Atopy

I’m not sure if this is going to be considered too long. I just need someone to talk to. Even if I’m simply screaming into the void, I need to get this out of me. It might seem like whining. Maybe it is. Maybe I should pull myself up by my bootstraps… I. Simply. Do. Not. Have. The. Energy.

I recently stumbled upon a word while reading that resonated with me. It’s from the Greek, “Atopy” - placelessness, outside

I cannot tell if people seem unreal to me or if people seem too real to me—my senses are on fire. What I do know is that I cannot find my place amongst them. I’ve never been able to.

There are days—like today—where I want to quit my job and the world. I just simply never want to leave my property ever again. The thing is, I think I could do it and not feel like I missed a thing. Maybe. Mostly. There is a residue of a desire for connection. I wish there wasn’t.

I recently discovered, during a neuropsychological exam that led to my Autism Spectrum Disorder diagnosis, that I have an IQ higher than 90% of the people my age. Yet, I’m barely able to function working part-time as a janitor at a museum. I’ve done the math. For every 1 hour of “normal” neurotypical-like behavior I need 7 hours to recuperate. And that’s not just a simple day off, it’s a day of limited movement in a dark, cool, and quiet room.

There’s 168 hours in a week. That’s not a lot of time for “normal”. There are moments when it’s difficult not to resent the world. A world designed for brains different than mine.

At times, I feel like a saltwater fish expected to adapt to a freshwater world. The neuropsychologist called me “twice-exceptional”. I have exceptional cognitive abilities and exceptional deficits in other major areas of my life. Yay.

I guess what got to me today is the realization that I will always be on the outside amongst neurotypical people. Hell, I feel on the outside amongst neurodivergent people. That’s how it’s always been… but my ASD diagnosis was only a month or so ago. I used to think if I just tried to be like “normal people” a little harder… well that never worked. And now I know why. Now I know it can never work.

It’s just hard seeing coworkers, who have started after me, bond so easily with existing staff. I hear them and see them talking and laughing… I just don’t know how to relate. It’s like I process what people are saying 75% slower than everyone else. I cannot maintain eye contact, it’s actually distressing. I don’t know how to navigate the

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📅︎ Aug 13 2021
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DAE have "atopy" (allergy/eczema/asthma) and feel like their immune system reacts "too strongly"?

Newly diagnosed, and also recently had a sepsis reaction to a skin infection that, for most people, is self limiting to the skin. I've always felt like I got sick more than most people, and I've dealt with allergies (pollen / airborne) and eczema my whole life (was diagnosed with asthma as an adult, though given an advair inhaler as a child). My blood work/tests have pretty much always been normal (besides briefly being prediabetic) / not indicative of any particular reason for this. I have sensitive skin (was getting chronic hives randomly for about a year with no known cause and my skin reacted negatively to masking) as well on top of eczema.

I know fibro makes you more sensitive to PAIN , but does anyone else feel their body is just more hypersensitive or "delicate" overall?

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📅︎ Jun 19 2021
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The composition of a newborn’s first stool can reveal whether they are likely to develop allergies within their first year of life, according to a new study in Cell Rep. Med. Babies who developed allergic sensitization – also known as atopy – by the age of 1 year had a less diverse gut metabolome. technologynetworks.com/im…
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👤︎ u/LMasonSci
📅︎ Apr 29 2021
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Atopy?

Has anybody seen, read, found any articles that indicate that people with atopy (16% of the Northern European population) should NOT be vaccinated? Please cite.

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📅︎ Feb 26 2021
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High levels of butyrate and propionate in early life are associated with protection against atopy

"Children with the highest levels of butyrate and propionate (≥95th percentile) in feces at the age of one year ... were less likely to have asthma between 3 and 6 years."

"Children with the highest levels of butyrate were also less likely to have a reported diagnosis of food allergy or allergic rhinitis. "

"Oral administration of SCFAs to mice significantly reduced the severity of allergic airway inflammation."

https://onlinelibrary.wiley.com/doi/full/10.1111/all.13660

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📅︎ Oct 29 2020
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23M CHRONIC itchiness, tension and restlessness from eczema, rhinitus and high IgE levels (atopy)

Hi and thanks in advance for reading/votinf/responding!

23M otherwise fit and healthy, suffering from atopic eczema, rhinitus and mild asthma since birth (the doctors noticed redness around my face and joints and suggested I likely have allergies).

As is common, my health has significantly improved into adolescene and over the past few months I have grown and healed a lot.

While my symptoms have definitely improved, I am experiencing a sense of disillusionment as I realise how the symptoms are STILL painful.

So my question is: what is the most effective treatment to reduce or eliminate the symptoms of itchiness, tension and restlessness from my condition.

I have had my adenoids/pollups removed and my septum aligned. I moisturise every day. I take my have my asthma inhaler and sinus sprays if I meed them and I have done drops under the tongue for immunotherapy for years (and will do the injections when I can afford it). I avoid allergens as much as practicable, especially the ones I am most sensitive to (I don't eat shellfish and am very cautious dust and mould). I even spray my (very clean) carpet with a eucalyptus concentrate to kill the dust mites. I have been seeing a new doctor recently who put me onto bleach baths and sinus rinses which have been incredibly effective. I have even been doing the wim hof method with cold showers (I had an ice bath yesterday!) and breathing exercises, as well as meditation/yoga and trying other natural remedies such as a lavender and manuka honey exfoliant bar. I eat, sleep and exercise like a healthy human and am generally happy.

The problem is that I can't focus at university. Iv'e been failing subjects and felt really anxious/depressed/stressed for a while there. I am just constantly itchy and my breathing is always disrupted. As a result I'm fatigued, have tense and sore muscles and can't sit still, let alone focus on engineering assessments!

Since seeing my doctor I have been given accessibility provisions so I basicslly get extensions on my assignments.

My symptoms persist, although less intensely, while my treatment is ongoing. The thing is that apart from the bleach baths (with coconut oil and salt by the way) and the sinus rinse (with reconstituion salt, a mild steroid and sometimes an anti-bacterial), I am trying LOTS of supplimentary treatment. E.g. dissolved oxygen in water, bio magnesium, multi vitamins, pro-biotics, beta alanine (I dissolve it in my water during a heavy weightlifting session) and ev

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📅︎ Jan 30 2020
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eNose breath prints as a surrogate biomarker for classifying patients with asthma by atopy. - Abstract europepmc.org/article/MED…
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👤︎ u/ZFekete
📅︎ Oct 23 2020
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Atopy diagnosis

My dog Jax (GSD mix M 3.75 y.o.) has been suffering for a while from itchy paws, which cause him to bite at and chew on them. We have spoken to our vet about this on several occasions, with the suggestion of avoiding chicken and giving him Hydroxyzine when he's very itchy.

Last week he was limping & saw that he had an abrasion on his paw (like it was skinned) so we put him in an e-collar and started using Vetericyn (topical anti-microbial) on his hurt paw. He seemed better about 4-5 days later (yesterday) so we gave him his freedom & ended up going on a walk later in the day.

Today I woke up and he can't put weight on his paw. I called off work and tried to get in to see our regular vet, but they were full so I ended up going to see a different vet at an Animal Hospital. He immediately knew exactly what was going on with Jax and told me that he has Atopic Dermatitis due to inhaled allergens. He put Jax on a long course of antibiotics, gave him a cortisone shot, and put him on Prednisone. He suggested that when the ten days on antibiotics are up I fill another script & just keep going.

I am so grateful that this doctor actually put a name to what's going on. We had been treating this topically and he told me how deep the affected area was & it makes so much more sense why we weren't seeing results. I honestly don't know that we will be returning to our regular vet, I don't feel like they took my dog's suffering seriously.

We ordered Zesty Paws pure wild Alaskan salmon oil & plan on mixing that into his food, and I've even tried giving him local, raw honey to ease the symptoms. Does anyone have any suggestions before we move to Apoquel, or start saving to see a Veterinary Dermatologist? Any experience with this in your pups?

Edited to correct spelling errors

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👤︎ u/bekahed979
📅︎ Aug 06 2020
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ELI5 - What is the difference between allergy and atopy?
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👤︎ u/hapynez
📅︎ Aug 19 2019
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Help: My boyfriend's dog has allergies/atopy. Vet recommended we bathe him 1-2 times a week but I have no idea how to do it.

Hey guys, I'm hoping to get some solid advice on how to take care of this dog who's got major allergies. Poor guy already has lick granuloma on his back paws and a staph infection because of it. I took him to the vet 4 days ago where he was prescribed antibiotics for the infection and antihistamines for his allergies, but the vet also told me that the dog should be bathed at least once a week.

Unfortunately my boyfriend and I live in a trailer and our shower isn't big enough to bathe the dog in. The dog, Twist, is also pretty afraid of bathes and wouldn't get in a tub if we bought one and put it outside.

Is our only option to take him to a groomer? Weekly visits would add up quickly for us and we can't afford that right now. I really want to get this dog happy and feeling comfortable again but I don't know what to do. Any advice would be really greatly appreciated. Thank you for reading.

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👤︎ u/ass_cramps
📅︎ Nov 24 2019
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Fish oil supplementation in pregnancy modifies neonatal allergen-specific immune responses and clinical outcomes in infants at high risk of atopy: a randomized, controlled trial - PubMed ncbi.nlm.nih.gov/pubmed/1…
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👤︎ u/ZCKaiju
📅︎ Feb 09 2020
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Are Mixa Panthenol Comfort and Mixa Atopiance same product?

Hello, in my country I can only find Mixa Atopiance and I'm not sure if they are the same product. What do you think about it/them? Would you recommend it?

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📅︎ Oct 15 2021
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Loss of the interleukin-6 receptor causes immunodeficiency, atopy, and abnormal inflammatory responses jem.rupress.org/content/e…
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👤︎ u/burtzev
📅︎ Jun 27 2019
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Is Atopy more common in Korea than other countries?

I'm legitimately curious. When I lives in the USA, I rarely saw someone with this kind of condition. Now that I'm teaching in Korea, and have taught at several schools over my time here, I usually see a few students per school that have it.

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📅︎ Apr 25 2018
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Gut microbiota from infant with Cow's Milk Allergy promotes clinical and immune features of atopy in a murine model (Mar 2019) onlinelibrary.wiley.com/d…
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📅︎ Mar 24 2019
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Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA ncbi.nlm.nih.gov/pmc/arti…
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👤︎ u/joecam
📅︎ Mar 29 2017
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Population based study: atopy and autoimmune diseases are associated with functional dyspepsia and irritable bowel syndrome, independent of psychological distress

Source: https://onlinelibrary.wiley.com/doi/10.1111/apt.15120

Summary

Background

The pathogenesis of functional GI disorders (FGIDs) is uncertain. However, underlying immune activation and psychological distress has been documented in irritable bowel syndrome (IBS) and functional dyspepsia (FD). Epidemiological data from the UK suggest that FGIDs are linked to atopy and certain autoimmune diseases but this has not been confirmed.

Aim

To test if allergic or autoimmune diseases are independently associated with FGIDs, irrespective of psychological distress in a large population based study.

Methods

A total of 3542 people (mean age 57.9 years and 52.7% females) randomly selected from the Australian population, returned a mail survey (response rate = 43%). The survey asked about a physician diagnosis of autoimmune disease (scleroderma, psoriasis, rheumatoid arthritis and diabetes mellitus) or allergic conditions (asthma, food, pollen and/or animal allergy). The questionnaire assessed psychological distress and Rome III criteria for FD and IBS.

Results

Asthma, food, pollen and animal allergies, psoriasis and rheumatoid arthritis were univariately significantly associated with IBS and FD. Food allergy (OR = 1.66; 95% CI = 1.15‐2.40, P = 0.007), psoriasis (OR = 1.81; 95% CI = 1.19‐2.74, P = 0.006) and rheumatoid arthritis (OR = 1.68; 95% CI = 1.15‐2.4, P = 0.007) were independent risk factors for IBS, controlling for age, gender and psychological distress. In FD, asthma (OR = 1.32; 95% CI = 1.04‐1.68, P = 0.025) and food allergy (OR = 1.78; 95% CI = 1.28‐2.49, P = 0.001) were independent predictors, controlling for age, sex and psychological distress.

Conclusions

There is evidence that both atopic and autoimmune diseases are risk factors for FGIDs, independent of psychological distress, differing in IBS and FD. This provides evidence that different peripheral pathways may be involved in the pathogenesis of certain FGIDs.

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📅︎ Sep 25 2019
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Castle Atopie, the last foothold
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👤︎ u/Azrael707
📅︎ Nov 09 2021
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5 month hx - initially thought = tinea corporis treated with clotrimazole 1%, then pityriasis rosea but persisted, then treated as eczema with dermol wash, ointment and tacrolimus. Sporadic new patches all over body. History of atopy, daily fexofenadine 180mg. Any diagnoses appreciated.
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👤︎ u/Umali95
📅︎ Nov 17 2018
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Helminths are positively associated with atopy and wheeze in Ugandan fishing communities: results from a cross-sectional survey – E. L. Webb – Allergy onlinelibrary.wiley.com/d…
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📅︎ May 22 2016
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Neonatal gut microbiota associates with childhood multisensitized atopy and T cell differentiation : Nature Medicine : Nature Research nature.com/nm/journal/vao…
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👤︎ u/carlsonbjj
📅︎ Sep 12 2016
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Type 1: Plain old allergy (asthma, anaphylaxis, atopy) Type 2: Antibody-dependent, cytotoxic (think
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📅︎ Jun 29 2018
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Could I do electrolysis if I have chronic atopy/a very dry and very sensitive skin?

Do electrolysis work on a skin that is very dry and very sensitive? I suffer from an "atopic syndrome" making my skin very delicate and dry. Of course, I can use some cream and some lotion to reinforce my skin. But I would never have a "normal" skin and stopping them would make my skin very dry and sensitive again. Even if I usually have a (really) clear skin, I am more susceptible to have eczema "for nothing" than other poeple.

When I normally shave without using any sort of lotion, I have red marks on my skin that takes at least 1 day to disappear. Because I have light facial hair and that electrolysis is the only way to go, I am really afraid that it would cause me permanent scars. If it isn't possible then, well, I will definitely give up everything.

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👤︎ u/_Shaana_
📅︎ Jul 08 2016
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📅︎ Apr 07 2010
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