Today is Esther Lederberg's birthday! celebrate the woman who discovered the Lambda phage! microbigals.com/post/invi…
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πŸ‘€︎ u/mocrobigal-01
πŸ“…︎ Dec 18 2020
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I made a fun holo virus vinyl and some model organism stickers including our fav E. coli, S. cerevisiae and Lambda phage πŸ˜† reddit.com/gallery/j1lofg
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πŸ‘€︎ u/notawizscientist
πŸ“…︎ Sep 28 2020
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Today is Esther Lederberg's birthday! celebrate the woman who discovered the Lambda phage! microbigals.com/post/invi…
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πŸ‘€︎ u/mocrobigal-01
πŸ“…︎ Dec 18 2020
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Today is Esther Lederberg's birthday! celebrate the woman who discovered the Lambda phage! microbigals.com/post/invi…
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πŸ‘€︎ u/mocrobigal-01
πŸ“…︎ Dec 18 2020
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Today is Esther Lederberg's birthday! celebrate the woman who discovered the Lambda phage! microbigals.com/post/invi…
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πŸ‘€︎ u/mocrobigal-01
πŸ“…︎ Dec 18 2020
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Novel "Irreducible" Functionality in Lambda Phage WITHOUT Loss of Original Function

Lenski's having a back-and-forth with Behe about the latter's new cash cow, which I personally think is a waste of time since Behe has never seemed interested in anything like listening to critics...or learning...or not repeating the same tired crap virtually verbatim for coming up on three decades, but I digress.

Anyway, Lenski explains an experiment on a bacteriophage (Lambda phage) that demonstrates a clearcut case of 1) an "irreducible" biochemical trait evolving, and 2) a novel function evolving without the loss of the original function.

My favorite example of such an evolutionary event is the evolution of tetherin antagonism in HIV-1 group M Vpu, but this will be number two on my list going forward.

 

Here's Lenski's explanation, which I'll summarize.

The short (and somewhat simplified) version is that Lambda uses a specific protein on the surface of it's host to inject its DNA, and it's never, in decades and decades of watching it evolve in the lab, evolved to use a different protein.

But this experiment (pdf) resulted in a strain that uses a different protein to inject its DNA. Once they isolated that strain, they replicated the conditions and found the same trait over and over. In every case, four mutations were required to use the alternate receptor (two of which were always the same, and two of which could vary slightly). Anything less and the trait did not appear. They actually generated triple mutants to check that all four mutations were needed and showed that three of the four were insufficient.

By Behe's own definition, this is an irreducible trait. But the researchers watched it evolve, over and over, 25 times in total, always requiring four mutations.

That is a direct refutation of Behe's original creationist argument, as articulated in "Darwin's Black Box". The next finding directly contradicts his argument in "Darwin Devolves".

 

This second finding is that these strains, exhibiting a novel trait, retained the ability to use the original receptor. In fact, some of the mutations required for the new function also improved the old function. This is a direct refutation of Behe's newish (ish because he's been making this argument for as long as I can r

... keep reading on reddit ➑

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πŸ‘€︎ u/DarwinZDF42
πŸ“…︎ Mar 12 2019
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I've been practicing 3D modeling for a few months and have always admired viral structures. Here's a simple Lambda Phage
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πŸ‘€︎ u/cozart_3d
πŸ“…︎ May 09 2019
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Lambda Phage, simple 3D model
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πŸ‘€︎ u/cozart_3d
πŸ“…︎ May 09 2019
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Lambda phage: a virus that eats E. coli en.wikipedia.org/wiki/Lam…
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πŸ‘€︎ u/unquietwiki
πŸ“…︎ Apr 16 2018
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What do you call a man with no arms or legs in a hole?

Phil

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πŸ‘€︎ u/Rumblebully
πŸ“…︎ Jun 30 2021
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Did you know Bruce Lee has a faster older brother?

Sudden Lee

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πŸ“…︎ Jul 02 2021
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DAD JOKES ARE NOT DIRTY.

Go post NSFW jokes somewhere else. If I can't tell my kids this joke, then it is not a DAD JOKE.

If you feel it's appropriate to share NSFW jokes with your kids, that's on you. But a real, true dad joke should work for anyone's kid.

Mods... If you exist... Please, stop this madness. Rule #6 should simply not allow NSFW or (wtf) NSFL tags. Also, remember that MINORS browse this subreddit too? Why put that in rule #6, then allow NSFW???

Please consider changing rule #6. I love this sub, but the recent influx of NSFW tagged posts that get all the upvotes, just seem wrong when there are good solid DAD jokes being overlooked because of them.

Thank you,

A Dad.

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πŸ‘€︎ u/Von_Bostaph
πŸ“…︎ Jun 18 2021
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I've asked so many people what LGBTQ stands for

So far nobody has given me a straight answer

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πŸ“…︎ Jul 04 2021
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Pulled a Dad Joke on a Nurse

I am currently in the hospital. I had a back operation yesterday. The surgical nurse came in my room and started asking questions about my back. She asked me if I had any falls during the last year. I responded just one. It was after summer.

She laughed and said in 20 years of doing this she never was told that joke.

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πŸ‘€︎ u/rei_920
πŸ“…︎ Jul 07 2021
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Anyone who can spell the word drawer backwards...

..... Will get a reward.

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πŸ‘€︎ u/VERBERD
πŸ“…︎ Jul 04 2021
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I'd ruther not say
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πŸ‘€︎ u/Un_FaZed211
πŸ“…︎ Jul 01 2021
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Why are elevator jokes so good

Because they work on many levels

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πŸ‘€︎ u/The_Fox1984
πŸ“…︎ Jul 05 2021
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Rational
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πŸ‘€︎ u/mainhoonmadrasi
πŸ“…︎ Jun 30 2021
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My wife blocked me on Facebook because I post too many bird puns.

Well, toucan play at that game.

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πŸ‘€︎ u/Zayan-ali
πŸ“…︎ Jun 30 2021
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Argon enters a bar, the bartender says β€œWe don’t serve noble gases here.”

Argon does not react.

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πŸ‘€︎ u/Dick_Squeakly
πŸ“…︎ Jul 06 2021
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If Apple made a car what would it be missing?

Windows

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πŸ‘€︎ u/Moplex1234
πŸ“…︎ Jul 02 2021
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There are only two white people in the movie Black Panther

Martin Freeman, and Andy Serkis.

They also play roles in Lord of the Rings.

I guess that makes them the Tolkien white guys.

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πŸ‘€︎ u/jzagri
πŸ“…︎ Jun 24 2021
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Interviewer : why should we hire you as a waiter?

Me : For starters, I bring a lot to the table

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πŸ‘€︎ u/Motor_Fox_9541
πŸ“…︎ Jul 08 2021
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My 3 yr old daughter made her first pun today and I almost cried. She was eating an apple and I asked her if she liked apples.

She said apple-lutely

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πŸ“…︎ Jun 29 2021
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He needs grounded
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πŸ‘€︎ u/AthanasiaStygian
πŸ“…︎ Jul 06 2021
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"ground" the kid
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πŸ‘€︎ u/freakynit
πŸ“…︎ Jul 03 2021
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MMM, burgers
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πŸ‘€︎ u/mkxviii
πŸ“…︎ Jul 08 2021
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What did the left eye say to the right eye when they got married?

'Eye-do'

This is my first post pls don't kill me lol.

The people in the comment section is why I love this subreddit!!

Cred once again my sis wants credit lol

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πŸ‘€︎ u/tieyz
πŸ“…︎ Jun 27 2021
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Well there goes his reproductive fitness...
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πŸ‘€︎ u/annnnnnnnie
πŸ“…︎ Jul 05 2021
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Proud dad moment.

Keep in mind, my son is 4 years old, so everything is an original to him.

I had to work late into the evening yesterday, and he was just going to bed when I got home. I had left home for the office nearly 14 hours prior, had a long day, lots of meetings, traffic, etc.

When I walked through the door, I was exhausted, run down, and starving. My wife hugged me and asked how my day was, and I replied, "Done. It was a good day, but has got me exhausted. I just want to grab a bite and go to bed. I'm hungry."

From my son's bedroom, I hear him shout, "Hi Hungry! Nice to meet you!"

Not only did it make me laugh, but I completely forgot about how hungry and tired I was. I went to his bedroom, and we laughed together about it. It was exactly what I needed.

Edit: Thanks for all the awards, kind strangers! I'll let my son know y'all enjoyed his joke too!

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πŸ‘€︎ u/LaBarbaGuapa
πŸ“…︎ Jul 01 2021
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What was a very common name in the middle ages?

I heard parents named their children lance a lot.

First post please don't kill me

Edit: i went to sleep and now my inbox is dead, thank you kind strangers for the awards!

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πŸ“…︎ Jun 24 2021
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Apologies if it's a bit corn-y
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πŸ‘€︎ u/mediashiznaks
πŸ“…︎ Jun 26 2021
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Gottemm
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πŸ‘€︎ u/Un_FaZed211
πŸ“…︎ Jun 29 2021
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Why did the toilet paper roll down the hill?

To get to the... Bottom...

(as told by my 5yo son, I'm so proud)

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πŸ‘€︎ u/wotmate
πŸ“…︎ Jul 05 2021
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so many choices
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πŸ‘€︎ u/SailorNebula
πŸ“…︎ Jun 07 2021
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What pan is the best to make sushi in?

Japan.

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πŸ‘€︎ u/Most-Stomach4240
πŸ“…︎ Jul 01 2021
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Well that didn't cross my mind
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πŸ‘€︎ u/JasonPetreasCoach
πŸ“…︎ Jun 11 2021
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He knows too much
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πŸ‘€︎ u/Potato_salad123
πŸ“…︎ Jun 24 2021
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I said to my wife, "I need to call the doctor today." Concerned, she asked, "Which doctor?"

"No, the regular kind!" I laughed.

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πŸ‘€︎ u/808gecko808
πŸ“…︎ Jul 03 2021
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where do pirates get their hooks?

second hand stores!

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πŸ‘€︎ u/bigus-_-dickus
πŸ“…︎ Jun 25 2021
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I've just deleted all the German names off my pre owned iPhone..

it's Hans free now..

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πŸ‘€︎ u/HugoZHackenbush2
πŸ“…︎ Jun 28 2021
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Charjar Binks
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πŸ‘€︎ u/MrCloud-YT
πŸ“…︎ Jul 04 2021
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I've spent all morning trying to think of a quality pun, just to come up with THIS otter rubbish.
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πŸ‘€︎ u/awesome_smokey
πŸ“…︎ Jun 28 2021
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3.14159265387279 snek
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πŸ“…︎ Jun 20 2021
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My 6 year old wanted me to share his joke with you all. What is a horses favorite store?

Old Neeeeiiiiighvy

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πŸ‘€︎ u/WantedDadorAlive
πŸ“…︎ Jun 28 2021
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Did you know 10+10 and 11+11 are the same?

10+10 is twenty and 11+11 is twenty too

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πŸ“…︎ Jun 27 2021
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Rock bottom
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πŸ‘€︎ u/Theo19555
πŸ“…︎ Jun 23 2021
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How much does it cost for a pirate to get his ears pierced?

A buck-an-ear!

I Thank ye kind Matey for the booty! I be truly overwhelmed! Thank you!

Holy cow! Thank you everyone for the upvotes and awards! I wasn’t expecting this!

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πŸ‘€︎ u/motherduck5
πŸ“…︎ Jun 25 2021
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