A list of puns related to "Connectomics"
https://www.biorxiv.org/content/10.1101/2021.04.24.441207v2
Smart brain implants will revolutionize neurotechnology for improving the quality of life in patients with brain disorders. The treatment of Parkinson's disease (PD) with neural implants for deep brain stimulation presents an avenue for developing machine-learning based individualized treatments to refine human motor control. We developed an optimized movement decoding approach to predict grip-force based on sensorimotor electrocorticography and subthalamic local field potentials in PD. We demonstrate that electrocorticography combined with Bayesian optimized extreme gradient boosted decision trees outperform other machine learning approaches. We elucidate a link between dopamine and movement coding capacity in PD, by showing negative correlations between decoding performance and motor symptom severity in the medication OFF state. Finally, we introduce an approach that leverages wholebrain connectomics to predict machine-learning based decoding performance in invasive neurophysiology. Our study provides a framework to aid development of intelligent adaptive deep brain stimulation.
Joining us today are Jörgen Kornfeld (u/jmrkor) and Bobby Kasthuri (u/BobbyKasthuri).
Jörgen's introduction:
>Joergen loves thinking about neural networks (real and artificial) since high-school and is still doing that pretty much every day. He has a MSc in computational biology from ETH Zurich and a PhD from Heidelberg University and has now over 10 years of experience in connectomics, machine learning and the analysis of massive microscopy datasets. For his doctoral studies he worked with Prof. Winfried Denk at the Max Planck Institute of Neurobiology in Munich and is now a postdoctoral researcher with Prof. Michale Fee at the Massachusetts Institute of Technology in Cambridge. Joergen collaborates closely with laboratories at the New York University and Google Research. In 2017 he co-founded ariadne.ai, a startup dedicated to making automated image analysis of large microscopy datasets available to the wider scientific community. Scientific question that keeps him up at night: To which degree can we infer the dynamics of neurons from a static connectivity map?
Bobby's introduction:
>Hi, my name is Bobby Kasthuri and I am an assistant professor in the department of neurobiology at the University of Chicago and a neuroscientist at Argonne National Laboratory. I am interested in mapping how every neuron in a brain connects to every other neuron (connectomics). We hope to develop these brain maps across species, young and old brains, and normal and diseased brains. We hope to use these maps to better understand how brains grow up and change with evolution, aging, and disease.
Let's discuss connectomics!
Related links:
We take the chance to wish everyone from the US a happy thanksgiving!
On Thursday, November 28th we will be joined by
for an AMA on connectomics. A dedicated thread will be posted on Thursday. We hope to see you then!
Do you want to keep up with exciting research in neuroengineering? If so, you’ll want to check out my timeline of events in neurotechnology, connectomics, and brain simulation. With a single-paragraph explanation for each, I summarize 88 events relevant to these fields and organize them by year (from 2005 to 2019). I hope that you enjoy reading about these exciting breakthroughs!
Senior director in Intel's AI products group Casimir Wierzynski talks to us about the development of connectomics, building 3-D visualizations of neurons, and why the bottleneck to mapping the mind is still the computational step.
Article link: https://blog.paperspace.com/the-magic-of-connectomics/
Hi all, i'm relatively new to this subreddit but i wanted to make a post about an upcoming free educational webinar that the company i work for : Omniscient Neurotechnology will be hosting on the benefits of network connectomics and how machine learning and cloud computing software can be utilised to advance research in the fields of neuroscience and neuropsychology.
The webinar is titled Connectomics: Turning Your Center Into a Precision Brain Medicine Institution, and features our founder and neurosurgeon Dr Michael Sughrue alongside various guest speakers in two different time zones.
As a company we have built a clinical grade image preprocessing and analysis pipeline (Similar to the likes of SPM and Python), but also wanted to give back and engage with the broader scientific community. As such also built a free version of this pipeline called "Labs" (hence my reddit name). I myself am currently in the process of completing a PhD in neuroscience at the University of Sydney, and agreed to be a part of this company on a part time basis based on the genuine interest they have shown with fostering a positive research community and providing educational content like this webinar that can benefit researchers interested in this field. So if this is something you would be interested in you can click the links below to sign up!
Please feel free to ask me any quest
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