I did some advanced lipid profile and below are the results, dangerous?
M/32
Fasted 12 hours
Eating Keto 5-6 months now
Eating Keto to lower blood sugar
Weight 170 - 6 pack abs, 12-13% body fat
Lost 15lbs, although not the intended purpose over course of Keto, I dropped from 182 to 164-5, than stabilized at 170-172.
LDL PARTICLE NUMBER. 1768 nmol/L
LDL SMALL. 201 nmol/L
LDL MEDIUM. 309 nmol/L
HDL LARGE. 8655 nmol/L
LDL PATTERN. A Pattern
LDL PEAK SIZE 224.8 Angstrom
APOLIPOPROTEIN B
112 mg/dL
LIPOPROTEIN (a)
10 nmol/L
HS CRP
<0.3 mg/L
LP PLA2 ACTIVITY
155 nmol/min/mL
I had recently lost a friend aged 25 due to an heart attack, which is really uncommon. This prompted me to get a Lipid Profile assessment for myself to and my results were also bad "~300".
Lipid Profile Assessment is basically letting you know amount of Low Density Cholesterol(LDL), High Density Cholesterol(HDL), It's ratio LDL:HDL and Triglyceride levels in your blood stream.
I had contacted my doctor due to my high levels and now I'm going to strictly monitor it. As per my knowledge I see many people going down before age of 50 due to heart related ailment, this is caused due to bad lifestyle habits and genetic history and this is very common in people of South East Asian decent.
Usually, people don't get lipid profile checked as they feel they are fit enough or they relate heart ailments to obese people. But please note this will be an epidemic of it's own sort for our generation (people born after 1990) we we turn 40+.
Lipid profile is very cheap these days it cost around Rs.900 where I live, and can be done every six months or on yearly basis.
Effect of a dietary intervention including minimal and unprocessed foods, high in natural saturated fats, on the lipid profile of children, pooled evidence from randomized controlled trials and a cohort study
Rosanne Barbra Hendriksen, Ellen José van der Gaag
Abstract Aim
To study the possible effects of a dietary intervention with minimal and unprocessed foods, high in natural saturated fats on the lipid profile and body mass index of children.
Method
This study combines three intervention studies; one non-randomized retrospective cohort study and two randomized controlled trials, to a pooled analysis. The intervention group received a dietary intervention of minimal and unprocessed foods for three to six months, consisting of five times per week green vegetables, three times per week beef, daily 200–300 mL whole cow’s milk (3.4% fat) and whole dairy butter (80% fat) on each slice of bread. The control group continued their usual dietary habits. Raw data of the three intervention studies where combined into one single dataset for data analysis, using mixed effects analysis of covariance to test the effects of the dietary advice on the main study outcomes, which are measurements of the lipid profile.
Results
In total, 267 children aged 1 to 16 years were followed. 135 children were included in the intervention group and 139 children in the control group. Characteristics (age, gender and follow-up period) were equally distributed between the groups at baseline. In the intervention group HDL-cholesterol increased significantly from 1.22 mmol/L, 95% confidence interval (CI) 1.14–1.32 to 1.42 mmol/L 95% CI 1.30–1.65 (p = 0.007). The increase over time in HDL cholesterol in the intervention group was significantly different compared to the increase in the control group (from 1.26 mmol/L, 95% CI 1.19–1.35, to 1.30 mmol/L, 95% CI 1.26–1.37) (p = 0.04). Due to the increased HDL concentration in the intervention group, the total cholesterol/HDL cholesterol ratio decreased significantly from 3.70 mmol/L, 95% CI 3.38–3.87, to 3.25 mmol/L, 95% CI 2.96–3.31 (p = 0.05).
Conclusion
Consumption of minimal and unprocessed foods (high in natural saturated fats) has favourable effects on HDL cholesterol in children. Therefore, this dietary advice can safely be recommended to children.
Citation: Hendriksen RB, van der Gaag EJ (2022) Effect of a dietary intervention including minimal and unprocessed foods, high in natural saturated fats, on the lipid profile of child
... keep reading on reddit ➡I fasted 48 hours before getting my cholesterol test as I did not realise it can affect the numbers. Lesson learnt! My doctor was concerned about the results and gave me a call. Here are the numbers
cholesterol 7.7 mmo/L - 298.4 mg/dl
HDL 1.3 mmo/L - 50.27 mg/dl
LDL 5.5 mmo/L - 212.7 mg/dl
Trig 2.0 mmo/L - 177.15 mg/dl
Cholesterol/HDL R 5.94
Triglyceride/HDL R 3.524
LDL/HDL R 4.23
I'd like to know - Are all these results worthless because of the fasting? How does fasting effects the results specifically - Is it just the LDL? Thanks.
M48, 170 lbs, 5ft 9 in
Lab Result from June 2021 (shocking):
Total: 371, HDL: 49, Triglycerides: 192, LDL: 284, Non-HDL: 322, VLDL: 38, HDL % of TOT: 13
Lab Result from September 2021:
Total: 142, HDL: 47, Triglycerides: 67, LDL: 83, NON-HDL: 96, VLDL: 14, HDL % of TOT: 33%
What changed:
- Diet: cut off whole milk, eggs, carbs (bagels, pasta etc), meat, alcohol
- Oats, non-fat milk / yogurt, whole grain, chia seeds, flax seed, chicken, salmon, turkey, salad, vegetables
- Exercise didn’t change. I have been training for marathon race before and after but the intensity of workout increased (ran 900 miles for the year).
- Started taking medication: statin and zetia.
- Started reading about good diet, exercise etc from this subredit and other resources — thanks a lot; it was really helpful.
Your thoughts on the results are welcome. Thanks.
https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC8408311/#
Search 'OP 19 Diet and nutrition' to find the following:
109
Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes
M.N. Thomsen1, M.J. Skytte1, A. Samkani1, A. Astrup2, J. Frystyk3, E. Chabanova4, B. Hartmann5, J.J. Holst5, T.M. Larsen2, S. Madsbad6, F. Magkos2, H.S. Thomsen4, R.L. Walzem7, T. Krarup1,2, S.B. Haugaard1;
1Department of Endocrinology, Copenhagen University Hospital Bispebjerg, Copenhagen, Denmark, 2Department of Nutrition, Exercise and Sports, University of Copenhagen, Copenhagen, Denmark, 3Department of Endocrinology, Odense University Hospital, Odense, Denmark, 4Department of Radiology, Copenhagen University Hospital Herlev, Copenhagen, Denmark, 5Department of Biomedical Sciences and NNF Center for Basic Metabolic Research, University of Copenhagen, Copenhagen, Denmark, 6Department of Endocrinology, Copenhagen University Hospital Hvidovre, Copenhagen, Denmark, 7Graduate Faculty of Nutrition, Texas A&M University, College Station, USA.
Background and aims: Elevated triglyceride-rich lipoproteins (TRL), excess small dense LDL particles (LDL5) and decreased HDL2/HDL3 ratio promote atherogenesis in type 2 diabetes (T2D). Carbohydrate restriction reduced intrahepatic triglyceride (IHTG) content beyond the positive effect of weight loss in a group of T2D patients, the present study sought to determine whether parallel improvements in lipoprotein density profiles occurred in these same patients.
Materials and methods: Seventy-two adult T2D patients with a mean±SD BMI of 33±5 kg/m2 were randomised 1:1 to 6 weeks of fully-provided hypocaloric dietary treatment aimed at ~6% weight loss, either with a carbohydrate-reduced high-protein (CRHP, C30E%/P30E%/F40E%) diet or a conventional diabetes (CD, C50E%/P17E%/F33E%) diet. Density profiles of lipoproteins were determined by ultracentrifugation of fluorescently labelled plasma. Magnetic resonance spectroscopy was used to assess IHTG. Treatment effects were evaluated using a constrained linear mixed model with inherent baseline adjustment.
Results: Body weight decreased by 5.8 kg (~6%) in both groups. Compared with the CD diet, the CRHP diet reduced TRL (mean [95% CI]) by -16 [-30;1]% (p=0.07) and LDL5 by -13 [-22;-3]% (p=0.01), and increased HDL2/HDL3 by 11 [1;
... keep reading on reddit ➡Hello there, I am 53, white male, BMI 23, moderately active, BP 120/83, generally eat whole and minimally processed foods, and I have high LDL and a coronary calcium scan score of 41. I had an advanced lipid test done to try to understand better what's going on.
Total: 242, HDL: 69, Triglycerides: 44, LDL: 160 (calculated by Martin-Hopkins), CHOL/HDLC: 3.5, Non HDl: 173, LDL particle number: 1497, LDL small: 189, LDL medium: 235, HDL large: 7480, LDL pattern: A, LDL peak size: 229.9, Apo B: 107, Lipoprotein (A): 16
From what I have read, aside from the LDL-related numbers, those are really good numbers, for instance, the CHOL/HLDC ratio and the fact that TG is also usually high if LDL is high. But would your response be, "Sure, we see this all time; it's not that surprising and you just need to eat better, exercise more, and consider taking a statin" or would your response be more like, "Yeah, that's weird. It might not be as simple as lifestyle. Look for familial hypercholesterolemia, insulin resistance, hypothyroidism (my TSH is still in the window for normal but above the middle) (or whatever else) or be careful with statins since they also lower TG, etc."
Given my CAC score, I am actually inclined to take a statin and am motivated to eat better and exercise more, it's not that I am scraping for reasons not too. Just curious about the range of possible explanations of my panel. My doc is pretty focused on the the LDL and just treating that.
Also, I thought a large number of small LDL particles was called Pattern B, but I have A. Can someone explain that? Thanks
Clinical Trial Endocr Metab Immune Disord Drug Targets
. 2021 Jan 4. doi: 10.2174/1871530321666210104145231. Online ahead of print.
Curcumin Nanomicelle Improves Lipid Profile, Stress Oxidative Factors and Inflammatory Markers in Patients Undergoing Coronary Elective Angioplasty; A Randomized Clinical Trial
Bijan Helli 1, Hadis Gerami 2, Maria Kavianpour 3, Habib Heybar 4, Seyed Kianoosh Hosseini 5, Hossein Khadem Haghighian 6Affiliations expand
- PMID: 33397249
- DOI: 10.2174/1871530321666210104145231
