I talk about the benefits of plant-based diets, so sorry ethical vegoons, but if it makes you all feel better I'll put Dominion in the reference list for 500 upvotes ;)
For those of you fascinated by the epidemiology and origins of contagions, I recommend this NYTimes Opinion piece written by David Quammen. Quammen is an excellent writer/scientist. I first read his work a decade ago when he published Spillover. I strongly recommend this book. In fact, I’ve been recommending it to friends and family since I first read it and have done so dozens of times during the current pandemic. I am sure many in this community have read it. If you have you may agree with me that Spillover and Quammen’s other books represent a chicken or egg model. As in; Read it, becomes a biotech investor or became a biotech investor, read it. It an essential text for those who wish to know why.
On an Innovation Pharmaceuticals note; for those who might argue the COVID-19 opportunity is past (it isn’t), and IPIX has missed the bus (it hasn’t), there will be other buses. Brilacidin has pan-Corona potential. Modeled after nature’s Host Defense Proteins (HDPs), Brilacidin, destroys virus (and bacteria, and fungal pathogens), by rupturing their cell membrane. Brilacidin will play a vital role as humanities first line of defense, first-in-class cure for existing and novel (emerging), illnesses for decades to come, in the form of multiple indications. Know what you own. Know it potential value.
Zoonosis has been identified as the root source of the SARS-COV-2 virus. Whether the first “leap” occurred in the wild, a wet market or in a lab the resulting spillover has devastated the globe. West Nile Fever and Zika, two, traditionally subtropic, virus borne ailments have become common reoccurring illnesses in the US. The emergence of novel illnesses demands greater efforts to bring new antivirals to the fight.
Now a new threat. Antibiotic resistant bacteria, rarely seen in the US and until now not known to have an ecological niche in the US, appears to have gained a foothold. Multiple cases of Burkholderia pseudomallei caused infections have been diagnosed in the continental US. And unlike any know US case of the past, these new cases seem to have their origins, literally, in US soil.
The number of cases is very small. But, the indigenous origin is unsettling. Similar to the climate-driven expansion of West Nile and Zika the changing climate is creating a hospitable environment for novel pathogens. Pathogens that will test the capability of currently approved antivirals and antibiotics.
New therapeutics are desperately needed. Making the current research into Brilacidin, clinical trials and academic research, all the more valuable to humanity.
Two articles worth reading:
New, deadly bacteria may be lurking in US; CDC warns of three puzzling cases
Adaptation and Antibiotic Tolerance of Anaerobic Burkholderia pseudomallei
#Nostradamus Would be Jealous – Viral Zoonosis and the Origins of SARS-CoV-2 (COVID19)
So, first things first, this exists. The dankest of timelines indeed!!! More on tigers later (seriously).
Now that I’ve covered the basics in my last post, it is now time start to get at the questions that the modal mottleman may actually care about.
Today, I will continue my love affair with Whiteclaw and talk to you about zoonosis, which is defined as the process by which a virus moves from infecting one host organism to a different host organism and most frequently used in the context of a virus’s infection of human populations. We will first discuss zoonosis generally, examining common features of the process shared by all viruses. I will then discuss the zoonosis of coronaviruses specifically, looking at some general patterns and discussing some specifics in regards to the SARS-CoV-1 epidemic which occurred in 2002. Then we will get to the good part, as I will go over precisely how the scientific community believes we got into the mess we refer to as COVID19. Note, I am going to focus specifically on what we know, today in early May 2020, from the standpoint of Virology. I will be honest about what we know, what we don’t know, and we scientists will be looking into further regarding this outbreak. I know you will have a lot of questions regarding this, and I will do my best to answer what I can.
##I. An Introduction to Viral Zoonosis – Death, Host Mayhem, and Molecular Madness
Prior to COVID19, a common misconception I often found when talking to the laymen was that viruses limit themselves to a single host: that there are “animal viruses” and “people viruses”. While there is a sliver of truth to this sentiment^(i), the real world is far from that simple. Why generally a rare event in the statistical sense, zoonosis is the process whereby a virus moves from circulating in one species to infecting another species, often termed “host range expansion” in scientific speak. The factors regulating this process, that is determining which viruses can begin to infect which new hosts, are complex and still being discovered. However, in general I am able to break things down into 2 broad categories: Molecular Barriers and *Host Contact Barriers
... keep reading on reddit ➡Hey there!
I'm working on a paper on One Health that tries to analyze how the human health has imrpoved drasticallt in the mediterranean region after most of its countries (in the northern shore of the med) joined the EU.
I'm looking for sources and studies of the evolution of prevalence of different zoonotic diseases but can't seem to find something accounting for the changes in legislation (and hence diminishment of prevalence) , does anyone here have a source or somewhere that they could point me to in relation to this?
I work at a Zoonosis Center, that in my country at least is part of the municipality, but I have some doubts about how exactly should I tag it. If I search for "municip", "town", "city", "public" none of the results seem to fit; we are definitely not a veterinary center, nor a hospital, sanctuary or refugee.
It doesn't help that English is not my native language so I may be missing the exact word hahaha.
Thanks in advance!
This is the best tl;dr I could make, original reduced by 66%. (I'm a bot)
> More than 3,000 people in northern China have been diagnosed with a bacterial infection after an outbreak caused by a leak at a biopharmaceutical company last year.
> Almost 22,000 people in the city of Lanzhou, capital of Gansu province, were tested and 3,245 came back positive for brucellosis, the National Health Commission of Lanzhou has said.
> In a statement, the NHC said brucellosis was detected in November 2019, after a leak "Caused by contaminated exhaust from a vaccine factory in Lanzhou, due to the use of expired disinfectant from late-July to mid-August last year".
> The factory's licence to produce the brucella vaccine was revoked and it shut down its production department.
> Sinovac, a Beijing-based biotech company, currently has its vaccine in stage 2 trials, with more than 1,000 volunteers participating.
> A Chinese health official this week said the country may have a vaccine ready for public use as early as November.
Summary Source | FAQ | Feedback | Top keywords: vaccine^#1 people^#2 Lanzhou^#3 More^#4 infection^#5
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hi guys,
I’m a biological sciences major with a concentration in microbiology. I’m really interested in going into zoonosis research but not sure how to go about it academically. I know I definitely am going to need graduate school but I don’t know which degree to go for - in between an MS in epidemiology, biochem or Marine-Estuarine-Environ Sciences.
Honestly afraid of going too niche with my qualifications because all I hear are the struggles of getting employed in general here and in r/biology.
If anyone could slap me with some advice, it would be very much appreciated!
Just curious in a speculative sense.
Suppose a highly contagious, airborne virus emerged worldwide that was transmissible between man and dog, perhaps even cats. One with a modest but considerably above trivial death rate. After a typically successful worldwide disbursement of a vaccine, how would such a disease then affect public health? I expect eradication would be off the table for some time. Surely we couldn't vaccinate entire populations of strays, or have mandatory checkups before taking your pet to the dog park. What sort of risks would be posed by having such a disease always moving throughout a reservoir that we are so close to? How would public health policy likely approach managing those risks? What would life be like under those policies?
Thanks for any responses.
