Allele Frequencies Puns

A list of puns related to "Allele Frequencies"

Everything wrong with armchair genetics: Copy/pastes definition of allele frequency, misunderstands it, and in the very next paragraph fails to understand the difference between phenotype frequency and allele frequency
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👤︎ u/Haurvakhshathra
📅︎ Nov 19 2021
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"The Genetic Architecture of Obsessive-Compulsive Disorder: Contribution of Liability to OCD From Alleles Across the Frequency Spectrum", Mahjani et al 2021 ajp.psychiatryonline.org/…
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👤︎ u/gwern
📅︎ Nov 21 2021
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given an allele frequency how many ppl would have at least one copy?

This actually isn't a homework question, I need it for my job lol.

I have a gene that deleted with an allele frequency of 3%. Assuming Hardy Weinberg, I want to know how many out 1000 people would have at least one deleted allele.

This is what I try:

p^2 + 2pq + q^2 = 1000

p^2 + 2(.03)(.03) + .03^2 = 1000

p^2 = 1000 - 2(.03)(.03) + .03^2

I seriously have no idea :(, any help is appreciated.

Intuitively it seems like the number of ppl would be ~6% of 1000, but im not sure

(2 * .03) * 1000 + (.03 * .03 * 1000) ?

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👤︎ u/python_noob_001
📅︎ Nov 05 2021
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An introduction to calculating allele, genotype, and phenotype frequencies (under Hardy-Weinberg and non Hardy-Weinberg conditions). This is a standard topic in genetics and evolutionary biology courses. Video has an overview and then shows 3 examples. youtu.be/XBv9KrIDeeA
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👤︎ u/pleiotropycompany
📅︎ Nov 08 2021
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A broad geographic distribution map of -13910*T allele frequency in south Asia. It is responsible for lactose tolerance.
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👤︎ u/ether_47
📅︎ Sep 22 2021
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Major sex differences in allele frequencies for X chromosome variants in the 1000 Genomes Project data biorxiv.org/cgi/content/s…
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👤︎ u/sburgess86
📅︎ Oct 29 2021
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Does anybody get the question about dominant allele frequency for high/low-elevation birds?

Like wtf? The whole problem didn’t even have a number that’s related to allele frequency.

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👤︎ u/bumbl3b33123
📅︎ May 27 2021
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"Partitioning gene-level contributions to complex-trait heritability by allele frequency identifies disease-relevant genes", Burch et al 2021 biorxiv.org/content/10.11…
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👤︎ u/gwern
📅︎ Aug 19 2021
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Mice carrying the humanized Foxp2 allele were using higher frequencies and more complex syllable types than mice of the corresponding wildtype inbred strain bipartisanalliance.com/20…
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👤︎ u/jordiwmata
📅︎ Aug 03 2021
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How to get bloodtype frequency from limited allele frequency?
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👤︎ u/tony9959
📅︎ Aug 07 2021
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Can organisms with two different allele frequencies mate?

In particular I am referring to the apple maggot fly and its original, still-extant ancestors that only feed on hawthorns.

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👤︎ u/bruhiminsane
📅︎ May 02 2021
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Observed significant increases in frequencies of alleles of more body fat in females contradicts hypotheses that sex differences have adaptively decreased following subsistence transitions from hunting & gather'g to agric bipartisanalliance.com/20…
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👤︎ u/jordiwmata
📅︎ Jun 04 2021
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Why is GG a1298c so rare at only 0.00710% frequency in the population? Does this allele type have any different implications compared to other the alleles homozygous mutations?
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👤︎ u/irinseit
📅︎ Apr 06 2021
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"Identifying loci with different allele frequencies among cases of eight psychiatric disorders using CC-GWAS", Peyrot & Price 2020 biorxiv.org/content/10.11…
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👤︎ u/gwern
📅︎ Mar 08 2021
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eli5 Forensics: why do we need equal distribution of allele frequencies?

Can someone explain why there needs to be a roughly equal distribution of allele frequencies when looking at DNA for forensics and paternity cases?

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👤︎ u/SleepWitch8
📅︎ Feb 21 2021
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Ethnic differences in alpha‐1 antitrypsin deficiency allele frequencies may partially explain national differences in COVID‐19 fatality rates faseb.onlinelibrary.wiley…
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👤︎ u/varoidd
📅︎ Sep 25 2020
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What allele frequency is changing fastest in the human population?

Just curious as to whether we are able to measure this at a meaningful rate, and if so, which is changing fastest.

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👤︎ u/Deathsmith8
📅︎ May 18 2015
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Evolution is the change in the frequency of alleles over generations which means the holocaust was technically evolution sense it changed the frequency of alleles in the German population (I’m not defending the holocaust btw)

Not defending the holocaust btw just saying

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👤︎ u/Send-me-hot-nudes
📅︎ Jul 27 2020
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How to create my own in house allele frequency database (like gnomAD)

Hi everyone! Basically I have 40 whole genome sequences and I want to come up with a way that I can calculate the allele frequencies of the variants within these individuals within this small cohort. Of course I can look in gnomAD to check allele frequency of the variants on a broader scale but I want the allele frequency to be specific to my small cohort and it’s unique genetic architecture.

I am quite new to bioinformatics so sorry if I don’t understand some of the concepts. As an end result I would like to create a site like gnomAD but just for mine (and my labs) use so that going forward if we identify a new variant we can check the allele frequency in our specific country (our country does not have a public genomics database like gnomAD).

I know 40 whole genomes is a very small number but it’s just a starting point and the hope is that we can increase the numbers in the future.

Any help/starting points would be hugely appreciated.

Thanks!

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👤︎ u/iloveparmaham
📅︎ Apr 10 2020
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A variant-centric perspective on geographic patterns of human allele frequency variation elifesciences.org/article…
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👤︎ u/Jamescao_95
📅︎ Dec 28 2020
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Changes in Allele Frequencies at Storage Protein Loci of Winter Common Wheat under Climate Change link.springer.com/article…
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👤︎ u/CytologyGenetics
📅︎ Oct 29 2020
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How to interpret my results - SMA - I see that risk is G allele. In my report I am TT. is that the same as GG? It says magnitude 1 and no frequency numbers. It’s in the grey.
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👤︎ u/JulzGulz85
📅︎ Nov 25 2019
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Allele frequencies in tumour cells

Can allele frequencies within tumour cells tell you whether specific variants are germline or somatic?

I have a tumour sample with an allele frequency 90%. Could that mean that the variant is only somatic, since if it was germline it'd be 100%?

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👤︎ u/jesuislight
📅︎ Feb 19 2020
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HLA alleles frequencies and susceptibility to COVID‐19 in a group of 99 Italian patients onlinelibrary.wiley.com/d…
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👤︎ u/bustead
📅︎ Aug 25 2020
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"Estimating the genome-wide contribution of selection to temporal allele frequency change", Buffalo & Coop 2020 pnas.org/content/early/20…
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👤︎ u/gwern
📅︎ Aug 14 2020
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Population migration and the variation of dopamine D4 receptor (DRD4) allele frequencies around the globe escholarship.org/content/…
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👤︎ u/MakeTotalDestr0i
📅︎ Apr 23 2020
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