Hi, so I've been struggling with the same problem for years now: every time I begin my iron supplementation again, I end up getting so backed up that I have no other choice but to stop taking my iron, and I've tried numerous forms of iron along with stool softener but nothing seems to work. Is there anyone else who's found a regime that works? I'm sick of picking and choosing which aspect of my health to prioritize :( And my doctor is no help he just says to try different forms of iron which I have. Currently taking iron bisglycinate which is supposed to be easier on the GI tract but it literally stopped my digestive system. So frustrated!
pt info: 21f. 5'3. 125 lbs. USA. Hispanic/asian. non-drinker/nonsmoker. regularly take Zoloft and vistaril and Vyvanse but it's never caused me problems. Lifelong issues with very mild stomach aches, diarrhea, and constipation. Last time things were this bad I went to the er, got steroids and zofran. Have a Dr's appt on may 16.
When I started my period last week I had some INTENSE stomach pain and diarrhea. Par for the course for me. Took Imodium and gas x and that helped for about 2 days. Then the constipation starts, stopped taking Imodium but kept taking the gas x. The stomach cramps are starting to become frequent, about every other hour following a meal/snack. Now it's a week later, I am constipated with diarrhea and bloating/gas pains every 15 minutes. My period is over but the GI problems are still here and worsening.
Here's a list of OTC meds that haven't worked: Imodium, Omeprazole, gas x, Tylenol, ibuprofen. Tldr: week long gas and diarrhea along with more frequent stomach cramps.
My title probably doesn’t make sense but how do you know if your GI issues are caused by extreme weight loss screwing up your whole GI tract or are uh real issues with your GI tract?
I do know that people during anorexia recovery get GI disorder symptoms but I’m not sure if their GI disorder symptoms are as painful or.....
I hope my question isn’t insensitive or triggering Ö
25, female 180lb 5’8” History of autoimmune, hEDS, brain injury, and arthritis. I don’t take any meds that would mess with my GI tract like this.
At least once a week I get cramps that feel a lot like short bursts of bad period cramps and then within an hour or so I have diarrhea. It’s not food related because it doesn’t happen with the same food twice. Is this normal? Does everyone have this?
Missed a "
If you removed the GI tract from the human body, while empty, how much would it weigh? I’m talking esophagus to rectum. Probably not including things that happen after nutrition is absorbed, like kidneys, liver or bladder. What percentage of body mass is the GI tract? I want to know for a story I’m writing. I keep trying to look it up, but all I can find is intestines (7.5 pounds together). The character is a thin tall woman, if that helps any estimate.
For folks who have GI neuropathy: has it ever been hard for you to pass gas?
I ask because I have this searing upper back pain between my shoulder blades and it seems to go away when I can pass gas, but I can’t do that very often due to neuropathy/autonomic dysfunction.
I’m trying to see if anyone has had a similar experience. My doctors are stumped. Thank you.
But Imma pull a Josh n just let it sort itself out..
Hello everyone,
While I understand there is a connection between 5-HT2A and intestinal mucosa regulation (growth/proliferation, inflammation, etc.) this is not via 5-HT2 activation within the GI tract. However I have seen multiple sources "state" that 5-HT2A is distributed in the GI tract, but none of their sources (that they cite) actually confirm this.
I.E.
The source for wikipeida: .https://www.diva-portal.org/smash/get/diva2:586490/FULLTEXT02.pdf 5-
>HT2A receptors have in addition to neuronal cells been shown to be present in many other tissues and cell types [different cell types in the bowel [34], and urinary tract [44].]
The source of that source of another source:
https://accesspharmacy.mhmedical.com/content.aspx?bookid=1613&Sectionid=102158475
>5-HT2A receptors in the GI tract are thought to correspond to the D subtype of 5-HT receptor originally described by Gaddum and Picarelli (1957)
I have yet to see any evidence that 5-HT2A is actively expressed in the GI tract (e.g. intestinal epithelial cells). I know for example 5-HT2B is expressed in the GI tract quite extensively https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1573235/ , yet I see no evidence of 5-HT2A expression, so I don't know why all these sources keep stating it does.
I think it should be daily for most people.
I’m taking it as a sign things are working. I’m not nauseous or uncomfortable. Losing regularity with my bowel movements. Anyone else experience all this noise coming from below? Or have an estimate how long it’ll last? I don’t remember from the last time I went keto tbh
I have nerve pain up and down my spine, but especially in the upper portion, when I eat. It’s there when I don’t eat as well but I can especially feel I when I’m swallowing.
Like I can literally feel the food moving down as pain in my spine (referred pain from my esophagus) and pain and squeezing between my shoulder blades and just below them as it enters my stomach.
Then when it’s in my stomach I feel pain in my ribs. The pain is always there but more when I’m eating.
I can’t tell if it’s strictly related to eating because the pain is always there to some degree, I just think it’s worse when I’m eating. I have to start keeping a journal or something. It hurts to lie down on my upper back because it’s so hot and in nerve-y pain all the time. My doctor told me I have allodynia.
Other pain is in my elbows.
Does anyone else get this? Has anything helped?
Apparently my dog has a delicate stomach. I got her about four months ago and started her on Purina Pro Plan (chicken flavored, which she loved), but her stool was generally quite soft (think soft serve - sometimes worse). I moved her to a limited ingredient blend (turkey and potato I think?) from Blue Buffalo and it was slightly better, but not a whole lot. I tried another grain free food (Taste of the Wild, High Prairie blend) which was about the same, so I took a stool sample to the vet. They didn't find worms, but gave her dewormer anyways, as well as some antibiotics and probiotics, and some real fancy and expensive Royal Canin GI food that resulted in no significant improvement. Once I ran out of that, I went back to the TotW grain free and her stool finally looks good. However, the vet noted there's been a link between grain free and dilated cardiomyopathy.
SO, with that finally all out of the way, I'm looking for a food that's not $4/lb and an alternative to grain free but still has a good chance of working at keeping her stool nice and solid. I'm looking at trying PPP's sensitive skin and stomach one and maybe one of Hill's science diet blends. Anyone have any recommendations? Thanks!
Was just curious if the sludge accumulates or pools in the GI tract at all.
edit: not sure why I'm being downvoted, this is a question about the biochemistry of nutrient uptake. As in, what biochemical processes govern uptake specificity by intestinal cells.
Basically I was eating shrimp and wondered why they turn pink after cooking. Looked it up and learnt its because of a red photopigment that is liberated from a protein complex during heating. The photopigment is another obscure, small-molecule compound, not unlike the hundreds of thousands of other biological molecules found on Earth.
So now I'm wondering: what exact mechanisms dictate what molecules will be taken up by intestinal epithelia? Like sugars, fats, amino acids are self explanatory but what about the more exotic compounds like carotenoids, various hormones/small messengers, FDA approved drugs, etc. Are there specific transporters for each molecule, transporters that recognize broad classes of molecules, or are molecules indiscriminately absorbed? There are thousands of biological molecules, so how does the body efficiently decide who gets in and who doesn't? Pubmed is not being super useful.
Female, 30, white, 5’1, 110 lb, non smoker, do not drink, take Pepcid 40 mg and Carafate. Other medical hx includes ulcers and diverticulitis.
I have had severe menstrual pain and discomfort since I was about 17. The pain from my uterus is bad, between 6 to 9 out of 10 for the first 2 days at any given time, with nausea and vomiting some months.
I also get chest pain, but most doctors think it’s musculoskeletal. The pain radiates thru my back and thighs. I’ve always taken ibuprofen; however, I was recently diagnosed with ulcerative colitis and told not to ever take NSAIDs again by my GI.
I don’t know what to take. 2 extra strength Tylenol barely even dulls the pain. I’ve been on 3 different types of birth control. One caused severe gastritis, the other caused me to cry all the time and the third actually made my period worse. Furthermore, I would prefer not to take something everyday for a problem that happens 2 days a month.
Are there any other options?? I cannot lay in bed with a heat pack and miserable for 2 days every month and miss work, etc. but I don’t want to destroy my GI tract either.
Any ideas would be appreciated, thank you.
