Hox genes regulate asexual reproductive behavior and tissue segmentation in adult animals [Nature] nature.com/articles/s4146…
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πŸ‘€οΈŽ u/Ginkgopsida
πŸ“…οΈŽ Jan 14 2022
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Hox gene mutant fluffy (art:u/AbaloneShuttle)
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πŸ‘€οΈŽ u/AbaloneShuttle
πŸ“…οΈŽ Apr 20 2021
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Hox Gene Question

β€œDescribe and explain two processes that account for the differences in the number of his genes present in humans, when compared to those present in the worm C Elegans.”

One process could be hox gene inversions causing duplications, and the other translocation ?? I don’t really understand either of these... any help would be greatly appreciated!

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πŸ‘€οΈŽ u/Embarrassed-Set-3820
πŸ“…οΈŽ May 19 2021
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The anterior Hox gene ceh-13 and elt-1/GATA activate the posterior Hox genes nob-1 and php-3 to specify posterior lineages in the C. elegans embryo biorxiv.org/content/10.11…
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πŸ‘€οΈŽ u/sburgess86
πŸ“…οΈŽ Feb 09 2021
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Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster - Temporal and spatial colinear expression of the Hox genes determines the specification of positional identities during vertebrate development nature.com/articles/s4200…
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πŸ‘€οΈŽ u/Regenerative_Med_Bot
πŸ“…οΈŽ Dec 29 2020
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Functional characterization of human Homeodomain-interacting protein kinases (HIPKs) in Drosophila melanogaster reveal both conserved functions and differential induction of HOX gene expression biorxiv.org/content/10.11…
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πŸ‘€οΈŽ u/sburgess86
πŸ“…οΈŽ Nov 04 2020
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What's the difference between homeotic, homeobox, and hox genes?

I know that the HOX genes are a subregion within the homeobox, but I'm unsure how those relate to homeotic genes. All I'm fully sure of is that they all contribute to the spatial organization of organs and body parts during embryonic development.

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πŸ‘€οΈŽ u/egomei
πŸ“…οΈŽ Apr 10 2020
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TIL Hox genes, a subset of homeobox genes, are a group of related genes that specify regions of the body plan of an embryo along the head-tail axis of animals. Hox proteins encode and specify the characteristics of position, ensuring that the correct structures form in the correct places of the body en.wikipedia.org/wiki/Hox…
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πŸ‘€οΈŽ u/chercheur17
πŸ“…οΈŽ Sep 16 2019
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What do IDiots ignore. HOX gene studies, the concept of extinction, Darwin's actual words on gradualism and the fossil record... donotlink.it/wqlV
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πŸ‘€οΈŽ u/ryu238
πŸ“…οΈŽ Sep 27 2018
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The song Head, Shoulders, Knees, and Toes almost perfectly describes the HOX genes, which were discovered 20 years later.
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πŸ‘€οΈŽ u/slxpluvs
πŸ“…οΈŽ May 26 2019
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OP inserts elephant hox genes into a strawberry, all for that sweet, fruity karma
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πŸ‘€οΈŽ u/Pythagoras180
πŸ“…οΈŽ Jan 19 2019
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Hox genes and body plans youtu.be/MwuOyew_0Ws
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πŸ‘€οΈŽ u/TheZigRat
πŸ“…οΈŽ Aug 30 2019
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Why are *Hox* genes found in the genome organized by body location?

TLDR: Why are Hox genes physically ordered within the (fruit fly, and presumably human) genome in the physical order in which they are expressed in the body? Does it have something to do with recombination?

I came across this curious fact in Endless Forms Most Beautiful, having earlier heard it mentioned in Your Inner Fish. Both books mentioned the miraculous fact that Hox genes, which control ultra basic developmental functions such as eye and limb formation, are found in the genome in the general order of the body. That is, developmental genes (in a fruit fly, but us too) influencing the head are in a cluster, then genes influencing the thorax, then genes influencing the abdomen. At least, this is what I think they said. Both books mentioned it as a miraculous occurrence, but neither told why it has to be that way. Why the heck should the physical order of genes in DNA matter, so long as the genes are on the proper chromosomes and are properly expressed? Might they be linked to reduce the likelihood that recombination messes things up? Even still, that wouldn't answer why the order is so precise. If all of the Hox genes are linked, then you could reduce recombination by having "head, abdomen, thorax" just as well as "head, thorax, abdomen."

Hopefully this is coherent, I don't really understand the subject well enough to phrase a proper question.

Thanks!

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πŸ‘€οΈŽ u/Pardner
πŸ“…οΈŽ Aug 17 2011
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Mutated HOX gene in a gecko
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πŸ‘€οΈŽ u/ChubsTheBullDog
πŸ“…οΈŽ Feb 26 2015
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X files breaks down the HOX gene WITH STYLE

http://www.criticalcommons.org/Members/pthurtle/clips/x-files-season-5-episode-5-the-post-modern-1/view

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πŸ‘€οΈŽ u/Sitka_Spruce_Bruce
πŸ“…οΈŽ Feb 27 2019
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Is spatial colinearity in Hox gene expression coincidental or adaptive?

Asked on /r/askscience but thought I might try my luck here.

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πŸ‘€οΈŽ u/ninsinsnins
πŸ“…οΈŽ May 26 2014
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What is the difference between Hox Genes, Regulatory Genes and Gene Switches?

I am having difficulty differentiating the three. Are Hox Genes and Gene Switches both Regulatory Genes or are they something different? My sources don't specify clearly enough.

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πŸ‘€οΈŽ u/Bsillly
πŸ“…οΈŽ Feb 16 2016
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Whats the difference between epistasis and Hox genes?
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πŸ‘€οΈŽ u/fml_student
πŸ“…οΈŽ May 07 2018
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A new study from EPFL and the University of Geneva reveals a β€œcode” of architect Hox genes that are expressed in specific combinations during the development of hands and fingers. actu.epfl.ch/news/the-gen…
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πŸ‘€οΈŽ u/spesaeterna
πŸ“…οΈŽ Sep 21 2018
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Reassessing the Role of Hox Genes during Vertebrate Development and Evolution cell.com/trends/genetics/…
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πŸ‘€οΈŽ u/burtzev
πŸ“…οΈŽ Feb 26 2018
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What's the difference between homeobox, homeotic, and hox genes?

From what I understand, homeobox genes are a large family of genes involved in directing the body structure formation.

Homeotic genes controls the identity of body parts and the proteins it codes for are transcription factors. Mutations of the homeotic genes cause structures to form in the wrong place.

Hox genes are responsible for directing the body plan along the AP axis and the proteins it codes for are transcription factors. They're a subset of the homeobox family.

Is my understanding correct? If so, what's the distinction between homeotic genes and hox genes? Are hox genes are subset of homeotic genes in that they direct the body plan along the AP axis while homeotic genes are responsible for all axes? Any help on clearing this up would be greatly appreciated!

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πŸ‘€οΈŽ u/BlampCat
πŸ“…οΈŽ Apr 25 2016
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Developmental Biology and Evolution question-- How did single celled organisms develop Hox cluster genes?

I know these probably started out as one gene, as the Hox cluster found in eukaryotes is mostly copies of one ancestral gene. My question is concerning how the single celled organisms evolved into multicellular ones, and specialized enough to allow the Hox clusters to help directional development. Did cingle celled organisms initially form colonies in which different cells specialized in function? When does an organism go from being colonial (like a slime mold or even the man o war) to multicellular?

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πŸ‘€οΈŽ u/Arevalous
πŸ“…οΈŽ Dec 18 2012
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The relationship between Hox genes and development of the proprioceptive system?

So recently a paper by Zelzer. E et al. in Developmental cell have shown a possible link between the Hox cluster and the development of the spinocerebellar neurons which contribute to the proprioceptive system. Does anyone know any further information of how the Hox genes contribute to the neural system?

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πŸ‘€οΈŽ u/ekum2
πŸ“…οΈŽ Nov 14 2017
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