, you don’t necessarily have to be allergic to the food to have a FDEIA reaction ? And sometimes being allergic to dust mites and having asthma (both are my case) can make it worse ?

Anyway the way she explained it was really murky and she basically made me feel like the best solution is to stop running or not eat for 4-6 hours before running.

With my metabolism, I usually eat every 3-4 hours, plus I have long runs where I need to eat something in the middle. Now I’m afraid of having a reaction to foods I’m NOT allergic to, if I eat them too close to running or during a long run.

Anyone dealt with this? Guidance?

I (24F) tested positive for Covid 2 days ago. I was able to get an appointment to get an antibody infusion. Within 5 minutes, my body went into anaphylactic shock. My throat closed up, my whole body swelled up, and the nurses had to give me an epipen immediately. Posting for awareness. I’m not allergic to anything. Should’ve just tried to ride out the virus. I spent the whole day in the ER

I ask because I do have food allergies but I also have anxiety. And my anxiety makes me feel like my throat is closing a lot. And of course that makes me more anxious thinking oh no I’m going into anaphylaxis. But it’s never accompanied by hives or itching or any other symptom. Just a weird lump behind my Adam’s apple or low near my collar bone.

I’m terrified I won’t know the difference and will mistake anaphylaxis for anxiety. How will I know? Does it hurt? Do you just know?

Edit: to add. This sensation lasts sometimes literal hours so I’m assuming anaphylaxis based throat closing hits faster than that?

Hi everyone. I’m looking for some support and to find out what to expect in the coming days.

I’ve always been allergic to nuts and peanuts and had anaphylaxis as a kid, but I got good at avoiding problematic food as an adult and also went through CBT therapy to conquer anxiety about the allergies and some other issues. I convinced myself I didn’t have anaphylaxis anymore and that maybe I’d outgrown it.

Long story short my husband’s stepmom insisted last night that I try pumpkin cheesecake from a local bakery. I avoid foods from bakeries because of cross-contamination but I ate it anyway… she’d checked to make sure it was safe and they assured her it was. Anyway, I knew immediately. It felt like I swallowed a handful of fire ants.

I had no epi-pen so I used my CBT skills to stay calm and keep myself breathing and then induced vomiting. In the meantime my chest started to feel like it was filled with a fucking blimp. I threw up and more for a solid half hour along with the chest tightness. At this point I didn’t even know if I was itching because everything else was so overwhelming.

Confirmed at least via phone with my allergist this morning that I should’ve had an EP and used it (puking and a fuckton of Benadryl saved me). I will be going on a course of prednisone and obviously I bought an epi-pen. What else should I expect after this episode? Have people dealt with trauma symptoms? How can you start being comfortable with food again?

Any support and commiseration appreciated. Thank you!

Age: 44

Sex: Female

Height: 5'8"

Weight: Average :)

Race: White

Duration of complaint: twice over the last four-ish months

Location: Ohio, USA

Any existing relevant medical issues: Allergies to corn

Current medications: 75mg Setroline

Details: A couple of months ago, my wife was cleaning out the fridge and sniffed a container that had some mold in it. Bam - instant reaction, throat closed, choking, coughing, what I could only surmise was anaphylaxis as a reaction to it. It went away after about twenty minutes. We thought nothing it.

However, the same thing happened to her last night, in the middle of the night, and while she was asleep. About 3:00am or so. Scared us both, because this time, there seemed to be no rhyme or reason to it.

Is this normal? It has never happened before spontaneously.

Thanks in advance! Oh, and yes - we're going to get her to the doctor as soon as a spot opens up, but thought I'd ask here, too.

I was one of the few who went into anaphylactic shock after my first Moderna dose in the spring. Never happened to me before, scary, but I carry 2 EpiPens on me now.

Following strict orders from my allergist, I cannot receive any of the vaccines currently available in the U.S. Allergist was hopeful that NovaVax would be out in September of this year for me to receive, but still no signs of U.S. approval.

Does anyone know anything about what others in my situation are doing? It’s been so frustrating desperately wanting to be fully vaxxed yet there is no official advice for people who have no choice but to remain unvaccinated.

I have a new thing where I’m scared of having a life threatening allergic reaction to new foods and medicines. Sometimes even foods I’ve eaten before because I know allergies can develop.

Keep in mind I have no known allergies as of now and my family doesn’t have any either. So this fear is definitely irrational. I think it ties into the panic attacks I’ve been having where it feels like my throat is closing up (even though it’s not) or that I’m not getting enough air.

Idk what the point of this is, just ranting because it’s 3am and my period cramps are absolutely killing me but I’m scared to take ibuprofen.

lmao i hate this

Does the word anaphylaxis usually imply anaphylactic shock? Or is it simply used to describe a severe allergic reaction?

Hey everyone,

I’m a 21 year old male who became allergic to exercise two years ago. I grew up very active and lost a full athletic scholarship because of my condition.

Any advice for how I can beat this allergy?

My throat closed in last night due to my allergy shots, and today my voice is BAD. I've been told that I sound like a 60 year old smoker, a microwave, and CORPSE 🤣

Last night I ended up at the ER with an anaphylactic reaction closing up my throat. Two epipens steroids and Benadryl got it under control so I was released and I woke up this morning feeling okay but now I feel so drained. It's been several years since my last reaction just curious to know how everyone else felt after a moderate to severe reaction but that didn't result in a hospitalization. And is there anything you can do to feel better?

Hi

I am looking for some advice/guidance on a case study.

60 year old male experienced allergic reaction following a bee sting,

had an unwitnessed ?collapse following the initial sting, followed by two tonic clonic seizures resulting in a head injury, or head injury from collapse causing seizures.

Three seizures with crew lasting 20 seconds each across a 20 minute time period, with no other post ictal symptoms only amnesia.

Observations on arrival:

urticaria and erythema over back, neck and abdomen.

GCS15, RR 20, HR60 with bradycardic runs lowest of 30 immediately after seizure but self resolving following fluids.

BP 90 Systolic, saturations 92, desaturated after 2nd seziure to 86.

Oxygen administered, IV access gained with administration of fluids to get bp 110systolic.

Chlorphenamine initial drug over adrenaline (4 clinicians on scene for extrication) and was the first readily available drug - administered IV.

critical care contacted for advice on which drugs can be given together (?atropine, ?diazepam, ?adrenaline).

Critical care advised OK to withhold IM adrenaline.

Pt GCS 15, with observations within normal range following initial drug administration, and urticaria/erythema had resolved.

Question:

Although patient was likely to have been experiencing anaphylaxis would IM adrenaline still be indicated even though patient now haemodynamically stable?

Any advise - this was a patient my mentor had been to in the past and was running through case studies with me to see what I would do.

NB. I am a paramedic student in the UK. Apologies if posted incorrectly. thank you :)

Edit:

Thank you everyone who's taken the time to reply and give your views on your treatment for the patient. As a student very beneficial to me to see other peoples way of thinking and the added info some people have given.

I recently ate some shellfish and face ballooned up big time. Was wondering if someone dies that way would the swelling go down after or does it stay like that?

One week after the Covid-19 vaccination campaign was launched, Vietnam has reported its first case of serious anaphylaxis caused by the AstraZeneca shot.

I know there is a protocol in place for vaccine allergic reactions but how often have you seen it actually happen? In particular, the flu shot. How unlikely would it be for someone to have a reaction when they have been previously vaccinated with no issues?

I’m avoiding foods. I’m scared to bleach my hair. I’m scared to clean or craft with any chemicals.

I feel like my anxiety can literally mimic any symptom, so I can easily worry myself into thinking I’m itchy or my throat is closing.

I feel like I’ll never get over this fear because anaphylaxis is very real and unavoidable, and happens to many people. Also I live alone, so if I do experience it, I’ll definitely die. I’d probably wait too long before I call 911, thinking I’m just having another anxiety attack, but then I’ll realize it’s not a false alarm, and it’ll be too late.😟

This is a very hypothetical post and may also be clinically insignificant. If a patient has an allergic reaction to rocuronium when you give it, should you reverse it with sugammadex as part of the treatment plan? This being after the patient is stable and the necessary interventions (airway securement, epinephrine, antihistamine, etc.). Also, would you even reverse if this happens?

My thought process on this as someone who is in training, is that following the necessary steps to ensure the patient is safe, would the sugammadex-rocuronium complex still cause the IgE- immunity response that the drug would.

Thank you for your time in advance.

I had never had a serious reaction and didnt have an epi pen. i was home alone. When i realized what was happening by instinct I grabbed the Zyrtec and chewed three. then jumped in a cold shower and hoped they'd kick in. Within 5 minutes I felt ok enough to get to the ER and they didn't need to give me an epi pen. The doctor said biting down and swallowing the pills saved my life. It's the same concept behind biting aspirin if you're having a heart attack. The cheeks and mouth actually absorb it first - before moving down through the esophagus.

So if you are ever in a place where you dont have an epi pen, BITE DOWN and CHEW your antihistamines. iT will buy time until you can get to a hospital.

Hi everyone,

I’m a 21 year old male who is allergic to exercise. I grew up extremely active and lost a full athletic scholarship due to my conduction, EIA.

Is there anyone else here who has/had the same condition? Any advice or solutions?

Any help would be greatly appreciated.