Galanin neurons "By tracing the long axon fibers of this pool of neurons they found that they extend out from neurons in the hub region of the hypothalamus, the team closely investigated the function and anatomy of four of the 20 pools they had found. One set of axons projected to the periacqueductal gray in the midbrain, an area involved in motor behaviors. Manipulating that pool of neurons affected grooming behavior, although not the parents’ retrieval of pups. A pool in the ventral tegmental area (VTA), a reward-related region, controlled the motivation to engage in parenting tasks. When the VTA neurons were stimulated, both male and female mice worked harder to cross barriers placed between them and their pups. A third projection to the medial amygdala (MeA), a locus for emotion, inhibited competing social interactions with other adults such as male aggression against other males. The fourth projection led to the paraventricular hypothalamic nucleus, a key area for neuroendocrine control. This area modulated parenting-related hormones such as oxytocin, vasopressin and corticotropin-releasing hormone."
Other researchers have also performed blood transfusions between pregnant dams and virgin mice. The transfused virgin mice stopped their avoidance of mouse pups and began grooming behaviors.
Others have found that virgin female rats avoid or attack pups, but postpartum dams will press a lever more than 100 times per hour to have a pup delivered into their nest box with each press.
It is interesting to think where this discovery might be therapeutically applicable?
[https://www.nature.com/articles/s41586-018-0027-0.epdf?sharing_token=C1yuxHNnQora3ZlL2E89ONRgN0jAjWel9jnR3ZoTv0OCwg_t4gDmPeD0aWQSJwh3bV3ab-DAhVHmBkuuQ7jAMO5P99cB4XrK9vRWHoFZdXh5eHyfRBraxWOvUkj6RqqAygGk4jvv1-0kYXY2bw9Vffx4UM2Ln2X0sCfRFTuaso5N1SzXmSLzcvOuOKQa5fhK6WDAKsUyaG8w5ghLpRs_YSdzJGQGCHDqIwZLxwKnyWNnMXasK66xdE4q7O2DHx_PRvEw4pSp4YYe0DkRZaE3KcgsSD0Pm1H0wABDTEl0-IwBnTBDD222lTz8NmGw2sqK6TIDDTzFWxEZiDD_oLsB0g%3D%3D&tracking_referrer=www.scientificamerican.com](https://www.nature.com/articles/s41586-018-0027-0.epdf?sharing_token=C1yuxHNnQora3ZlL2E89ONRgN0jAjWel9jnR3ZoTv0OCwg_t4gDmPeD0aWQSJwh3bV3ab-DAhVHmBkuuQ7jAMO5P99cB4XrK9vRWHoFZdXh5eHyfRBraxWOvUkj6RqqAygGk4jvv1-0kYXY2bw9Vffx4UM2Ln2X0sCfRFTuaso5N1SzXmSLzcvOuOKQa5fhK6WDAKsUyaG8w5ghLpRs_YSdzJGQGCHDqIwZLxwKnyWNnMXasK66xdE4q7O2DHx_PRvEw4pSp4YYe0DkRZaE3KcgsSD0Pm1H0wABDTEl0-IwBnTBDD222lTz8NmGw2sqK6TIDDTzFWxEZiDD_oLsB0g%3D%3D&trackin
... keep reading on reddit ➡I am unable to find any comprehensive list of genes involved in epigenetics in mice. There are plenty of databases out there, but they all seem to only provide sequencing data in epigenetic studies. I figured a list would exist somewhere on Ensembl or NCBI, but I can't find it.
I'm looking for a list like this, but for mice.
https://epifactors.autosome.ru/genes
Thanks
Hi I've been visiting this r/Philippines for about 1 or 2 years now and I've seen lots of very knowledgable people here so I was wondering if you guys could help me in my problem I've been searching the internet for places to buy them but I just can't seem to find a authentic seller of mice for a legit experimentation....
Thanks In advance
So there I was, slumped back in my computer desk's chair, working on a terribly boring essay I'd been chipping away at all day. The room was silent, save the soft crunching of salty pretzels between my teeth. After one particularly large gulp, everything became still. I was home alone and, quite foolishly, believed that there were no other living things in my midst.
I was wrong. From a nearby wall I began to hear high pitched screeching noises, as if something were trying to communicate with me from the beyond. I froze in my chair as the hairs on my arms and the back of my neck began to rise one by one. And all of a sudden, a dark figure emerged from underneath the dining room table, not far off from where the initial screeching had come from. It lumbered towards me, each rapid step echoing the thuds from my accelerating heartbeat. As I prayed for forgiveness to my sweet Lord Jesus, I prepared to begin my journey into the afterlife. Then, without warning, the mouse darted in the other direction and returned to it's place of residence.
