I am a 37 years old male, obese, yesterday I had the monoclonal antibody treatment that works against omicron but I still don’t see any improvement, I am now on day 7 of symptoms and my temperature is in the 99-100 range, I am very scared , I don’t know what do , I thought the monoclonal antibody treatment will work because it has worked literally for everybody but me
I am vaxxed and recently boosted (12/21). Started having cold-like symptoms on Tuesday. Pretty intense headache, simultaneous stuffy head and runny nose, post-nasal drip and accompanying scratchy throat, fever a little over 100°. Similar story on Wednesday, but by Wednesday night I could feel it starting to move lower in my respiratory system. Thursday morning my chest was painful and tight, and proceeded to get more pronounced throughout the day. On Thursday my order of BinaxNow test kits from Walmart arrived and when I tested, the dark purple positive stripe appeared as soon as the solution moved up the test strip.
Since I have a comorbidity that puts me at higher risk of severe Covid, I qualified for monoclonal antibodies treatment. I was able to get an appointment the next morning through the state of Colorado portal (they’ve done a great job with this). This morning when I went in for the treatment, I was having some pretty uncomfortable chest tightness and a painful, unproductive cough.
I received the sotrovimab monoclonal antibodies treatment seven hours ago and the impact is stunning. The fatigue and exhaustion I was feeling is gone, all nasal symptoms and throat symptoms have disappeared, and my chest now feels like at the very end of a cold, when you have no pain and no tightness and you’re just coughing up crap. I would have chalked this up to psychological effect, but the nurses administering the treatment told me that every person who gets it feels better immediately and they believe it has to be more than just in their patients’ heads. I really believe it now. If you are at higher risk of severe Covid, even if fully vaccinated, I recommend you seeking this treatment within the first five days of the onset of symptoms. I’ve never had a U-turn like this with an illness in my life. It’s nothing short of amazing.
EDIT: Because everyone keeps bringing this up: Yes, Monoclonal antibodies are an effective treatment for COVID. My point is that monoclonal antibodies are way too costly, and treating the population at large as soon as they show their first symptoms requires infrastructure that simply does not exist, and this is why I am making this point.
Since the recent podcast with Dr. McCullough has created quite a stir on here, I want to quickly go through why the logic of "early, aggressive treatment prior to hospitalization" using antibodies is not a viable way of overcoming the pandemic, and why the vaccine is still one of the most important ways to control the pandemic.
Preface: What are monoclonal antibodies? Why are they so expensive?
Antibodies are proteins that a specific type of white blood cells, called B lymphocytes, produce. When these cells are confronted with an antigen, such as the Spike protein of SARS-CoV2, they produce these antibodies in the attempt of obstructing the surface of these spike proteins. Because Spike proteins need to bind to a receptor called ACE2 to mediate the invasion of the host, and because they need to invade a host cell to replicate, some of these antibodies will disrupt the interaction between Spike and ACE2 and make it much more difficult to replicate. Now, an immune system makes many different antibodies for each antigen, because the immune system has no way of knowing which part of the spike protein actually needs to be obstructed, so the immune system has a shotgun approach - this is important, because it also gives some additional resistance to potential mutations by virtue of the fact that an immune system will have a larger repertoire to combat the antigen.
How are monoclonal antibodies different? The term "monoclonal" means that the antibody originates from a single clone. How is this done? Basically, a mouse is either vaccinated with the mRNA for the spike protein or the spike protein itself, and its B-lymphocytes will produce antibodies much like our human immune system does. These b-lymphocytes are then extracted from the mouse, usually the spleen, and are separated from each other before being fused with human cancer cells to produce so-called "hybridoma" cells that are immortalized and can replicate and shed the antibody for extended periods of time. Then, individual cells are taken and left to replicate and produce antibody, before their ability to bind to the spike protein is measured using biophysical m
... keep reading on reddit ➡Since I know a lot of COVID info can be confusing, I wanted to share my experience getting the county’s monoclonal antibody treatment today.
I went to Chicago this weekend to help out family… mask rules are a little tighter up there, but it seems as though somewhere on the trip I got COVID. I am double vaxxed (Moderna) and boostered (Pfizer).
I woke up this AM with a couple symptoms so bought a double set of the BinaxNow home tests and both were positive back to back. Sigh.
I live very close to the Hillsborough County Monoclonal Treatment “Center”, so I decided to skip dealing with the website and making an appointment and just drive the .5 miles over there.
Location is West Tampa Community Resource Center, 2103 N. Rome Ave., Tampa, FL 33607.
I wore two masks and still felt really weird walking in, but the staff immediately informed me that “most people who come in here are positive so don’t worry.” Ok, still worried, but I followed their direction.
Even without an appointment there was not a soul in line so I was seen immediately. I had to give my drivers license and insurance card (although they said “if I had one”), and after answering a few basic questions about allergies and some waivers, I was in.
They are also very eager to give you food and water… I guess you can’t take the shots on an empty stomach. I was weary of taking my masks off to eat the provided snacks but luckily I ate right before heading out.
I was brought pretty quickly back to one of the treatment rooms. They are really bare bones… empty room with a fold out table and a tech.
I was not thrilled when the tech told me the treatment is 4 shots… one in the back of each arm and two in the lower stomach (!!!!). But she did say it is supposed to reduce symptoms and risk of hospitalization within 24 hours. It can also reduce future risk of infection.
However, it doesn’t make you magically “non-positive,” so that still needs to be monitored.
An actual nurse is called into the room to administer the shots. I’m good with needles but they were a bit intimidating… long and lots of fluid. He informed me that it would sting quite a bit but not for very long.
I was most worried about the stomach ones, but the very first arm one hurt the most. None of the others felt super either, but he was right about the pain being short-lived.
I’m only about 20 minutes into walking into the building at this point, but you have to sit in a room for 45 minutes to makes sure you have no adverse reacti
... keep reading on reddit ➡Video with nurse turning him down https://twitter.com/Harrison_of_TX/status/1459591738809622532?s=20
Video of phone call to hotline https://twitter.com/realDaveReilly/status/1459555435329966083?s=20
Texas criteria for monoclonal antibodies that includes black or latinx as a qualifier (high risk ethnic groups) https://macarthurmc.com/north-texas-obgyns-need-to-know-about-monoclonal-antibodies-for-covid-19/
I'm visiting from out of town and just got covid. I am having really grueling symptoms and need to get treatment asap. Does anyone know where I can go for this? Is there a website for locations? Thank you in advance.
Infectious disease specialist Dr. Stephen Lee, who has led the program’s clinical rollout along with Takaya, said eligibility has recently expanded to all immunocompromised people, including those who are fully vaccinated.
“We’re always looking to expand eligibility. But we only do it when we feel that it is safe to do so,” Lee said.
