Positive correlation between DNAm clocks and frailty pubmed.ncbi.nlm.nih.gov/3…
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πŸ‘€︎ u/throwawayamd14
πŸ“…︎ Nov 23 2021
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DNAm-based signatures of accelerated aging and mortality in blood are associated with low renal function [2021, open-access] clinicalepigeneticsjourna…
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πŸ“…︎ Jun 08 2021
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Poverty leaves a mark on our genes, suggests a new study, which found that lower socioeconomic status is associated with levels of DNA methylation (DNAm) at more than 2,500 sites, across more than 1,500 genes. In other words, poverty leaves a mark on nearly 10 percent of the genes in the genome. news.northwestern.edu/sto…
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πŸ‘€︎ u/mvea
πŸ“…︎ Apr 06 2019
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COVID-19 Severity is Predicted by Earlier Evidence of Accelerated Aging (DNAm PhenoAge) medrxiv.org/content/10.11…
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πŸ‘€︎ u/StoicOptom
πŸ“…︎ Jul 13 2020
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Dnam πŸ€”πŸ€€πŸ€¬πŸ‘πŸ€¬ DanielπŸ˜‚πŸ€€πŸ‘πŸ€”πŸ€¬
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πŸ‘€︎ u/Hultbrant
πŸ“…︎ Feb 19 2020
🚨︎ report
Poverty leaves a mark on our genes, suggests a new study, which found that lower socioeconomic status is associated with levels of DNA methylation (DNAm) at more than 2,500 sites, across more than 1,500 genes. In other words, poverty leaves a mark on nearly 10 percent of the genes in the genome. news.northwestern.edu/sto…
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πŸ‘€︎ u/jsalsman
πŸ“…︎ Apr 07 2019
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Dnam DanielπŸ‘πŸ€€πŸ€£πŸ€€πŸ€”πŸ€¬
πŸ‘︎ 29
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πŸ‘€︎ u/Hultbrant
πŸ“…︎ Feb 19 2020
🚨︎ report
Poverty leaves a mark on our genes, suggests a new study, which found that lower socioeconomic status is associated with levels of DNA methylation (DNAm) at more than 2,500 sites, across more than 1,500 genes. In other words, poverty leaves a mark on nearly 10 percent of the genes in the genome. news.northwestern.edu/sto…
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πŸ‘€︎ u/Akkeri
πŸ“…︎ Apr 06 2019
🚨︎ report
Poverty leaves a mark on our genes, suggests a new study, which found that lower socioeconomic status is associated with levels of DNA methylation (DNAm) at more than 2,500 sites, across more than 1,500 genes. In other words, poverty leaves a mark on nearly 10 percent of the genes in the genome. news.northwestern.edu/sto…
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πŸ‘€︎ u/MarshallBrain
πŸ“…︎ Apr 07 2019
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Dnam hates me
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πŸ‘€︎ u/Pedroguitrez
πŸ“…︎ May 01 2020
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Using TESVEdit to create a personal patch. I see lots of DNAM objects with conflicts. How can I figure out what these are?

There are 345 of these DNAM objects. Specifically I'm seeing conflicts between Weapons and Armor Fixes and Hothtrooper44_ArmorCompilation.

Any idea which mod has the "correct" settings?

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πŸ‘€︎ u/mydah42
πŸ“…︎ Jan 11 2014
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Dnam it, rules will be implemented soon v.redd.it/3uhvnukh82n01
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πŸ‘€︎ u/Knitler0
πŸ“…︎ Mar 21 2018
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SERIOUS: This subreddit needs to understand what a "dad joke" really means.

I don't want to step on anybody's toes here, but the amount of non-dad jokes here in this subreddit really annoys me. First of all, dad jokes CAN be NSFW, it clearly says so in the sub rules. Secondly, it doesn't automatically make it a dad joke if it's from a conversation between you and your child. Most importantly, the jokes that your CHILDREN tell YOU are not dad jokes. The point of a dad joke is that it's so cheesy only a dad who's trying to be funny would make such a joke. That's it. They are stupid plays on words, lame puns and so on. There has to be a clever pun or wordplay for it to be considered a dad joke.

Again, to all the fellow dads, I apologise if I'm sounding too harsh. But I just needed to get it off my chest.

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πŸ‘€︎ u/anywhereiroa
πŸ“…︎ Jan 15 2022
🚨︎ report
AITA for refusing to eat food I don't like?

I (56M) have a son (28M) who spent a lot of time traveling overseas in his college years. He went all around the world, including several trips to the Middle East, where he studied for his minor in Arabic language and literature.

A few years ago, my son found out that a woman he knew in Pakistan had a son (9M). She claimed this son was his, which I doubted. My son, however, believed her without question. He asked this woman to send her son to the US to stay with my son so they could get to know each other. He has spent the last few summers here.

Recently, the boy moved in with my son fulltime, a decision I strongly urged against. My son enrolled him in the same private school we sent him to at that age, which is very expensive. I have tried to support my son's decision, but it has been hard. I really want my son to get a DNA test, but he stubbornly keeps refusing.

Recently, things came to a head at a family dinner my son invited us to. He said the boy was feeling homesick, so they cooked Pakistani food together. My son wanted the whole family to eat this food, because he said it would make the boy feel like he and his culture were accepted by the whole family.

Now, I don't like Middle Eastern food. I don't like strong spices. My son begged me to just try some of it, or to at least eat the bread they made. The bread had flecks of all kinds of weird spices on it though, so I refused. My son got mad and asked me to please eat something just to "make your grandson happy." He pulled me aside for this, so the boy wasn't present to hear our conversation.

I told my son that I have no proof he is my grandson, and even if I did, I shouldn't have to eat food I don't like. My son called me a selfish, stubborn A and then asked me to leave. So, I did. My wife stayed though.

My wife agrees with me that I shouldn't have to eat food I don't like, but she said I could have at least tried a bite to appease our son. She thinks I was just being stubborn to be stubborn. I wasn't though. I don't like Middle Eastern food, that's all. How can I be the A for that? Still, my son isn't speaking to me right now. Should I have just tried some bread?

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πŸ“…︎ Jan 01 2022
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Blind Girl Here. Give Me Your Best Blind Jokes!

Do your worst!

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πŸ‘€︎ u/Leckzsluthor
πŸ“…︎ Jan 02 2022
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If you’re conventionally attractive, life is automatically 100x easier for you

Go on tiktok right now to see what I mean. Attractive people are being handed million dollar branding deals and getting millions upon millions of followers for literally staring at a camera. Absolutely no talent, skill or personality needed. Even if they do have skills I’m sure having tons of validation and constant support helps you stay motivated. Everyone pretty much knows this but what really bothers me is these people don’t even acknowledge how much it benefits them. They didn’t get these things solely cause they β€œworked hard”, they got it because being physically attractive makes everything easier. When you’re physically attractive you can pretty much do anything and people will forgive you. You can lack integrity, honesty, you can fuck people over, you can be creepy and get away with all of it. Even studies show that attractive people get way less severe punishments for the same crimes. All you have to do if you’re attractive is not murder people and you’re life is pretty much set on easy mode. Making friends and business connections will be a breeze, lame jokes you tell will come off as funnier, any weird or disturbing trait you possess will come off as cute and quirky, people may even give you stuff for free or invite you to exclusive events, simply because you’re attractive. If you’re attractive just know that you have been handed the good life on a golden platter. You can get by with one tenth the effort of the average person and still gain more respect for the same amount of work. The people who will truly understand what I mean are those who went from being conventionally ugly/below average to conventionally attractive… whether it was from puberty, weight loss, surgery, etc. The difference in how people treated you before and after is astounding to say the least. People who are born with it though will never truly understand how it influences almost every aspect of their life.

Edit: Before anyone calls me out on sounding bitter, just know this also comes from my own personal experience from how I was treated before and after puberty and from what I see going on around me as well. What I’m saying is nothing new, we all know this is going on but I feel this is becoming more and more apparent as the world we live in becomes more centered around appearances and garnering attention. I’m not saying attractive people don’t suffer but they do have easier access to opportunities that the average citizen does not.

EDIT2: Okay so I’m really enjoyi

... keep reading on reddit ➑

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πŸ“…︎ Jan 12 2022
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This subreddit is 10 years old now.

I'm surprised it hasn't decade.

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πŸ‘€︎ u/frexyincdude
πŸ“…︎ Jan 14 2022
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Dropped my best ever dad joke & no one was around to hear it

For context I'm a Refuse Driver (Garbage man) & today I was on food waste. After I'd tipped I was checking the wagon for any defects when I spotted a lone pea balanced on the lifts.

I said "hey look, an escaPEA"

No one near me but it didn't half make me laugh for a good hour or so!

Edit: I can't believe how much this has blown up. Thank you everyone I've had a blast reading through the replies πŸ˜‚

πŸ‘︎ 19k
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πŸ‘€︎ u/Vegetable-Acadia
πŸ“…︎ Jan 11 2022
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What starts with a W and ends with a T

It really does, I swear!

πŸ‘︎ 6k
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πŸ‘€︎ u/PsychedeIic_Sheep
πŸ“…︎ Jan 13 2022
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What is a a bisexual person doing when they’re not dating anybody?

They’re on standbi

πŸ‘︎ 11k
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πŸ‘€︎ u/Toby-the-Cactus
πŸ“…︎ Jan 12 2022
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Geddit? No? Only me?
πŸ‘︎ 6k
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πŸ‘€︎ u/shampy311
πŸ“…︎ Dec 28 2021
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I wanna hear your best airplane puns.

Pilot on me!!

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πŸ‘€︎ u/Paulie_Felice
πŸ“…︎ Jan 07 2022
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E or ß?
πŸ‘︎ 9k
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πŸ‘€︎ u/Amazekam
πŸ“…︎ Jan 03 2022
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OP asks AITA if he's the asshole for selling his PS5 rather than sharing it [NEW UPDATE]

I'm not either OPs. This is a repost.

(The earlier updates have been shared here, but the last two haven't. That's the new update I'm referring to.)

Original Post - by u/Throwaway_dadisadoof

AITA for selling my PS5 rather than sharing it with my step brothers?

My (15, M) mum and dad met and briefly dated while they were both studying at uni. My mum gave birth to me after they had broken up and had to sue my dad for child support. I was raised by my mum and had virtually nothing to do with my dad throughout my childhood. My mum was an international student and her family cut ties with her due to the circumstances of my birth. Tragically, two years ago, I lost my mum to cancer and thus I was placed under the care of my dad.

My dad has remarried and has two sons (5 and 7) with his wife. It wasn’t a bad arrangement at first, but we were all essentially strangers. I was given a bedroom to myself and we shared some meals but other than kept to myself.

About 10 months ago, I was lucky enough to score a casual job at an aged care facility as IT support. It was stupid easy money as it involves installing and maintaining a dozen or so common PCs used by the residents plus running basic computing workshops.

I ended up accruing a whole lot of disposable income in a short time. Stupidly, instead of just keeping quiet about it, I decked out my room with a new TV, headphone and a PS5. Obviously, this setup was of great interest to my two step-brothers. Initially, my rule was that they could play the PS5 anytime I wasn’t using it but I would get first dibs if I wanted to play or use my TV. I was also super accommodating by buying an extra controller (which I didn’t need) and several kid friendly games that they wanted to play. I eventually had to change the rule to β€˜only play when I was there’ because the 5 y.o destroyed one my controllers through spilling juice on it. This is where the drama started.

They whined to my β€˜parents’ who then β€˜ordered’ me to place the PS5 in the living room. I refused stating that I had purchased it with my own money. This led to their argument that I have too much money and should contribute rent, utilities and food money. I called their bluff and said β€˜sure, draw up a contract and I’ll get a lawyer to review it to ensure it complies with the Family Law Ac

... keep reading on reddit ➑

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πŸ‘€︎ u/GoodGirlsGrace
πŸ“…︎ Jan 13 2022
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What did Spartacus say when the lion ate his wife?

Nothing, he was gladiator.

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πŸ‘€︎ u/rj104
πŸ“…︎ Jan 15 2022
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Pun intended.
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πŸ‘€︎ u/Sharmaji1301
πŸ“…︎ Jan 15 2022
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No spoilers
πŸ‘︎ 9k
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πŸ‘€︎ u/Onfour
πŸ“…︎ Jan 06 2022
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Covid problems
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πŸ‘€︎ u/theincrediblebou
πŸ“…︎ Jan 12 2022
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These aren't dad jokes...

Dad jokes are supposed to be jokes you can tell a kid and they will understand it and find it funny.

This sub is mostly just NSFW puns now.

If it needs a NSFW tag it's not a dad joke. There should just be a NSFW puns subreddit for that.

Edit* I'm not replying any longer and turning off notifications but to all those that say "no one cares", there sure are a lot of you arguing about it. Maybe I'm wrong but you people don't need to be rude about it. If you really don't care, don't comment.

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πŸ‘€︎ u/Lance986
πŸ“…︎ Dec 15 2021
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What did 0 say to 8 ?

What did 0 say to 8 ?

" Nice Belt "

So What did 3 say to 8 ?

" Hey, you two stop making out "

πŸ‘︎ 9k
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πŸ‘€︎ u/designjeevan
πŸ“…︎ Jan 03 2022
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Spi__
πŸ‘︎ 6k
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πŸ‘€︎ u/Fast_Echidna_8520
πŸ“…︎ Jan 11 2022
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TIFUpdate: Called the girl who ghosted me (final post)

So my original post blew up because... well I am an idiot.

Called the girl who ghosted me

TL;DR: met girl at coffee shop. Couple dates. Got ghosted for about 3 weeks. She shows up pregnant.

A couple months go by and of course we go for an ultra sound....

second post

TL;DR: TWINS! And pregnant one is moving in....

This is my last update. Thank you for your kind words and support. So for the past few months, we have been living together. Madness has followed...

I noticed that pickles kept disappearing.. Leah would be ever so helpful helping me look for them.. so there was a pickle thief in the house. Leah couldn't figure it out either... but she swears it wasn't her.. how can I doubt a pregnant female who says she didn't eat all the pickles?

Chili cheese dog runs at 9 at night? Absolutely! Count me in!

Crying because my cat looked at her and licked it's paw and it was the cutest thing ever? I got hugs to cure that...

Talking to belly asking if they want to come out... I can ignore that so she doesn't think that I think she is completely crazy.. covered that...

We have been living together for a few months now. And her water broke last Saturday.

Rushed to the hospital and the usual madness ensued. And a few hours later, there were two more people in this world...

And to stop all doubts... paternity test was taken. And the crowd at Maury would go nuts... I am the father!!!

So my kiddos were born healthy and happy. We are all home now and spending the holiday at home since family member who were vaccinated got covid.. so just me and my new family.

I was a person who never wanted kids. But for the life of me.... I can't remember why. I am so full of joy and pride. I have been taking naps with the kiddos and changing diapers... the world is crazy but my little slice of madness keeps me smiling! And I felt that I should put in the final ending of my adventures.

Also, because of the first post... my son is named Ben!

Have a Merry Christmas TIFU!

TL;DR: I am the father of the twins from the girl who ghosted me!

Update edit: fuck my inbox...

Ok. I have gotten paternity test and yes I am the father. I stated this in the post but will put it here for clarification. I A

... keep reading on reddit ➑

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πŸ“…︎ Dec 24 2021
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I dislike karma whores who make posts that imply it's their cake day, simply for upvotes.

I won't be doing that today!

πŸ‘︎ 15k
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πŸ‘€︎ u/djcarves
πŸ“…︎ Dec 27 2021
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The Ancient Romans II
πŸ‘︎ 6k
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πŸ‘€︎ u/mordrathe
πŸ“…︎ Dec 29 2021
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I'd like to dedicate this joke to my wisdom teeth.

[Removed]

πŸ‘︎ 6k
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πŸ‘€︎ u/ThoughtPumP
πŸ“…︎ Jan 14 2022
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I did it, I finally did it. After 4 years and 92 days I went from being a father, to a dad.

This morning, my 4 year old daughter.

Daughter: I'm hungry

Me: nerves building, smile widening

Me: Hi hungry, I'm dad.

She had no idea what was going on but I finally did it.

Thank you all for listening.

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πŸ‘€︎ u/Sk2ec
πŸ“…︎ Jan 01 2022
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It this sub dead?

There hasn't been a post all year!

πŸ‘︎ 13k
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πŸ‘€︎ u/TheTreelo
πŸ“…︎ Jan 01 2022
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How do you stop Canadian bacon from curling in your frying pan?

You take away their little brooms

πŸ‘︎ 6k
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πŸ‘€︎ u/Majorpain2006
πŸ“…︎ Jan 09 2022
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School Was Clothed
πŸ‘︎ 5k
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πŸ‘€︎ u/Kennydoe
πŸ“…︎ Jan 08 2022
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Letting loose with these puns
πŸ‘︎ 6k
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πŸ“…︎ Jan 13 2022
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Couch potato
πŸ‘︎ 8k
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πŸ“…︎ Dec 31 2021
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Baka!
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πŸ‘€︎ u/ridi86
πŸ“…︎ Jan 09 2022
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I had a vasectomy because I didn’t want any kids.

When I got home, they were still there.

πŸ‘︎ 10k
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πŸ‘€︎ u/demotrek
πŸ“…︎ Jan 13 2022
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