Do we know the mechanism by which the Caudate shrinks, making the lateral ventricles larger in HD?
The pharmacological efficacy of serotonergic-acting drugs suggest that patients with obsessive–compulsive disorder (OCD) may have alterations in their cerebral serotonergic (5-HT) receptor system, and previous neuroimaging studies of OCD patients have shown abnormalities in several fronto-subcortical regions.
In this study we investigated cerebral 5-HT2A receptor binding in 15 untreated OCD patients and in 15 age- and gender-matched healthy volunteers by magnetic resonance imaging and [18F]altanserin positron emission tomography (PET). Eleven of the patients were rescanned with PET after receiving treatment with a selective serotonin reuptake inhibitor (SSRI). The distribution volumes of specific tracer binding (DV3′) were calculated for 12 brain regions, and comparisons were made between: (1) healthy volunteers vs. untreated OCD patients, (2) healthy volunteers vs. treated OCD patients, and (3) OCD patients before and during treatment.
When comparing the distribution volume for specific fronto-subcortical brain regions, significantly higher values were recorded in the caudate nuclei in OCD patients (DV3′: 0.24±0.14) compared to the healthy control group (DV3′: 0.15±0.13) (p<0.05, Wilcoxon matched-pairs test). This difference between groups was not present after treatment with SSRIs. There was no correlation between the severity of OCD symptoms and 5-HT2A receptor binding. An increase in 5-HT2A receptor binding is found in the caudate nuclei of untreated patients with OCD. The up-regulation in 5-HT2A receptors might be compensatory for a lack of serotonin in the feedback loop between the thalamus and orbito-frontal cortex, the caudate nuclei, and the globus pallidus.
I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.
Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.
On a recent PodcastUFO episode with Martin Willis, ex-CIA officer John Ramirez described a symposium that he was invited to by a colleague where government officials and members of the Invisible College were given a presentation on the hybridization of the human genome by non-human beings.
>It wasn’t a conference, it was more of a one day symposium at a hotel. It was unclassified. It was hard for me to believe it was unclassified and I was able to enter, as I stated, with my cell phone, no ID whatsoever, no badges, completely open inside this conference room. It was not a SCIF.
>And to hear what I heard, I said “okay, there’s something to this story.” They relayed it to the fact that it went back to after World War II, for this hybrid story. They didn’t present any evidence. So when they say I don’t have evidence, I agree with you. I don’t have any evidence. All I have is these two top officials saying that the CIA has been interested in the hybridization of humans and have discovered alien DNA in the human genome. That’s what they told me.
>So if I get permission to use their names — they’re still alive — if I get permission to use their names then that offers another avenue for researchers to actually knock on their doors and ring their phones and say “hey, where’s the evidence? How do you know this yourself, that they told me and others in that room about alien DNA?”
>So that’s where I’m at right now. In conjunction with that, I wanted to get my medical records from the CIA. That’s a separate process, it’s not a FOIA process for employees, or former employees of the CIA. We go through different internal channels where we can self-identify as CIA officers because I have a secret number, as I’ve said it’s not 007, but there is a number that they can look up and actually say “yeah, this guy is CIA.”
>So I requested my medical records. I’m still waiting on them. They’ve acknowledged receiving my request, and I’m just still waiting on them to deliver, to me, my medical records. I want to see what my medical records might say about any high strangeness the CIA found.
Martin mentions people get hung up on John talking about the hybrid story, and asks him to clear up whether hybridization started happening in the 1940’s forward or if that’s when they discovered something.
>That’s when the government discovered that the human genome contained alien DNA.
Martin then asks how would we know it was alie
... keep reading on reddit ➡This whole interview with Dr. Garry Nolan is absolutely mind blowing.
If these comments from an award-winning Stanford geneticist don’t make skeptics reconsider the “woo” aspect of the phenomenon, I don’t know what will.
>Nolan: From my point of view, when I got involved, the CIA came to my office. I mean at first I thought it was joke. I really did. I was looking across the way here at some of the other offices to see if there was a camera. So they said. “We asked around, and everybody said that you’ve built the best tool, called CyTOF.”
>I was introduced to others who were, I think you people call them the Invisible College. It was people like Jacques, people like Hal Puthoff, Eric Davis, and Robert Bigelow and Colm Kelleher. Then they showed me MRIs of some of these people and most of those people had interactions with UFOs. These were Department of Defense and intelligence people, so supposedly and reasonably credible individuals.
>So in looking at the MRIs of some of these people, we noticed an area of the brain that seemed to be disturbed, let’s say, or different in many of these individuals. So it’s an area that I’ve talked about before between the head of the caudate and putamen that had increased neural density. It was larger in all these individuals.
>So you just ask the question, “Okay, what’s unique about these individuals?” Well, they’re all highly functioning and have to make snap decisions, and so what is that? That’s intuition. One way to explain it would be intuition, or just highly intelligent.
>Then, surprisingly, when we looked into the family members, we found that the family members had it, which was fascinating. So that means that structure had a genetic component, whatever it was.
>Michels: Here’s a question. Do you have a genetic and phenotypic predisposition to seeing the UFOs or, post-contact, do you now have a more neuronally dense caudate nucleus and putamen?
>Nolan: No, I don’t think it’s changed. They’re just able to, as you say, see it. They’re able to recognize it for what it might be and not dismiss it.
>Michels: Maybe it’s allowing us to kind of widen the doors of our normal limited scope of perception. You’re seeing these UFOs that exist kind of interstitially in reality that other people just can’t see.
>Nolan: Our senses are a filter to stop our brains from being overwhelmed with reality. So what we see is a
... keep reading on reddit ➡I was reading this article about the Stanford scientist studying UAP materials and really enjoyed the straight to the point perspectives by the professor.
However while reading it, he mentioned a certain Dr. Kit Green, and Vice links to this article. I am not a believer of what theSun posts but what gave this some credence for me:
- The Stanford Professor Garry Nolan mentions Dr. Kit Green -- he was contracted by the DoD/Pentagon or a faction within it to study people who had come to contact with UAPs.
- Vice links this particular article; there can be a few reasons:
- This is the most apprehensive article on the subject of Dr. Kit Green + the memo + video , all in one -- so it made it easier for the writer to show everything with one link
- I am guessing Vice interviewer checked with Professor Nolan and he said yes that summarizes well
- I don't know, the above two bullet points can be wrong, but I am taking the Vice article as well written, the Professor credulous, hence the Sun link = less salt
I read the article and in it there is a mention of the memo, the Sun article has two pages of it, but here is the full one.
- It's basically a summary of points by Dr. Kit Green from Eric Davis to Bigelow and cced Colm Kelleher (Colm is mentioned in the Vice article) + emails
- The summary goes deep into the professional thoughts of Dr. Kit Green re: the alien autopsy video
- Here is a link to the full autopsy video, I am sure all of you have seen this
- I had seen this as well and in my mind always dismissed it as fake, but never watched it to the end, where there are ibeams shown as well, which is crazy cool
- Basically Dr. Kit Green says that the video is legit
- You will find lots of debunking of it, but it seems it was done after the fact and the original guy that released it, Santilli, just stopped giving a two after years of harassment and went silent.
I also researched the areas that Dr. Green mentioned were missing in the brain, or different from human anatomy:
- No Corpus Callosum -- This is an area that connects the two hemispheres of the brain. Lack of this in humans is known as **
Can anyone refer to any reviews or studies that have attempted to differentiate the nuclei of the caudate nucleus and the putamen in the dorsal striatum? I'm trying to get a better idea of how the basal ganglia works and most of what I've read seems to lump the two together.
I just heard about this theory recently, but I can’t find any credible studies about this subject. Wondering what this thread thinks
Do your worst!
Hello, hello!
This is it, the last day of the year.
Time to issue your predictions for the year 2022.
You may use any method of divination for this, as well as argue rationally for the most likely outcomes. With that said, with high risk comes high reward, and bold predictions will of course see you revered as a psychic or a prophet.
Rules:
- You must limit your predictions to events that will occur between Jan 1st and Dec 31st, 2022
- The predictions must be related to UFOs and occult phenomena, or personalities in ufology
- Be nice -- avoid joking about death/disease/dismemberment/etc.; treat sensitive subjects with respect
This thread will remain open for submissions until January 7th and will be revisited at the end of the year!
There are no prizes, other than finding out if you're psychic.
So flex that very fibrous caudate-putamen complex, and show us what you got!
EDIT: Post locked!
I'm surprised it hasn't decade.
For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.
I said "hey look, an escaPEA"
No one near me but it didn't half make me laugh for a good hour or so!
Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies 😂
It really does, I swear!
I just finished reading the book American Cosmic by Diana Pasulka, and one of the main scientists she engages with is given the pseudonym “James.”
She writes about a presentation James gave to a group of academics about human predisposition to having UFO experiences.
>Like a gust of fresh air, James’s opening statements completely and unequivocally transcended our stoic provincialism. As we examined his pictures of the microscope and sipped our coffee, he blindsided us with this assertion: “We will start by stating that the phenomenon commonly referred to as UFOs exists. The evidence supports that there is a phenomenon, it interacts with humans, but we cannot as yet explain it. However, we can identify its effects on humans and the physical channels of communications through which it operates. Through studying its modes of interaction with us, we can gain considerable knowledge about it.”
>This claim caused the hairs on our well-trained academic necks to rise. We were now wide awake—and not because of the coffee.
>To scientifically capture all these experiences or events, argued James, the people predisposed to having them—that is, to being contacted by nonhuman intelligence—must be studied. The literature shows that contact manifests as anomalous experiences, as telepathic communication with aerial objects and beings, or as anomalous cognition (knowledge of future events or other knowledge for which there is no conventional explanation). It also manifests as random sightings of aerial phenomena that sometimes interact with witnesses through such things as “beams of light.” The Bible and records from Catholic history and other religious histories are replete with accounts of such events. James’s own experiences and those he had recently learned about from his relatives informed his theory, but he had also studied others who reported them. As a scientist, he was aware of two things, one explainable, the other not. His research found that some people exhibited knowledge of events for which they should not, according to what we know about normal processes of acquiring information. He could not explain this, but he relied on quantum theory to suggest that particles distant from each other seem to have knowledge of each other and even affect each other (“spooky action at a distance”). And scientists don’t know why this is so. He suggested that perhaps there is a quantum field of information and somehow his subjects tap into it. He theorized that
... keep reading on reddit ➡The Mind Sublime (the guy who discovered the original AATIP slides on Chris Mellon's website) made an excellent/interesting post on his blog awhile back.
https://mindsublime.blogspot.com/2020/05/extrasensory-perception-and-caudate.html?m=1
If you'ld rather listen then read the blog article, here's a link to the audio from The Mind Sublime's youtube channel:
https://youtu.be/6xoydlEXbhE
It's about a book recommendation that was made to him by Garry Nolan of Stanford's Nolan Lab who does combined work with Kit Green, working with people who have been affected biologically from "close encounters with anomolous craft" and Jacque Vallee on spectroscopy tests on purported debris of UAP. The book recommendation was Through the Curtain and it's about extrasensory perception, including remote viewing and remote information downloading, which has a strong foothold in the lore of the ufo phenomena, and it's link to a part of the brain called the Basal Ganglia made up of the Caudate Nucleus and the Putamen. I felt that if Garry Nolan, with his connections to Kit Green/Vallee who has further connections with Hal Puthoff/Eric Davis (basically the core of the Invisible College) is recommending a book about the topic it's probably worth the read so I wanted to post it here.
Here's a link to a pdf of the book:
https://u1lib.org/book/5233506/00d339
Additionally, here's a pdf of a paper that Kit Green and Garry Nolan worked on studying people who have been affected by close encounters of ufos. It's not super in depth but it holds water as proof of the governments interest of physical effects of close encounters:
https://warpdrivecar.files.wordpress.com/2020/02/medicalreport.pdf
The blog post/video goes into more depth about Garry Nolan/the Caudate Nucleus/Extrasensory perception, and if anyone has any interesting leads related please do post. With the American Alchemy interview with Garry Nolan blowing up on here the past few days, I figured this would be an interesting read/rabbit hole for folks.
Edit: A commenter posted saying the link to Nolan/Green's medical paper pdf on close encounters wasn't working. If that link doesn't work for an automatic download, here's a link that will open it in a browser tab:
https://fdocuments.in/reader/full/clinical-medical-acute-subacute-field-effects-on-human-2020-02-16-clinical
Thoughts around the caudate nucleus & its potential for granting ESP-like functions. How it was predicted by a psychic in the 60s and how mainstream science accepts the the caudate-putamens' purpose for "intuition".
Do we have unrecognised "psychic" potential for anomalous information receipt?
https://mindsublime.blogspot.com/2020/05/extrasensory-perception-and-caudate.html?m=1
The 3D reconstruction shows that caudate nucleus crosses ventricles at the top. When I checked the source MRI (see below) something like that can been seen indeed unless I'm misinterpreting it. I'm wondering now, is that normal that CN expands above the lateral ventricles or more like an anomaly?
The MRI is of a 6yo child.
https://preview.redd.it/07ou1ymstiv31.png?width=3126&format=png&auto=webp&s=d123fa4a0859e8b5e654da0cb962a57996799f30
https://preview.redd.it/4dqu7zmstiv31.png?width=3538&format=png&auto=webp&s=e550ce89a49e37581f55d79ab9db2b21b04e14eb
Buenosdillas
They’re on standbi
Pilot on me!!
Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.
This sub is mostly just NSFW puns now.
If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.
Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.
When I got home, they were still there.
What did 0 say to 8 ?
" Nice Belt "
So What did 3 say to 8 ?
" Hey, you two stop making out "
I won't be doing that today!
