Okay so don't ask me how but could it be as we saw in Hawkeye Renin suit got out or was stolen, Electro some how managed to get the arc reactor form the Avengers compound. Bet he's from the same Universe.
πŸ‘︎ 14
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πŸ‘€︎ u/mememerizer
πŸ“…︎ Dec 02 2021
🚨︎ report
High Aldosterone/Renin Activity ratio

I’m 29 year old female. Over the last 6 months, I’ve had severe chest pain lasting for about 7 days. My doctor narrowed this down to high blood pressure causing my issues.

I’m in the process of being tested for secondary hypertension. I just received my blood work back and the Aldosterone/Renin Activity ratio was 64, where normal range was less than 25. My aldosterone level was 19.2 ng/dL and my renin was 0.3 ng/dL

My main question is if this is going to be enough information to diagnose secondary hypertension? Are these results conclusive or what more information would be required?

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/FantasticPear8
πŸ“…︎ Nov 22 2021
🚨︎ report
Step 1 q : What test measures renin expression? Western blot, northern blot, southern blot, RT- PCR?

Is it western blot?

πŸ‘︎ 5
πŸ’¬︎
πŸ‘€︎ u/Dedicateddarkhole
πŸ“…︎ Sep 25 2021
🚨︎ report
Obesogenic and Ketogenic Diets Distinctly Regulate the SARS-CoV-2 Entry Proteins ACE2 and TMPRSS2 and the Renin-Angiotensin System in Rat Lung and Heart Tissues. (Pub Date: 2021-09-25)

https://doi.org/10.3390/nu13103357

https://pubmed.ncbi.nlm.nih.gov/34684358

Abstract

BACKGROUND

Obesity increases the severity of SARS-CoV-2 outcomes. Thus, this study tested whether obesogenic and ketogenic diets distinctly affect SARS-CoV-2 entry proteins and the renin-angiotensin system (RAS) in rat pulmonary and cardiac tissues.

METHODS

Male Sprague-Dawley rats were fed either standard chow (SC), a high-fat sucrose-enriched diet (HFS), or a ketogenic diet (KD) for 16 weeks. Afterwards, levels of angiotensin converting enzyme 2 (ACE2), transmembrane protease serine 2 (TMPRSS2), RAS components, and inflammatory genes were measured in the lungs and hearts of these animals.

RESULTS

In the lungs, HFS elevated ACE2 and TMPRSS2 levels relative to SC diet, whereas the KD lowered the levels of these proteins and the gene expressions of toll-like receptor 4 and interleukin-6 receptor relative to HFS. The diets did not alter ACE2 and TMPRSS2 in the heart, although ACE2 was more abundant in heart than lung tissues.

CONCLUSION

Diet-induced obesity increased the levels of viral entry proteins in the lungs, providing a mechanism whereby SARS-CoV-2 infectivity can be enhanced in obese individuals. Conversely, by maintaining low levels of ACE2 and TMPRSS2 and by exerting an anti-inflammatory effect, the KD can potentially attenuate the severity of infection and migration of SARS-CoV-2 to other ACE2-expressing tissues.

------------------------------------------ Info ------------------------------------------

Open Access: True

Authors: Daniel Da Eira - Shailee Jani - Rolando B. Ceddia -

Additional links:

https://www.mdpi.com/2072-6643/13/10/3357/pdf

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8541329

πŸ‘︎ 43
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πŸ‘€︎ u/Ricosss
πŸ“…︎ Oct 25 2021
🚨︎ report
Hello, can I change all the premade cards with cloze format so that everything is {{c1::}} ? for example so that aliskiren and renin are both {{c1::}}πŸ₯Ί TIA
πŸ‘︎ 21
πŸ’¬︎
πŸ“…︎ Sep 03 2021
🚨︎ report
The relationship between autoantibodies targeting GPCRs and the renin-angiotensin system associates with COVID-19 severity medrxiv.org/content/10.11…
πŸ‘︎ 8
πŸ’¬︎
πŸ‘€︎ u/icloudbug
πŸ“…︎ Aug 27 2021
🚨︎ report
[f27]High aldosterone, normal renin.

Hi,

For almost two years now, I've had high aldosterone and no one seems to be able to work out why.

For a while it was thought that my diet might be too low in salt, so I upped my salt intake, which caused me to have hypokalemia and an increase in heart palpitations (and my aldosterone and renin levels stayed the pretty much the same as they were before)

My aldosterone is always between 1000 and 1500 pmol/l and my last renin was 8 pg/ml though I don't have the other renin values.

My blood pressure is not high, I do not have low magnesium, and I tested negative for gitelmans.

I've had a CT scan which didn't show a tumour.

If I eat a lot of salt, my potassium gets too low, but it seems to stay at the low end of normal if I follow a really low salt diet. And regardless of whether I have a normal or low salt diet my spot urine sodium is always <5 mmol/l and my spot urine potassium has ranged between 11 and 26 mmol/l.

Has anyone got any ideas what could be going on with me? My endocrinologist seems a bit stumped at the moment.

Thanks!

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/YGMIC
πŸ“…︎ Oct 08 2021
🚨︎ report
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system go.nature.com/2QUgDBn
πŸ‘︎ 553
πŸ’¬︎
πŸ‘€︎ u/Sirretv1
πŸ“…︎ Apr 26 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 5
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 13 2021
🚨︎ report
High Aldosterone but low blood pressure, normal potassium and renin

I haven’t been feeling great so my dr ordered a bunch of different tests. Everything came back normal except for high Aldosterone. Potassium and renin were normal and I actually have low blood pressure so my dr wanted me to retake the aldosterone test since I don’t really fit those symptoms. When I retook the test the results were even higher. Any idea why my aldosterone could be high but I don’t fit the symptoms? Should I be worried? Any tips on how to lower aldosterone levels?

Thanks!

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/Charming_Bug5866
πŸ“…︎ Jul 27 2021
🚨︎ report
Modulation of the renin-angiotensin system inhibits memory advantage for negative emotional material via decreasing hippocampus activation and its coupling with the amygdala biorxiv.org/content/10.11…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/sburgess86
πŸ“…︎ Aug 16 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 17
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 13 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 39
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience - Cureus Journal of Medical Science - September 20, 2020 cureus.com/articles/39950…
πŸ‘︎ 5
πŸ’¬︎
πŸ‘€︎ u/brokenB42morrow
πŸ“…︎ Aug 03 2021
🚨︎ report
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system nature.com/articles/s4146…
πŸ‘︎ 88
πŸ’¬︎
πŸ‘€︎ u/icloudbug
πŸ“…︎ Apr 24 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience - Cureus Journal of Medical Science - September 20, 2020 cureus.com/articles/39950…
πŸ‘︎ 14
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 11
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 13 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
The Renin-Angiotensin-Aldosterone System Main Menu Restart Sources Quiz Ready to start? This tutorial will take you through the RAA System (RAAS). Here's. - ppt download slideplayer.com/slide/884…
πŸ‘︎ 6
πŸ’¬︎
πŸ‘€︎ u/BigSurLynne19
πŸ“…︎ Jul 23 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 5
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 13 2021
🚨︎ report
Low renin and aldosterone and dhea .

I am a past steroid abuser. I quit when always getting hypoglycemia and nocturnal seizures. All tests pointed to hypoglycemia. Only have issues afterwards when being a pot head. So I quit that too. Now my labs are showing almost zero renin and aldosterone and 100 dhea. I am on trt at 8mg per day and have in range ultra sensitive estradiol without a ai. When I wear a cgm my bg curve is still showing adrenal insufficiencies. Would taking a 25 mg dhea make anything worse in terms of the adrenal response. I recently found that magnesium glycinate negativity impacted my mood and was causing adrenalized rushes like hypoglycemia but my bg was normal. It improved my 3am sleep maintenance Insomnia . I use acv and figure that's why my renin is low. My bp is normal.

Is low renin and aldosterone a bad thing?

I know low dhea at 46 years old isn't a great thing.

I still carry a shit load of muscle.. like Duane Johnson size. Little more roid gut. I'm 6'2 280 lb with a 36-in waist.

I am completely straight edge do not even use caffeine or alcohol and I drink 2 gallons of water a day and that keeps my urine just that straw color.

All of my endocrinologists are all clueless I've gone to Stanford and UCSF and most of them are just blaming my past steroid use.

I normally go 3 to 4 years between seizures unless I'm using marijuana and generally I'll begin getting hot flashes and tingly lips and shaky hands within about 2 months.

If anybody could give me some insight on what DHEA is going to do I'm getting the delivery from Amazon today and I'm just wondering if it's going to make anything substantially worse.

Hopefully you guys are all having a good day and I appreciate your help.

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/Bigtoddhere
πŸ“…︎ May 24 2021
🚨︎ report
Why does vitamin D seem to play a role in COVID-19? Interview with Dr. Roger Seheult of MedCram and Rhonda Patrick discuss COVID-19 and vitamin D (17:59), plausible biological mechanisms involving the renin-angiotensin system that might be underpinning this effect (32:07), and vaccines (01:43:27). youtube.com/watch?v=HxMEY…
πŸ‘︎ 39
πŸ’¬︎
πŸ‘€︎ u/rperciav
πŸ“…︎ Mar 05 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 3
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
RENIN
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/VielleichtEngel
πŸ“…︎ Mar 29 2021
🚨︎ report
COVID-19 pathophysiology may be driven by an imbalance in the renin-angiotensin-aldosterone system nature.com/articles/s4146…
πŸ‘︎ 16
πŸ’¬︎
πŸ‘€︎ u/D-R-AZ
πŸ“…︎ Apr 25 2021
🚨︎ report
Hypothalamic Renin-Angiotensin System and Lipid Metabolism: Effects of Virgin Olive Oil versus Butter in the Diet. (Pub Date: 2021-01-31)

https://doi.org/10.3390/nu13020480

https://pubmed.ncbi.nlm.nih.gov/33572630

Abstract

The brain renin-angiotensin system (RAS) has been recently involved in the homeostatic regulation of energy. Our goal was to analyse the influence of a diet rich in saturated fatty acids (butter) against one enriched in monounsaturated fatty acids (olive oil) on hypothalamic RAS, and their relationship with the metabolism of fatty acids. Increases in body weight and visceral fat, together with an increase in aminopeptidase A expression and reductions in AngII and AngIV were observed in the hypothalamus of animals fed with the butter diet. In this group, a marked reduction in the expression of genes related to lipid metabolism (LPL, CD36, and CPT-1) was observed in liver and muscle. No changes were found in terms of body weight, total visceral fat and the expression of hepatic genes related to fatty acid metabolism in the olive oil diet. The expressions of LPL and CD36 were reduced in the muscles, although the decrease was lower than in the butter diet. At the same time, the fasting levels of leptin were reduced, no changes were observed in the hypothalamic expression of aminopeptidase A and decreases were noted in the levels of AngII, AngIV and AngIII. These results support that the type of dietary fat is able to modify the hypothalamic profile of RAS and the body energy balance, related to changes in lipid metabolism.

------------------------------------------ Info ------------------------------------------

Open Access: True

Authors: Ana BelΓ©n Segarra - GermΓ‘n DomΓ­nguez-VΓ­as - JosΓ© Redondo - Magdalena MartΓ­nez-CaΓ±amero - Manuel RamΓ­rez-SΓ‘nchez - Isabel Prieto -

Additional links:

https://www.mdpi.com/2072-6643/13/2/480/pdf

πŸ‘︎ 48
πŸ’¬︎
πŸ‘€︎ u/Ricosss
πŸ“…︎ Feb 15 2021
🚨︎ report
The Association of Renin-Angiotensin-Aldosterone System Inhibitors With Outcomes Among a Predominantly Ethnic Minority Patient Population Hospitalized With COVID-19: The Bronx Experience cureus.com/articles/39950…
πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/CureusJournal
πŸ“…︎ Jul 14 2021
🚨︎ report
Renin-angiotensin-aldosterone (RAA pathway) question

For hormonal regulation for blood pressure, in my notes I have that when there’s a decrease in blood volume, then there’s a decrease in blood pressure so the kidneys will release renin which then gets converted into angiotensiogen. Angiotensinogen then converts ? To AT1 then AT2 which is active. It then will Vasoconstrict arteries to increase blood pressure or release aldosterone from the adrenals. The kidneys will retain sodium and water to increase blood volume and blood pressure. Is my pretty basic understanding correct or am I leaving stuff out? Also will AT2 vasoconstrict AND release aldosterone or will it do one or the other? Thanks!

πŸ‘︎ 4
πŸ’¬︎
πŸ‘€︎ u/MissDoubleHelix
πŸ“…︎ Mar 16 2021
🚨︎ report
Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride cochranelibrary.com/cdsr/…
πŸ‘︎ 5
πŸ’¬︎
πŸ‘€︎ u/psychfarm
πŸ“…︎ Feb 23 2021
🚨︎ report
Exposure to Renin-Angiotensin System Inhibitors Is Associated with Reduced Mortality of Older Hypertensive Covid-19 Patients medrxiv.org/content/10.11…
πŸ‘︎ 18
πŸ’¬︎
πŸ‘€︎ u/InInteraction
πŸ“…︎ Dec 17 2020
🚨︎ report
renin-angiotensin-aldosterone system

in response to a drop in BP, angiotensin II stimulates the adrenal glands to secrete aldosterone which will then cause the distal convoluted tubule to RETAIN sodium and water, meaning they are kept in the tubules and not reabsorbed back into the blood. how does this then result in blood volume increasing, and therefore BP too? no water is being reabsorbed.

πŸ‘︎ 8
πŸ’¬︎
πŸ“…︎ May 09 2021
🚨︎ report
F[27] High aldosterone, normal renin

Hello,

I've had a few blood tests now which have all showed that my aldosterone is high, but my renin is in the normal range. (Most recent test: Aldosterone 1350 pmol, renin 55.7)

My endocrinologist just wants to keep doing it again to see if it changes at any point, but that seems strange and my potassium is always borderline low, and I try to keep it up with eating a potassium rich diet.

Does anyone know what could be causing this?

πŸ‘︎ 3
πŸ’¬︎
πŸ‘€︎ u/YGMIC
πŸ“…︎ Feb 09 2021
🚨︎ report
High Aldosterone but low blood pressure, normal potassium and renin

I haven’t been feeling great so my dr ordered a bunch of different tests. Everything came back normal except for high Aldosterone. Potassium and renin were normal and I actually have low blood pressure so my dr wanted me to retake the aldosterone test since I don’t really fit those symptoms. When I retook the test the results were even higher. Any idea why my aldosterone could be high but I don’t fit the symptoms? Should I be worried? Any tips on how to lower aldosterone levels?

Thanks!

πŸ‘︎ 3
πŸ’¬︎
πŸ‘€︎ u/Charming_Bug5866
πŸ“…︎ Jul 27 2021
🚨︎ report
High Aldosterone but low blood pressure, normal potassium and renin

I haven’t been feeling great so my dr ordered a bunch of different tests. Everything came back normal except for high Aldosterone. Potassium and renin were normal and I actually have low blood pressure so my dr wanted me to retake the aldosterone test since I don’t really fit those symptoms. When I retook the test the results were even higher. Any idea why my aldosterone could be high but I don’t fit the symptoms? Should I be worried? Any tips on how to lower aldosterone levels?

Thanks!

πŸ‘︎ 2
πŸ’¬︎
πŸ‘€︎ u/Charming_Bug5866
πŸ“…︎ Jul 27 2021
🚨︎ report

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