Quick animated loop of the winding filament model for a muscle sarcomere v.redd.it/1cmqbp0fxrs61
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πŸ‘€︎ u/clockworkshow
πŸ“…︎ Apr 12 2021
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Understand length tension relationship in skeletal muscle along with its physiological basis (Sarcomere level)
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πŸ‘€︎ u/Physiologyopen
πŸ“…︎ May 15 2021
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Quick SARCOMERE structure MNEMONIC

Composed of actin and myosin

BANDS acTHIN -thIn (I BAND) myHosin be thick (H zone) actin AND myosin (A band)

To remember the zones that shorten remember to always WAVE and say HI (H zone and I band, A is unchanged) then you say Z you later at the end of each sarcomere

Correct me if anything is incorrect please πŸ‘ŒπŸ»πŸ€ŸπŸ»

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πŸ‘€︎ u/EatyoVeggies123
πŸ“…︎ May 12 2021
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Be gone yoga ignoramuses... for I know the big SCIENCE words!!! (TFW your sarcomeres deserve better smh)
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πŸ‘€︎ u/patchclampgal
πŸ“…︎ Sep 21 2020
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How do two Sarcomeres next to each other contract at the same time?

Since two Sarcomeres located next to eachother share a Z-line that separates them, their respective Actin filament can't both glide and pull the Z-line towards their respective M-band? Wouldnt that just be a tug of war?

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πŸ‘€︎ u/AronwithoneA
πŸ“…︎ Sep 14 2020
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Calcium is necessary for cross-bridge cycling, and the removal of calcium when the motor neuron stops signaling is what triggers relaxation. But how do the sarcomeres get longer? What pulls them out to their former length?

What provides the physical force that causes the sarcomere to lengthen when the muscle relaxes?

I know about the myosin heads unbinding from the actin, but what's pulling the sarcomere back to its regular length? Is it the Z-disc?

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πŸ‘€︎ u/BeejBeachBall
πŸ“…︎ May 17 2020
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Length of sarcomere and strength of contraction

I am trying to understand the answer to the following question: (T/F): The shorter the sarcomere length, the stronger the contraction.

In my research I'm coming across what seems to be contradictory info on this. Khan Academy has a video explaining that as the length of the sarcomere increases, the tension it can produce increases (up to a certain point, before dropping off).

If this is true, then why does the sarcomere shorten in order to provide the force generated during a muscle contraction? Wouldn't it imply that your muscles are capable of providing greater force in their relaxed, longer state?

I must be missing something, please help.

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πŸ‘€︎ u/MandrewTheFirst
πŸ“…︎ Oct 25 2018
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Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy | Circulation ahajournals.org/doi/abs/1…
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πŸ‘€︎ u/Bam-Bams
πŸ“…︎ Jan 27 2020
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Sarcomere questions

I've looked everywhere, but I cannot seem to get a consensus on lengths of H band and I band during contraction and relaxation. Can someone help me with this?

What about the overlap between myosin and actin? Does that change with contraction and relaxation?

With higher preload, will this be considered relaxation or contraction for the muscle?

Thank you so much!

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πŸ‘€︎ u/orgotime
πŸ“…︎ Jun 14 2020
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A mechanical model of the half-sarcomere which includes the contribution of titin biorxiv.org/content/early…
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πŸ‘€︎ u/sburgess86
πŸ“…︎ Oct 04 2018
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Genetic Determination Of Allocation Of Sarcomeres Upon Anabolism

Assume that two individuals who possess an identical diet, sleep pattern, nutritional regiment, who have spent equal times training, and who train all parts of the body at the same frequency, same volume, and same intensity are all x weight at 5% bodyfat at some part in the year. Then assume that next year at the exact same point in the year, they both weigh x+2 lbs of pure, lean muscle at 5% bodyfat. (No change in bodyfat)

What determines what sarcomeres are molded where? Why/how will one individual's body for example use the two pounds of muscle that was created by generating it in the areas of say the shoulder and chest while the second individual might have that muscle tissue generated in the quadriceps?

Assuming you train all bodyparts with equal intensity, what determines what parts of the body you're "gifted" in? For example, having naturally easy to grow/large shoulders while another person might have naturally easy to grow hamstrings or lats?

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πŸ‘€︎ u/120KGHeavyBench
πŸ“…︎ Jul 28 2015
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Sarcomere Contraction (on neighboring Sarcromeres)

I'm trying to find a visual or book or something explains how Sarcomeres interact with their neighbors.

So I get that the Z-disk is pulled towards the M-Line (center), but yet neighboring Sarcomeres share Z-disks, so how would a shared Z-disk be pulled towards the center of two M-lines? Do certain Sarcomeres get a bigger calcium influx to allow for stronger contraction to outcompete its neighbor?

I just can't seem to find a decent explanation or animation that goes beyond a single Sarcomere, although I'm sure I could eventually find it. Maybe I'm just not using the right keywords.

I know the title is misspelled.

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πŸ‘€︎ u/Assassin5757
πŸ“…︎ Aug 21 2019
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What happens at a molecular level during an isometric contraction? If the sarcomere isn't shortening how is the ATP being used?
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πŸ‘€︎ u/ShokugekiNoKyojin
πŸ“…︎ Jul 02 2018
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Sarcomere-like electromagnetic actuator

How strong is that thing? I wanna use it for my exoskeleton. How much force it can produce?

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πŸ‘€︎ u/Kuben97
πŸ“…︎ Jun 02 2016
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The Popping Sarcomere Hypothesis - suggesting shifts in optimal muscle length are a result of sarcomere addition in muscle fibers aups.org.au/Proceedings/3…
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πŸ‘€︎ u/phrakture
πŸ“…︎ Jun 06 2013
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How do all of the sarcomeres of muscles line up?

Is there some mechanism by which all of the z discs and m lines and h zones line up in muscles? And is there a reason that they do?

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πŸ‘€︎ u/diabeticgiraffe
πŸ“…︎ Oct 09 2015
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Sarcomeres?

Between what two regions would contraction occur within a sarcomere? Would it be from Z-disk to Z-disk, because that's where the actin's are anchored? So it would like compress inwards?

Thanks!

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πŸ‘€︎ u/mc23123
πŸ“…︎ Feb 02 2016
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Sarcomere
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πŸ‘€︎ u/Pandasonic9
πŸ“…︎ May 25 2017
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