Targeted Drug Delivery Puns

Explains the DDS pill rather well.

"Recently, a variety of “smart” devices have garnered interest in the pharmaceutical industry. These devices range from ingestible sensors to electronic pill capsules. The majority of the smart technologies are limited to detection and monitoring. The DDS2 is a novel electronic pill which has elements of the IntelliCap system and a localization technology that relies on GI anatomy rather than physiology for targeted drug delivery. It is a nondegradable capsule housed in a shell that separates an electronics system and actuator from the exterior environment. While in transit, outward facing LEDs flash and illuminate the surrounding tissue. When reflected light reaches the photodetectors in the capsule, the internal algorithm determines the correct anatomical location to enable local delivery of the encapsulated drug. The DDS2 is programmed to recognize transition through the ileocecal valve and into the cecum to trigger drug release."

https://academic.oup.com/crohnscolitis360/article/3/4/otab045/6317024

Journal of the American Chemical SocietyDOI: 10.1021/jacs.1c03013

Zhiyong Huang, Dan Wang, Cheng-Yu Long, Shen-Huan Li, Xue-Qiang Wang, and Weihong Tan

https://ift.tt/3v7OzZA

Journal of the American Chemical SocietyDOI: 10.1021/jacs.9b09782

https://ift.tt/2t5u1XQ

I am a researcher participating in the NIH I-Corps program for a start-up biopharmaceutical company, POP Biotechnologies, seeking to validate the potential of a unique light-activated drug delivery system for the localized and enhanced treatment of discrete tumors. As an SBIR awardee, we are working to refine our clinical development plan through participation in the NIH I-Corps program.

POP Biotechnologies is exploring inflammatory breast cancer and cutaneous lesions associated with breast cancer as first-in-human clinical targets and seeking to identify other commercially viable targets compatible with their approach.

In support of our research, I am looking to interview people involved in the treatment of inflammatory breast cancer or cutaneous metastatic breast cancer. I am looking to conduct 10-15 minute interviews regarding treatment processes, support services, or other activities involved in planning / implementing treatment.

If you, or someone you know, would be interested in participating in an interview, please send me a PM -- it would be really helpful.

I will happily send a nonconfidential summary of our technology to anyone interested, you can read more about our approach at http://popbiotech.com/oncology.html

Recent related publications:

Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

https://www.sciencedirect.com/science/article/pii/S0168365919300574

Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin
http://mct.aacrjournals.org/content/18/3/592

Chemophototherapy: An Emerging Treatment Option for Solid Tumors - Luo - 2018 - Advanced Science - Wiley Online Library
https://onlinelibrary.wiley.com/doi/full/10.1002/advs.201600106%4010.1002/%28ISSN%292198-3844.Health-Medical-Life-Sciences#.XM5QTkwLXDs.reddit

Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release
https://www.sciencedirect.com/science/article/pii/S0142961215008315

As CJ Logistics Corporation's / CJ Korea Express (CJ대한통운) strike (delivery strike/택배파업) is prolonged, the damage to buyers who need to receive the package is increasing over time. I ordered the package on December 26, 2021, and the company that will deliver the courier is CJ Korea Express, and it arrived at Seosan Hub normally. But two days later on the 28th, the company's labor union began an indefinite strike, and my package there remained in one place as if it were a criminal serving a life sentence in prison. On December 31, I tried to call the CJ Korea Express Customer Center and Seosan Hub Customer Center to pick up the package directly to Seosan Hub, but failed, and I decided to return and refund the package (goods) after receiving a call from the seller at 5 p.m. the day before yesterday.

Coupang can also be an alternative to that, but the delivery company may be determined by CJ Korea Express by a certain chance, so you have to face the worst situation where you can never get it if you don't have any luck.

The link at the bottom which is lead to chart shows the strike area of CJ Korea Express. If you are a target of strike area, you have no luck at all.

PLEASE NOTE that the dong(동/洞) area is based on the legal dong(법정동), and the contents may not be accurate because the strike targeted area MAY BE omitted, excluded or added.

Red marked area are included the ENTIRE strike targeted area, orange marked area are included the MOST strike targeted area, and blue marked areas are EXCLUDED(not included) from the strike targeted area and where delivery is normally available.

You can search the strike area conveniently and quickly by using Ctrl + F.

I originally tried to chart it here, but it was very difficult to write a chart on Reddit, so please understand that I attached the link. - Delivery Strike Targeted Area in English (PDF)

If you want to search the strike targeted area in Korean, it is convenient to go to my blog link. (This link is NOT for promotional purposes, and it reveals the link attached for convenience.) - Delivery Strike Targeted Area in Korean

I am a researcher participating in the NIH I-Corps program for a start-up biopharmaceutical company, POP Biotechnologies, seeking to validate the potential of a unique light-activated drug delivery system for the localized and enhanced treatment of discrete tumors. As an SBIR awardee, we are working to refine our clinical development plan through participation in the NIH I-Corps program.

POP Biotechnologies is exploring inflammatory breast cancer and cutaneous lesions associated with breast cancer as first-in-human clinical targets and seeking to identify other commercially viable targets compatible with their approach.

In support of our research, I am looking to interview people involved in the treatment of inflammatory breast cancer or cutaneous metastatic breast cancer. I am looking to conduct 10-15 minute interviews regarding treatment processes, support services, or other activities involved in planning / implementing treatment. Any kind of stakeholder, customer, or patient would be helpful.

If you, or someone you know, would be interested in participating in an interview, please send me a PM -- it would be really helpful.

I will happily provide copies of the most interesting publications or a nonconfidential summary of our technology to anyone interested, you can read more about our approach at http://popbiotech.com/oncology.html