One month post hemi and my 27th birthday! Little nerve pain and trouble swallowing as my tumour had infiltrated my neck muscle. Hoping the lesion to my left/remaining lobe hasn’t grown @3 month check up.
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πŸ‘€︎ u/indirosie
πŸ“…︎ Jan 25 2022
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Two things, 1. The vagina is made of highly elastic tissue,supported by a series of mostly horizontal muscles in the pelvic floor 2. The penis is made from Erectile Tissues and is composed of elastic fibers, collagen fibers, smooth muscles, arteries and veins therefore, they're not the same reddit.com/gallery/sazw5s
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πŸ‘€︎ u/Princess_kitty14
πŸ“…︎ Jan 23 2022
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TIL that in 1989 Botox was initially approved to treat two major eye-muscle disorders such as blepharospasm (uncontrollable blinking) and strabismus (crossed eyes) Later in 2002, the FDA endorsed use of Botox to temporarily smooth frown lines between the eyebrows. cidrap.umn.edu/news-persp…
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πŸ‘€︎ u/Angelinapatina
πŸ“…︎ Jan 22 2022
🚨︎ report
whats the name of my condition? I have bump of muscle (not a tumour) around my left knee, if i stand for too long it hurts, i can't bend my leg and walk.

i got checked when i was kid but completely forgot about, now that i work fully time and i am on my feet all day, i need to get this fixed asap cuz it too painfull to stand.

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πŸ“…︎ Jul 03 2021
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WYR Have an inoperable tumour which is painless but you die in 3-6 months or have severe muscle pain which is untreatable but you live out the rest of your life?
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πŸ‘€︎ u/Persian_Sexaholic
πŸ“…︎ May 30 2021
🚨︎ report
How does nitric oxide induce vasodilation in smooth muscles? Is it through upregulation of CGMP to breakdown calcium , or dephosphorylation?

I'm reading conflicting info

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πŸ“…︎ Dec 27 2021
🚨︎ report
To my knowledge if you have β€œhard flaccid” often times the contraction of smooth muscle will appear as fibrosis on an ultrasound. Is that accurate or false?
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πŸ‘€︎ u/Tillicollapse23
πŸ“…︎ Jan 05 2022
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Why is PDE3 found in vascular smooth muscle and platelets?

Like which molecules do they actually hydrolyse in these places?

Is it still cAMP? How is that relevant to these places?

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πŸ“…︎ Dec 27 2021
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(Uworld Question Id: 20449) Question about smooth muscle contraction

Hi, it's your friendly neighborhood dumbass here asking a question again

This question basically says that hypercalcemia interferes with sodium transport as it competes with the sodium transportor --> inhibits neuronal depolarization --> impaired smooth muscle contraction --> reduced colonic motility (eg constipation)

Now I am confused because I thought calcium = smooth muscle CONTRACTION

According to a SDN thread on a similar topic, it explains that calcium interfering with the voltage-gated sodium channels means a higher action potential threshold, so that results in more smooth muscle relaxation and constipation??

According to BnB, smooth muscle doesn't rely that much on action potential and that calcium + calmodulin activates MLCK which phosphorylates myosin and you get contraction.

Am I misunderstanding something or is there some huge physiology concept that I am missing here? Or is it because the excess calcium has some other effect (neuronal depression) that overrides its usual action??

Any help would be great because I am really dumb

Edit: the SDN thread I read through but am still confused: https://forums.studentdoctor.net/threads/constipation-in-hypercalcemia.647220/

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πŸ‘€︎ u/NightOfVanity
πŸ“…︎ Jan 19 2022
🚨︎ report
Dude literally doesn't know the difference between smooth muscle and skeletal muscle...not to mention connective tissue...thinks he is Albrecht von Haller (father of modern physiology)
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πŸ‘€︎ u/Macha_Grey
πŸ“…︎ Nov 29 2021
🚨︎ report
39, 45 months hrt, & 4.5 months post FFS with Dr Timothy Osborn (type 1 forehead/mandible contouring, jaw muscle reduction, brow lift, lipo under chin, smooth out cleft chin). Still a bit swollen but healing up well!
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πŸ‘€︎ u/uponthesun2005
πŸ“…︎ Oct 23 2021
🚨︎ report
What's the origin of "Smooth Muscle Control"

All I know is that it's a Warlord thing

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πŸ‘€︎ u/PurplePurpura
πŸ“…︎ Nov 01 2021
🚨︎ report
In a significant step forward in regenerative medicine, scientists at Cincinnati Children's report success at developing a stomach organoid so sophisticated that it has distinct glands and nerve cells that can control smooth muscle contractions medicalxpress.com/news/20…
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πŸ‘€︎ u/Dr_Singularity
πŸ“…︎ Dec 10 2021
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Can smooth muscle twitches be related to GERD and air quality? - please help my condition is getting worse....

I have very disturbing symptoms for the last 2 months - it started with little reflux which was felt by me as heartburn and about 3 weeks later - muscle twitches in the legs, chest, arms and neck. These twitches sometimes get stronger very suddently, which makes me scared totally.

However, they only happen inside my home - the less ventilated or heated it is, the worse symptoms.

When i go outside - these twitches slowly go away. I suspect, lower oxygen or less humidity inside my home - but can it trigger smooth muscle twitches? Sometimes i feel only reflux, sometimes only twitches, but the worst is when they both happen at the same time.

Blood tests regarding heart, EKG, Sodium, Potassium, Magnesium, D-Dimer, X-Ray of chest, kidneys are all fine.

ALL doctors told me its 100% anxiety and panic attacks. But, when i dont have these twitches I sleep like a baby, my life is the same as 6 months ago, 1 year ago etc....

I may have ongoing stress from various issues, but I got used to it. Could it be nervous system burn out? I work a lot and have relatively little relaxation.

Can my condition originate from the GERD? When it started I ate a lot of chocolate and citrus fruits, other than that my diet is rather on a healthy side - not too much or too little of all kinds of foods...

I will be grateful for your help.

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πŸ‘€︎ u/QuickThinker1977
πŸ“…︎ Dec 27 2021
🚨︎ report
375 cc Smooth implants… under muscle with placement of mesh.., ok, I’m currently a 38A (small) 5’7” on HRT nearly 11mo. I am 61 so not looking to be huge, but definitely what a large C. Surgery is next week… any advise or comments appreciated πŸ’•
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πŸ‘€︎ u/4dana
πŸ“…︎ Oct 18 2021
🚨︎ report
Josh finally gave in to warlord’s smooth muscle control v.redd.it/ydhxp2d8a4s71
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πŸ‘€︎ u/fishisdairy
πŸ“…︎ Oct 08 2021
🚨︎ report
[Grade 12 A&P] Largest and most complex smooth muscle.

Thanks in advance.

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πŸ‘€︎ u/DescriptionNo1664
πŸ“…︎ Dec 16 2021
🚨︎ report
In a significant step forward in regenerative medicine, scientists at Cincinnati Children's report success at developing a stomach organoid so sophisticated that it has distinct glands and nerve cells that can control smooth muscle contractions medicalxpress.com/news/20…
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πŸ“…︎ Dec 10 2021
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Increasing positive SMA (smooth muscle antibodies)

Hello! 28 F here. Just reaching out for advice or any knowledge as I have some health anxiety. I had a weak positive for smooth muscle antibody (SMA) back in early July (titer of 1:40). Was also diagnosed with fatty liver and a gallstone that grew to 2.3 cm (via sonogram) and had liver enzymes of ALT 41 and AST 28. I was just retested last week and now my smooth muscle antibodies titer has risen to 1:80. ALT is now 31 AST 28. I am worried about autoimmune hepatitis although I have no symptoms and my doctor’s do not seem too worried (although I haven’t been to a hematologist yet). Thanks so much for any info!

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πŸ“…︎ Nov 01 2021
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Could someone clarify how "smooth muscles don't have sacromeres"?

I know it's low yield. I was just hoping to clarify the concept. I thought sarcomeres were just actin and myosin. It looks like smooth muscle contains both actin and myosin. Is there some defining characteristic outside of actin and myosin that is necessary to be defined as a sarcomere?

Thanks in advance!

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πŸ‘€︎ u/472islife
πŸ“…︎ Oct 28 2021
🚨︎ report
Tips to keep muscles "smooth" after stretching?

I notice this especially in my split practice: It seems like every day I'm starting from zero.

Obviously that is not the reality and I do realize how far I've come since actively working on them, but it does seem like it takes an incredible amount of warm up and stretching to get to the point where I can actually work on improving where I was at the day before.

I know every body is different and so is each yoga journey, but I was wondering whether I am doing something wrong? Is there a trick to keep muscles smooth after stretching as to not feel like they are all stiff the next day?

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πŸ‘€︎ u/hardcoverhowl
πŸ“…︎ Oct 03 2021
🚨︎ report
is calcium-induced calcium release seen in Smooth Muscle cells or is it only in Cardiac cells?

Different sources say different things so i was just a bit confused.

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πŸ‘€︎ u/AdSimilar2398
πŸ“…︎ Nov 07 2021
🚨︎ report
Do smooth muscle also have sarcomeres?

So i've read this source, talking about how muscles contract, talking about sarcomeres and actin and myosin and all that jazz, but strangely, it constantly seems to imply that the sarcomere structure and function is exclusive to skeletal muscles, every image is of skeletal, it keeps mentioning skeletals, etc.

So is sarcomere also present in smooth muscles and heart muscles? If not then how do they work, and if yes, why don't smooth muscle cells have the same stripy appearance of skeletal ( and kind of, heart) muscles?

Thanks in advance

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πŸ‘€︎ u/cyan_the_II
πŸ“…︎ Oct 30 2021
🚨︎ report
What does a possitive smooth muscle ab w/refl titer mean?

23 year old hispanic male, currently have nafld, no fibrosis and alt at normal range. I just got my most recent lab results and I saw that my smooth muscle ab screen came out as positive and my smooth muscle ab titer came out as β€œ1:20 H” and I have no idea what those two mean, can someone help me interpret those results? Thanks.

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πŸ‘€︎ u/Dvid_8991
πŸ“…︎ Oct 10 2021
🚨︎ report
Vascular smooth muscle cell

Do both ↑ cGMP and ↑ cAMP cause vascular smooth muscle cell relaxation thus vasodilation? I am wondering that bc nitrates cause vasodilation by increasing cGMP while beta-2 adrenergic receptors cause vasodilation by increasing cAMP.

TIA!!

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πŸ‘€︎ u/thechiguy1
πŸ“…︎ Oct 26 2021
🚨︎ report
Cat fine needle aspirate taken from intestinal mass showed smooth muscle tumor cells?? Anyone have more info on this for research? THANK YOU ALLπŸ’™

OG Post here

Finally received the results of the fine needle aspirate done for an intestinal mass on my kitty!

After an ultrasound, the large mass (5cm) seen on xray was actually on my boys small intestine! Ofcourse myself & the vet go into worst case scenario thinking it's most likely lymphoma or a carcinoma. The ultrasound did not see any inflammation on any lymph nodes so the vet was saying 60/40 it was either a carcinoma v lymphoma. We did a biopsy regardless & it indicated neither cells describing the two above cancers.

Instead it was something my dr described as super rare with very little info on it. The oncologyist believes it is smooth muscle tumor & recommends surgery for removal and maybe chemo after that.

I'm so happy that we have options to treat my best friend. Even if it only gives him a year it's much more time together than the month estimates we were given before. The best news I've received in ages, even in such a terrible situation πŸ’™πŸ’™πŸ’™πŸ’™

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πŸ‘€︎ u/Osari
πŸ“…︎ Sep 29 2021
🚨︎ report
Preventing crosstalk between matrix and vascular smooth muscle cells reduced vascular stiffening by 70% in mice medicalxpress.com/news/20…
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πŸ‘€︎ u/user_--
πŸ“…︎ Aug 26 2021
🚨︎ report
5 badges were collected. Besides losing Muscle to Chuck's Poliwrath, everything goes smooth.
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πŸ‘€︎ u/Morlino
πŸ“…︎ Sep 17 2021
🚨︎ report
Simple ways of sculpting muscle definitions and creating smooth transitions between different shapes youtu.be/yesFet3Iv5Y
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πŸ‘€︎ u/Karajohnis
πŸ“…︎ Sep 05 2021
🚨︎ report
Is this smooth muscle? why is it in the hypodermis of thick skin (orange rectangle) ? reddit.com/gallery/oso14e
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πŸ‘€︎ u/JDR2001
πŸ“…︎ Jul 27 2021
🚨︎ report
Smooth Muscle Disfunction?

My husband and I have recently decided to see a secondary fertility specialist. The first clinic I went to diagnosed me with PCOS, endometriosis (without a laparoscopy) and possible adenomyosis, calcifications and cysts on my ovaries.

We went through 3 rounds of IUI and were told if we want a more successful route to move to IVF. I got a quote for IVF at this clinic and found it was wildly outside of our means.

A friend referred me to a different clinic out of state that is within our financial limits. After meeting with this doctor he’s wanting to see if instead of the laundry list of issues I’ve been told I have, if it’s an issue with the smooth muscle in my body.

Has anyone else dealt with this or been down the route of testing smooth muscle function?

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πŸ‘€︎ u/chelsrawr_00
πŸ“…︎ Sep 27 2021
🚨︎ report
Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women have no symptoms while others may have painful or heavy periods. If large enough, they may push on the bladder causing a frequent need to urinate.... medizzy.com/feed/28705706
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πŸ‘€︎ u/GiorgioMD
πŸ“…︎ Aug 11 2021
🚨︎ report

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