Abstract: PMDD is a mood disorder that affects approximately 3% of menstruating women in the luteal phase of the menstrual cycle. The symptoms of PMDD have significant overlap with the symptoms of hypocalcemia. A literature review shows that women with PMDD have significantly lower urine calcium values in the luteal phase as well as lower plasma levels of 1,25(OH)2 vitamin D and IGF-1. These lower calciotropic hormone values lead to impaired bone calcium and access and lower intestinal absorption. Testing these values would allow clinicians to monitor these micronutrient deficiencies and the effectiveness of supplementation in their patients.
I think we all know what PMDD is so I'm going to skip some of the introduction.
Introduction:
There is significant symptom overlap between PMDD and hypocalcemia which begs the question of whether PMDD causes hypocalcemia or if the symptoms of PMDD are exacerbated by an underlying calcium deficiency. Monitoring calcium levels in women with PMDD and addressing low levels could provide a simple, low-cost intervention that may improve the symptomology of women with PMDD.
PMDD: Depression (sadness, lethargy, social isolation, decreased motivation), Anxiety (insomnia, paresthesia), Fatigue, Irritability, Labile mood, Food cravings, Edema, Bloating, Abdominal cramps, Headache, Generalized aches and pain
Hypocalcemia: Depression, Anxiety, Paresthesia, Fatigue, Impaired memory, Impaired intellectual capacity, Personality disturbances, Neuromuscular irritability, Muscle cramps, Tetany
The average adult human body contains around 1000 grams of calcium, 99% of which is in the form of hydroxyapatite and is located in the skeleton. One percent of calcium is found in the extracellular fluid. In blood 50% of this calcium is ionized and measurable while 40% is protein bound and 10% is complexed with citrate and phosphate. Diet is our only source of calcium, and the only loss of calcium is excretion in the urine. Vitamin D and parathyroid hormone (PTH) are the most important up-regulators. While calcitonin is the most important down-regulator. Vitamin D is a transcription factor that increases intestinal absorption. PTH increases renal tubule reabsorption and hydroxylation of 25(OH) vitamin D to the active form 1,25 (OH)2 Vitamin D as well as increasing calcium levels by stimulating osteoclast activity and bone breakdown. 12
The menstrual cycle is divided into two primary phases; the follicular phase which starts on the first da
... keep reading on reddit ➡Link to the website: https://gitsearcher.com/
I’ve been working in data science for 15+ years, and over the years, I’ve found so many awesome data science GitHub repositories, so I created a site to make it easy to explore the best ones.
The site has more than 5k resources, for 60+ languages (but mostly Python, R & C++), in 90+ categories, and it will allow you to:
- Have access to detailed stats about each repository (commits, number of contributors, number of stars, etc.)
- Filter by language, topic, repository type and more to find the repositories that match your needs.
Hope it helps! Let me know if you have any feedback on the website.
I am a bit pissed right now. For A-Level (exams you do when 17-18 in UK) computer science, my exam board, OCR, won't let me use GameMaker Studio 2, which would make my life much easier as I have about 5 years of experience in it! I would be fine with this if they actually provided a good reason, but the response I received from them is the exact opposite!
>"Thanks for your email query. GameMaker allows too much pre-generation of code – and the A-level programming project requires students to write a significant amount of code themselves. Therefore it becomes hard to know what they have written, what the software application has generated, and therefore what they can gain credit for.Subject to further feedback from our Principal Moderator, we are still mindful of the fact that students can convert drag and drop into code and therefore not willing to allow GameMaker at this moment for A Level projects.Unity, Monkey X and Unreal game engine are allowed, as are other high-level languages such as Python, Java and C# - all of which can be used to create games.GoDot allows visual scripting and we have allowed students to use GoDot Engine for their A Level programming project. Care must be taken while candidates codes the core of this manually through use of C++ and the like. Using pre-built templates is allowed - but credit can only be given to authentic candidate generated code/modifications - and these should form a significant part of the project."
I am yet to find out what "pre-generation of code" means. I assume it meant drag and drop, so I contacted the exam board to elaborate. I said...
>I realise that the drag and drop feature in Gamemaker could be misinterpreted as pre-generating code, however, as someone with 5 years of experience in a plethora of different versions of the engine (v1.4, v2.0 to v2.3+), I can assure you that the use of drag and drop is severely limited, and therefore absolutely would not be acceptable (and of aid) in the A-Level programming project. Drag and Drop is, in all reality, an advertising tool, and a way to bring in young and amateur programmers to the game making scene, without “scaring them away” with the unusual sight of programming languages, and the necessity for syntax. Obviously, after getting used to the designing of algorithms, programming skills can be introduced in Gamemaker’s “GML” (Gamemaker Language), which shares syntax with languages like Python, or JavaScript. Ove
... keep reading on reddit ➡
I finished this last night, and whew, what an odyssey this book is.
Andy Weir's writing style is actually perfectly suited for this kind of storytelling - the stakes are high (like, existentially high), but it never gets overbearingly foreboding or oppressive, and the light and breezy way with which his characters approach situations helps keep the book palatable even in situations where the tension is ramped up.
As far as speculative science fiction goes, I love where PHM goes - in terms of both, answers to questions about our past (where did we come from, why did we develop intelligence, and so on) to our future (will we ever encounter intelligent life elsewhere in the universe, how will we communicate with it, do we have a future off this planet?). As far as pure storytelling goes, it takes some unexpected swerves that lead to some engaging and extremely satisfying payoffs and developments later.
Obviously by definition, this book is substantially less grounded (and therefore "plausible") than The Martian, but I legitimately think it comes out better in the end because it's less shackled to the expectations of being grounded.
If you like science fiction at all, I can't recommend this one enough.
Currently I have ample free time in my semester which I really want to devote in some productive work, i have development experience as well as sound knowledge on cloud infrastructure like AWS.
I really want to explore the space of blockchain development
Hello everybody,
I'm opening thread in this subreddit as advised by mod.
I always wanted to be involved in any kind of scientific researches and try to give my humble contribution to it.
Since I was a kid,I planned to became paleontologist,but in my adolescence I developed sever agoraphobia combined with emetophobia that prevented me in achieving that.
I never lost my interest toward paleontology and science and I continue to learn about it online since that was my only option.
Since I have agoraphobia,it means I have basically unlimited free time and I would like to spend it on something meaningful.
I recently discovered by pure accident that online volunteering exists and that people without any experience in field can participate in some projects.
I read that Zooniverse is one biggest websites for participation in various citizen science projects and I was wondering how meaningful are those projects to real scientists in reality?
From what I managed to found online,It's seems like a useful tool for crowd sourcing mass data that computers have a hard time processing.
But is there any real data and useful information that can be obtained by scientists for their researches from participants in this programs?
I would really dedicate myself on doing everything I can to do my contribution since I'm having troubles leaving my home and got tons of free time,but I don't want to spend months and months doing something that may not have any real usage to scientific community.If that's the case I'd rather spend that time to expand my knowledge in other areas like geology etc.
So,after going into lot of details,I'm coming back to my original question:
Does citizen science projects like Zoouniverse have any meaningful impact on real scientific research that would make them important at least to some degree?
Everyone's opinion is more than welcome so feel free to write anything,I'd be glad to hear it.
Thank you for taking time to read this and have a nice day.
Can I call a lawyer and drag him in front of a court to get some kind of compensation for my losses? Is he legally responsible because Ultron is his product? Do I sue him in a US court? Because the Sokovian courthouse is just straight-up gone.
If I can't sue, I have a backup plan involving an abandoned Hydra bunker, an EMP bomb, and a certain combination of words, but I would much rather settle this inside the law if possible.
I need worker ants for a science project. Where would I be able to buy them and what would else would I need to buy to keep them living until I am finished?
Hi everyone, I have completed the offworld mission (4/5 towards a science victory) but I can't seem to be able to kickoff the two laser projects to speed up the 50 light-years / turns.
I have plenty of science and production, as well as energy, and Spaceports in at least 3 cities. Are there other pre-requisites I'm missing out on?
(playing Dido, not sure it helps)
Please contact me asap
Could I get some help on it just if you could say pros, cons, what people would go through, what it would be like or anything really it would be appreciated
Hi guys,
I've been accepted for my first full-time role in a high-growth Finance start-up. Thing is, the company has only 1 technical person (the rest are product, sales, marketing, etc.) and he basically runs the whole operation: Now they hired me as a sort of ,,data scientist'' but they don't really know what Data Science means (since they don't have any technical people in the team!)
Start-up is doing extremely well though and they plan to scale up ALOT this year. This basically translates into lots of customers coming in through registering on our platform (right now 1000+) and we save all of their profiles in our CRM which is just a huge cluttered mess. They expect me to clean it and generate valuable business reports.
Thing is I'm a complete beginner in Data Science but I do love coding and maths. I love writing my own solutions and algorithms to problems. Some things I've done so far.
- scrape lists of companies on the web via beautifulsoup
- parse data in PDFs and create pandas
- connect some tables with SQlite3 in order to give me queries
- Lots of excel sheet handling manually and with libs such as openpyxl, trying to remove duplicates in data sets etc.
- Connect to some APIs to get for example data from the register of companies
I feel like my approach is all over the place though and while there's high expectations on me at my role I have to learn a shit ton of stuff real quickly. I need some professional guidance - if you guys would start learning data science again and your first project is basically restructuring their whole CRM with 50'000+ entries, how would you do it (I know it's impossible for 1 person! But where should I start contributing? What's the most practical stuff I could learn?)
Thing is I lack a lot of technical skills right now but got the role bascially because I impressed them with my business knowledge (I worked in Sales before and I love interacting with customers).
Can you give me advice such as:
- forget openpyxl and just get really comfortable with pandas
- learn some data engineering practices for cleaning, structuring data (what's the best method for removing duplicates, etc.)
- Use Tableau, or some Python lib for visualization, or whatnot
- How to manage expectations, make decisions, work with people..
etc..
I'm very grateful for any practical advice,
Valuevow
So basically we were assigned a science project where we were given a city, and then based on the climate in that city we had to design a home that used renewable energy and was as green as possible. Me and my friends were assigned Kathmandu, Nepal, so we read about the city and apparently it rains a lot so we made a way to trap and filter all the rainwater, and also we put solar panels for the less rainy months. My friends don't play krunker, so i basically did everything using the krunker Editor. I also put a Cybertruck and a Lamorghini in my garage lmao.
Can be found here: https://abh037.github.io/
It’s definitely not anything groundbreaking and I’m still learning, so manage your expectations accordingly and all that, but I hope you all find it interesting nonetheless.
Hello Guys!
The title basically says all.
I am very interested in science. Especially in physics, chemistry and astronomy.
I also really like programming, especially with Arduino and other microcontrollers.
Now I am looking for interesting Arduino projects in the field of physics, chemistry or astronomy.
Would you have some project suggestions for me?
Thanks in advance! :)
book can include anything from graphic novels, to textbooks and any type of "book" in between. Just need what you usually pick print or digital.
https://preview.redd.it/y6gy8ghh3g781.png?width=828&format=png&auto=webp&s=131dc48bf746dfc24b67c6cf2274ee6f5e87a1ad
I’ve been working in data science for 15+ years, and over the years, I’ve found so many awesome data science GitHub repositories, so I created a site to make it easy to explore the best ones.
The site has more than 5k resources, for 60+ languages (but mostly Python, R & C++), in 90+ categories, and it will allow you to:
- Have access to detailed stats about each repository (commits, number of contributors, number of stars, etc.)
- Filter by language, topic, repository type, and more to find the repositories that match your needs.
Hope it helps! Let me know if you have any feedback on the website.
EDIT: Here is the link to the site: gitsearcher.com
