Hyoscyamine Puns

This dry mouth is no joke ... and its not touching the pain.

I've tried Bentyl, but I don't like the way it makes me feel. Kind of emotionless and out of it. Is Levsin better?

New to RC’s and a good homie who put on saw that this was the medication I was on. Ive tried acid and dmt both once and wondering if this medication has any psycho active effects or if it’s bad to mix with these chems. I had a pretty intense trip off of 100ug of LSD + 50ug of ALD52 the other day. Told me i had a hard chem to come across and in high dosages you could see shadow figures. I don’t doubt him, but what’s your input on this medication. I take this because I box and get bad stomach cramps from jump roping or eating before exercising etc.

So I'm still over here dealing with what they think is post-antibiotic IBS.

Most mornings I have a formed stool, but it's still very small caliber and it's soft/fluffy, disintegrates to nothing as soon as the flush starts. Sometimes it's more loose than that, like true diarrhea, but only intermittently.

Saw a new GI today who prescribed me hyoscyamine and suggested adding psyllium (1 T/day).

My concerns about the hyoscyamine are that it looks like it can cause constipation (DO NOT WANT), it primarily helps with pain (which I do not have much of) and it's got some potentially unpleasant side effects (dry mouth--which I already have from another medication, urinary retention, bloating, and tiredness).

I guess I'm going to try it, but I'm not sure this seems like the right med for me? Open to any thoughts/experiences with this med. Thanks everyone.

Has anyone with IBS-C had success with Hyoscyamine?

If curious, my background:

I have IBS-C and have been struggling with this for a decade now. I have a great diet and health regime but my body refuses to have an urge to go. I have been using two scoops of Miralax every night for the past couple of years and it really helps. Although it works for me, I don't want to only rely on Miralax for the rest of my life. So hey why not try another drug to fix an issue!

Any feedback or comments would greatly be appreciated.

Am I the only person who pronounces this drug as if I'm speaking Parseltongue? Gotta have some fun in the pharmacy somewhere. :)

Hey y'all I was recently perscribed Hyoscyamine for my stomach issues and was wondering if it's safe to take with Miralax. I have IBS-C, but I get cramps on top of that. Has anyone else taken the two and how was it?

Edit: Hyoscyamine seems to upset my stomach further however, Miralax helps a lot

I (27M) have had acid reflux for years, and about two years ago I got my first bout of severe chest pains. Two ER visits, two rounds of ekg’s, two gallbladder tests (ultrasound and the other one), endoscopy, stress test/imaging on my heart and basically all my old GI doc said was I have esophageal spasms and acid reflux. Heart was ruled to be fine. Gallbladder and it’s functions fine. No damage or anything with the esophagus/stomach. I’ve been taking prescription PPI’s for probably 2 years now, over the counter before that, and for the past couple years mixing in Pepcid here and there when I feel my acid reflux flare up, and I have hyoscyamine for the chest pains. I don’t get chest pains super often, maybe once every 1-3 months but I do have discomfort fairly often and I use the hyoscyamine to try and keep it from turning into a full blown crippling chest pain attack. I moved to a new state but I was pretty much done with my last GI with no follow ups scheduled and just a prescription I can keep refilling.

I’m thinking about seeing another GI in my new state to get a second opinion because the last guy was an older gentleman and just didn’t see an issue with taking PPI’s forever, and after reading around it doesn’t seem like it’s the best option

For those who take hyoscyamine for spasms/chest pain, do they always work for you? Night before last I had a bout of really bad chest pains, and even though I stuck two of those pills under my tongue they didn’t do much, if anything. I swear they work sometimes but maybe I have to catch it early enough? I can usually feel some discomfort some time before I actually get those crippling pains, so I’ll usually take some preemptively to not have to live through any more pains than I have to. It seems like that works, mixed with trying to stay sitting up or standing and breathing.

Also, for those who get those chest pains, how do you deal with the anxiety? Even though I’m pretty active, supposedly have a clean bill of health on my heart, and from blood work I get done every year for insurance know that other than a slightly elevated bad cholesterol level and being slightly overweight I’m at a pretty good standing overall, I still get freaked out every time the chest pains hit. I can’t stand listening to medical stories or reading about people getting diagnosed with diseases or cancer or whatever because it makes me feel so uneasy and freaked out.

Kind of a rant, but just looking for some validation on how I feel a

I want to trip soon and am going to be taking a new antispasmatic medication to help me with my stomach issues. Just wondering if anyone knows if taking hyoscyamine and shrooms is a bad idea

Just wondering if you build a resistance/immunity to them the more that you introduce them to your body

Does alchemestry have Hyoscyamine or equivalent in? I really want a crasher sword in 1.12.2

The instructions say to take one tablet by mouth twice daily. do you guys think I should do that? or should I keep at one time I day. I am seeing some people say that they only take it when they are having a flair.

I can't find concrete information anywhere. I have some phenobarbital with L-Hyoscyamine tablets and i'm looking to do an extraction, I know Phenobarbital has very limited solubility in water, so i'm hoping L-Hyoscyamine is freely water soluble and it's as simple as that.

Does anyone know concrete information about the solubility of L-Hyoscyamine?

I am 30+ years old and have had serious IBS-D for what feels like my entire life, and it’s only gotten worse as I’ve gotten older. Blacking out, apparently turning blue (lol) at the worst of some of the episodes.

Every single time I’ve gone to my doctors, every single time I’ve wound up in the ER, every single time I’ve EVER looked for something to deal with this ungodly pain, I have never found or been given answers. Only “it’s just IBS, take some Imodium or pepto bismol & you’ll be fine!” 🤪 I did a telehealth appt Friday to get my regular anxiety meds renewed. This total stranger of a doctor asked me what felt like just a few extra questions outside of info related to the prescription renewal and if it’s been helping or not. And she up and suggested to me to “try this medication” when I had my next flare up and see if it helped. Hyoscyamine. Never heard of it but sure! Anything to make this be less like torture. The pharmacy attendant didn’t even know how to say the name.

So I took one a few hours ago, when I felt my stomach start that obnoxious cramping that always starts first. Teeny little thing that you let dissolve under your tongue. I think within maybe 30 minutes, MAX? It felt like those muscles relaxed almost completely. I can tell my stomach is still not happy, but that otherworldly pain is nearly nonexistent right now. It feels like just the tiniest wisp of a stomachache. I could run miles right now and my stomach wouldn’t feel like it was trying to murder me.

Where the heck has this medication been all my life, and why THE HELL have doctors over all these years not even mentioned it?!! ER doctors especially, what the ever loving F?! Is this medication super new? Because you can bet next time I go back to my regular doctor, I’ll be ranting and raving about hyoscyamine and telling them they need to start prescribing it if they don’t. I’m both so, so relieved and overjoyed that the pain during this flareup might as well be GONE, and absolutely, blindingly furious no one has EVER suggested or even thought to try prescribing it for me before.

My doctor just prescribed me hyoscyamine as well as Pepcid. Has anyone tried these? One or the other- or both, are causing me pretty bad constipation, as well as a LOT of bloating... I’ve taken miralax two nights in a row, and obviously that helped a lot and my doctor said to continue that but I’m still super bloated even after I go.. I’m considered underweight as well (genetics) so it’s very easy to see how bloated my stomach is. Anyone know anything or have a solution?

I was desperate to get high and did the tried and true rummaging through the house for pills .... "DPH nawww fuck that"....let me clarify I have been sober out of rehab for 2 months and fell off the wagon last night I found 40 .125 hyoscyamine dated 2010 and dumped them in my cheek ...(definitely the best tasting pills out there) and probably the most desperate relapse anyone's ever done...within 15 minutes I thought I was under my bed when I was on top of it I started getting super paranoid the mattress and box spring would fall under the frame and crush me so I lift up the covers and I'm on top of the bed.... completely surprised that it actually did something like that I went outside to go smoke a cigarette and about a hundred feet away I saw a crystal clear me looking right back at me then I started getting excited that it worked and walked on the edge of the lake I live by I decided to commandeer a kayak that someone left down on the edge of the lake and paddled out maybe a quarter mile I was so pumped I mean I was AMPED TF UP it felt like I railed 60mg Adderall then I would crash and lay back on the kayak for 30 minutes and then the rush would come back HARD... I can't explain it...it felt like nitrous almost but then it would crash down to almost a dxm-like feel...i hopped off the kayak a few times into the cold water because when I would come out of the water I would feel really warm ... This is where things started getting dangerous as if being in the water without a life jacket on a bliss delirium wasn't already stupid enough I thought man I want to see some fireworks went into my house and grabbed a few mortars that I saved from 4th of July and walked maybe a mile from my house on the edge of the lake lighting the tube in my hand and just pointing it in the air probably waking up everyone in the neighborhood I feel super bad about that btw... I just didn't care I was legitimately tweaking the fireworks would ring in my ear over and over like an echo and then I kayaked all the way to the cliffs where people jump on the lake "party-cove" I thought "man I'm going to throw a gainer off this ho" i got to the top of the cliffs after super long fucking paddle and thank God I thought to myself "fuck that I can't even see the water"...so I just sat there with my legs dangling on the cliff when I see my dog lolly walk up I asked her wtf are u doing dog and tried to pet her but she turned to dust and that freaked me TF out I don't really remember what happ

I used to take low-dose hydroxyzine and amitriptyline for symptoms, and it was very effective. I was mostly “in remission” for a long time, most of the time off all meds, but after a recent UTI I’ve been flared up. My new uro is very into pelvic floor dysfunction as a cause of IC. I’ve done physical therapy before for a hypertonic pelvic floor, but I didn’t really give it a fair shake. I’m starting physical therapy with a hospital-affiliated therapist soon, but the uro also gave me hyoscyamine to try for pain. My main symptom is urethral burning, and she thinks it’s nerve related, stemming from this constant pelvic floor over-engagement, I guess. Has anyone used it? I’m terrified of urinary retention because it happened to me once while I was trialing Zoloft, and I read that can be a side effect.

I have a flare up. I am moving tomorrow. It’s a very big day. I am so pissed off this is happening to me tonight. I took hyoscyamine 20 minutes ago- it was prescribed to me for IBS.

It doesn’t seem to be working. I am in terrible pain and keep running to the bathroom but nothing happens. Ugh. I’ve had this happen to me before or during stressful events in my life and I am so damn sick of it!!!

I’m probably gonna be up all night with this literal shit and I’ll be a mess tomorrow. :(

A few days ago i was messing around in a modpack i made and i remembered hyoscyamine crashes people, so i tried it out and sure enough it crashed my game, just this morning i tried it again out of boredom and it didn't crash me this time, and it hasn't since, so i was wondering if anyone knew why this is?

I was recently researching the bronchodilator properties of the alkaloids contained in Datura Stramonium. In the past cigarettes rolled with Datura where used in cases of asthma and bronchitis. Even in modern medicine atropine sulfate has been used as a bronchodilator and to dry up mucus in the upper respiratory tract. Well I got the bright(or crazy) idea to make a vegetable glycerin tincture using Datura Stramonium seeds. I finely ground up 60 Datura seeds. I then placed those seeds in 1ml of Pure USP vegetable glycerin. I am now steeping said seeds in the VG to create a crude tincture. I plan on straining and placing this tincture in a Sub OHM tank and testing out the effects. I understand the great toxicity of Datura as I have used it many times in the past. Not to trip out, but to clear out my nose or reduce eye redness. I’m aware of the varying alkaloid content and exercise great caution when using this powerful herb. My hope is to get a vapeable solution that contains Atropine, Scopolamine, and Hyoscyamine, but without enough to cause any deliriant effects. I am going to slowly test the waters and take a drag and wait around 30 minutes after each drag. I will know it is working when I feel dry mouth coming on and will be regularly checking my pupils for any dilation before and after each dose. As of now the VG has changed to a green color and smells very much like Datura Stramonium seeds. I plan on letting it steep for a few more days whilst periodically heating up the solution and mixing it a few times a day.

I am having excision surgery in January and my surgeon sent me to a GI specialist because she suspects she will find bowel involvement and wants me to have a relationship with a GI.

I met with the GI specialist on Friday and told him about the “butt lightning” I experience. He prescribed a medication called hyoscyamine (brand name is Levsin/SL) which is an antispasmodic. I let it dissolve under my tongue and in about 20 minutes it stops all the muscle spasms in my rectum. I got my period today and tried it out... IT WORKED. The doctor said it might make me a little drowsy but I didn’t notice any drowsiness. No other side effects that I’ve noticed either.

I still had a little bit of pain during my bowel movement but nothing like what I’m used to (normally I’m afraid I’ll pass out from pain on the toilet, and I can’t sit normally for HOURS after). I didn’t know this type of medication existed and I’m a little upset it took me 20 years of horrible period poops to find out. Posting here in case the info helps anyone else.

Hello everyone

After months of being on protonix I found myself still feeling awful stomach and back pain. I finally got fed up and found a new gastroenterologist (my last one was pretty awful.) I told the new gastro my entire year long battle. After many questions the gastro finally came to the conclusion that it wasn’t an ulcer and possibly not even gastritis but stomach spasms from pro longed stress. The gastro put me on hyoscyamine for 3 times a day ( 30 minutes before each meal) for a month and I have seen a vast improvement, the burning gnawing pain hasn’t occurred in 3 days. I have tested out trigger foods and caffeinated drinks and still have yet to feel pain. Has anybody been prescribed this?

i’ve suffered from attacks for the last three years. about a year ago i was diagnosed and put on the medication hyoscyamine. it helps with pain and i haven’t had an attack since i’ve started it, but the side effects are not great. it’s a sedative and i have to take it about four times a day. my memory has turned to shit and for months it was difficult for me to drive because it was so hard for me to focus. does anyone else take this and deal with the same stuff?

Been prescribed this as one of the tools to manage my IBS which is neither C nor D. I have the higher .375mg tablet vs the dissolving one. I have a great GI, but he basically told me that he didn’t know the best method for taking it. Like he says I have to experiment (before meal, after a meal, as soon as cramps come on, etc) Does anyone have some experience with this drug (either with the dissolving tablets or the pill) and can you share your method? I usually get a lot of cramps and bloating after eating which can lead to a flare up that lasts days. I have Librax too but he says try one medication at a time and not to mix these two. Not sure how well the Librax is working (or if I’m even taking that correctly!) so I’m giving the hyoscyamine a shot instead for a week or more. Thank you!

I just took about 4-5 hyoscyamine tabs 0.375mg I wanted to know if this was a good dose or not enough

I recently saw a GI doctor who thinks IBS is probably what is going on with me and he told me to take Align daily plus hyoscyamine when needed. Should I use it for a bad flare up? How have you used it?

Since I’m new to this, where do I go from here as far as treatment goes? My doctor didn’t talk to me about diet or possibly starting an antidepressant.

I’m new to the IBS-D game.

My doctor prescribed me Bentyl as needed and Wellbutrin xl daily about 1.5 weeks ago. I’ve seen major improvements so far - far less BM, no diarrhea, normal color and consistency. FINALLY!

Bentyl definitely worked but I could only take it at home due to drowsiness, foggy thinking and overall feeling strange. I e-mailed my doctor asking for an alternative and he gave me hyoscyamine (generic for levsin) 0.125 mg as needed.

Has anyone had a more positive experience with this drug over Bentyl?

Hey, I was just prescribed hyoscyamine as my only treatment for the pain I've been dealing with with Crohn's disease. Does anyone have any experience with this med before? Thank you!!

I was on the original levsinex time caps and they were a godsend for me. When they were discontinued, I tried levbid by ethex, which also worked very well. Since then, I've settled for lesser SL tablets that work to a degree, but they manufacturers keep discontinuing them (most recently Virtus). I'm now kinda screwed, having just tried Bentyl and not able to tolerate side effects. Anyone else have this issue of not tolerating the different generics of this medication? It's so frustrating because I know it works, but it feels like I'm back to the drawing board now. Any antispasmodics that aren't levsinex or peppermint caps (they never worked for me)?

My doc just put me on this - anyone have any experiences with this med?

I have Gerd and really bad muscle spasms in my throat and under jaw and an inflamed esophagus. I was given hyoscyamine for the bad spasms and they work great temporarily. I've already left a message for my dr but I'm wondering if anyone else experienced itching as a side effect? I've recently had to take it more often, every day due to a really bad flare up. I was switched to protonix two weeks ago and thought it was the new drug but just realized I had also increased this one too and it might be the actual culprit.

Hi hello IBS people. I have ibs-c, and my doc prescribed levsin to me a few months back. The prescription says to take every 6 hours daily, but my doc said take as needed 'when my stomach feels like it's spasming'. That isn't really a common side effect for my ibs, but my stomach still hurts almost constantly. Here are my questions: -Do you take this medicine? -Do you take it routinely or as needed? -How does it help you? -What are some negative effects of taking it?

Google has not been very helpful here really.

Thank you!!

So I have Hyoscyamine sulphate 0.125mg/ml , 15 ml bottle , what would be a safe dose for delirium. If I take 1.5 mg would that be ok ? It is similar to scopolamine found in Datura. Anyone has any experience with this substance ?

A few days ago i was messing around in a modpack i made and i remembered hyoscyamine crashes people, so i tried it out and sure enough it crashed my game, just this morning i tried it again out of boredom and it didn't crash me this time, and it hasn't since, so i was wondering if anyone knew why this is?