I’ve been getting keratin treatments every 6 months for about 2 years. My hair is really fine so the shampoo my salon sells specifically for after the treatment is too heavy for me and weighs my hair down. I decided to buy a sulphate and paraben free shampoo on my own. Sulfate free was written really big on the front so I thought I was in the clear. Today as I was shampooing my hair I was reading the bottle in the shower (should have done this before, I know) and I saw Sodium C14-16 Olefin Sulfonate listed pretty high in the ingredients list.
I don’t know anything about Sulfonates as opposed to sulfates. Can someone tell me if this is still ok to use after my keratin treatment?? Thank you!
Edit: the brand I bought is Hairitage if that helps!
With borane-containing macrocyclic polyenes obtained by multi-step insertion of a strained alkyne into 9-borafluorene, the first direct crystallographic evidence of attractive borane–olefin interaction, which is beyond van der Waals force and governs the reactivity of the molecules, is provided.
Abstract
While attractive interactions between borane and olefin have been postulated to trigger various boron-mediated organic transformations, proximity structures of these functional groups, other than the formation of weak van der Waals complexes, have never been directly observed. Here we show that a close intramolecular borane–olefin interaction operates in macrocyclic systems containing borane and olefinic groups obtained by multi-step 1,2-carboboration between a strained alkyne and 9-borafluorene derivatives. Depending on Lewis acidity of the borane moiety and the size of the macrocycles, the magnitude of interaction changes, resulting in different reaction modes. The whole picture of the multi-step reactions has been revealed experimentally with theoretical supports. The present finding may not only provide a deeper understanding of the fundamental boron-mediated interaction but also lead to the development of new organic transformations involving molecular activation by boranes.
https://ift.tt/3ggy9KU
I have to use fragrance free shampoo for health reasons. I've had trouble finding one that doesn't burn my scalp.
I think I isolated the ingredient that's causing the burning by trying different shampoos and comparing their ingredients lists.
Free and Clear Shampoo is fine for me to use.
My scalp burns on contact with: Cleure Shampoo Kristin Ess Fragrance Free Daily Shampoo
They both contain Sodium C14-16 Olefin Sulfonate.
Are there other names for Sodium C14-16 Olefin Sulfonate? Is it related to other things I'm likely to be allergic to also?
Also, Cleure has polyquaternium-10 Kristin Ess has polyquaternium-71 Are these two ingredients different enough that polyquaternium is not the allergen?
Thanks!
I wasn't sure if this should go here or in the allergies subreddit.
Oxygen atom transfer (OAT) reactivity of a non‐heme [Fe IV (2PyN2Q)(O)] 2+ ( 2 ) containing sterically bulky quinoline‐pyridine pentadentate ligand (2PyN2Q) has been thoroughly studied with different olefins. The ferryl‐oxo complex 2 shows excellent OAT reactivity during epoxidations. The steric encumbrance and electronic effect of the ligand influence the mechanistic shuttle between oxygen atom transfer pathway I (OAT) and isomerization pathway II (during the reaction stereo pure olefins), resulting in a mixture of cis ‐ trans epoxide products. On the contrary, the sterically less hindered and electronically different [Fe IV (N4Py)(O)] 2+ ( 1 ) provides only cis ‐stilbene epoxide. The Hammett study (with different para ‐substituted styrene derivatives), i.e. log( k H / k X ) against σ P + (considering polarity and resonance effect) shows a liner plot with reaction constant, ρ + = ‐1 suggesting the role of dominant inductive electronic as well as resonance effect during electron transfer from olefin to 2 in the rate‐limiting step . Additionally, the computational study supports the involvement of stepwise pathways during olefin epoxidation. The ferryl bend due to the bulkier ligand incorporation leads to destabilization of both d z 2 and d x 2 ‐y 2 orbital, leading to a very small quintet‐triplet gap and enhanced reactivity for [Fe IV (2PyN2Q)(O)] 2+ compared to [Fe IV (N4Py)(O)] 2+ . Thus, the present study unveils the role of steric and electronic effects of the ligand towards mechanistic modification during olefin epoxidation.
https://ift.tt/3d7dIy4
Various iron catalyst systems featuring a range of different ligands have been evaluated for the Wacker‐type oxidation of olefins to ketones in the presence of phenylsilane at room temperature and ambient air. The transformation is operationally simple, sustainable, exhibits a high functional group tolerance, and is applicable to natural product synthesis.
Abstract
Herein, we describe a convenient and general method for the oxidation of olefins to ketones using either tris(dibenzoylmethanato)iron(III) [Fe(dbm)3] or a combination of iron(II) chloride and neocuproine (2,9‐dimethyl‐1,10‐phenanthroline) as catalysts and phenylsilane (PhSiH3) as additive. All reactions proceed efficiently at room temperature using air as sole oxidant. This transformation has been applied to a variety of substrates, is operationally simple, proceeds under mild reaction conditions, and shows a high functional‐group tolerance. The ketones are formed smoothly in up to 97 % yield and with 100 % regioselectivity, while the corresponding alcohols were observed as by‐products. Labeling experiments showed that an incorporated hydrogen atom originates from the phenylsilane. The oxygen atom of the ketone as well as of the alcohol derives from the ambient atmosphere.
https://ift.tt/3af8zSt
Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c01967
He Huang and Tristan H. Lambert
https://ift.tt/3b7HG3w
Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c02117
Alexander W. Schuppe, James Levi Knippel, Gustavo M. Borrajo-Calleja, and Stephen L. Buchwald
https://ift.tt/3cyZk19
A highly modular, site‐selective 1,1‐difunctionalization of unactivated olefins en route to versatile bis‐organometallic B,B(Si)‐reagents was developed by nickel catalyzed chain‐walking events. This protocol is characterized by exceptional reaction rates, mild conditions, broad scope, excellent chemo‐ and regioselectivity, thus unlocking a new technique for preparing densely functionalized 1,2‐bisorganometallic reagents from simple distinct, yet widely available, electrophilic partners.
Abstract
A catalytic 1,1‐difunctionalization of unactivated olefins en route to sp3bis‐organometallic B,B(Si)‐reagents is described. The protocol is characterized by exceptional reaction rates, mild conditions, wide scope, and exquisite selectivity pattern, constituting a new platform to access sp3bis‐organometallics.
https://ift.tt/3dT0DaM
Journal of the American Chemical SocietyDOI: 10.1021/jacs.0c13077
Mark W. Campbell, Mingbin Yuan, Viktor C. Polites, Osvaldo Gutierrez, and Gary A. Molander
https://ift.tt/2OofX5S
Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c02050
Sota Akiyama, Natsuki Oyama, Tsubura Endo, Koji Kubota, and Hajime Ito
https://ift.tt/3u8OgO4
Iron catalysis provides a highly regioselective and stereoretentive union of olefins with haloalkenes and bis(pinacolato)diboron to give homoallylic boronates. Unlike previous pathways, these reactions proceed through stereospecific carbometallation‐β‐halide elimination. The method is amenable to complex molecule and gram‐scale synthesis.
Abstract
The first examples of an iron‐catalyzed three‐component synthesis of homoallylic boronates from regioselective union of bis(pinacolato)diboron, an alkenyl halide (bromide, chloride or fluoride), and an olefin are disclosed. Products that bear tertiary or quaternary carbon centers could be generated in up to 87 % yield as single regioisomers with complete retention of the olefin stereochemistry. With cyclopropylidene‐containing substrates, ring cleavage leading to trisubstituted E‐alkenylboronates were selectively obtained. Mechanistic studies revealed reaction attributes that are distinct from previously reported alkene carboboration pathways.
https://ift.tt/2H4gKpc
With borane-containing macrocyclic polyenes obtained by multi-step insertion of a strained alkyne into 9-borafluorene, the first direct crystallographic evidence of attractive borane–olefin interaction, which is beyond van der Waals force and governs the reactivity of the molecules, is provided.
Abstract
While attractive interactions between borane and olefin have been postulated to trigger various boron-mediated organic transformations, proximity structures of these functional groups, other than the formation of weak van der Waals complexes, have never been directly observed. Here we show that a close intramolecular borane–olefin interaction operates in macrocyclic systems containing borane and olefinic groups obtained by multi-step 1,2-carboboration between a strained alkyne and 9-borafluorene derivatives. Depending on Lewis acidity of the borane moiety and the size of the macrocycles, the magnitude of interaction changes, resulting in different reaction modes. The whole picture of the multi-step reactions has been revealed experimentally with theoretical supports. The present finding may not only provide a deeper understanding of the fundamental boron-mediated interaction but also lead to the development of new organic transformations involving molecular activation by boranes.
https://ift.tt/2RARbBv
While attractive interactions between borane and olefin have been postulated to trigger various boron‐mediated organic transformations, proximity structures of these functional groups, other than the formation of weak van der Waals complexes, have never been directly observed. Here we show that a close intramolecular borane‐olefin interaction operates in macrocyclic systems containing borane and olefinic groups obtained by multi‐step 1,2‐carboboration between a strained alkyne and 9‐borafluorene derivatives. Depending on Lewis acidity of the borane moiety and the size of the macrocycles, the magnitude of interaction changes, resulting in different reaction modes. The whole picture of the multi‐step reactions has been revealed experimentally with theoretical supports. The present finding may not only provide a deeper understanding of the fundamental boron‐mediated interaction but also lead to the development of new organic transformations involving molecular activation by boranes.
https://ift.tt/3ggy9KU
The steric and electronic effects exerted by the bulky quinoline‐pyridine pentadentate ligand (2PyN2Q) in the non‐heme complex [FeIV(2PyN2Q)(O)]2+ play a key role in olefin epoxidation by oxygen atom transfer and trigger mechanistic diversification. In the present study, the mechanism of olefin epoxidation was thoroughly investigated and rationalized with a detailed computational study.
Abstract
The oxygen atom transfer (OAT) reactivity of the non‐heme [FeIV(2PyN2Q)(O)]2+ (2) containing the sterically bulky quinoline‐pyridine pentadentate ligand (2PyN2Q) has been thoroughly studied with different olefins. The ferryl‐oxo complex 2 shows excellent OAT reactivity during epoxidations. The steric encumbrance and electronic effect of the ligand influence the mechanistic shuttle between OAT pathway I and isomerization pathway II (during the reaction stereo pure olefins), resulting in a mixture of cis‐trans epoxide products. In contrast, the sterically less hindered and electronically different [FeIV(N4Py)(O)]2+ (1) provides only cis‐stilbene epoxide. A Hammett study suggests the role of dominant inductive electronic along with minor resonance effect during electron transfer from olefin to 2 in the rate‐limiting step. Additionally, a computational study supports the involvement of stepwise pathways during olefin epoxidation. The ferryl bend due to the bulkier ligand incorporation leads to destabilization of both and orbitals, leading to a very small quintet–triplet gap and enhanced reactivity for 2 compared to 1. Thus, the present study unveils the role of steric and electronic effects of the ligand towards mechanistic modification during olefin epoxidation
https://ift.tt/3d7dIy4
Herein, we describe a convenient and general method for the oxidation of olefins to ketones using either tris(dibenzoylmethanato)iron(III) [Fe(dbm) 3 ] or a combination of iron(II) chloride and neocuproine (2,9‐dimethyl‐1,10‐phenanthroline) as catalysts and phenylsilane PhSiH 3 as additive. All reactions proceed efficiently at room temperature using air as sole oxidant. This transformation has been applied to a variety of substrates, is operationally simple, proceeds under mild reaction conditions, and shows a high functional‐group tolerance. The ketones are formed smoothly in up to 97 % yield and with 100 % regioselectivity for ketone formation, while the corresponding alcohols were observed as by‐products. Labeling experiments showed that an incorporated hydrogen atom originates from the phenylsilane. The oxygen atom of the ketone as well as of the alcohol derives from the ambient atmosphere.
https://ift.tt/3af8zSt
A catalytic 1,1‐difunctionalization of unactivated olefins en route to sp3 bis‐organometallic B,B(Si)‐reagents is described. The protocol is characterized by exceptional reaction rates, mild conditions, wide scope, and exquisite selectivity pattern, constituting a new platform to access sp3 bis‐organometallics
https://ift.tt/3bzflCu
