Onychomycosis Puns

Griseofulvin is used to treat dermatophyte-related {{c1::onychomycosis (nail fungus)}}

The oral antifungal drug {{c1::Terbinafine}} is used to treat {{c2::onychomycosis (dermatophyte infection of nails)::what dermatophyte infection}}

For more severe Tinea infections or persistent Onychomycosis (manifestations of dermatophytes), oral {{c1::Griseofulvin}} is used

Is this just semantics or is there an actual difference in the use of griseofulvin and terbinafine for onychomycosis?

Age: 54, Height: 6', Weight: 240lbs, Male, meds: nexium, non-smoker, no medical issues, has been here two weeks, right foot, second toe (next to big toe) - please see photo in comments

Health (onychomycosis) Im a woman who had been suffering with this type of fungal infection and this has been affecting my life terribly. Im a clean and healthy person but once I borrowed my dad’s nail clipper and since then its has been getting worse and worse. I tried a lot of products, laser treatment and o even cut and file to see if it would go away. Honestly I cant even have sex without socks anymore, I refuse to shower with my boyfriend just because of my feet. I need help with it PLEASE

Hey All,
Image here - https://imgur.com/a/DipecS6

Does this look like onychomycosis? (Left foot) - i've trimmed as much as i can from the toe but anything more and it hurts.
Thanks

My insurance is not accepting my medical claim concerning an onychomycosis treatment I am using. Their position is that the onychomycosis I have is related to my psoriasis (a preexisting condition).

They say that 50% - 70% of the persons with psoriasis develop onychomycosis.

Is this data correct?

Thanks for your help.

32, Female, non-smoker

A little backstory: I've had this issue for a decade now. I noticed yellowing on the edges of my big toenails when I was about 20-21. Embarrassed, I never went to the doctor about it. I tried home remedies over the years all while keeping it a secret from family and friends. It seemed to only affect my big toenails (I had a history of ingrown nail problems between the ages of 8-13 and the nail would form a horizontal line across the whole nail.) When I was 27, it was bad enough that I went to Dermatologist #1. He didn't even do a culture and chalked it up to genetics. I was given some nail conditioning cream and tried that for about half a year as my nails got worse. I then went to Dermatologist #2 who gave me Jublia, which was insanely expensive for me, so I stopped using it after two months--not long enough to see results. Another few years went by of trying home remedies to no avail. I decided to try Dermatologist #3. By this time, my big toes were so dystrophic, they caused a lot of pain and started to grow crooked. My other toenails also started looking slightly yellow, although nowhere nearly as bad as my big nails. She tried taking a culture of my big nails... nothing was found. I went back a few months later and did another culture. This time, aspergillus was found. Per her instruction, I debrided my big toenails with 40% urea and was able to cut off several layers of thickened nail. I decided to also give in and try oral terbinafine. This brings us to last year.

I tried oral terbinafine for about a month. Turns out, I am allergic to it. I developed hives and was instructed by my dermatologist to stop taking it. We discussed other options, including itraconazole. I don't really want to take that as it isn't as effective as terbinafine and not worth the side effects. This was about a year ago. Since then, I have been using natural topical remedies such as tea tree oil, clove oil, Vicks VapoRub, etc. It doesn't seem to be going away, however.

Since my culture results revealed aspergillus, I've been researching different topical antifungal medicines that are powerful against aspergillus specifically. I've come across topical amphotericin B. However, it appears I can't get it in the US (or not sure what marketing name to look for.)

Does anyone have any knowledge about what this would be or why it isn't available in the United States? Also, I would appreciate any other suggestions people may have for onychomycosis caused by a

Hi all. I have seen an abundance of anecdotal reports of onychomycosis (toenail fungus) resolving or improving after following the ketogenic diet for several months. One should rightly be sceptical of anecdotal reports, but when the same effect is reproduced over and over again, you begin to suspect something is going on.

To me, it seems plausible that keto can improve onychomycosis. Fungus, to my knowledge, has a glucose metabolism -- it feeds off it. There might also been a beneficial immune-system effect: you're not bombing your system with inflammatory foods, so the immune system can go and take care of what is needed.

Do you think these mechanisms make sense? If not, why? And can you think of any others?
Or do you think the benefits of keto on onychomycosis and fungal infections generally (like athlete's foot) are exaggerated?

Thanks in advance.

My article entitled 'Deep neural networks show an equivalent and often superior performance to dermatologists in onychomycosis diagnosis: Automatic construction of onychomycosis datasets by region-based convolutional deep neural network' is published on January 19, 2018.

We proposed the use of a region-based convolutional neural network (R-CNN) approach to created datasets of standardized nail images. It has been used to generate training datasets of approx. 50,000 images, which were then be able to fine-tune the ResNet-152 and VGG-19 models. This automated R-CNN approach increased the accuracy of CNNs. We then performed the CNN training with the datasets labeled by three dermatologists. In diagnosing onychomycosis, the CNNs trained with these 50,000 images demonstrate a better diagnostic accuracy than all dermatologists that participated to this study.

So far, AI's performance has been comparable to specialists in the medical field, and this is the first study showing that AI has overwhelmed the experts, as far as I know.

Article (PLOS One): http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0191493

Web DEMO : http://nail.medicalphoto.org

DEMO Screenshot : https://i.imgur.com/tAiQ0zI.jpg

Hey all. This sub looks pretty dead so I wanted to make a post for anyone who randomly comes here. I created the sub /r/onychomycosis as a place for people to share their experience with onychomycosis and what treatments did/didn't work. I currently have this fungus on all 10 of my toes so I understand how frustrating it is. Hope to see you there!

19

Male

5’9”

73kg

Australian-Chinese

Duration: around 2.5 years

Location: right thumb fingernail

No relevant medical issues/medications

I have been living with a fungal nail infection on my right thumb since mid-2016 (I think it arose when I was in hospital for intestinal surgery) and have tried most of the lacquers out there as well as laser treatment but nothing has improved the condition. Not yellow or anything just very thickened nail with white discolouration and grows very distortedly. My doctor has said the best thing to do would be to go on the oral medication (Lamisil) for 3 months, but after researching online and reading other people’s experiences, as well as getting advice from other professionals, I’m a bit hesitant as it seems like it’s a pretty shitty medication with not that high success rates. I just don’t understand why there are so many common side effects (headaches, upset stomach, liver damage, loss of taste/smell) for a nail medication. Are there any other options to this drug? Is surgical nail removal a popular treatment option?

Thanks in advance and have a nice day.

Hello, My toenail is getting completely white. No pain, no difficulty to walk or anything. Only one nail (middle one left foot) is affected, no others. I suppose this is a white superficial onychomycosis.

Is it necessary to visit or doctor? I'd rather not as it is expensive here.

Im a 25yo male. Had a bad brown fungus when I was a kid, the nail kinda fell down and a brand new clean one grew again.

Thanks!!

Has anyone successfully treated toenail fungus and actually gotten rid of it? What are the best things to use. At one time I had been using something that I cannot remember and it essentially caused my nail to fall off and grow back clean. I wouldn't mind finding that again, but I haven't been successful. Any other treatments that anyone suggests?

Hi all. I have seen an abundance of anecdotal reports of onychomycosis (toenail fungus) resolving or improving after following the ketogenic diet for several months. One should rightly be sceptical of anecdotal reports, but when the same effect is reproduced over and over again, you begin to suspect something is going on.

To me, it seems plausible that keto can improve onychomycosis. Fungus, to my knowledge, has a glucose metabolism -- it feeds off it. There might also be a beneficial immune-system effect: you're not bombing your system with inflammatory foods, so the immune system can go and take care of what is needed.

Do you think these mechanisms make sense? If not, why? And can you think of any others?

Or do you think the benefits of keto on onychomycosis and fungal infections generally (like athlete's foot) are exaggerated?

Thanks in advance.